ATE544870T1 - Profilierung einer rezeptorfamilie - Google Patents

Profilierung einer rezeptorfamilie

Info

Publication number
ATE544870T1
ATE544870T1 AT07838435T AT07838435T ATE544870T1 AT E544870 T1 ATE544870 T1 AT E544870T1 AT 07838435 T AT07838435 T AT 07838435T AT 07838435 T AT07838435 T AT 07838435T AT E544870 T1 ATE544870 T1 AT E544870T1
Authority
AT
Austria
Prior art keywords
profiling
receptor family
biodetection
diagnostics
families
Prior art date
Application number
AT07838435T
Other languages
English (en)
Inventor
Tanya Landsman
David Livingston
Richard Martinelli
Yumei Huang
Benjamin Seigal
Dingxue Yan
James Coull
Andrew Stern
Original Assignee
Ensemble Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ensemble Therapeutics Corp filed Critical Ensemble Therapeutics Corp
Application granted granted Critical
Publication of ATE544870T1 publication Critical patent/ATE544870T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT07838435T 2006-09-18 2007-09-18 Profilierung einer rezeptorfamilie ATE544870T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US84533006P 2006-09-18 2006-09-18
US84785906P 2006-09-28 2006-09-28
US90536407P 2007-03-07 2007-03-07
US91802307P 2007-03-14 2007-03-14
PCT/US2007/020223 WO2008036273A2 (en) 2006-09-18 2007-09-18 Receptor family profiling

Publications (1)

Publication Number Publication Date
ATE544870T1 true ATE544870T1 (de) 2012-02-15

Family

ID=39201060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07838435T ATE544870T1 (de) 2006-09-18 2007-09-18 Profilierung einer rezeptorfamilie

Country Status (8)

Country Link
US (1) US20100159455A1 (de)
EP (1) EP2064348B1 (de)
JP (1) JP2010503860A (de)
AT (1) ATE544870T1 (de)
AU (1) AU2007297671A1 (de)
CA (1) CA2664014A1 (de)
DK (1) DK2064348T3 (de)
WO (1) WO2008036273A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401850A1 (de) 2001-06-20 2004-03-31 Nuevolution A/S Nukleosidderivate zur herstellung einer verbindungsbibliothek
US10731151B2 (en) 2002-03-15 2020-08-04 Nuevolution A/S Method for synthesising templated molecules
EP1539980B1 (de) 2002-08-01 2016-02-17 Nuevolution A/S MEHRSTUFENSYNTHESE VON MIT MATRIZEN ASSOZIIERTE MOLEKüLEN
EP2348124B1 (de) 2002-10-30 2013-12-11 Nuevolution A/S Synthese bifunktioneller Komplexe
WO2004056994A2 (en) 2002-12-19 2004-07-08 Nuevolution A/S Quasirandom structure and function guided synthesis methods
US20070026397A1 (en) 2003-02-21 2007-02-01 Nuevolution A/S Method for producing second-generation library
US11118215B2 (en) 2003-09-18 2021-09-14 Nuevolution A/S Method for obtaining structural information concerning an encoded molecule and method for selecting compounds
WO2007008276A2 (en) * 2005-05-03 2007-01-18 Ensemble Discovery Corporation Turnover probes and use thereof for nucleic acid detection
PT3305900T (pt) 2005-12-01 2021-10-27 Nuevolution As Métodos de codificação enzimática para síntese eficaz de bibliotecas grandes
WO2008054600A2 (en) * 2006-09-28 2008-05-08 Ensemble Discovery Corporation Compositions and methods for biodetection by nucleic acid-templated chemistry
US8426127B2 (en) * 2006-12-19 2013-04-23 Riken Fluorescence-producing molecule
CN101952719A (zh) * 2007-07-27 2011-01-19 通信改革公司 检测测定法及其用途
US20110059458A1 (en) * 2008-02-22 2011-03-10 Yumei Huang Compositions and methods for catalyzing dna-programmed chemistry
EP2189539B2 (de) * 2008-11-21 2018-06-13 Chimera Biotec GmbH Konjugatkomplexe zum Analytnachweis
WO2011005821A1 (en) 2009-07-09 2011-01-13 The Board Of Trustees Of The Leland Stanford Junior University Reductive release probes containing a chemoselectively cleavable alpha-azidoether linker and methods of use thereof
EP3540059A1 (de) 2010-04-16 2019-09-18 Nuevolution A/S Bifunktionelle komplexe und verfahren zur herstellung sowie verwendung derartiger komplexe
DE102014213783B3 (de) 2014-07-16 2015-06-18 Technische Universität Dresden Verfahren zur Identifizierung hochaffiner Komplexe aus zwei Liganden und einem Rezeptor, Vorrichtung zur Durchführung des Verfahrens und selbst-assemblierende chemische Bibliothek zur Verwendung in dem Verfahren
GB201518655D0 (en) * 2015-10-21 2015-12-02 Olink Ab Method for generating proximity probes
CN108866635B (zh) * 2017-05-09 2021-11-26 安升(上海)医药科技有限公司 多特异性蛋白药物及其文库、以及制备方法和应用
CN110885309B (zh) * 2019-11-19 2021-08-13 西北大学 一种pH敏感型探针分子及其应用
WO2025168224A1 (en) * 2024-02-08 2025-08-14 Leica Microsystems Cms Gmbh Marker and method for analysing a biological sample

