ATE546521T1 - Sesquiterpene synthasen und verwerdungsmethoden - Google Patents

Sesquiterpene synthasen und verwerdungsmethoden

Info

Publication number: ATE546521T1
Authority: AT; Austria
Prior art keywords: sesquiterpene synthases; methods; sesquiterpene; synthases; provides
Prior art date: 2002-10-04

Application number

AT03769780T

Other languages

English (en)

Inventor

Michel Schalk

Anthony Clark

Original Assignee

Firmenich & Cie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-04

Filing date

2003-10-02

Publication date

2012-03-15

2003-10-02 Application filed by Firmenich & Cie filed Critical Firmenich & Cie

2003-10-02 Priority claimed from PCT/IB2003/005072 external-priority patent/WO2004031376A2/en

2012-03-15 Application granted granted Critical

2012-03-15 Publication of ATE546521T1 publication Critical patent/ATE546521T1/de

Links

229930004725 sesquiterpene Natural products 0.000 title 1
150000004354 sesquiterpene derivatives Chemical class 0.000 title 1
101710093888 Pentalenene synthase Proteins 0.000 abstract 4
101710115850 Sesquiterpene synthase Proteins 0.000 abstract 4
VPDZRSSKICPUEY-GQRSATBHSA-N (+)-Bicyclogermacrene Natural products CC1(C)[C@@H]/2[C@H]1CC/C(/C)=C\CC/C(/C)=C\2 VPDZRSSKICPUEY-GQRSATBHSA-N 0.000 abstract 1
QEBNYNLSCGVZOH-NFAWXSAZSA-N (+)-valencene Chemical compound C1C[C@@H](C(C)=C)C[C@@]2(C)[C@H](C)CCC=C21 QEBNYNLSCGVZOH-NFAWXSAZSA-N 0.000 abstract 1
FUCYIEXQVQJBKY-ZFWWWQNUSA-N (+)-δ-Cadinene Chemical compound C1CC(C)=C[C@H]2[C@H](C(C)C)CCC(C)=C21 FUCYIEXQVQJBKY-ZFWWWQNUSA-N 0.000 abstract 1
KONGRWVLXLWGDV-BYGOPZEFSA-N (-)-cubebol Chemical compound CC(C)[C@@H]([C@H]12)CC[C@@H](C)[C@]32[C@@H]1[C@@](C)(O)CC3 KONGRWVLXLWGDV-BYGOPZEFSA-N 0.000 abstract 1
239000001890 (2R)-8,8,8a-trimethyl-2-prop-1-en-2-yl-1,2,3,4,6,7-hexahydronaphthalene Substances 0.000 abstract 1
VWFJDQUYCIWHTN-YFVJMOTDSA-N 2-trans,6-trans-farnesyl diphosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@](O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-YFVJMOTDSA-N 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
VWFJDQUYCIWHTN-UHFFFAOYSA-N Farnesyl pyrophosphate Natural products CC(C)=CCCC(C)=CCCC(C)=CCOP(O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-UHFFFAOYSA-N 0.000 abstract 1
125000001931 aliphatic group Chemical group 0.000 abstract 1
QMAYBMKBYCGXDH-UHFFFAOYSA-N alpha-amorphene Natural products C1CC(C)=CC2C(C(C)C)CC=C(C)C21 QMAYBMKBYCGXDH-UHFFFAOYSA-N 0.000 abstract 1
VPDZRSSKICPUEY-JEPMYXAXSA-N bicyclogermacrene Chemical compound C1CC(/C)=C/CC\C(C)=C\[C@@H]2C(C)(C)[C@H]12 VPDZRSSKICPUEY-JEPMYXAXSA-N 0.000 abstract 1
RXARZHLXLNWPFG-UHFFFAOYSA-N bicyclogermacrene Natural products CC1=C2C3C(CCC2=CCC1)C3(C)C RXARZHLXLNWPFG-UHFFFAOYSA-N 0.000 abstract 1
KONGRWVLXLWGDV-UHFFFAOYSA-N cubebol Natural products C12C(C(C)C)CCC(C)C32C1C(C)(O)CC3 KONGRWVLXLWGDV-UHFFFAOYSA-N 0.000 abstract 1
YOCDGWMCBBMMGJ-UHFFFAOYSA-N delta-cadinene Natural products C1C=C(C)CC2C(C(C)C)CCC(=C)C21 YOCDGWMCBBMMGJ-UHFFFAOYSA-N 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
USDOQCCMRDNVAH-UHFFFAOYSA-N sigma-cadinene Natural products C1C=C(C)CC2C(C(C)C)CC=C(C)C21 USDOQCCMRDNVAH-UHFFFAOYSA-N 0.000 abstract 1
WCTNXGFHEZQHDR-UHFFFAOYSA-N valencene Natural products C1CC(C)(C)C2(C)CC(C(=C)C)CCC2=C1 WCTNXGFHEZQHDR-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT03769780T 2002-10-04 2003-10-02 Sesquiterpene synthasen und verwerdungsmethoden ATE546521T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US41576502P	2002-10-04	2002-10-04
IB0205070		2002-12-02
PCT/IB2003/005072 WO2004031376A2 (en)	2002-10-04	2003-10-02	Sesquiterpene synthases and methods of use

