ATE541938T1 - Expression viraler proteine in pflanzen - Google Patents

Expression viraler proteine in pflanzen

Info

Publication number
ATE541938T1
ATE541938T1 AT06740997T AT06740997T ATE541938T1 AT E541938 T1 ATE541938 T1 AT E541938T1 AT 06740997 T AT06740997 T AT 06740997T AT 06740997 T AT06740997 T AT 06740997T AT E541938 T1 ATE541938 T1 AT E541938T1
Authority
AT
Austria
Prior art keywords
plant
influenza virus
plants
vector
hpv
Prior art date
Application number
AT06740997T
Other languages
English (en)
Inventor
Anna-Lise Williamson
Edward Peter Rybicki
James Malcolm Maclean
Inga Isabel Becker-Hitzeroth
Original Assignee
Univ Cape Town
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cape Town filed Critical Univ Cape Town
Application granted granted Critical
Publication of ATE541938T1 publication Critical patent/ATE541938T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/11—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06740997T 2005-04-29 2006-05-02 Expression viraler proteine in pflanzen ATE541938T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA200503454 2005-04-29
PCT/ZA2006/000063 WO2006119516A2 (en) 2005-04-29 2006-05-02 Expression of viral proteins in plants

Publications (1)

Publication Number Publication Date
ATE541938T1 true ATE541938T1 (de) 2012-02-15

Family

ID=37308754

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06740997T ATE541938T1 (de) 2005-04-29 2006-05-02 Expression viraler proteine in pflanzen

Country Status (10)

