ATE541944T1 - Polynukleotidprimer - Google Patents

Polynukleotidprimer

Info

Publication number
ATE541944T1
ATE541944T1 AT06726631T AT06726631T ATE541944T1 AT E541944 T1 ATE541944 T1 AT E541944T1 AT 06726631 T AT06726631 T AT 06726631T AT 06726631 T AT06726631 T AT 06726631T AT E541944 T1 ATE541944 T1 AT E541944T1
Authority
AT
Austria
Prior art keywords
polynucleotide primer
primer
polynucleotide
sequence
nucleotides
Prior art date
Application number
AT06726631T
Other languages
English (en)
Inventor
Nicola Jo Thelwell
Paul Francis Ravetto
David Mark Whitcombe
Original Assignee
Qiagen Manchester Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34586669&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE541944(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Qiagen Manchester Ltd filed Critical Qiagen Manchester Ltd
Application granted granted Critical
Publication of ATE541944T1 publication Critical patent/ATE541944T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT06726631T 2005-04-04 2006-04-04 Polynukleotidprimer ATE541944T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0506807A GB2424886A (en) 2005-04-04 2005-04-04 Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations
PCT/GB2006/001227 WO2006106316A2 (en) 2005-04-04 2006-04-04 Polynucleotide primers

Publications (1)

Publication Number Publication Date
ATE541944T1 true ATE541944T1 (de) 2012-02-15

Family

ID=34586669

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06726631T ATE541944T1 (de) 2005-04-04 2006-04-04 Polynukleotidprimer

Country Status (6)

Country Link
US (3) US9029084B2 (de)
EP (2) EP1866438B2 (de)
JP (1) JP5761891B2 (de)
AT (1) ATE541944T1 (de)
GB (1) GB2424886A (de)
WO (1) WO2006106316A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0520530A2 (pt) * 2005-10-05 2009-09-29 Astrazeneca Uk Ltd método para predizer ou monitorar a resposta de um paciente a uma droga receptora do erbb
US8999634B2 (en) 2007-04-27 2015-04-07 Quest Diagnostics Investments Incorporated Nucleic acid detection combining amplification with fragmentation
GB2453173A (en) * 2007-09-28 2009-04-01 Dxs Ltd Polynucleotide primers
JP2010279264A (ja) * 2009-06-03 2010-12-16 Tottori Univ Ｅｇｆｒ遺伝子変異検出プライマーセット、それを含むｅｇｆｒ遺伝子変異検出キット、およびそれを用いてｅｇｆｒ遺伝子変異検出を行うための核酸増幅装置
CN102234683B (zh) * 2010-04-23 2013-07-17 广州益善生物技术有限公司 一种egfr基因突变检测液相芯片
KR101536318B1 (ko) 2010-10-29 2015-07-13 아크레이 가부시키가이샤 Ｅｇｆｒ 유전자의 다형(多型) 검출용 프로브, 증폭용 프라이머 및 그 용도
JP5860667B2 (ja) 2010-10-29 2016-02-16 アークレイ株式会社 Ｅｇｆｒエクソン２１ｌ８５８ｒ遺伝子多型検出用プライマーセット及びその用途
US20120164641A1 (en) * 2010-12-22 2012-06-28 Roche Molecular Systems, Inc. Methods and Compositions for Detecting Mutation in the Human Epidermal Growth Factor Receptor Gene
WO2012157684A1 (ja) * 2011-05-16 2012-11-22 地方独立行政法人 大阪府立病院機構 血中ｄｎａの定量的検出による悪性新生物の病勢の進行を評価する方法
CN103184274A (zh) * 2011-12-27 2013-07-03 上海复星医学科技发展有限公司 一种ldr技术的egfr突变检测试剂盒
CN102747157B (zh) * 2012-07-16 2014-01-22 武汉海吉力生物科技有限公司 用于检测人类egfr基因突变的引物、探针、试剂盒及检测方法
US20140341884A1 (en) * 2012-12-04 2014-11-20 Roche Molecular Systems, Inc. Novel Complex Mutations in the Epidermal Growth Factor Receptor Kinase Domain
US9994914B2 (en) 2014-10-09 2018-06-12 Roche Molecular Systems, Inc. Mutation in the epidermal growth factor receptor kinase domain