Publications (1)

Publication Number	Publication Date
ATE546521T1 true ATE546521T1 (de)	2012-03-15

Family

ID=45724260

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03769780T ATE546521T1 (de)	2002-10-04	2003-10-02	Sesquiterpene synthasen und verwerdungsmethoden

Country Status (4)

Country	Link
US (2)	US7273735B2 (de)
AT (1)	ATE546521T1 (de)
BR (1)	BRPI0314979B1 (de)
ES (1)	ES2607122T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7442785B2 (en) *	2003-07-24	2008-10-28	The University Of Kentucky Research Foundation	Sesquiterpene synthase gene and protein
WO2010019696A2 (en)	2008-08-12	2010-02-18	Allylix, Inc.	Method for production of isoprenoids
ES2608480T4 (es) *	2009-10-28	2017-10-05	Fundo De Defesa Da Citricultura - Fundecitrus	Composiciones repelentes y enfoques genéticos para controlar el Huanglongbing
EP2336310A1 (de)	2009-12-16	2011-06-22	Isobionics B.V.	Valencensynthase
JP2013544084A (ja) *	2010-10-29	2013-12-12	アリリクス・インコーポレイテッド	改変されたバレンセンシンターゼポリペプチド、コーディング核酸分子およびその使用
EP2537926A1 (de)	2011-06-21	2012-12-26	Isobionics B.V.	Valencensynthase
US20150250166A1 (en)	2012-08-23	2015-09-10	Allylix, Inc.	Nootkatone as an insecticide and insect repellent
ES2891377T3 (es)	2013-03-14	2022-01-27	Evolva Inc	Polipéptidos de valenceno sintasa, moléculas de ácido nucleico codificantes y usos de los mismos
KR101735697B1 (ko)	2013-10-07	2017-05-24	서울대학교산학협력단	이종 시스템에서 (-)-α-비사보롤을 생산하는 방법
WO2015053510A1 (ko) *	2013-10-07	2015-04-16	서울대학교산학협력단	이종 시스템에서 (-)-α-비사보롤을 생산하는 방법
EP3183357B1 (de)	2014-08-21	2020-03-04	Manus Bio Inc.	Verfahren zur herstellung von oxygeniertem valencen
ES2959560T3 (es)	2015-08-21	2024-02-27	Manus Bio Inc	Aumento de la productividad de células hospedadoras de E. coli que expresan funcionalmente enzimas P450
KR102656420B1 (ko)	2017-01-26	2024-04-09	마누스 바이오, 인크.	터페노이드 생성물의 미생물 생산을 위한 대사 조작
WO2019161141A1 (en)	2018-02-14	2019-08-22	Ginkgo Bioworks	Chimeric terpene synthases
CN118108568A (zh) *	2023-03-02	2024-05-31	山东大学	一种新型二萜类化合物及其制备方法、应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3613799C1 (de) *	1986-04-24	1987-09-03	Nattermann A & Cie	Verwendung von Glycofurol zum Verfluessigen von Arzneimittelzubereitungen fuer das Abfuellen in Weichgelatinekapseln
US6306383B1 (en) *	1998-09-16	2001-10-23	Wilson T Crandall	Method for topical treatment of scars with protein kinase C inhibitors
US6979441B2 (en) *	1998-09-16	2005-12-27	Wilson T Crandall	Method for topical treatment of carpal tunnel syndrome
US6183766B1 (en) *	1999-02-12	2001-02-06	The Procter & Gamble Company	Skin sanitizing compositions
EP1541039B1 (de)	1999-03-31	2008-01-02	Firmenich Sa	Verwendung von Cubebol als Aromastoff
US7220438B2 (en) *	1999-09-23	2007-05-22	Asac Compañia de Biotecnologia	Pharmacological activities of Curcuma longa extracts
EP1231273A1 (de) *	2001-02-12	2002-08-14	Plant Research International B.V.	Terpen Synthase/Cyclase und Olefin Synthase sowie deren Verwendung
US7357950B2 (en) *	2003-03-21	2008-04-15	Elizabeth Anne Mazzio	Topical treatment for dyshidrosis (pompholyx) and dry skin disorders
AU2004269197A1 (en) *	2003-09-02	2005-03-10	State Of Israel, Ministry Of Agriculture, Agricultural Research Organization	Citrus sesquiterpene synthase, methods of production and uses thereof

