ATE539165T1 - Verfahren zum nachweis von beta-lactamase - Google Patents

Verfahren zum nachweis von beta-lactamase

Info

Publication number
ATE539165T1
ATE539165T1 AT08840533T AT08840533T ATE539165T1 AT E539165 T1 ATE539165 T1 AT E539165T1 AT 08840533 T AT08840533 T AT 08840533T AT 08840533 T AT08840533 T AT 08840533T AT E539165 T1 ATE539165 T1 AT E539165T1
Authority
AT
Austria
Prior art keywords
beta
lactamases
lactamase
methods
detecting beta
Prior art date
Application number
AT08840533T
Other languages
English (en)
Inventor
Mei Yang-Woytowitz
Charles Yu
Timothy Wiles
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Application granted granted Critical
Publication of ATE539165T1 publication Critical patent/ATE539165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT08840533T 2007-10-19 2008-10-20 Verfahren zum nachweis von beta-lactamase ATE539165T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98115607P 2007-10-19 2007-10-19
PCT/US2008/011934 WO2009051838A1 (en) 2007-10-19 2008-10-20 Methods and compositions for the detection of beta-lactamases

Publications (1)

Publication Number Publication Date
ATE539165T1 true ATE539165T1 (de) 2012-01-15

Family

ID=40039682

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08840533T ATE539165T1 (de) 2007-10-19 2008-10-20 Verfahren zum nachweis von beta-lactamase

Country Status (5)

Country Link
US (7) US8097434B2 (de)
EP (1) EP2207893B1 (de)
JP (5) JP5628677B2 (de)
AT (1) ATE539165T1 (de)
WO (1) WO2009051838A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5628677B2 (ja) 2007-10-19 2014-11-19 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company ベータ−ラクタマーゼの検出のための方法および組成物
US9834807B2 (en) 2008-10-20 2017-12-05 Becton, Dickinson And Company Compositions for the detection of intracellular bacterial targets and other intracellular micororganism targets
FR2956866B1 (fr) * 2010-03-01 2014-01-10 Bio Rad Pasteur Procede de detection en milieu liquide de bacteries resistantes aux cephalosporines de troisieme generation
FR2956868B1 (fr) * 2010-03-01 2014-01-10 Bio Rad Pasteur Procede rapide de detection d'enzymes et de microorganismes
EP2723884B2 (de) 2011-06-22 2024-09-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Verfahren für den nachweis von carbapenemase-produzierenden bakterien in einer probe
WO2013053953A1 (en) * 2011-10-14 2013-04-18 Université de Liège Method for measuring beta-lactam antibiotics
ES2621823T3 (es) * 2011-11-18 2017-07-05 Inserm - Institut National De La Santé Et De La Recherche Médicale Procedimiento para detectar la presencia de bacterias productoras de ß-lactamasa de amplio espectro en una muestra
FR2993900B1 (fr) * 2012-07-27 2016-03-25 Biomerieux Sa Procede de detection de bacteries productrices de carbapenemases de type oxa-48
KR101389696B1 (ko) 2012-08-29 2014-05-07 한림대학교 산학협력단 β-락타메이즈 저해제를 이용한 액체배지 미량희석법으로 KPC 및 MBL 생산을 탐지하는 방법
EP3052642A2 (de) 2013-09-30 2016-08-10 AdvanDx, Inc. Suszeptibilitätstest für eine antimikrobielle verbindung
EP2862941A1 (de) * 2013-10-17 2015-04-22 VI-Diagnostics GmbH Verfahren zur quantitativen Bestimmung der beta-Lactamase-Aktivität in Körperflüssigkeiten und Bakteriensuspensionen
MX2016013462A (es) * 2014-04-15 2017-06-21 Cellex Inc Metodos y dispositivos para deteccion de resistencia a un inhibidor de enzima.
JP2016010399A (ja) * 2014-06-03 2016-01-21 日水製薬株式会社 カルバペネマーゼ産生耐性菌検出用組成物
GB201417529D0 (en) 2014-10-03 2014-11-19 Isis Innovation Beta lactamase inhibitors
US9879328B2 (en) * 2014-11-21 2018-01-30 GeneWeave Biosciences, Inc. Mechanisms of antimicrobial susceptibility
FR3034523B1 (fr) 2015-04-03 2020-01-17 Universite De Bourgogne Nouvelle methode pour detecter la presence de bacteries productrices de beta-lactamases.
GB201521899D0 (en) * 2015-12-11 2016-01-27 Mast Group Ltd Extraction discs
JP2019519235A (ja) * 2016-06-27 2019-07-11 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 細菌における抗微生物剤耐性を検出するための組成物、方法、システムおよび/またはキット
US20200131558A1 (en) * 2017-04-21 2020-04-30 Colorado State University Research Foundation Paper-based assay for antimicrobial resistance
GB201712671D0 (en) * 2017-08-07 2017-09-20 Mast Group Ltd Chromogenic Carbapenemase detection method
AU2018318138A1 (en) * 2017-08-14 2020-03-19 University Of Louisville Research Foundation, Inc. Methods and kits for detecting antibiotic-inactivating factors
US11268960B2 (en) 2018-01-10 2022-03-08 SeLux Diagnostics, Inc. Assays for improving automated antimicrobial susceptibility testing accuracy
WO2020018462A1 (en) 2018-07-16 2020-01-23 Brown University A chromogenic beta-lactamase substrate
US11291997B2 (en) 2018-08-02 2022-04-05 Colorado State University Research Foundation Rotary manifold for paper-based immunoassays
US12195755B2 (en) 2019-05-20 2025-01-14 Brown University Placental lipid bilayer for cell-free molecular interaction studies
US20200376094A1 (en) * 2019-05-28 2020-12-03 Aybar Ecotechnologies Corp. Wide-spectrum antibacterial pharmaceutical formulations comprising lysozyme and methods of using the same
WO2021007492A1 (en) * 2019-07-10 2021-01-14 SeLux Diagnostics, Inc. Assays for improving automated antimicrobial susceptibility testing accuracy
WO2021087008A1 (en) 2019-10-28 2021-05-06 Brown University Bacterial beta-lactamase responsive hydrogels
CN111041067A (zh) * 2019-12-20 2020-04-21 赛莱克斯(深圳)科技有限公司 一种检测β-内酰胺酶及其抑制复合剂耐药性的试剂与方法