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830713A (en) * 1986-11-04 1998-11-03 Protein Polymer Technologies, Inc. Methods for preparing synthetic repetitive DNA
FR2628027B1 (fr) 1988-03-03 1990-07-20 Hutchinson Procede de fabrication de pieces de carrosserie d'automobile, notamment d'aileron ou becquet arriere, et pieces obtenues par mise en oeuvre de ce procede
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
US5993813A (en) * 1988-10-19 1999-11-30 The Dow Chemical Company Family of high affinity, modified antibodies for cancer treatment
CA2066428C (en) * 1989-09-08 2000-11-28 Bert Vogelstein Structural alterations of the egf receptor gene in human gliomas
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
WO1994004689A1 (en) * 1992-08-14 1994-03-03 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Recombinant toxin with increased half-life
ES2167391T3 (es) * 1994-09-16 2002-05-16 Merck Patent Gmbh Inmunoconjugados ii.
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US6057156A (en) * 1997-01-31 2000-05-02 Robozyme Pharmaceuticals, Inc. Enzymatic nucleic acid treatment of diseases or conditions related to levels of epidermal growth factor receptors
US20030032090A1 (en) 1997-05-07 2003-02-13 Schering Corporation, A New Jersey Corporation Human receptor proteins; related reagents and methods
US6528640B1 (en) * 1997-11-05 2003-03-04 Ribozyme Pharmaceuticals, Incorporated Synthetic ribonucleic acids with RNAse activity
US6617438B1 (en) * 1997-11-05 2003-09-09 Sirna Therapeutics, Inc. Oligoribonucleotides with enzymatic activity
DE19813317A1 (de) * 1998-03-26 1999-09-30 Roche Diagnostics Gmbh Verbessertes Verfahren zur Primer Extension Präamplifikations-PCR
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
US7294482B2 (en) 1998-11-19 2007-11-13 Millennium Pharmaceuticals, Inc. EGF-like nucleic acids
JP2002541795A (ja) 1999-04-12 2002-12-10 リボザイム・ファーマシューティカルズ・インコーポレーテッド 核酸分子を用いるリプレッサー遺伝子の制御
AU2001245489A1 (en) * 2000-03-07 2001-09-17 Whitehead Institute For Biomedical Research Human single nucleotide polymorphisms
US6365355B1 (en) * 2000-03-28 2002-04-02 The Regents Of The University Of California Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches
WO2003057926A1 (en) 2002-01-08 2003-07-17 Chiron Corporation Gene products differentially expressed in cancerous breast cells and their methods of use
AUPQ909100A0 (en) 2000-07-28 2000-08-24 Ludwig Institute For Cancer Research A method for diagnosis and treatment
US6444465B1 (en) * 2000-09-29 2002-09-03 Isis Pharmaceuticals, Inc. Antinsense modulation of Her-1 expression
US7563946B2 (en) * 2000-11-13 2009-07-21 Cropdesign, N.V. Plant development regulating gene and its uses
WO2002042462A2 (en) * 2000-11-27 2002-05-30 Praecis Pharmaceuticals Inc. Therapeutic agents and methods of use thereof for treating an amyloidogenic disease
AU2002250293B2 (en) * 2001-03-09 2007-10-11 Arnason, Barry G. Mr Polymeric immunoglobulin fusion proteins that target low-affinity FCGammaReceptors
WO2003070912A2 (en) * 2001-06-06 2003-08-28 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
CA2400601A1 (en) * 2001-08-31 2003-02-28 University Of Utah Research Foundation Real-time gene quantification with internal standards
EP2385137A1 (de) 2002-07-31 2011-11-09 University of Southern California Polymorphismen zur Vorhersage des Krankheits- und Behandlungsausgangs
EP1403379A1 (de) 2002-09-24 2004-03-31 QIAGEN GmbH Verbesserte Koamplifikation von Nukleinsäuren
US20060211640A1 (en) 2002-09-25 2006-09-21 Kane Christopher D Antisense modulation of farnesoid X receptor expression
WO2004042054A1 (ja) * 2002-10-23 2004-05-21 Hubit Genomix, Inc. 歯周疾患に関連する遺伝的多型
US7910295B2 (en) * 2002-11-14 2011-03-22 John Wayne Cancer Institute Detection of micro metastasis of melanoma and breast cancer in paraffin-embedded tumor draining lymph nodes by multimarker quantitative RT-PCR
EP3611273A1 (de) * 2004-03-31 2020-02-19 The General Hospital Corporation Verfahren zur bestimmung des ansprechens von krebs auf den epidermalen wachstumsfaktorrezeptor gerichtete behandlungen
EP2527460B1 (de) * 2004-05-27 2014-12-24 The Regents of The University of Colorado Verfahren zur Vorhersage der klinischen Resultate in Bezug auf epidermale Wachstumsfaktor-Rezeptorhemmer von Krebspatienten
EP3042964A1 (de) 2004-06-04 2016-07-13 Genentech, Inc. Egfr-mutationen

