ATE542893T1 - Verfahren zur herstellung von l-lysin - Google Patents
Verfahren zur herstellung von l-lysinInfo
- Publication number
- ATE542893T1 ATE542893T1 AT09180108T AT09180108T ATE542893T1 AT E542893 T1 ATE542893 T1 AT E542893T1 AT 09180108 T AT09180108 T AT 09180108T AT 09180108 T AT09180108 T AT 09180108T AT E542893 T1 ATE542893 T1 AT E542893T1
- Authority
- AT
- Austria
- Prior art keywords
- lysine
- culture
- producing
- medium
- glyceraldehyde
- Prior art date
Links
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title abstract 9
- 238000004519 manufacturing process Methods 0.000 title 1
- 235000019766 L-Lysine Nutrition 0.000 abstract 4
- 239000004472 Lysine Substances 0.000 abstract 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 abstract 1
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008325952A JP2010142200A (ja) | 2008-12-22 | 2008-12-22 | L−リジンの製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE542893T1 true ATE542893T1 (de) | 2012-02-15 |
Family
ID=42101349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09180108T ATE542893T1 (de) | 2008-12-22 | 2009-12-21 | Verfahren zur herstellung von l-lysin |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2202299B1 (de) |
| JP (1) | JP2010142200A (de) |
| AT (1) | ATE542893T1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013074795A (ja) | 2010-02-08 | 2013-04-25 | Ajinomoto Co Inc | 変異型rpsA遺伝子及びL−アミノ酸の製造法 |
| CN108728249A (zh) * | 2018-06-15 | 2018-11-02 | 成都恒润高新科技股份有限公司 | 一种利用潲水制备生物柴油的方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5618596A (en) | 1979-07-23 | 1981-02-21 | Ajinomoto Co Inc | Production of l-lysine through fermentation process |
| JPH0783714B2 (ja) | 1983-08-29 | 1995-09-13 | 味の素株式会社 | 発酵法によるl―アミノ酸の製造法 |
| JPH06102028B2 (ja) | 1985-10-04 | 1994-12-14 | 協和醗酵工業株式会社 | アミノ酸の製造法 |
| FR2627508B1 (fr) | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
| DE3891417C5 (de) | 1988-10-25 | 2006-01-05 | Ajinomoto Co., Inc. | Verfahren zur Veränderung eines L-Threonin produzierenden Mikroorganismus und Verwendung eines so erhaltenen Mikroorganismus zur Herstellung von L-Threonin |
| JPH07108228B2 (ja) | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
| ATE203769T1 (de) | 1992-11-10 | 2001-08-15 | Ajinomoto Kk | Dna, die aspartokinase iii-mutanten kodiert und ihre verwendung zur herstellung von l-threonin durch fermentation |
| PL185681B1 (pl) | 1993-10-28 | 2003-07-31 | Ajinomoto Kk | Sposób wytwarzania L-aminokwasu przy użyciu mikroorganizmu |
| JPH07155184A (ja) | 1993-12-08 | 1995-06-20 | Ajinomoto Co Inc | 発酵法によるl−リジンの製造法 |
| JP3783065B2 (ja) | 1994-03-04 | 2006-06-07 | 味の素株式会社 | L−リジンの製造法 |
| KR100420743B1 (ko) | 1994-12-09 | 2004-05-24 | 아지노모토 가부시키가이샤 | 신규한리신데카복실라제유전자및l-리신의제조방법 |
| HU222503B1 (hu) | 1995-06-07 | 2003-07-28 | Ajinomoto Co., Inc. | Eljárás L-lizin termelésére |
| JP4032441B2 (ja) | 1995-08-30 | 2008-01-16 | 味の素株式会社 | L−アミノ酸の製造方法 |
| JP4075087B2 (ja) | 1996-12-05 | 2008-04-16 | 味の素株式会社 | L−リジンの製造法 |
| AU756507B2 (en) | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| JP2000157276A (ja) | 1998-11-24 | 2000-06-13 | Ajinomoto Co Inc | サーマス属細菌のl−リジン生合成系遺伝子 |