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3019451A1 (de) 1980-05-21 1981-11-26 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und reagens zur bestimmung von (beta) -lactamasen
EP0059645B1 (de) 1981-03-03 1986-06-04 National Research Development Corporation Verfahren und Kit zur Feststellung von Beta-Lactamasen
GB2093994B (en) 1981-03-03 1984-10-24 Nat Res Dev Idendification of beta-lactamase
US4740459A (en) 1984-08-06 1988-04-26 Washington Research Foundation Fluorescence assay for microbial beta-lactamase
US4965193A (en) 1984-08-06 1990-10-23 Washington Research Foundation Detection of microbial beta-lactamase
ATE68524T1 (de) 1985-07-09 1991-11-15 Quadrant Bioresources Ltd Beschuetzung von proteinen und aehnlichem.
US4712310A (en) 1986-09-15 1987-12-15 E. I. Du Pont De Nemours And Company Co-spray technique
EP0538447B1 (de) 1991-05-06 1997-05-28 Dade MicroScan Inc. Schneller auswahltest für induzierbare beta-laktamase
US5776563A (en) 1991-08-19 1998-07-07 Abaxis, Inc. Dried chemical compositions
JP3082374B2 (ja) * 1991-11-13 2000-08-28 富士レビオ株式会社 1,2−ジオキセタン誘導体の安定化剤
US5338843A (en) 1992-01-30 1994-08-16 Becton, Dickinson And Company Fluorogenic and chromogenic β-lactamase substrates
JP3442784B2 (ja) 1993-11-23 2003-09-02 ジェネンテク,インコーポレイテッド キナーゼ受容体活性化検定法
US5741657A (en) 1995-03-20 1998-04-21 The Regents Of The University Of California Fluorogenic substrates for β-lactamase and methods of use
US7427680B2 (en) 2001-01-12 2008-09-23 The Regents Of The University Of California Fluorogenic substrates for BETA-lactamase gene expression
WO1997003348A1 (en) 1995-07-13 1997-01-30 Immunological Associates Of Denver Self-contained device integrating nucleic acid extraction, amplification and detection
US5955604A (en) 1996-10-15 1999-09-21 The Regents Of The University Of California Substrates for β-lactamase and uses thereof
USD421498S (en) 1997-05-23 2000-03-07 Becton, Dickinson And Company Microbiological test panel
US5922593A (en) 1997-05-23 1999-07-13 Becton, Dickinson And Company Microbiological test panel and method therefor
BR9809154B1 (pt) 1997-05-23 2012-09-04 aparelho e sistema de teste microbiológico diagnóstico.
US6075014A (en) * 1997-06-13 2000-06-13 Northwestern University Inhibitors of β-lactamases and uses therefor
US5995604A (en) * 1997-06-20 1999-11-30 Nortel Networks Corporation Method of preventing fraudulent toll calls by key system users
US6284461B1 (en) * 1998-04-28 2001-09-04 Aurora Biosciences Corporation Use of inhibitors in reporter assays
JP4003993B2 (ja) * 1998-07-17 2007-11-07 富士フイルム株式会社 乾式分析要素の製造方法及び乾式分析要素
US6242223B1 (en) * 1998-09-28 2001-06-05 Creighton University Primers for use in detecting beta-lactamases
WO2001083492A1 (en) 2000-05-02 2001-11-08 Newbiotics, Inc. Improved beta-lactam antibiotics
US6849422B1 (en) * 2000-05-31 2005-02-01 Becton, Dickinson And Company System and method for analyzing antibiotic susceptibility of biological samples using redox and turbidity measurments to ascertain minimum inhibitory concentrations (MICs)
AU9025601A (en) * 2000-09-22 2002-04-02 Zenyaku Kogyo Kabushiki Kaisya Cephem compounds and esbl-detecting reagents containing the same
