ATE536348T1 - Verfahren zur herstellung von benzothiazepinen aus gamma-aminoalkylbenzolen - Google Patents
Verfahren zur herstellung von benzothiazepinen aus gamma-aminoalkylbenzolenInfo
- Publication number
- ATE536348T1 ATE536348T1 AT09718412T AT09718412T ATE536348T1 AT E536348 T1 ATE536348 T1 AT E536348T1 AT 09718412 T AT09718412 T AT 09718412T AT 09718412 T AT09718412 T AT 09718412T AT E536348 T1 ATE536348 T1 AT E536348T1
- Authority
- AT
- Austria
- Prior art keywords
- aminoalkylbenezenes
- benzothiazepines
- gamma
- producing
- producing benzothiazepines
- Prior art date
Links
- 150000007657 benzothiazepines Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3319708P | 2008-03-03 | 2008-03-03 | |
| PCT/US2009/035863 WO2009111463A1 (en) | 2008-03-03 | 2009-03-03 | Process for preparing benzothiazepines from gamma-aminoalkylbenzenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE536348T1 true ATE536348T1 (de) | 2011-12-15 |
Family
ID=40585577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09718412T ATE536348T1 (de) | 2008-03-03 | 2009-03-03 | Verfahren zur herstellung von benzothiazepinen aus gamma-aminoalkylbenzolen |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8618282B2 (de) |
| EP (1) | EP2250159B1 (de) |
| JP (1) | JP5458025B2 (de) |
| KR (1) | KR101260859B1 (de) |
| CN (1) | CN101977902B (de) |
| AR (1) | AR071282A1 (de) |
| AT (1) | ATE536348T1 (de) |
| AU (1) | AU2009221969B2 (de) |
| BR (1) | BRPI0908570A2 (de) |
| CA (1) | CA2717523C (de) |
| CY (1) | CY1112538T1 (de) |
| DK (1) | DK2250159T3 (de) |
| EA (2) | EA020602B9 (de) |
| ES (1) | ES2378871T3 (de) |
| HR (1) | HRP20120182T1 (de) |
| IL (1) | IL207651A (de) |
| ME (1) | ME01989B (de) |
| MX (1) | MX2010009608A (de) |
| NZ (1) | NZ587767A (de) |
| PL (1) | PL2250159T3 (de) |
| PT (1) | PT2250159E (de) |
| RS (1) | RS52172B (de) |
| SI (1) | SI2250159T1 (de) |
| WO (1) | WO2009111463A1 (de) |
| ZA (1) | ZA201005956B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8710045B2 (en) * | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
| EP2708535A1 (de) | 2012-05-11 | 2014-03-19 | Les Laboratoires Servier | Mittel zur Behandlung von Erkrankungen durch Modulation von Ryanodin-Rezeptoren |
| CN108530385B (zh) * | 2018-07-16 | 2019-10-01 | 青岛科技大学 | 一种1,3-苯并硫氮杂*类化合物的制备方法 |
| KR20230129267A (ko) | 2021-01-08 | 2023-09-07 | 암고 파마, 인크. | 리아노딘 수용체 조정제의 결정질 형태 및 그의 용도 |
| WO2022246114A2 (en) | 2021-05-20 | 2022-11-24 | Armgo Pharma, Inc. | Pharmaceutical compositions comprising a ryanodine receptor modulator and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2703408B2 (ja) * | 1990-12-28 | 1998-01-26 | 麒麟麦酒株式会社 | １，４‐ベンゾチアゼピン誘導体 |
| KR100313649B1 (ko) | 1992-11-09 | 2002-02-28 | 더 부츠 캄파니 피엘씨 | 신경계질환치료제로서유용한1,4-벤조티아제핀,이의제조방법및이를포함하는약제학적조성물 |
| IL108634A0 (en) * | 1993-02-15 | 1994-05-30 | Wellcome Found | Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them |
| GB9616279D0 (en) * | 1996-08-02 | 1996-09-11 | Knoll Ag | Chemical process |
| US7718644B2 (en) * | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
| US20040229781A1 (en) * | 2000-05-10 | 2004-11-18 | Marks Andrew Robert | Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias |
| US8022058B2 (en) * | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US7879840B2 (en) * | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US7704990B2 (en) * | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
-
2009
- 2009-03-03 KR KR1020107022040A patent/KR101260859B1/ko active Active
- 2009-03-03 CA CA2717523A patent/CA2717523C/en active Active
- 2009-03-03 EA EA201001406A patent/EA020602B9/ru not_active IP Right Cessation
- 2009-03-03 WO PCT/US2009/035863 patent/WO2009111463A1/en not_active Ceased
- 2009-03-03 BR BRPI0908570-0A patent/BRPI0908570A2/pt not_active Application Discontinuation
- 2009-03-03 PT PT09718412T patent/PT2250159E/pt unknown
- 2009-03-03 PL PL09718412T patent/PL2250159T3/pl unknown
- 2009-03-03 EP EP09718412A patent/EP2250159B1/de active Active
- 2009-03-03 RS RS20120066A patent/RS52172B/sr unknown
- 2009-03-03 ME MEP-2012-160A patent/ME01989B/me unknown
- 2009-03-03 AT AT09718412T patent/ATE536348T1/de active
- 2009-03-03 HR HR20120182T patent/HRP20120182T1/hr unknown
- 2009-03-03 MX MX2010009608A patent/MX2010009608A/es active IP Right Grant
- 2009-03-03 CN CN2009801079022A patent/CN101977902B/zh active Active
- 2009-03-03 US US12/397,212 patent/US8618282B2/en active Active
- 2009-03-03 JP JP2010549813A patent/JP5458025B2/ja active Active
- 2009-03-03 NZ NZ587767A patent/NZ587767A/en unknown
- 2009-03-03 AU AU2009221969A patent/AU2009221969B2/en active Active
- 2009-03-03 DK DK09718412.1T patent/DK2250159T3/da active
- 2009-03-03 EA EA201400570A patent/EA028108B1/ru not_active IP Right Cessation
- 2009-03-03 SI SI200930194T patent/SI2250159T1/sl unknown
- 2009-03-03 ES ES09718412T patent/ES2378871T3/es active Active
- 2009-03-04 AR ARP090100751A patent/AR071282A1/es active IP Right Grant
-
2010
- 2010-08-17 IL IL207651A patent/IL207651A/en active IP Right Grant
- 2010-08-20 ZA ZA2010/05956A patent/ZA201005956B/en unknown
-
2012
- 2012-02-21 CY CY20121100178T patent/CY1112538T1/el unknown
-
2013
- 2013-12-23 US US14/138,893 patent/US9573914B2/en active Active
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