| RU2175351C2 (ru) | 1998-12-30 | 2001-10-27 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") | Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот |
| JP3965821B2 (ja) | 1999-03-09 | 2007-08-29 | 味の素株式会社 | L−リジンの製造法 |
| JP2000262288A (ja) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | コリネ型細菌の温度感受性プラスミド |
| JP2003135066A (ja) | 1999-03-19 | 2003-05-13 | Ajinomoto Co Inc | L−リジンの製造法 |
| EP1063288A3 (de) | 1999-06-15 | 2001-01-17 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von L-Lysin |
| JP2003144160A (ja) | 1999-07-02 | 2003-05-20 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| US6713289B2 (en) * | 1999-10-05 | 2004-03-30 | Degussa Ag | Nucleotide sequences which code for the eno gene |
| JP4380029B2 (ja) | 2000-07-05 | 2009-12-09 | 味の素株式会社 | 微生物を利用した物質の製造法 |
| JP4362959B2 (ja) | 2000-08-24 | 2009-11-11 | 味の素株式会社 | 塩基性アミノ酸の製造方法 |
| AU2001291796A1 (en) * | 2000-09-09 | 2002-03-22 | Degussa A.G. | Nucleotide sequences which code for the gap2 gene |
| DE10112992A1 (de) * | 2001-03-17 | 2002-09-26 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| WO2003008614A2 (en) | 2001-07-18 | 2003-01-30 | Degussa Ag | Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced suca or sucb gene |
| PL1651758T3 (pl) | 2003-07-29 | 2009-04-30 | Ajinomoto Kk | Sposób wytwarzania L-lizyny lub L-treoniny przy użyciu bakterii Escherichia o atenuowanej aktywności enzymu jabłczanowego |
| MXPA06003775A (es) | 2004-01-30 | 2006-06-14 | Ajinomoto Kk | Microorganismo productor de l-aminoacido y metodo para la produccion de l-aminoacido. |
| US20050181488A1 (en) | 2004-02-12 | 2005-08-18 | Akhverdian Valery Z. | Method for producing L-threonine using bacteria belonging to the genus Escherichia |
| CN103088080B (zh) | 2004-10-07 | 2016-02-17 | 味之素株式会社 | 生产碱性物质的方法 |
| KR100768748B1 (ko) * | 2004-12-30 | 2007-10-19 | 씨제이 주식회사 | 외래의 nadp 의존적 글리세르알데히드-3-포스페이트디히드로게나제 유전자를 포함하는 에세리키아 종 또는코리네박리움 종 미생물 및 그를 이용하여 l-라이신을생산하는 방법 |
| EP1838726A1 (de) | 2005-01-18 | 2007-10-03 | Ajinomoto Co., Inc. | L-aminosäure-produzierender mikroorganismus und verfahren zur herstellung von l-aminosäure |
| DE102005018835A1 (de) | 2005-04-22 | 2006-11-02 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| DE102005019040A1 (de) | 2005-04-23 | 2006-10-26 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| JP2009118740A (ja) | 2006-03-03 | 2009-06-04 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010110217A (ja) | 2007-02-22 | 2010-05-20 | Ajinomoto Co Inc | L−アミノ酸生産菌及びl−アミノ酸の製造法 |
| DE102007051024A1 (de) | 2007-03-05 | 2008-09-11 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
-
2008
- 2008-12-22 JP JP2008325952A patent/JP2010142200A/ja active Pending
-
2009
- 2009-12-21 EP EP09180108A patent/EP2202299B1/de not_active Not-in-force
- 2009-12-21 AT AT09180108T patent/ATE542893T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2202299A1 (de) | 2010-06-30 |
| EP2202299B1 (de) | 2012-01-25 |
| JP2010142200A (ja) | 2010-07-01 |
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