ATE544446T1 - Stabilisierte feste wirkstoffdispersionen in einem organischen träger und verfahren zur deren herstellung - Google Patents
Stabilisierte feste wirkstoffdispersionen in einem organischen träger und verfahren zur deren herstellungInfo
- Publication number
- ATE544446T1 ATE544446T1 AT03813592T AT03813592T ATE544446T1 AT E544446 T1 ATE544446 T1 AT E544446T1 AT 03813592 T AT03813592 T AT 03813592T AT 03813592 T AT03813592 T AT 03813592T AT E544446 T1 ATE544446 T1 AT E544446T1
- Authority
- AT
- Austria
- Prior art keywords
- drug
- dispersions
- organic carrier
- production
- solid active
- Prior art date
Links
- 239000006185 dispersion Substances 0.000 title abstract 3
- 239000007787 solid Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 239000008139 complexing agent Substances 0.000 abstract 1
- 229920006037 cross link polymer Polymers 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000005672 electromagnetic field Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002748A ITMI20022748A1 (it) | 2002-12-23 | 2002-12-23 | Dispersioni solide stabilizzate di farmaco in un carrier organico e procedimento per la loro preparazione. |
| PCT/EP2003/014740 WO2004056340A2 (en) | 2002-12-23 | 2003-12-22 | Stabilised solid drug dispersions in an organic carrier and a process for preparing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE544446T1 true ATE544446T1 (de) | 2012-02-15 |
Family
ID=32676862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03813592T ATE544446T1 (de) | 2002-12-23 | 2003-12-22 | Stabilisierte feste wirkstoffdispersionen in einem organischen träger und verfahren zur deren herstellung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7951401B2 (de) |
| EP (1) | EP1581189B1 (de) |
| JP (1) | JP2006512344A (de) |
| AT (1) | ATE544446T1 (de) |
| AU (1) | AU2003303183B2 (de) |
| CA (1) | CA2529818C (de) |
| DK (1) | DK1581189T3 (de) |
| ES (1) | ES2382076T3 (de) |
| IT (1) | ITMI20022748A1 (de) |
| PT (1) | PT1581189E (de) |
| WO (1) | WO2004056340A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| CN102321234A (zh) * | 2005-05-24 | 2012-01-18 | 日立化成工业株式会社 | 共轭聚合物的制造方法 |
| US8642080B2 (en) | 2009-06-29 | 2014-02-04 | Bender Analytical Holdong B.V. | Drug delivery system comprising polyoxazoline and a bioactive agent |
| CN102293734A (zh) * | 2010-06-25 | 2011-12-28 | 江苏恒瑞医药股份有限公司 | 托伐普坦固体分散体及其制备方法 |
| US9327264B2 (en) * | 2011-01-31 | 2016-05-03 | Uchicago Argonne, Llc | Containerless synthesis of amorphous and nanophase organic materials |
| MX388963B (es) * | 2011-03-04 | 2025-03-20 | Gruenenthal Gmbh | Formulacion farmaceutica acuosa de tapentadol para administracion oral |
| PE20171651A1 (es) | 2015-03-27 | 2017-11-13 | Gruenenthal Chemie | Formulacion estable para administracion parenteral de tapentadol |
| EP3515412B1 (de) | 2016-09-23 | 2025-04-23 | Grünenthal GmbH | Stabile formulierungen zur parenteralen verabreichung von tapentadol |
| CA3172889C (en) | 2020-04-20 | 2024-05-28 | John Docherty | Compositions and methods for enhanced delivery of antiviral agents |
| WO2024227190A1 (en) * | 2023-04-28 | 2024-10-31 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Druggable formulation for mu/delta opioid antagonist for enhancing pain therapy and treatment of opioid withdrawal |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0677510B2 (ja) * | 1986-07-11 | 1994-10-05 | 雪印乳業株式会社 | マイクロ波による加熱調理方法とその加熱調理用容器 |