ES2180416B1 (es) 2001-03-12 2004-06-01 BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen.
US7109294B2 (en) 2001-09-18 2006-09-19 Trustees Of Dartmouth College Bacterial glycosyltransferase polypeptides involved in antibiotic resistance
EP1440082B1 (de) 2001-10-22 2011-09-28 Dompé S.P.A. Verfahren durch gebrauch von überkritischen flüssigkeiten: herstellung von proteinmikropartikeln und ihre stabilisierung
EP1499741A4 (de) 2002-03-13 2006-07-05 Univ Creighton Vorrichtung und verfahren zum nachweis antibiotisch-inaktivierender enzyme
US7291480B2 (en) 2002-03-13 2007-11-06 Black Jennifer A Device and method for detecting antibiotic-inactivating enzymes
JP2004016694A (ja) * 2002-06-20 2004-01-22 Matsushita Electric Ind Co Ltd 電動調理機
AU2003252136A1 (en) 2002-07-24 2004-02-09 Ptc Therapeutics, Inc. METHODS FOR IDENTIFYING SMALL MOLEDULES THAT MODULATE PREMATURE TRANSLATION TERMINATION AND NONSENSE MEDIATED mRNA DECAY
ATE425261T1 (de) * 2002-10-29 2009-03-15 Showa Pharm Chem Ind Reagenzzusammensetzung, kit und verfahren zur unterscheidung von beta-lactamasen
JP2004166694A (ja) * 2002-10-29 2004-06-17 Showa Yakuhin Kako Kk β−ラクタマーゼ検出試薬組成物、検出キット及び検出方法
US20040241779A1 (en) 2003-02-24 2004-12-02 Piasio Roger N. Dry chemistry, lateral flow-reconstituted chromatographic enzyme-driven assays
DE602004024769D1 (de) 2003-03-17 2010-02-04 Charles River Lab Inc Methoden und zusammensetzungen für den nachweis mikrobieller verunreinigungen
RU2240136C1 (ru) 2003-04-10 2004-11-20 Государственное учреждение "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н.Габричевского МЗ РФ" Композиция, содержащая иммуноглобулины и целевые добавки
SE0302840D0 (sv) 2003-10-29 2003-10-29 Affibody Ab Detection method
WO2005071096A2 (en) 2004-01-21 2005-08-04 Molecular Probes, Inc. Derivatives of cephalosporin and clavulanic acid for detecting beta-lacamase in a sample
WO2006043558A1 (ja) * 2004-10-19 2006-04-27 Japan Health Sciences Foundation 細菌が産生するβ-ラクタマーゼのクラスを識別する方法
WO2006119280A2 (en) 2005-05-03 2006-11-09 Handylab, Inc. Lyophilized pellets
KR101381331B1 (ko) 2005-05-09 2014-04-04 테라노스, 인코포레이티드 현장진료 유체 시스템 및 그 용도
JP4874008B2 (ja) 2005-07-01 2012-02-08 水ing株式会社 細菌を検出する方法およびその装置
WO2008095222A1 (en) * 2007-02-05 2008-08-14 Panbio Limited Homogeneous in vitro fec assays and components
AU2008263883B2 (en) 2007-06-15 2014-03-13 Basf Se Method for producing difluoromethyl-substituted pyrazole compounds
JP5628677B2 (ja) 2007-10-19 2014-11-19 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company ベータ−ラクタマーゼの検出のための方法および組成物
US20100209927A1 (en) 2007-11-06 2010-08-19 Menon Vinod P Processing device tablet
WO2009114921A1 (en) * 2008-03-17 2009-09-24 Dmitrienko Gary I INHIBITORS OF CLASS B AND CLASS D β-LACTAMASES
WO2010004778A1 (ja) 2008-07-08 2010-01-14 コニカミノルタエムジー株式会社 平版印刷版材料用の現像液および平版印刷版材料
US9834807B2 (en) 2008-10-20 2017-12-05 Becton, Dickinson And Company Compositions for the detection of intracellular bacterial targets and other intracellular micororganism targets
HUE062700T2 (hu) * 2010-08-19 2023-11-28 Univ Erasmus Med Ct Rotterdam Eljárások antibiotikum-rezisztencia meghatározására mikroorganizmusokban
FR3024465B1 (fr) * 2014-07-30 2018-03-23 Biomerieux Caracterisation de micro-organismes par maldi-tof

