ATE538132T1 - Chimäre chemokinrezeptorpolypeptide - Google Patents

Chimäre chemokinrezeptorpolypeptide

Info

Publication number
ATE538132T1
ATE538132T1 AT04819114T AT04819114T ATE538132T1 AT E538132 T1 ATE538132 T1 AT E538132T1 AT 04819114 T AT04819114 T AT 04819114T AT 04819114 T AT04819114 T AT 04819114T AT E538132 T1 ATE538132 T1 AT E538132T1
Authority
AT
Austria
Prior art keywords
chemokine receptor
chimeric
receptor polypeptides
chimeric chemokine
terminus
Prior art date
Application number
AT04819114T
Other languages
English (en)
Inventor
Joseph E Dinchuk
Paul Davies
Qihong Zhao
Percy Carter
Kimberly Solomon
Peggy Ann Scherle
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE538132T1 publication Critical patent/ATE538132T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04819114T 2003-11-13 2004-11-12 Chimäre chemokinrezeptorpolypeptide ATE538132T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51960503P 2003-11-13 2003-11-13
PCT/US2004/037892 WO2005049799A2 (en) 2003-11-13 2004-11-12 Chimeric chemokine receptor polypeptides

Publications (1)

Publication Number Publication Date
ATE538132T1 true ATE538132T1 (de) 2012-01-15

Family

ID=34619366

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04819114T ATE538132T1 (de) 2003-11-13 2004-11-12 Chimäre chemokinrezeptorpolypeptide

Country Status (5)

Country Link
US (1) US7259000B2 (de)
EP (1) EP1692161B1 (de)
AT (1) ATE538132T1 (de)
ES (1) ES2377649T3 (de)
WO (1) WO2005049799A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010521413A (ja) 2006-03-16 2010-06-24 プロタゴニスツ リミテッド 免疫系機能を改変するためのサイトカインとサイトカイン受容体の組合せ
US20110044945A1 (en) * 2007-02-08 2011-02-24 Rappaport Family Institute For Research In The Medical Sciences Agents for the treatment of multiple sclerosis and methods of using same
US20100249022A1 (en) * 2007-05-18 2010-09-30 University Of Massachusetts Strategy for cloning and expressing the extracellular domains of receptors as soluble proteins
WO2008146272A2 (en) * 2007-05-31 2008-12-04 Rappaport Family Institute For Research In The Medical Sciences Compositions and methods for treating cxcr6/cxcl16 associated diseases
WO2008149354A2 (en) 2007-06-04 2008-12-11 Rappaport Family Institute For Research In The Medical Sciences Agents for the treatment of inflammatory diseases and methods of using same
WO2010103517A1 (en) 2009-03-12 2010-09-16 Rappaport Family Institute For Research In The Medical Sciences Soluble compositions for the treatment of cxcr3-ligand associated diseases
AU2018223211B2 (en) * 2017-02-21 2025-02-27 Adelaide university T cells expressing chemokine receptors for treating cancer
CN108250290B (zh) * 2018-02-23 2024-03-12 上海捌加壹医药科技有限公司 Ccr4的n端重组蛋白及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3532570B2 (ja) * 1994-01-13 2004-05-31 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 哺乳類単球化学誘引物質タンパク質レセプター
TW200409630A (en) * 2002-09-12 2004-06-16 Bristol Myers Squibb Co N-ureidoalkyl-piperidines as modulators of chemokine receptor activity

Also Published As

Publication number Publication date
US7259000B2 (en) 2007-08-21
WO2005049799A3 (en) 2006-01-05
EP1692161A4 (de) 2008-10-15
EP1692161A2 (de) 2006-08-23
ES2377649T3 (es) 2012-03-29
US20050123972A1 (en) 2005-06-09
EP1692161B1 (de) 2011-12-21
WO2005049799A2 (en) 2005-06-02

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