ATE534909T1 - Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäuren - Google Patents
Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäurenInfo
- Publication number
- ATE534909T1 ATE534909T1 AT05855111T AT05855111T ATE534909T1 AT E534909 T1 ATE534909 T1 AT E534909T1 AT 05855111 T AT05855111 T AT 05855111T AT 05855111 T AT05855111 T AT 05855111T AT E534909 T1 ATE534909 T1 AT E534909T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acids
- natural amino
- proteins
- proteomic profiling
- reagents
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000001243 protein synthesis Methods 0.000 abstract 1
- 238000000575 proteomic method Methods 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Physiology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63885604P | 2004-12-22 | 2004-12-22 | |
| US66847105P | 2005-04-05 | 2005-04-05 | |
| PCT/US2005/046496 WO2006069203A2 (en) | 2004-12-22 | 2005-12-21 | Methods for proteomic profiling using non-natural amino acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE534909T1 true ATE534909T1 (de) | 2011-12-15 |
Family
ID=36602311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05855111T ATE534909T1 (de) | 2004-12-22 | 2005-12-21 | Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäuren |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US20060216760A1 (de) |
| EP (2) | EP1828780B1 (de) |
| AT (1) | ATE534909T1 (de) |
| WO (1) | WO2006069203A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1415156B1 (de) | 2001-07-10 | 2009-09-02 | The Board Of Trustees Of The Leland Stanford Junior University | Verfahren und zusammensetzungen zum nachweis des aktivierungszustands multipler proteine in einzelzellen |
| US7393656B2 (en) | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
| US7381535B2 (en) | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
| WO2006069203A2 (en) | 2004-12-22 | 2006-06-29 | California Institute Of Technology | Methods for proteomic profiling using non-natural amino acids |
| BRPI0617191A2 (pt) * | 2005-10-12 | 2011-07-19 | Scripps Research Inst | modificação pós-traducional de polipeptìdeos expressos em fagos |
| WO2007047668A2 (en) * | 2005-10-14 | 2007-04-26 | California Institute Of Technology | Use of non-canonical amino acids as metabolic markers for rapidly-dividing cells |
| EP2060584A1 (de) * | 2007-10-16 | 2009-05-20 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zur Herstellung von Proteinen mit chemisch funktionalisierten N-Termini |
| WO2012054784A1 (en) | 2010-10-20 | 2012-04-26 | Li-Cor, Inc. | Fluorescent imaging with substituted cyanine dyes |
| US10281468B2 (en) * | 2014-02-28 | 2019-05-07 | Dh Technologies Development Pte. Ltd. | Microbial identification and quantitation using MS cleavable tags |
| WO2018042454A2 (en) * | 2016-09-01 | 2018-03-08 | Translational Health Science And Technology Institute (Thsti) | Method of hyperplexing in mass spectrometry to elucidate temporal dynamics of proteome |
| JP7609793B2 (ja) * | 2019-03-04 | 2025-01-07 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | バイオコンジュゲーションのために操作されたｃｄ４７の細胞外ドメイン |
| US20230236170A1 (en) * | 2019-10-15 | 2023-07-27 | Jnana Therapeutics Inc. | Reactive affinity probe-interaction discovery platform |
| WO2021164694A1 (zh) * | 2020-02-17 | 2021-08-26 | 中国科学院生物物理研究所 | 抗体筛选方法 |
| CN114075588B (zh) * | 2020-07-29 | 2024-07-09 | 中国科学院上海有机化学研究所 | 一种高特异性的细胞分泌蛋白富集方法 |
| CA3215311A1 (en) | 2021-04-01 | 2022-10-06 | The Regents Of The University Of California | Genetic modification of mammalian cells to confer resistance to csf1r antagonists |
| JP7790088B2 (ja) * | 2021-10-27 | 2025-12-23 | 東ソー株式会社 | セクレトーム検出方法及びｔ細胞標識用培地 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US6596476B1 (en) * | 1989-12-22 | 2003-07-22 | Abbott Laboratories | Hepatitis C assay |
| US6013434A (en) * | 1989-12-22 | 2000-01-11 | Howard Florey Institute Of Experimental Physiology And Medicine | Oligonucleotide-polyamide conjugates |
| US5326856A (en) | 1992-04-09 | 1994-07-05 | Cytogen Corporation | Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding |
| US5538897A (en) | 1994-03-14 | 1996-07-23 | University Of Washington | Use of mass spectrometry fragmentation patterns of peptides to identify amino acid sequences in databases |
| US5986076A (en) | 1994-05-11 | 1999-11-16 | Trustees Of Boston University | Photocleavable agents and conjugates for the detection and isolation of biomolecules |
| EP0776330B1 (de) | 1994-06-23 | 2003-08-20 | Affymax Technologies N.V. | Photolabile verbindungen und verfahren für deren verwendung |
| US5846782A (en) * | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US8409564B2 (en) * | 1999-10-05 | 2013-04-02 | Universite De Montreal | Rhodamine derivatives for photodynamic diagnosis and treatment |
| AU2001281463A1 (en) | 2000-03-16 | 2001-09-24 | The Regents Of The University Of California | Chemoselective ligation |
| US6586207B2 (en) | 2000-05-26 | 2003-07-01 | California Institute Of Technology | Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues |
| JP2004536578A (ja) * | 2001-03-30 | 2004-12-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 腫瘍ターゲティング用の抗−ｍｕｃ−１単鎖抗体 |
| WO2003073238A2 (en) | 2002-02-27 | 2003-09-04 | California Institute Of Technology | Computational method for designing enzymes for incorporation of amino acid analogs into proteins |
| US7449558B2 (en) * | 2003-10-30 | 2008-11-11 | National University Of Singapore | Site-specific labelling of proteins |
| US20060057069A1 (en) * | 2004-06-07 | 2006-03-16 | California Institute Of Technology | Detection of protein expression in vivo using fluorescent puromycin conjugates |
| EP1766409A2 (de) * | 2004-06-18 | 2007-03-28 | Molecular Probes, Inc. | Fluoreszierende isotop-etiketten und verfahren zu ihrer verwendung |
| US7807619B2 (en) * | 2004-11-01 | 2010-10-05 | The Regents Of The University Of California | Compositions and methods for modification of biomolecules |
| WO2006069203A2 (en) | 2004-12-22 | 2006-06-29 | California Institute Of Technology | Methods for proteomic profiling using non-natural amino acids |
-
2005
- 2005-12-21 WO PCT/US2005/046496 patent/WO2006069203A2/en not_active Ceased
- 2005-12-21 AT AT05855111T patent/ATE534909T1/de active
- 2005-12-21 EP EP05855111A patent/EP1828780B1/de not_active Expired - Lifetime
- 2005-12-21 US US11/314,323 patent/US20060216760A1/en not_active Abandoned
- 2005-12-21 EP EP10181451.5A patent/EP2290369B1/de not_active Expired - Lifetime
-
2017
- 2017-04-24 US US15/495,414 patent/US20170292958A1/en not_active Abandoned
-
2020
- 2020-10-09 US US17/067,028 patent/US20210223252A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20170292958A1 (en) | 2017-10-12 |
| EP1828780B1 (de) | 2011-11-23 |
| US20210223252A1 (en) | 2021-07-22 |
| WO2006069203A3 (en) | 2007-02-22 |
| EP1828780A2 (de) | 2007-09-05 |
| WO2006069203A2 (en) | 2006-06-29 |
| EP2290369A1 (de) | 2011-03-02 |
| EP2290369B1 (de) | 2013-08-14 |
| US20060216760A1 (en) | 2006-09-28 |
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