ATE539165T1 - Verfahren zum nachweis von beta-lactamase - Google Patents
Verfahren zum nachweis von beta-lactamaseInfo
- Publication number
- ATE539165T1 ATE539165T1 AT08840533T AT08840533T ATE539165T1 AT E539165 T1 ATE539165 T1 AT E539165T1 AT 08840533 T AT08840533 T AT 08840533T AT 08840533 T AT08840533 T AT 08840533T AT E539165 T1 ATE539165 T1 AT E539165T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- lactamases
- lactamase
- methods
- detecting beta
- Prior art date
Links
- 102000006635 beta-lactamase Human genes 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 108090000204 Dipeptidase 1 Proteins 0.000 title 1
- 108020004256 Beta-lactamase Proteins 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 2
- 108010056874 AmpC beta-lactamases Proteins 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 108010068385 carbapenemase Proteins 0.000 abstract 1
- 102000020235 metallo-beta-lactamase Human genes 0.000 abstract 1
- 108060004734 metallo-beta-lactamase Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98115607P | 2007-10-19 | 2007-10-19 | |
| PCT/US2008/011934 WO2009051838A1 (en) | 2007-10-19 | 2008-10-20 | Methods and compositions for the detection of beta-lactamases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE539165T1 true ATE539165T1 (de) | 2012-01-15 |
Family
ID=40039682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08840533T ATE539165T1 (de) | 2007-10-19 | 2008-10-20 | Verfahren zum nachweis von beta-lactamase |
Country Status (5)
| Country | Link |
|---|---|
| US (7) | US8097434B2 (de) |
| EP (1) | EP2207893B1 (de) |
| JP (5) | JP5628677B2 (de) |
| AT (1) | ATE539165T1 (de) |
| WO (1) | WO2009051838A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8097434B2 (en) * | 2007-10-19 | 2012-01-17 | Becton, Dickinson And Company | Methods for the detection of beta-lactamases |
| WO2010047778A1 (en) | 2008-10-20 | 2010-04-29 | Becton Dickinson And Company | Compositions for the detection of intracellular bacterial targets and other intracellular microorganism targets |
| FR2956866B1 (fr) * | 2010-03-01 | 2014-01-10 | Bio Rad Pasteur | Procede de detection en milieu liquide de bacteries resistantes aux cephalosporines de troisieme generation |
| FR2956868B1 (fr) | 2010-03-01 | 2014-01-10 | Bio Rad Pasteur | Procede rapide de detection d'enzymes et de microorganismes |
| CA2837246C (en) * | 2011-06-22 | 2020-08-18 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Method for detecting the presence of carbapenemase-producing bacteria in a sample |
| WO2013053953A1 (en) * | 2011-10-14 | 2013-04-18 | Université de Liège | Method for measuring beta-lactam antibiotics |
| ES2621823T3 (es) * | 2011-11-18 | 2017-07-05 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Procedimiento para detectar la presencia de bacterias productoras de ß-lactamasa de amplio espectro en una muestra |
| FR2993900B1 (fr) * | 2012-07-27 | 2016-03-25 | Biomerieux Sa | Procede de detection de bacteries productrices de carbapenemases de type oxa-48 |
| KR101389696B1 (ko) | 2012-08-29 | 2014-05-07 | 한림대학교 산학협력단 | β-락타메이즈 저해제를 이용한 액체배지 미량희석법으로 ＫＰＣ 및 ＭＢＬ 생산을 탐지하는 방법 |
| EP3052642A2 (de) | 2013-09-30 | 2016-08-10 | AdvanDx, Inc. | Suszeptibilitätstest für eine antimikrobielle verbindung |
| EP2862941A1 (de) * | 2013-10-17 | 2015-04-22 | VI-Diagnostics GmbH | Verfahren zur quantitativen Bestimmung der beta-Lactamase-Aktivität in Körperflüssigkeiten und Bakteriensuspensionen |
| WO2015160712A1 (en) * | 2014-04-15 | 2015-10-22 | Cellex, Incorporated | Methods and devices for detection of resistance to an enzyme inhibitor |
| JP2016010399A (ja) * | 2014-06-03 | 2016-01-21 | 日水製薬株式会社 | カルバペネマーゼ産生耐性菌検出用組成物 |