Also Published As

Publication number Publication date
JP5628677B2 (ja) 2014-11-19
US9085794B2 (en) 2015-07-21
JP2015002749A (ja) 2015-01-08
EP2207893B1 (de) 2011-12-28
US20090117601A1 (en) 2009-05-07
US20180334701A1 (en) 2018-11-22
JP2011500057A (ja) 2011-01-06
US8097434B2 (en) 2012-01-17
EP2207893A1 (de) 2010-07-21
JP2018029607A (ja) 2018-03-01
JP6220759B2 (ja) 2017-10-25
WO2009051838A1 (en) 2009-04-23
JP6863955B2 (ja) 2021-04-21
US10704079B2 (en) 2020-07-07
JP2021104043A (ja) 2021-07-26
US20240018567A1 (en) 2024-01-18
US11572579B2 (en) 2023-02-07
JP7234280B2 (ja) 2023-03-07
US8389234B2 (en) 2013-03-05
US20120077215A1 (en) 2012-03-29
JP2019022528A (ja) 2019-02-14
US20160138076A1 (en) 2016-05-19
US20210155969A1 (en) 2021-05-27
JP6438099B2 (ja) 2018-12-12
US9902989B2 (en) 2018-02-27
US20140080164A1 (en) 2014-03-20

Similar Documents

Publication Publication Date Title
Wang et al. Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Chinese hospitals
TW200616578A (en) Fluid handling devices
ATE431427T1 (de) Verbessertes verfahren zum nachweis von atp
ATE522627T1 (de) Verfahren zur herstellung von nukleinsäuresonden
EP2212700B8 (de) Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex
ATE548467T1 (de) Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände
ATE518008T1 (de) System zum zählen von bakterien und zur bestimmung von deren anfälligkeit gegenüber antibiotika
MA35212B1 (fr) Essai de la lysyl oxydase de type 2 et ses procédés d'utilisation
DE502006005886D1 (de) Verfahren und vorrichtung zur bewertung von fügestellen von werkstücken
GB201014028D0 (en) In-situ reagent
DE60124975D1 (de) Automatischer apparat zum messen von wassertoxizität
ATE443775T1 (de) Hif-prolylhydroxylase-aktivitätstest
DE602007000378D1 (de) Verfahren und Vorrichtung zur Überprüfung der Integrität eines Wartungszusammenhangs sowie Verfahren und Vorrichtung zum Einfügen eines Wartungsendpunktes
WO2007082181A3 (en) Methods of modulating cell surface receptors to prevent or reduce inflammation
WO2006031936A3 (en) Device and method for detecting antibiotic-inactivating enzymes
ATE347105T1 (de) Verfahren, assay und kit zur quantifizierung von hiv-proteasehemmer
GB0600916D0 (en) detecting and predicting pre-eclampsia
TW200641137A (en) A method for quantifying cholesterol of remnant-like particles lipoprotein, reagent and kit
SG179447A1 (en) The quantitative determination of risedronate in urine by spe-lc-ms-ms
WO2009158119A3 (en) Compositions, kits and related methods for the detection and/or monitoring of salmonella
TW200508605A (en) Analysis method
BRPI0414283A (pt) métodos, composições e kits para a concentração e detecção de microorganismos
WO2008038129A3 (en) Microsensor for detection of d-amino-acids
TW200639404A (en) Method of assessing the effectiveness of a treatment regimen
DE502004007244D1 (de) Verfahren zum spezifischen schnellnachweis getr nkesch dlicher mikroorganismen