ATE546422T1 - Verfahren zur herstellung von trans-2,3- disubstituierten naphthochinonen - Google Patents

Verfahren zur herstellung von trans-2,3- disubstituierten naphthochinonen

Info

Publication number
ATE546422T1
ATE546422T1 AT08750885T AT08750885T ATE546422T1 AT E546422 T1 ATE546422 T1 AT E546422T1 AT 08750885 T AT08750885 T AT 08750885T AT 08750885 T AT08750885 T AT 08750885T AT E546422 T1 ATE546422 T1 AT E546422T1
Authority
AT
Austria
Prior art keywords
naphthoquinones
disubstituted
producing trans
trans
preparation
Prior art date
Application number
AT08750885T
Other languages
English (en)
Inventor
Antonio Nardi
Mara Sada
Annibale Salvi
Stefano Maiorana
Original Assignee
Laboratorio Chimico Int Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Chimico Int Spa filed Critical Laboratorio Chimico Int Spa
Application granted granted Critical
Publication of ATE546422T1 publication Critical patent/ATE546422T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/10—Separation; Purification; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surgical Instruments (AREA)
  • Cephalosporin Compounds (AREA)
AT08750885T 2007-05-09 2008-05-06 Verfahren zur herstellung von trans-2,3- disubstituierten naphthochinonen ATE546422T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000941A ITMI20070941A1 (it) 2007-05-09 2007-05-09 Procedimento per la preparazione di naftochinoni trans2,3-disostituiti
PCT/IB2008/001110 WO2008139290A1 (en) 2007-05-09 2008-05-06 Process for the preparation oftrans-2,3-disubstituted naphthoquinones

Publications (1)

Publication Number Publication Date
ATE546422T1 true ATE546422T1 (de) 2012-03-15

Family

ID=39744902

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08750885T ATE546422T1 (de) 2007-05-09 2008-05-06 Verfahren zur herstellung von trans-2,3- disubstituierten naphthochinonen

Country Status (15)

Country Link
US (1) US7842840B2 (de)
EP (1) EP2152657B1 (de)
JP (1) JP5192541B2 (de)
CN (1) CN101687752B (de)
AT (1) ATE546422T1 (de)
CA (1) CA2685448C (de)
CY (1) CY1112784T1 (de)
DK (1) DK2152657T3 (de)
ES (1) ES2381923T3 (de)
HR (1) HRP20120219T1 (de)
IT (1) ITMI20070941A1 (de)
PL (1) PL2152657T3 (de)
PT (1) PT2152657E (de)
SI (1) SI2152657T1 (de)
WO (1) WO2008139290A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2216315A1 (de) * 2007-06-26 2010-08-11 Hetero Drugs Limited Neuartige kristalline Formen von Atovaquon
WO2010001378A1 (en) 2008-06-30 2010-01-07 Chemagis Ltd. Process for the epimerization of atovaquone isomer, atovaquone intermediates and mixture thereof
WO2012038945A2 (en) * 2010-09-23 2012-03-29 Bimeda International Pharmaceutical Limited Control of mites
CN103450141B (zh) * 2013-08-23 2015-08-26 山东鲁抗舍里乐药业有限公司 一种苯并吡喃酮类化合物、其制备方法及其应用
CN105198718A (zh) * 2015-10-27 2015-12-30 山东川成医药股份有限公司 一种布帕伐醌的制备方法
CN109715147A (zh) * 2016-06-20 2019-05-03 斯克利普斯研究院 抗疟疾组合物及其用途
CN110734368B (zh) * 2018-07-19 2022-08-12 新发药业有限公司 一种布帕伐醌的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2833537C2 (de) 1978-07-31 1981-09-17 Siemens AG, 1000 Berlin und 8000 München Kontaktbrückenanordnung
US4485117A (en) * 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
JPS5920241A (ja) * 1982-07-16 1984-02-01 ザ・ウエルカム・フアウンデ−シヨン・リミテツド タイレリア症の予防治療剤
GB8310141D0 (en) 1983-04-14 1983-05-18 Wellcome Found Naphthoquinone derivatives
DE3801743A1 (de) * 1987-07-03 1989-01-19 Bayer Ag Schaedlingsbekaempfungsmittel auf basis von substituierten 1,4-naphthochinonen und neue substituierte 1,4-naphthochinone
JP2804302B2 (ja) * 1988-08-16 1998-09-24 ザ ウエルカム フアウンデーション リミテッド 治療剤
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
JPH08109147A (ja) * 1994-10-11 1996-04-30 Dainippon Ink & Chem Inc 1,4−ジ置換−2,6−ジフルオロベンゼン誘導体
JP2004256490A (ja) * 2003-02-27 2004-09-16 Nagase Chemtex Corp トランスシクロヘキサン誘導体の製造方法

Also Published As

Publication number Publication date
DK2152657T3 (da) 2012-05-29
ITMI20070941A1 (it) 2008-11-10
US20100137644A1 (en) 2010-06-03
JP5192541B2 (ja) 2013-05-08
PL2152657T3 (pl) 2012-07-31
CA2685448A1 (en) 2008-11-20
EP2152657A1 (de) 2010-02-17
CN101687752A (zh) 2010-03-31
WO2008139290A1 (en) 2008-11-20
PT2152657E (pt) 2012-03-27
EP2152657B1 (de) 2012-02-22
US7842840B2 (en) 2010-11-30
CN101687752B (zh) 2013-01-30
ES2381923T3 (es) 2012-06-01
CA2685448C (en) 2014-11-18
CY1112784T1 (el) 2016-02-10
JP2010526131A (ja) 2010-07-29
SI2152657T1 (sl) 2012-04-30
HRP20120219T1 (hr) 2012-04-30

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