| GB201417529D0 (en) | 2014-10-03 | 2014-11-19 | Isis Innovation | Beta lactamase inhibitors |
| US9879328B2 (en) * | 2014-11-21 | 2018-01-30 | GeneWeave Biosciences, Inc. | Mechanisms of antimicrobial susceptibility |
| FR3034523B1 (fr) * | 2015-04-03 | 2020-01-17 | Universite De Bourgogne | Nouvelle methode pour detecter la presence de bacteries productrices de beta-lactamases. |
| GB201521899D0 (en) * | 2015-12-11 | 2016-01-27 | Mast Group Ltd | Extraction discs |
| US11286512B2 (en) * | 2016-06-27 | 2022-03-29 | Becton, Dickinson And Company | Compositions, methods, systems and/or kits for detecting antimicrobial resistance in bacteria |
| US20200131558A1 (en) * | 2017-04-21 | 2020-04-30 | Colorado State University Research Foundation | Paper-based assay for antimicrobial resistance |
| GB201712671D0 (en) * | 2017-08-07 | 2017-09-20 | Mast Group Ltd | Chromogenic Carbapenemase detection method |
| US11492653B2 (en) | 2017-08-14 | 2022-11-08 | University Of Louisville Research Foundation, Inc. | Methods and kits for detecting antibiotic-inactivating factors |
| EP3737770A4 (de) * | 2018-01-10 | 2022-02-09 | Selux Diagnostics Inc. | Assays zur verbesserung der genauigkeit automatisierter antimikrobieller anfälligkeitstests |
| WO2020018462A1 (en) | 2018-07-16 | 2020-01-23 | Brown University | A chromogenic beta-lactamase substrate |
| US11291997B2 (en) | 2018-08-02 | 2022-04-05 | Colorado State University Research Foundation | Rotary manifold for paper-based immunoassays |
| US12195755B2 (en) | 2019-05-20 | 2025-01-14 | Brown University | Placental lipid bilayer for cell-free molecular interaction studies |
| EP3976093A4 (de) * | 2019-05-28 | 2023-07-05 | Aybar Ecotechnologies Corp. | Antibakterielle pharmazeutische zusammensetzungen mit breitem spektrum mit lysozym und verfahren zur verwendung davon |
| WO2021007492A1 (en) * | 2019-07-10 | 2021-01-14 | SeLux Diagnostics, Inc. | Assays for improving automated antimicrobial susceptibility testing accuracy |
| US12509559B2 (en) | 2019-10-28 | 2025-12-30 | Brown University | Bacterial beta-lactamase responsive hydrogels |
| CN111041067A (zh) * | 2019-12-20 | 2020-04-21 | 赛莱克斯(深圳)科技有限公司 | 一种检测β-内酰胺酶及其抑制复合剂耐药性的试剂与方法 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3019451A1 (de) | 1980-05-21 | 1981-11-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagens zur bestimmung von (beta) -lactamasen |
| GB2093994B (en) | 1981-03-03 | 1984-10-24 | Nat Res Dev | Idendification of beta-lactamase |
| WO1982003090A1 (en) | 1981-03-03 | 1982-09-16 | James Richard | Method and kit for identification of beta-lactamases |
| WO1987000196A1 (en) | 1985-07-09 | 1987-01-15 | Quadrant Bioresources Limited | Protection of proteins and the like |
| US4965193A (en) | 1984-08-06 | 1990-10-23 | Washington Research Foundation | Detection of microbial beta-lactamase |
| US4740459A (en) | 1984-08-06 | 1988-04-26 | Washington Research Foundation | Fluorescence assay for microbial beta-lactamase |
| US4712310A (en) | 1986-09-15 | 1987-12-15 | E. I. Du Pont De Nemours And Company | Co-spray technique |
| JPH0787800B2 (ja) | 1991-05-06 | 1995-09-27 | バクスター、ダイアグノスチックス、インコーポレイテッド | 迅速誘導可能β―ラクタマーゼスクリーン試験 |
| US5776563A (en) | 1991-08-19 | 1998-07-07 | Abaxis, Inc. | Dried chemical compositions |
| JP3082374B2 (ja) * | 1991-11-13 | 2000-08-28 | 富士レビオ株式会社 | １，２−ジオキセタン誘導体の安定化剤 |
| US5338843A (en) | 1992-01-30 | 1994-08-16 | Becton, Dickinson And Company | Fluorogenic and chromogenic β-lactamase substrates |
| DE69408541T2 (de) | 1993-11-23 | 1998-08-06 | Genentech, Inc., South San Francisco, Calif. | Kinaserezeptoraktivierungstest |
| US7427680B2 (en) | 2001-01-12 | 2008-09-23 | The Regents Of The University Of California | Fluorogenic substrates for BETA-lactamase gene expression |
