ATE424460T1 - Sesquiterpen-synthasen aus patchouli - Google Patents
Sesquiterpen-synthasen aus patchouliInfo
- Publication number
- ATE424460T1 ATE424460T1 AT04798949T AT04798949T ATE424460T1 AT E424460 T1 ATE424460 T1 AT E424460T1 AT 04798949 T AT04798949 T AT 04798949T AT 04798949 T AT04798949 T AT 04798949T AT E424460 T1 ATE424460 T1 AT E424460T1
- Authority
- AT
- Austria
- Prior art keywords
- sesquiterpene synthases
- sesquiterpene
- patchouli
- synthases
- methods
- Prior art date
Links
- 240000002505 Pogostemon cablin Species 0.000 title abstract 3
- 235000011751 Pogostemon cablin Nutrition 0.000 title abstract 3
- 229930004725 sesquiterpene Natural products 0.000 title abstract 3
- 150000004354 sesquiterpene derivatives Chemical class 0.000 title abstract 3
- 101710093888 Pentalenene synthase Proteins 0.000 abstract 4
- 101710115850 Sesquiterpene synthase Proteins 0.000 abstract 4
- VWFJDQUYCIWHTN-YFVJMOTDSA-N 2-trans,6-trans-farnesyl diphosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@](O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-YFVJMOTDSA-N 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- VWFJDQUYCIWHTN-UHFFFAOYSA-N Farnesyl pyrophosphate Natural products CC(C)=CCCC(C)=CCCC(C)=CCOP(O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-UHFFFAOYSA-N 0.000 abstract 1
- NGIVKZGKEPRIGG-CQSZACIVSA-N gamma-curcumene Chemical compound CC(C)=CCC[C@@H](C)C1=CC=C(C)CC1 NGIVKZGKEPRIGG-CQSZACIVSA-N 0.000 abstract 1
- NGIVKZGKEPRIGG-UHFFFAOYSA-N gamma-curcumene Natural products CC(C)=CCCC(C)C1=CC=C(C)CC1 NGIVKZGKEPRIGG-UHFFFAOYSA-N 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- GGHMUJBZYLPWFD-CUZKYEQNSA-N patchouli alcohol Chemical compound C1C[C@]2(C)[C@@]3(O)CC[C@H](C)[C@@H]2C[C@@H]1C3(C)C GGHMUJBZYLPWFD-CUZKYEQNSA-N 0.000 abstract 1
- GGHMUJBZYLPWFD-UHFFFAOYSA-N rac-patchouli alcohol Natural products C1CC2(C)C3(O)CCC(C)C2CC1C3(C)C GGHMUJBZYLPWFD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52551203P | 2003-11-26 | 2003-11-26 | |
| PCT/IB2003/006459 WO2005056803A1 (en) | 2003-12-09 | 2003-12-09 | Sesquiterpene synthases from patchouli |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424460T1 true ATE424460T1 (de) | 2009-03-15 |
Family
ID=34635470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04798949T ATE424460T1 (de) | 2003-11-26 | 2004-11-19 | Sesquiterpen-synthasen aus patchouli |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7622288B2 (de) |
| EP (1) | EP1697519B1 (de) |
| JP (1) | JP4700617B2 (de) |
| CN (1) | CN1886508B (de) |
| AT (1) | ATE424460T1 (de) |
| BR (1) | BRPI0416912B1 (de) |
| DE (1) | DE602004019811D1 (de) |
| IL (1) | IL175728A (de) |
| RU (1) | RU2006122534A (de) |
| WO (1) | WO2005052163A2 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8017835B2 (en) | 2005-04-19 | 2011-09-13 | University Of Kentucky Research Foundation | Transformed plants accumulating terpenes |
| ATE486133T1 (de) * | 2005-07-01 | 2010-11-15 | Univ Kentucky Res Found | Transformierte pflanzen mit anreicherung von mono-und/oder sesquiterpenen |
| WO2008100251A1 (en) * | 2007-02-13 | 2008-08-21 | Ls9, Inc. | Modified microorganism uses therefor |
| DE602007008067D1 (de) | 2006-02-14 | 2010-09-09 | Firmenich & Cie | Verfahren zur herstellung von terpenen und mep-transformierte mikroorganismen dafür |
| US8110670B2 (en) | 2006-05-19 | 2012-02-07 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
| US20100242345A1 (en) | 2006-05-19 | 2010-09-30 | LS9, Inc | Production of fatty acids & derivatives thereof |
| US7399323B2 (en) | 2006-10-10 | 2008-07-15 | Amyris Biotechnologies, Inc. | Fuel compositions comprising farnesane and farnesane derivatives and method of making and using same |
| EP2425007A4 (de) | 2009-04-27 | 2013-01-02 | Ls9 Inc | Herstellung von fettsäureestern |
| WO2011141855A1 (en) | 2010-05-10 | 2011-11-17 | Firmenich Sa | Method for producing patchoulol and 7 - epi - alpha - slinene |
