ATE536193T1 - Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren - Google Patents

Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren

Info

Publication number
ATE536193T1
ATE536193T1 AT05763212T AT05763212T ATE536193T1 AT E536193 T1 ATE536193 T1 AT E536193T1 AT 05763212 T AT05763212 T AT 05763212T AT 05763212 T AT05763212 T AT 05763212T AT E536193 T1 ATE536193 T1 AT E536193T1
Authority
AT
Austria
Prior art keywords
cells
encapsulation
coacervation
scaffolds
biologically compatible
Prior art date
Application number
AT05763212T
Other languages
English (en)
Inventor
Hanry Yu
Yi Chin Toh
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Application granted granted Critical
Publication of ATE536193T1 publication Critical patent/ATE536193T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A61L27/165—Rubbers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT05763212T 2004-07-26 2005-07-22 Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren ATE536193T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/899,899 US7704714B2 (en) 2004-07-26 2004-07-26 Encapsulation of cells in biologic compatible scaffolds by coacervation of charged polymers
PCT/SG2005/000249 WO2006011855A1 (en) 2004-07-26 2005-07-22 Encapsulation of cells in biologic compatible scaffolds by coacervation of charged polymers

Publications (1)

Publication Number Publication Date
ATE536193T1 true ATE536193T1 (de) 2011-12-15

Family

ID=35657710

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05763212T ATE536193T1 (de) 2004-07-26 2005-07-22 Verkapselung von zellen in biologisch kompatiblen gerüsten durch koazervation von beladenen polymeren

Country Status (4)

Country Link
US (2) US7704714B2 (de)
EP (1) EP1781347B1 (de)
AT (1) ATE536193T1 (de)
WO (1) WO2006011855A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090081296A1 (en) * 2006-02-02 2009-03-26 Humes H David Extracorporeal cell-based therapeutic device and delivery system
US8048419B2 (en) * 2006-02-02 2011-11-01 Innovative Biotherapies, Inc. Extracorporeal cell-based therapeutic device and delivery system
JP5269612B2 (ja) 2006-02-07 2013-08-21 スパイナルサイト， エルエルシー インビボバイオリアクターを使用する軟骨の修復のための方法および組成物
DE102006054789B4 (de) * 2006-11-21 2008-09-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zur Behandlung biologischer Zellen auf einem Substrat
WO2008069761A1 (en) * 2006-12-05 2008-06-12 Nanyang Technological University Manufacturing three-dimensional scaffolds using cryogenic prototyping
US20100190254A1 (en) 2006-12-05 2010-07-29 Nanyang Technological University Three-dimensional porous hybrid scaffold and manufacture thereof
TW200916583A (en) * 2007-06-08 2009-04-16 Novathera Ltd Cell expansion
MX2010003371A (es) * 2007-09-28 2010-05-05 Intrexon Corp Constructos interruptores genicos terapeuticos y biorreactores para la expresion de moleculas bioterapeuticas y usos de los mismos.
EP2203548A4 (de) 2007-10-11 2014-01-15 Agency Science Tech & Res Bildung einer zellstruktur mit transientem linker in einem käfig
AU2009327485A1 (en) * 2008-06-18 2010-06-24 Cytopherx, Inc. Methods for propagation of renal precursor cells
RU2573912C2 (ru) 2008-10-08 2016-01-27 Интрексон Корпорейшн Сконструированные клетки, экспрессирующие множественные иммуномодуляторы, и их применения
EP2266635A1 (de) * 2009-06-26 2010-12-29 Aarhus Universitet Hybridgerüst mit dreidimensionaler Nanostruktur und Herstellung davon
KR101335176B1 (ko) * 2011-12-12 2013-11-29 테고사이언스 (주) 상처 치유용 드레싱재제
TWI512103B (zh) 2012-11-12 2015-12-11 Ind Tech Res Inst 細胞培養系統、以及無血清細胞培養方法
KR101461161B1 (ko) * 2013-01-15 2014-11-13 단국대학교 천안캠퍼스 산학협력단 3차원 공극 구조를 포함하는 골 재생용 나노합성 스캐폴드
US10206954B2 (en) 2013-06-19 2019-02-19 Spinalcyte, Llc Adipose cells for chondrocyte applications
US9265533B2 (en) 2013-09-04 2016-02-23 Aesculap Implant Systems, Llc Rod persuader, system and method
CN103705984B (zh) * 2013-12-17 2016-06-15 南京大学医学院附属鼓楼医院 胶原支架复合骨髓间充质干细胞制备方法及应用
WO2018044990A1 (en) * 2016-08-31 2018-03-08 University Of Kansas Expandable cell culture substrate
WO2018044124A1 (ko) * 2016-09-01 2018-03-08 포항공과대학교 산학협력단 신규한 줄기 세포 전달체 및 이의 제조 방법
TR201713643A2 (tr) * 2017-09-15 2019-03-21 Univ Yeditepe Koaservasyon yöntemi̇ i̇le koaservat üreti̇mi̇ yöntemi̇ ve bu üreti̇m yöntemi̇ i̇le elde edi̇len koaservatlar ve bunlarin doku i̇skelesi̇ olarak kullanimi
CN111249174A (zh) * 2020-02-24 2020-06-09 华熙生物科技股份有限公司 双壳-核结构的组合物及其制备方法
US20240066143A1 (en) * 2022-08-31 2024-02-29 Sichuan University Natural-polyphenols-based multi-stage porous hydrogel sustained release drug delivery system and its preparation method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054142A (en) 1996-08-01 2000-04-25 Cyto Therapeutics, Inc. Biocompatible devices with foam scaffolds
AU3097999A (en) * 1998-03-18 1999-10-11 University Of Pittsburgh Chitosan-based composite materials containing glycosaminoglycan for cartilage repair
US6730252B1 (en) * 2000-09-20 2004-05-04 Swee Hin Teoh Methods for fabricating a filament for use in tissue engineering
AU2002213143A1 (en) * 2000-10-12 2002-04-22 Institute Of Materials Research And Engineering Non-disruptive three-dimensional culture and harvest system for anchorage-dependent cells

Also Published As

Publication number Publication date
US8343742B2 (en) 2013-01-01
EP1781347A1 (de) 2007-05-09
EP1781347A4 (de) 2010-07-21
WO2006011855A8 (en) 2006-04-06
WO2006011855A1 (en) 2006-02-02
US20060019362A1 (en) 2006-01-26
US20100136649A1 (en) 2010-06-03
US7704714B2 (en) 2010-04-27
EP1781347B1 (de) 2011-12-07

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