Also Published As

Publication number Publication date
WO2006106316A3 (en) 2007-02-15
JP2008534025A (ja) 2008-08-28
EP1866438A2 (de) 2007-12-19
US9029084B2 (en) 2015-05-12
US20130323736A1 (en) 2013-12-05
EP1866438B2 (de) 2015-12-23
EP2314717B1 (de) 2016-08-31
GB2424886A (en) 2006-10-11
US20150211076A1 (en) 2015-07-30
WO2006106316A2 (en) 2006-10-12
EP1866438B1 (de) 2012-01-18
US20080261219A1 (en) 2008-10-23
GB0506807D0 (en) 2005-05-11
EP2314717A1 (de) 2011-04-27
JP5761891B2 (ja) 2015-08-12

Similar Documents

Publication Publication Date Title
EG25300A (en) Process for the manufacture of 1,2-dichloroethane.
EG25281A (en) Process for the manufacture of 1,2-dichloroethane.
EG25147A (en) Process for the manufacture of 1,2-dichloroethane.
BRPI0411897A (pt) pirroldihidroisoquinolinas como inibidores de pde10
AP2005003365A0 (en) Hiv inhibiting 1, 2, 4-triazines.
DE602005010109D1 (de) 1,1a,5,5a-tetrahydro-3-thia-cyclopropaäaüpentaleneptor-agonisten
WO2008146745A1 (ja) 新規なリゾホスファチジン酸アシル基転移酵素遺伝子
NO20053246D0 (no) Kondensert 1,3-dihydroimidazol-ringforbindelse.
WO2005047545A3 (en) Microarray controls
DK2135949T3 (da) MCP-1-bindende nukleinsyrer
WO2008143668A3 (en) Indoleamine-2, 3-dioxygenase-2
GB0506807D0 (en) Polynucleotide primers
DK1645626T3 (da) Cellelinie
CY1116649T1 (el) Τεχνητη dna αλληλουχια με βελτιστοποιημενη λειτουργια οδηγου σε 5' (5-utr) για βελτιωμενη εκφραση ετερολογων πρωτεϊνων σε φυτα
NO20052754D0 (no) Kaminovn, samt anvendelse av denne.
WO2008107771A3 (en) 2',3'-di-o-acyl-5-fluoronucleosides
DK1664102T3 (da) Isoleret photoprotein mtclytin, samt dets anvendelse
NL1030010A1 (nl) 4-Amino-gesubstitueerde-2-gesubstitueerde-1,2,3,4- tetrahydrochinolineverbindingen.
WO2007144492A3 (fr) Peptides a activite anti-proliferative
ES1052327Y (es) Gasometro de membrana mejorado.
GB0625182D0 (en) Supplementary patent to 0624018.8 Claims 1a,2,3,4 & 5
WO2006035273A3 (en) Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis
TW200617021A (en) Isolated photoprotein aequorin y89f, and its use
FR2864104B1 (fr) Sequences nucleotidiques promotrices inductibles par infection par les pathogenes.
DE202005000302U1 (de) Jacke mit integrierter Schwimmweste