Country Link
US (2) US8535930B2 (de)
EP (2) EP2374892B1 (de)
CN (2) CN101166827B (de)
AT (1) ATE541938T1 (de)
DK (1) DK2374892T3 (de)
ES (2) ES2662118T3 (de)
PL (2) PL2374892T3 (de)
PT (1) PT2374892T (de)
WO (1) WO2006119516A2 (de)
ZA (2) ZA200803486B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007040568A2 (en) * 2004-12-01 2007-04-12 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State Univeristy Production and use of human butyrylcholinesterase
CA3184778A1 (en) * 2006-07-28 2008-01-31 The Trustees Of The University Of Pennsylvania Hiv consensus envelope sequences and methods for using same
WO2008091657A1 (en) * 2007-01-23 2008-07-31 Academia Sinica Flu vaccines and methods of use thereof
CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
KR101255419B1 (ko) * 2007-11-12 2013-04-17 이노비오 파마수티컬즈, 인크. 인플루엔자 바이러스의 다중 아형에 대한 신규 백신
NZ587108A (en) 2007-11-27 2013-04-26 Medicago Inc Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin
US7981428B2 (en) * 2008-01-23 2011-07-19 Academia Sinica Flu vaccines and methods of use thereof
US10689633B2 (en) 2008-02-29 2020-06-23 The Trustees Of The University Of Pennsylvania Expression of β-mannanase in chloroplasts and its utilization in lignocellulosic woody biomass hydrolysis
DK2294202T3 (en) 2008-07-08 2015-08-31 Medicago Inc SOLUBLE RECOMBINANT INFLUENZA ANTIGENES
KR101745925B1 (ko) 2008-07-18 2017-06-12 메디카고 인코포레이티드 신규 인플루엔자 바이러스 면역화 에피토프
SI2445928T1 (en) 2009-06-24 2018-05-31 Medicago Inc. HYPER PARTICULARS, SIMILAR VIRUSES OF GRIPE, WHICH HAVE EXPOSED HEMAGLUTININE
SG178918A1 (en) 2009-09-22 2012-04-27 Medicago Inc Method of preparing plant-derived vlps
WO2011077371A1 (en) * 2009-12-22 2011-06-30 University Of Cape Town Method for enhancing the expression of hpv l1
CN101892248B (zh) * 2010-04-29 2012-04-18 王世霞 禽流感h5 ha抗原的单克隆抗体
CN102533722B (zh) * 2010-12-24 2014-03-12 北京义翘神州生物技术有限公司 一种通过温度突变提高哺乳动物细胞重组蛋白瞬时表达的方法
EP2665817A1 (de) * 2011-01-17 2013-11-27 Philip Morris Products S.a.s. Vektoren für nukleinsäureexpression in pflanzen
WO2012098119A2 (en) * 2011-01-17 2012-07-26 Philip Morris Products S.A. Protein expression in plants
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
TWI700368B (zh) * 2011-09-30 2020-08-01 苜蓿股份有限公司 增加植物類病毒顆粒產率
MY184076A (en) 2011-12-01 2021-03-17 Univ Cape Town Hpv chimaeric particle
US10159884B2 (en) 2012-11-09 2018-12-25 Wilson Sporting Goods Co. Basketball make-miss shot sensing
US9901801B2 (en) 2012-11-09 2018-02-27 Wilson Sporting Goods Co. Basketball sensing apparatus
JP2016516415A (ja) 2013-03-28 2016-06-09 メディカゴ インコーポレイテッド 植物におけるインフルエンザウイルス様粒子の生成
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
BR112016015875A2 (pt) 2014-01-10 2017-09-19 Medicago Inc Elementos intensificadores de cpmv
CA2944422A1 (en) * 2014-04-10 2015-10-15 Mitsubishi Chemical Corporation Method for producing a useful protein using a plant
US9916001B2 (en) 2014-07-08 2018-03-13 Wilson Sporting Goods Co. Sport equipment input mode control
WO2016004536A1 (en) * 2014-07-11 2016-01-14 Medicago Inc. Modifying protein production in plants
CN109385445A (zh) * 2017-08-09 2019-02-26 北京睿诚海汇健康科技有限公司 植物作为宿主在表达贝伐抗体中的应用
CN114106206B (zh) * 2021-12-02 2023-02-28 猎境(嘉兴)生物科技有限公司 一种利用植物膜系统生产重组疫苗的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7129391B1 (en) * 1988-09-26 2006-10-31 Auburn University Universal chloroplast integration and expression vectors, transformed plants and products thereof
US20010053367A1 (en) * 1991-08-26 2001-12-20 Prodigene, Inc. Vaccines expressed in plants
AU733792B2 (en) * 1997-01-17 2001-05-24 Scripps Research Institute, The RNA binding protein and binding site useful for expression of recombinant molecules
WO2003018624A1 (en) * 2001-08-31 2003-03-06 University Of Cape Town Vectors, constructs, and transgenic plants for hpv-11 and hpv-16 l1 capsid protein
DK1506222T3 (da) 2002-05-17 2009-07-06 Univ Cape Town Kimæriske, humane papillomavirus16 L1-proteiner omfattende et L2-peptid, viruslignende partikler fremstillet deraf samt en fremgangsmåde til at fremstille partiklerne
AU2003253781A1 (en) 2002-07-03 2004-01-23 University Of Central Florida Expression of human interferon in transgenic chloroplasts
WO2005011367A1 (en) 2003-07-03 2005-02-10 University Of Central Florida A chloroplast transgenic approach to express and purify human serum albumin, a protein highly susceptible to proteolytic degradation

Also Published As

Publication number Publication date
EP2374892B1 (de) 2018-02-14
EP2374892A3 (de) 2011-12-28
US8535930B2 (en) 2013-09-17
ES2381200T3 (es) 2012-05-24
US9017987B2 (en) 2015-04-28
CN101166827A (zh) 2008-04-23
US20130130314A1 (en) 2013-05-23
PL2374892T3 (pl) 2018-06-29
PT2374892T (pt) 2018-03-29
ZA201204565B (en) 2014-03-26
ES2662118T3 (es) 2018-04-05
EP1883701B1 (de) 2012-01-18
CN103031310B (zh) 2018-09-14
WO2006119516A2 (en) 2006-11-09
CN103031310A (zh) 2013-04-10
DK2374892T3 (en) 2018-03-12
ZA200803486B (en) 2012-09-26
WO2006119516A3 (en) 2007-06-28
EP1883701A2 (de) 2008-02-06
US20090220543A1 (en) 2009-09-03
CN101166827B (zh) 2013-09-04
PL1883701T3 (pl) 2012-06-29
EP2374892A2 (de) 2011-10-12

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