2003
- 2003-10-02 BR BRPI0314979A patent/BRPI0314979B1/pt not_active IP Right Cessation
- 2003-10-02 AT AT03769780T patent/ATE546521T1/de active
- 2003-10-02 ES ES10177152.5T patent/ES2607122T3/es not_active Expired - Lifetime
2005
- 2005-03-30 US US11/094,607 patent/US7273735B2/en not_active Expired - Lifetime
2007
- 2007-08-17 US US11/840,535 patent/US7790426B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2607122T3 (es)	2017-03-29
US20080213832A1 (en)	2008-09-04
BRPI0314979B1 (pt)	2019-10-22
US20050210549A1 (en)	2005-09-22
US7273735B2 (en)	2007-09-25
US7790426B2 (en)	2010-09-07

Publication	Publication Date	Title
WO2004031376A3 (en)	2005-05-26	Sesquiterpene synthases and methods of use
ATE546521T1 (de)	2012-03-15	Sesquiterpene synthasen und verwerdungsmethoden
ATE424460T1 (de)	2009-03-15	Sesquiterpen-synthasen aus patchouli
PT1190068E (pt)	2006-06-30	Sequencias de acidos nucleicos para proteinas envolvidas na sintese de tocoferol
EA200400368A1 (ru)	2004-12-30	Новые дигидроптеридиноны, способы их получения и их применение в качестве лекарственных средств
TW200745103A (en)	2007-12-16	Substituted 7-azaindazoles, compositions containing them, production process and use
AU2001242299A1 (en)	2001-09-24	Fungal transcriptional activator useful in methods for producing polypeptides
BR0308351A (pt)	2007-04-17	molécula de ácido nucleico isolada, planta transgênica, e, métodos para produzir uma planta transgênica e para selecionar uma planta contendo uma molécula de ácido nucleico
BR0207933A (pt)	2004-03-02	Mutantes de interleucina-18, sua produção e uso
MX2007002470A (es)	2009-02-12	Fenilaminotiazoles sustituidos y su uso.
ATE365217T1 (de)	2007-07-15	Nukelinsäuresequenzen für proteine, die an der tocopherolbiosynthese beteiligt sind
WO2005040107A3 (en)	2009-02-12	Methods for making simvastatin and intermediates
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EA200300743A1 (ru)	2004-02-26	Ячмень с низкой липоксигеназной 1 активностью
DK1259593T3 (da)	2005-08-15	Tand-progenitorcelle og fremgangsmåde til frembringelse heraf
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AU2003259750A1 (en)	2004-03-03	Methods and compositions for targeting secretory lysosomes