| US5741657A (en) | 1995-03-20 | 1998-04-21 | The Regents Of The University Of California | Fluorogenic substrates for β-lactamase and methods of use |
| EP0838025B1 (de) | 1995-07-13 | 2007-04-25 | Applera Corporation | Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren |
| US5955604A (en) | 1996-10-15 | 1999-09-21 | The Regents Of The University Of California | Substrates for β-lactamase and uses thereof |
| US6096272A (en) | 1997-05-23 | 2000-08-01 | Becton Dickinson & Company | Automated microbiological testing apparatus and methods therefor |
| USD421498S (en) | 1997-05-23 | 2000-03-07 | Becton, Dickinson And Company | Microbiological test panel |
| US5922593A (en) | 1997-05-23 | 1999-07-13 | Becton, Dickinson And Company | Microbiological test panel and method therefor |
| JP2002504122A (ja) * | 1997-06-13 | 2002-02-05 | ノースウエスタン ユニバーシティー | ベータラクタマーゼ阻害剤及びその使用方法 |
| US5995604A (en) * | 1997-06-20 | 1999-11-30 | Nortel Networks Corporation | Method of preventing fraudulent toll calls by key system users |
| US6284461B1 (en) * | 1998-04-28 | 2001-09-04 | Aurora Biosciences Corporation | Use of inhibitors in reporter assays |
| JP4003993B2 (ja) * | 1998-07-17 | 2007-11-07 | 富士フイルム株式会社 | 乾式分析要素の製造方法及び乾式分析要素 |
| US6242223B1 (en) * | 1998-09-28 | 2001-06-05 | Creighton University | Primers for use in detecting beta-lactamases |
| US20020115642A1 (en) | 2000-05-02 | 2002-08-22 | Chan Ming Fai | Beta-lactam antibiotics |
| US6849422B1 (en) * | 2000-05-31 | 2005-02-01 | Becton, Dickinson And Company | System and method for analyzing antibiotic susceptibility of biological samples using redox and turbidity measurments to ascertain minimum inhibitory concentrations (MICs) |
| CA2423328C (en) | 2000-09-22 | 2010-01-12 | Zenyaku Kogyo Kabushiki Kaisha | Cephem compound and esbl-detecting reagent containing the same |
| ES2180416B1 (es) | 2001-03-12 | 2004-06-01 | BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. | Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen. |
| US7109294B2 (en) | 2001-09-18 | 2006-09-19 | Trustees Of Dartmouth College | Bacterial glycosyltransferase polypeptides involved in antibiotic resistance |
| KR100887429B1 (ko) | 2001-10-22 | 2009-03-09 | 돔페 파르마 에스.피.에이. | 초임계 유체 공정: 단백질 미세입자의 제조 및 그의 안정화 |
| JP2005519623A (ja) | 2002-03-13 | 2005-07-07 | クレイトン ユニヴァーシティー | 抗生物質不活性化酵素を検出するための装置及び方法 |
| US7291480B2 (en) | 2002-03-13 | 2007-11-06 | Black Jennifer A | Device and method for detecting antibiotic-inactivating enzymes |
| JP2004016694A (ja) * | 2002-06-20 | 2004-01-22 | Matsushita Electric Ind Co Ltd | 電動調理機 |
| AU2003252136A1 (en) | 2002-07-24 | 2004-02-09 | Ptc Therapeutics, Inc. | METHODS FOR IDENTIFYING SMALL MOLEDULES THAT MODULATE PREMATURE TRANSLATION TERMINATION AND NONSENSE MEDIATED mRNA DECAY |
| CN1729299A (zh) * | 2002-10-29 | 2006-02-01 | 昭和药品化工株式会社 | β－内酰胺酶检测试剂组合物、检测试剂盒及检测方法 |
| JP2004166694A (ja) * | 2002-10-29 | 2004-06-17 | Showa Yakuhin Kako Kk | β−ラクタマーゼ検出試薬組成物、検出キット及び検出方法 |
| US20040241779A1 (en) | 2003-02-24 | 2004-12-02 | Piasio Roger N. | Dry chemistry, lateral flow-reconstituted chromatographic enzyme-driven assays |
| EP1606414B1 (de) | 2003-03-17 | 2009-12-23 | Charles River Laboratories, Inc. | Methoden und zusammensetzungen für den nachweis mikrobieller verunreinigungen |
| RU2240136C1 (ru) | 2003-04-10 | 2004-11-20 | Государственное учреждение "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н.Габричевского МЗ РФ" | Композиция, содержащая иммуноглобулины и целевые добавки |
| SE0302840D0 (sv) | 2003-10-29 | 2003-10-29 | Affibody Ab | Detection method |
| WO2005071096A2 (en) | 2004-01-21 | 2005-08-04 | Molecular Probes, Inc. | Derivatives of cephalosporin and clavulanic acid for detecting beta-lacamase in a sample |
