ATE533497T1 - Verfahren zur verwendung von hedgehog-kinase- antagonisten zur behandlung von hedgehog- vermittelten krebs - Google Patents

Verfahren zur verwendung von hedgehog-kinase- antagonisten zur behandlung von hedgehog- vermittelten krebs

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Publication number
ATE533497T1
ATE533497T1 AT06850419T AT06850419T ATE533497T1 AT E533497 T1 ATE533497 T1 AT E533497T1 AT 06850419 T AT06850419 T AT 06850419T AT 06850419 T AT06850419 T AT 06850419T AT E533497 T1 ATE533497 T1 AT E533497T1
Authority
AT
Austria
Prior art keywords
hedgehog
kinase antagonists
treat
hedgehog signaling
well
Prior art date
Application number
AT06850419T
Other languages
English (en)
Inventor
SAUVAGE Frederic DE
Marie Evangelista
Original Assignee
Genentech Inc
Curis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Curis Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE533497T1 publication Critical patent/ATE533497T1/de

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
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AT06850419T 2005-12-27 2006-12-13 Verfahren zur verwendung von hedgehog-kinase- antagonisten zur behandlung von hedgehog- vermittelten krebs ATE533497T1 (de)

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PCT/US2006/062052 WO2007089367A2 (en) 2005-12-27 2006-12-13 Use hedgehog kinase antagonists to inhibit hedgehog signaling and to treat cancer

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EP2806948B1 (de) 2012-01-27 2020-01-15 New York University Verfahren zur verbesserung von remyelinisierung unter verwendung von gli1-inhibitoren
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WO2014201133A1 (en) * 2013-06-11 2014-12-18 President And Fellows Of Harvard College Compositions and methods for improving induced neuron generation
KR101451227B1 (ko) * 2014-03-06 2014-10-15 강원대학교산학협력단 Pka 활성을 이용한 암 진단용 조성물 및 암 전이 진단을 위한 정보제공 방법
KR101430209B1 (ko) * 2014-03-06 2014-08-14 강원대학교산학협력단 단백질 키나아제 활성 측정 방법 및 이를 위한 키트
PL3302428T3 (pl) 2015-06-04 2026-04-13 Sol-Gel Technologies Ltd. Preparaty do zastosowania miejscowego do dostarczania związków inhibitora hedgehog i ich zastosowanie
CN111527407B (zh) * 2018-03-09 2023-09-15 株式会社漫丹 免疫相关疾病的指标的检测方法
WO2019246593A2 (en) * 2018-06-22 2019-12-26 Fred Hutchinson Cancer Research Center Compositions and methods to target cll-1 and cd123 for the treatment of acute myeloid leukemia and related disorders
CN114317398B (zh) * 2020-09-27 2024-03-01 中国科学院分子细胞科学卓越创新中心 Gli1和EpCAM基因共同标记的肝祖细胞群及其应用
CN116042797B (zh) * 2022-07-07 2026-01-30 中南大学湘雅二医院 circSCAPER的应用、银屑病诊断/或者治疗制剂
WO2025064753A1 (en) * 2023-09-20 2025-03-27 Rutgers, The State University Of New Jersey Inhibition of hepatic glycerol metabolism as a treatment for hypertriglyceridemia and fatty liver disease

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US20070179091A1 (en) 2007-08-02
ES2377885T3 (es) 2012-04-02
AU2006337085B2 (en) 2013-12-19
WO2007089367A2 (en) 2007-08-09
CA2635718A1 (en) 2007-08-09
EP1978973A2 (de) 2008-10-15
AU2006337085A1 (en) 2007-08-09
JP2009526752A (ja) 2009-07-23
AU2006337085A8 (en) 2009-02-19
EP1978973B1 (de) 2011-11-16

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