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4008996B2 (ja) * 1997-12-24 2007-11-14 浜松ホトニクス株式会社 標的核酸検出プローブ
WO1999037806A2 (en) * 1998-01-27 1999-07-29 Cytocell Limited Modified nucleic acid probes and uses thereof
US6699710B1 (en) * 1998-02-25 2004-03-02 The United States Of America As Represented By The Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
EP1423400B2 (de) * 2001-03-19 2013-05-22 President and Fellows of Harvard College Entwicklung neuer molekularer funktionen
AU2002310846B2 (en) * 2002-03-08 2008-03-20 Eidgenossische Technische Hochschule Zurich Encoded self-assembling chemical libraries (ESACHEL)
JP2003294742A (ja) * 2002-03-29 2003-10-15 Inst Of Physical & Chemical Res ハイブリダイゼーション用基板及びその使用方法
US20040229294A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
WO2004016767A2 (en) * 2002-08-19 2004-02-26 The President And Fellows Of Harvard College Evolving new molecular function
CA2505515C (en) * 2002-11-07 2013-08-27 Erasmus Universiteit Rotterdam Fret probes and methods for detecting interacting molecules
US8017323B2 (en) * 2003-03-26 2011-09-13 President And Fellows Of Harvard College Free reactant use in nucleic acid-templated synthesis
WO2005074417A2 (en) * 2003-09-03 2005-08-18 Salk Institute For Biological Studies Multiple antigen detection assays and reagents
WO2006088860A2 (en) * 2005-02-14 2006-08-24 Beattie Kenneth L Universal fingerprinting chips and uses thereof
WO2007008276A2 (en) * 2005-05-03 2007-01-18 Ensemble Discovery Corporation Turnover probes and use thereof for nucleic acid detection
WO2006128138A2 (en) * 2005-05-26 2006-11-30 Ensemble Discovery Corportion Biodetection by nucleic acid-templated chemistry
WO2008054600A2 (en) * 2006-09-28 2008-05-08 Ensemble Discovery Corporation Compositions and methods for biodetection by nucleic acid-templated chemistry
CN101952719A (zh) * 2007-07-27 2011-01-19 通信改革公司 检测测定法及其用途

Also Published As

Publication number Publication date
WO2008036273A3 (en) 2008-06-19
DK2064348T3 (da) 2012-05-29
JP2010503860A (ja) 2010-02-04
EP2064348A2 (de) 2009-06-03
EP2064348B1 (de) 2012-02-08
AU2007297671A1 (en) 2008-03-27
CA2664014A1 (en) 2008-03-27
US20100159455A1 (en) 2010-06-24
WO2008036273A2 (en) 2008-03-27

Similar Documents

Publication Publication Date Title
ATE544870T1 (de) Profilierung einer rezeptorfamilie
NO20090047L (no) Anti-DLL4-antistoffer og fremgangsmater for anvendelse av disse
NO20083397L (no) Anti-EphB4-antistoffer og fremgangsmater for anvendelse av disse
NO20190202A1 (no) Anvendelse av anti-CGRP antagonist antistoff
ATE496051T1 (de) Pyrazolotetrahydropyridinderivate als orexinrezeptorantagonisten
UA95768C2 (ru) Антагонисты мускариновых рецепторов ацетилхолина
NO20083147L (no) Anti-OX40L-antistoffer og fremgangsmater for anvendelse av disse
CY2016005I1 (el) Αλκαλικη φωσφαταση στοχευμενη στα οστα, κιτ και μεθοδοι χρησης αυτων
CU24058B1 (es) Antagonistas de pcsk9
NL1032713A1 (nl) Histamine-3-receptorantagonisten.
NI200900081U (es) Anticuerpos agonistas de trkb y sus usos.
EA200702643A1 (ru) Антитела, связывающие tweak
EP1981902A4 (de) Nogo-rezeptorantagonisten
BRPI0922224A2 (pt) composições de inibidores de proteína tirosina quiinase receptora.
DE602007004999D1 (de) 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulen-derivate als orexinrezeptor-antagonisten
DK2094709T3 (da) Thiazol-pyrazolopyrimidiner som CRF1-receptorantagonister
EA200900781A1 (ru) 4-фенилпиран-3,5-дионы, 4-фенилтиопиран-3,5-дионы и циклогексантрионы, как новые гербициды
DK1638969T3 (da) CGRP-receptorantagonister
EA201100306A1 (ru) Производные циклогексиламида и их применение в качестве антагонистов рецептора crf-1
NO20083593L (no) Anti-EphrinB2-antistoffer og fremgangsmater for anvendelse av disse
EA201500316A1 (ru) Антагонисты толл-подобного рецептора 3
BRPI0814962A2 (pt) Métodos de seleção com a utilização de receptores acoplados à proteína g e composições relacionadas.
DK2197900T3 (da) Mutante dobbeltringsluttede receptorpeptider, der inhiberer beta1-adrenoreceptorantistoffer
CR10280A (es) Anticuerpos de la efgl7 y metodos de uso
ATE549350T1 (de) Neuropeptid-2-rezeptor-agonisten