| US4999205A (en) * | 1989-08-17 | 1991-03-12 | Kalamazoo Holdings, Inc. | Curcumin complexed on water-dispersible substrates |
| JPH03215226A (ja) * | 1990-01-19 | 1991-09-20 | Matsushita Electric Ind Co Ltd | 電子レンジ用圧力調理容器 |
| JP2516524B2 (ja) | 1992-04-27 | 1996-07-24 | 大洋薬品工業株式会社 | 持続性製剤 |
| DE4223116A1 (de) * | 1992-04-30 | 1993-11-04 | Mikrowellen Labor Systeme | Vorrichtung zur verdampfungsbehandlung von vorzugsweise fluessigen stoffen, insbesondere reagenzstoffen, oder zum aufbereiten oder analysieren von probenmaterial |
| IT1264960B1 (it) * | 1993-11-11 | 1996-10-17 | Eniricerche Spa | Composizioni isocianato/epossido polimerizzabili mediante microonde per applicazioni tecnicamente impegnative |
| MX9605717A (es) * | 1994-05-18 | 1998-05-31 | Inhale Therapeutic Syst | Metodos y composiciones para la formulacion de polvo seco de interferones. |
| JPH08231165A (ja) * | 1994-12-28 | 1996-09-10 | Ntn Corp | ガイドシュー |
| TW487582B (en) * | 1995-08-11 | 2002-05-21 | Nissan Chemical Ind Ltd | Method for converting sparingly water-soluble medical substance to amorphous state |
| ATE273002T1 (de) * | 1996-06-28 | 2004-08-15 | Schering Corp | Feste lösung eines fungizids mit erhöhter bioverfügbarkeit |
| US5972381A (en) * | 1996-06-28 | 1999-10-26 | Schering Corporation | Solid solution of an antifungal agent with enhanced bioavailability |
| US6174873B1 (en) * | 1998-11-04 | 2001-01-16 | Supergen, Inc. | Oral administration of adenosine analogs |
| CA2389078A1 (en) * | 1999-10-29 | 2001-05-17 | Matthew J. Kampling | Polymer compositions suitable for microwave cooking applications |
| AU4684701A (en) * | 2000-04-19 | 2001-10-30 | Fujisawa Pharmaceutical Co., Ltd. | Solid dispersion with improved absorbability |
| CA2418490A1 (en) | 2000-08-11 | 2002-02-21 | Eisai Co., Ltd. | Drug-containing solid dispersion having improved solubility |
| FR2823209B1 (fr) * | 2001-04-04 | 2003-12-12 | Fournier Lab Sa | Nouvelles thiohydantoines et leur utilisation en therapeutique |
-
2002
- 2002-12-23 IT IT002748A patent/ITMI20022748A1/it unknown
-
2003
- 2003-12-22 JP JP2004561412A patent/JP2006512344A/ja active Pending
- 2003-12-22 AT AT03813592T patent/ATE544446T1/de active
- 2003-12-22 CA CA2529818A patent/CA2529818C/en not_active Expired - Fee Related
- 2003-12-22 DK DK03813592.7T patent/DK1581189T3/da active
- 2003-12-22 EP EP03813592A patent/EP1581189B1/de not_active Expired - Lifetime
- 2003-12-22 US US10/540,139 patent/US7951401B2/en not_active Expired - Fee Related
- 2003-12-22 PT PT03813592T patent/PT1581189E/pt unknown
- 2003-12-22 WO PCT/EP2003/014740 patent/WO2004056340A2/en not_active Ceased
- 2003-12-22 AU AU2003303183A patent/AU2003303183B2/en not_active Ceased
- 2003-12-22 ES ES03813592T patent/ES2382076T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20060051422A1 (en) | 2006-03-09 |
| JP2006512344A (ja) | 2006-04-13 |
| WO2004056340A3 (en) | 2004-11-11 |
| PT1581189E (pt) | 2012-05-25 |
| ES2382076T3 (es) | 2012-06-05 |
| AU2003303183B2 (en) | 2010-02-25 |
| CA2529818C (en) | 2012-10-30 |
| EP1581189A2 (de) | 2005-10-05 |
| EP1581189B1 (de) | 2012-02-08 |
| US7951401B2 (en) | 2011-05-31 |
| WO2004056340A2 (en) | 2004-07-08 |
| DK1581189T3 (da) | 2012-05-07 |
| CA2529818A1 (en) | 2004-07-08 |
| ITMI20022748A1 (it) | 2004-06-24 |
| AU2003303183A1 (en) | 2004-07-14 |
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