ATE536193T1 - Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren - Google Patents

Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren

Info

Publication number
ATE536193T1
ATE536193T1 AT05763212T AT05763212T ATE536193T1 AT E536193 T1 ATE536193 T1 AT E536193T1 AT 05763212 T AT05763212 T AT 05763212T AT 05763212 T AT05763212 T AT 05763212T AT E536193 T1 ATE536193 T1 AT E536193T1
Authority
AT
Austria
Prior art keywords
cells
encapsulation
coacervation
scaffolds
biologically compatible
Prior art date
Application number
AT05763212T
Other languages
English (en)
Inventor
Hanry Yu
Yi Chin Toh
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Application granted granted Critical
Publication of ATE536193T1 publication Critical patent/ATE536193T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A61L27/165—Rubbers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT05763212T 2004-07-26 2005-07-22 Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren ATE536193T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/899,899 US7704714B2 (en) 2004-07-26 2004-07-26 Encapsulation of cells in biologic compatible scaffolds by coacervation of charged polymers
PCT/SG2005/000249 WO2006011855A1 (en) 2004-07-26 2005-07-22 Encapsulation of cells in biologic compatible scaffolds by coacervation of charged polymers

Publications (1)

Publication Number Publication Date
ATE536193T1 true ATE536193T1 (de) 2011-12-15

Family

ID=35657710

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05763212T ATE536193T1 (de) 2004-07-26 2005-07-22 Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren

Country Status (4)

Country Link
US (2) US7704714B2 (de)
EP (1) EP1781347B1 (de)
AT (1) ATE536193T1 (de)
WO (1) WO2006011855A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1989144A4 (de) * 2006-02-02 2014-01-29 Innovative Bio Therapies Extrakorporale zellbasierte therapeutische vorrichtung und freisetzungssystem
US20090081296A1 (en) * 2006-02-02 2009-03-26 Humes H David Extracorporeal cell-based therapeutic device and delivery system
CN101500512B (zh) * 2006-02-07 2011-08-24 脊柱赛特有限公司 使用生物反应器的修复软骨的方法和组合物
DE102006054789B4 (de) * 2006-11-21 2008-09-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zur Behandlung biologischer Zellen auf einem Substrat
WO2008069761A1 (en) * 2006-12-05 2008-06-12 Nanyang Technological University Manufacturing three-dimensional scaffolds using cryogenic prototyping
US20100190254A1 (en) 2006-12-05 2010-07-29 Nanyang Technological University Three-dimensional porous hybrid scaffold and manufacture thereof
WO2008149129A1 (en) * 2007-06-08 2008-12-11 Nova Thera Limited Cell expansion
WO2009045370A2 (en) 2007-09-28 2009-04-09 Intrexon Corporation Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
EP2203548A4 (de) * 2007-10-11 2014-01-15 Agency Science Tech & Res Bildung einer zellstruktur mit transientem linker in einem käfig
CN102171332A (zh) * 2008-06-18 2011-08-31 创新生物制剂疗法公司 促进肾前体细胞增殖的方法
KR101361416B1 (ko) 2008-10-08 2014-02-21 인트렉손 코포레이션 다수의 면역조절자를 발현하는 조작된 세포 및 그 용도
EP2266635A1 (de) * 2009-06-26 2010-12-29 Aarhus Universitet Hybridgerüst mit dreidimensionaler Nanostruktur und Herstellung davon
KR101335176B1 (ko) * 2011-12-12 2013-11-29 테고사이언스 (주) 상처 치유용 드레싱재제
TWI512103B (zh) 2012-11-12 2015-12-11 Ind Tech Res Inst 細胞培養系統、以及無血清細胞培養方法
KR101461161B1 (ko) * 2013-01-15 2014-11-13 단국대학교 천안캠퍼스 산학협력단 3차원 공극 구조를 포함하는 골 재생용 나노합성 스캐폴드
JP2016523083A (ja) 2013-06-19 2016-08-08 スパイナルサイト， エルエルシー 軟骨細胞適用のための脂肪細胞
US9265533B2 (en) 2013-09-04 2016-02-23 Aesculap Implant Systems, Llc Rod persuader, system and method
CN103705984B (zh) * 2013-12-17 2016-06-15 南京大学医学院附属鼓楼医院 胶原支架复合骨髓间充质干细胞制备方法及应用
US20190241849A1 (en) * 2016-08-31 2019-08-08 University Of Kansas Expandable cell culture substrate
WO2018044124A1 (ko) * 2016-09-01 2018-03-08 포항공과대학교 산학협력단 신규한 줄기 세포 전달체 및 이의 제조 방법
TR201713643A2 (tr) * 2017-09-15 2019-03-21 Univ Yeditepe Koaservasyon yöntemi̇ i̇le koaservat üreti̇mi̇ yöntemi̇ ve bu üreti̇m yöntemi̇ i̇le elde edi̇len koaservatlar ve bunlarin doku i̇skelesi̇ olarak kullanimi
CN111249174A (zh) * 2020-02-24 2020-06-09 华熙生物科技股份有限公司 双壳-核结构的组合物及其制备方法
US20240066143A1 (en) * 2022-08-31 2024-02-29 Sichuan University Natural-polyphenols-based multi-stage porous hydrogel sustained release drug delivery system and its preparation method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054142A (en) * 1996-08-01 2000-04-25 Cyto Therapeutics, Inc. Biocompatible devices with foam scaffolds
WO1999047186A1 (en) * 1998-03-18 1999-09-23 University Of Pittsburgh Chitosan-based composite materials containing glycosaminoglycan for cartilage repair
US6730252B1 (en) * 2000-09-20 2004-05-04 Swee Hin Teoh Methods for fabricating a filament for use in tissue engineering
US6916640B2 (en) * 2000-10-12 2005-07-12 Agency For Science, Technology And Research Multi-layer cell encapsulation for tissue engineering

Also Published As

Publication number Publication date
US7704714B2 (en) 2010-04-27
WO2006011855A1 (en) 2006-02-02
WO2006011855A8 (en) 2006-04-06
US20100136649A1 (en) 2010-06-03
EP1781347A1 (de) 2007-05-09
EP1781347B1 (de) 2011-12-07
US20060019362A1 (en) 2006-01-26
US8343742B2 (en) 2013-01-01
EP1781347A4 (de) 2010-07-21

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