ATE538201T1 - Kcnb: ein kaliumkanalprotein - Google Patents

Kcnb: ein kaliumkanalprotein

Info

Publication number
ATE538201T1
ATE538201T1 AT01924111T AT01924111T ATE538201T1 AT E538201 T1 ATE538201 T1 AT E538201T1 AT 01924111 T AT01924111 T AT 01924111T AT 01924111 T AT01924111 T AT 01924111T AT E538201 T1 ATE538201 T1 AT E538201T1
Authority
AT
Austria
Prior art keywords
kcnb
potassium channel
channel protein
activity
modulate
Prior art date
Application number
AT01924111T
Other languages
English (en)
Inventor
David Mu
Scott Powers
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE538201T1 publication Critical patent/ATE538201T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Obesity (AREA)
AT01924111T 2000-03-03 2001-03-02 Kcnb: ein kaliumkanalprotein ATE538201T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18691500P 2000-03-03 2000-03-03
PCT/US2001/006801 WO2001066741A2 (en) 2000-03-03 2001-03-02 Kcnb: a novel potassium channel protein

Publications (1)

Publication Number Publication Date
ATE538201T1 true ATE538201T1 (de) 2012-01-15

Family

ID=22686808

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01924111T ATE538201T1 (de) 2000-03-03 2001-03-02 Kcnb: ein kaliumkanalprotein

Country Status (12)

Country Link
US (2) US7462465B2 (de)
EP (1) EP1266003B1 (de)
JP (2) JP2004500825A (de)
CN (1) CN1426468A (de)
AT (1) ATE538201T1 (de)
AU (2) AU2001250794B2 (de)
CA (1) CA2401906C (de)
ES (1) ES2378417T3 (de)
IL (2) IL151564A0 (de)
NZ (1) NZ521205A (de)
WO (1) WO2001066741A2 (de)
ZA (1) ZA200206999B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1471922A4 (de) * 2001-12-31 2007-03-07 Algos Therapeutics Inc Verfahren und materialien zur modulation von task-3
WO2005052586A2 (en) * 2003-11-27 2005-06-09 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with potassium channel, subfamily k, member 3 (kcnk3)
WO2005075510A1 (en) * 2004-02-04 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with potassium channel, subfamily k, member 9 (kcnk9)
US12416024B2 (en) 2018-03-29 2025-09-16 Transworld Technologies Inc. Biologically enhanced oil recovery methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2744730B1 (fr) 1996-02-08 1998-04-17 Centre Nat Rech Scient Nouvelle famille de canaux potassium de mammifere, leur clonage et leur utilisation notamment pour le criblage de drogues
WO1999037762A1 (en) 1998-01-27 1999-07-29 Smithkline Beecham Plc Trek-1 like two pore potassium channel
EP1090118A2 (de) * 1998-06-26 2001-04-11 Incyte Pharmaceuticals, Inc. Menschliche proteine mit signalpeptid
ATE394486T1 (de) 1998-11-09 2008-05-15 Centre Nat Rech Scient Neue familie von säugetier-kaliumkanälen, ihre klonierung und ihre verwendung, besonders für das drogenscreening
JP2002542765A (ja) * 1999-03-05 2002-12-17 スミスクライン ビーチャム パブリック リミテッド カンパニー 新規化合物
US20020137202A1 (en) * 1999-12-21 2002-09-26 Catherine Burgess Novel proteins and nucleic acids encoding same
AU3087801A (en) 2000-02-04 2001-08-14 Molecular Dynamics Inc Human genome-derived single exon nucleic acid probes useful for analysis of geneexpression in human breast and hbl 100 cells
WO2001077174A2 (en) 2000-04-06 2001-10-18 Incyte Genomics, Inc. Human transporters and ion channels
WO2002026983A2 (en) 2000-09-25 2002-04-04 Millennium Pharmaceuticals, Inc. 56115, a novel human twik potassium channel and uses therefor

Also Published As

Publication number Publication date
ZA200206999B (en) 2004-05-31
AU2001250794B2 (en) 2006-03-02
NZ521205A (en) 2005-09-30
EP1266003A2 (de) 2002-12-18
CA2401906A1 (en) 2001-09-13
AU5079401A (en) 2001-09-17
WO2001066741A9 (en) 2003-03-06
CN1426468A (zh) 2003-06-25
WO2001066741A2 (en) 2001-09-13
ES2378417T3 (es) 2012-04-12
US7462465B2 (en) 2008-12-09
EP1266003B1 (de) 2011-12-21
JP2004500825A (ja) 2004-01-15
CA2401906C (en) 2011-07-19
WO2001066741A3 (en) 2002-04-04
IL151564A0 (en) 2003-04-10
JP2011115169A (ja) 2011-06-16
US20020102676A1 (en) 2002-08-01
IL151564A (en) 2008-11-03
US20080234470A1 (en) 2008-09-25

Similar Documents

Publication Publication Date Title
AU2085502A (en) Diagnosis and treatment of disease
DE60330842D1 (de) Für den nachweis von nukleinsäuren kompetente biologische rohderivate
DE60322880D1 (de) Einfache katalytische dna-biosensoren für ionen auf grundlage von farbveränderungen
DE60023936D1 (de) Methoden zur verwendung von randomisierten zinkfingerprotein-bibliotheken zur identifizierung von genfunktionen
SE0003286D0 (sv) Method and kit for human identification
DE69735445D1 (de) Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung
EA200200094A1 (ru) Нуклеиновые кислоты-лиганды тенасцина-с
ATE439441T1 (de) Veränderte, fluoreszierende proteine
ATE286984T1 (de) Methode und testsatz zur detektion von schistosomiasis mittels polymerasekettenreaktion
HUP0100668A2 (hu) Virulenciával kapcsolatos nukleinsavszekvenciák és alkalmazásuk
CU23302A1 (es) Medio de cultivo selectivo para el aislamiento y detecciã"n de especies del gã0/00nero streptococcus
TR200501541T2 (tr) Leu-hirudinin e.coli ile kültür ortamında ayrışarak üretilmesinin sinyal sekansları
ATE389881T1 (de) Detektion von kleinen molekülen mit piezo- elektrischem sensor
ATE538201T1 (de) Kcnb: ein kaliumkanalprotein
ATE389018T1 (de) Cx3c chemokin-gene von säugetieren
ATE288589T1 (de) Verfahren zur analyse von proteinen
ATE456666T1 (de) Verfahren zur auswertung von ribonukleotidsequenzen
DE69734586D1 (de) Retinoid-metabolisierendes protein
DE60121547D1 (de) Electrochemisches verfahren zum nachweis von nukleinsäuren
BR0108767A (pt) Adenilciclase recombinante, polinucleotìdeo, vetor, processos para a detecção de atividade proteolìtica de uma molécula e da resistência a um inibidor, de uma molécula com atividade proteolìtica e de identificação de moléculas com atividade proteolìtica sìtio-especìfica, kit de diagnóstico, utilização de uma adenilciclase, e, cepa bacteriana
ATE409742T1 (de) Von bacillus cereus produzierte cereulid-synthase,diese codierendes gen und verfahren zum nachweis von cereulid
WO2001031009A3 (en) Chandra: a th1-specific gene
WO2002081691A3 (en) Abcg5 and abcg8: compositions and methods of use
DE602006004966D1 (de) Intrinsic-faktor vom schwein
DE50113417D1 (de) Zellbindende nukleinsäuremoleküle (aptamere)