| JPWO2006043558A1 (ja) * | 2004-10-19 | 2008-05-22 | 財団法人ヒューマンサイエンス振興財団 | 細菌が産生するβ−ラクタマーゼのクラスを識別する方法 |
| US20070259348A1 (en) | 2005-05-03 | 2007-11-08 | Handylab, Inc. | Lyophilized pellets |
| ES2820430T3 (es) | 2005-05-09 | 2021-04-21 | Labrador Diagnostics Llc | Sistemas de fluidos para centros de atención y usos de los mismos |
| JP4874008B2 (ja) | 2005-07-01 | 2012-02-08 | 水ｉｎｇ株式会社 | 細菌を検出する方法およびその装置 |
| US20100291543A1 (en) * | 2007-02-05 | 2010-11-18 | Rachel De Las Heras | Homogeneous in vitro fec assays and components |
| MX2009013059A (es) | 2007-06-15 | 2010-01-15 | Basf Se | Procedimientos para la preparacion de compuestos de pirazol sustituidos con difluorometilo. |
| US8097434B2 (en) | 2007-10-19 | 2012-01-17 | Becton, Dickinson And Company | Methods for the detection of beta-lactamases |
| US20100209927A1 (en) | 2007-11-06 | 2010-08-19 | Menon Vinod P | Processing device tablet |
| WO2009114921A1 (en) * | 2008-03-17 | 2009-09-24 | Dmitrienko Gary I | INHIBITORS OF CLASS B AND CLASS D β-LACTAMASES |
| WO2010004778A1 (ja) | 2008-07-08 | 2010-01-14 | コニカミノルタエムジー株式会社 | 平版印刷版材料用の現像液および平版印刷版材料 |
| WO2010047778A1 (en) | 2008-10-20 | 2010-04-29 | Becton Dickinson And Company | Compositions for the detection of intracellular bacterial targets and other intracellular microorganism targets |
| CN107881210A (zh) * | 2010-08-19 | 2018-04-06 | 伊拉斯谟大学鹿特丹医药中心 | 表征微生物中抗生素抗性的方法和设备 |
| FR3024465B1 (fr) * | 2014-07-30 | 2018-03-23 | Biomerieux | Caracterisation de micro-organismes par maldi-tof |
-
2008
- 2008-10-20 US US12/254,594 patent/US8097434B2/en active Active
- 2008-10-20 EP EP08840533A patent/EP2207893B1/de active Active
- 2008-10-20 WO PCT/US2008/011934 patent/WO2009051838A1/en not_active Ceased
- 2008-10-20 AT AT08840533T patent/ATE539165T1/de active
- 2008-10-20 JP JP2010529976A patent/JP5628677B2/ja active Active
-
2011
- 2011-11-30 US US13/307,426 patent/US8389234B2/en active Active
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2013
- 2013-02-27 US US13/778,767 patent/US9085794B2/en active Active
-
2014
- 2014-10-02 JP JP2014204231A patent/JP6220759B2/ja active Active
-
2015
- 2015-06-22 US US14/745,722 patent/US9902989B2/en active Active
-
2017
- 2017-10-02 JP JP2017192997A patent/JP6438099B2/ja active Active
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2018
- 2018-02-26 US US15/905,422 patent/US10704079B2/en active Active
- 2018-11-15 JP JP2018214704A patent/JP6863955B2/ja active Active
-
2020
- 2020-07-02 US US16/920,276 patent/US11572579B2/en active Active
-
2021
- 2021-04-01 JP JP2021063047A patent/JP7234280B2/ja active Active
-
2023
- 2023-02-06 US US18/165,051 patent/US20240018567A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20210155969A1 (en) | 2021-05-27 |
| EP2207893B1 (de) | 2011-12-28 |
| JP2019022528A (ja) | 2019-02-14 |
| JP2021104043A (ja) | 2021-07-26 |
| JP6438099B2 (ja) | 2018-12-12 |
| JP5628677B2 (ja) | 2014-11-19 |
| US9902989B2 (en) | 2018-02-27 |
| JP2011500057A (ja) | 2011-01-06 |
| US8097434B2 (en) | 2012-01-17 |
| JP6220759B2 (ja) | 2017-10-25 |
| US20120077215A1 (en) | 2012-03-29 |
| US20160138076A1 (en) | 2016-05-19 |
| US11572579B2 (en) | 2023-02-07 |
| US20090117601A1 (en) | 2009-05-07 |
| US8389234B2 (en) | 2013-03-05 |
| US9085794B2 (en) | 2015-07-21 |
| US20140080164A1 (en) | 2014-03-20 |
| US20240018567A1 (en) | 2024-01-18 |
| US10704079B2 (en) | 2020-07-07 |
| JP2015002749A (ja) | 2015-01-08 |
| WO2009051838A1 (en) | 2009-04-23 |
| JP2018029607A (ja) | 2018-03-01 |
| EP2207893A1 (de) | 2010-07-21 |
| JP7234280B2 (ja) | 2023-03-07 |
| JP6863955B2 (ja) | 2021-04-21 |
| US20180334701A1 (en) | 2018-11-22 |
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