| US10053703B2 (en) * | 2013-06-28 | 2018-08-21 | University Of Copenhagen | Heterologous production of patchoulol, β-santalene, and sclareol in moss cells |
| CN103352034A (zh) * | 2013-07-12 | 2013-10-16 | 中国医学科学院药用植物研究所 | 沉香倍半萜合酶蛋白ass4及其编码基因和应用 |
| CN105579585B (zh) * | 2013-09-05 | 2019-03-15 | 国立大学法人新潟大学 | 龙涎香醇的制造方法 |
| GB201516911D0 (en) * | 2015-09-24 | 2015-11-11 | Givaudan Sa | Perfume compositions |
| US11421199B2 (en) * | 2016-11-04 | 2022-08-23 | Tianjin Institute Of Industrial Biotechnology, Chinese Academy Of Sciences | Recombinant yeast and use thereof |
| NL2019473B1 (en) * | 2017-09-01 | 2019-03-11 | Isobionics B V | Terpene Synthase producing patchoulol and elemol, and preferably also pogostol |
| EP3495489A1 (de) | 2017-12-05 | 2019-06-12 | Givaudan SA | Produktion von guaiene und rotundon |
| WO2019161141A1 (en) | 2018-02-14 | 2019-08-22 | Ginkgo Bioworks | Chimeric terpene synthases |
| CN109735523B (zh) * | 2019-02-02 | 2022-08-30 | 中国科学院昆明植物研究所 | 雪松醇合酶Lc-CedS编码基因及其应用 |
| CN114107233B (zh) * | 2021-10-27 | 2024-01-09 | 武汉合生科技有限公司 | 佛术烯的合成酶基因和高产菌株以及用途 |
| CN116574718B (zh) * | 2023-06-09 | 2024-04-16 | 中国中医科学院中药研究所 | SoSTPS2在作为倍半萜合酶中的应用 |
| CN117987434B (zh) * | 2024-04-07 | 2024-06-21 | 北京未名拾光生物技术有限公司 | 广藿香醇合酶编码基因及其表达体系 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ503985A (en) | 1997-10-06 | 2001-06-29 | Univ Washington | Isolation and expression of farnesene synthase from peppermint, mentha X piperita, L. |
| AU2490399A (en) | 1998-02-02 | 1999-08-16 | Regents Of The University Of California, The | Germacrene c synthase gene of (lycopersicon esculentum) |
| AR022383A1 (es) * | 1998-09-18 | 2002-09-04 | Univ Kentucky Res Found | Sintasas |
| AU3810300A (en) | 1999-03-12 | 2000-10-04 | Research Institute For Agrobiology And Soil Fertility (Ab-Dl O) | Sesquiterpenoid synthase genes and their use for influencing bitterness and resistance in plants |
| EP1231273A1 (de) * | 2001-02-12 | 2002-08-14 | Plant Research International B.V. | Terpen Synthase/Cyclase und Olefin Synthase sowie deren Verwendung |
| JP2005503163A (ja) | 2001-09-17 | 2005-02-03 | プラント リサーチ インターナショナル ビー. ブイ. | 生物的転化のための植物酵素 |
-
2004
- 2004-11-19 DE DE602004019811T patent/DE602004019811D1/de not_active Expired - Lifetime
- 2004-11-19 WO PCT/IB2004/003836 patent/WO2005052163A2/en not_active Ceased
- 2004-11-19 EP EP04798949A patent/EP1697519B1/de not_active Expired - Lifetime
- 2004-11-19 AT AT04798949T patent/ATE424460T1/de not_active IP Right Cessation
- 2004-11-19 RU RU2006122534/13A patent/RU2006122534A/ru not_active Application Discontinuation
- 2004-11-19 BR BRPI0416912A patent/BRPI0416912B1/pt active IP Right Grant
- 2004-11-19 JP JP2006540658A patent/JP4700617B2/ja not_active Expired - Lifetime
- 2004-11-19 CN CN2004800350480A patent/CN1886508B/zh not_active Expired - Lifetime
-
2006
- 2006-05-17 IL IL175728A patent/IL175728A/en active IP Right Grant
- 2006-05-23 US US11/440,105 patent/US7622288B2/en not_active Expired - Lifetime
-
2009
- 2009-02-05 US US12/366,573 patent/US8058046B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20090205060A1 (en) | 2009-08-13 |
| WO2005052163A3 (en) | 2005-12-01 |
| EP1697519B1 (de) | 2009-03-04 |
| EP1697519A2 (de) | 2006-09-06 |
| JP4700617B2 (ja) | 2011-06-15 |
| JP2007514416A (ja) | 2007-06-07 |
| BRPI0416912B1 (pt) | 2020-01-28 |
| US20060206957A1 (en) | 2006-09-14 |
| WO2005052163A2 (en) | 2005-06-09 |
| CN1886508A (zh) | 2006-12-27 |
| RU2006122534A (ru) | 2008-01-10 |
| IL175728A0 (en) | 2006-09-05 |
| IL175728A (en) | 2011-05-31 |
| HK1094456A1 (en) | 2007-03-30 |
| DE602004019811D1 (de) | 2009-04-16 |
| US8058046B2 (en) | 2011-11-15 |
| BRPI0416912A (pt) | 2007-01-16 |
| CN1886508B (zh) | 2012-07-18 |
| US7622288B2 (en) | 2009-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |