ATE424460T1 - Sesquiterpen-synthasen aus patchouli - Google Patents

Sesquiterpen-synthasen aus patchouli

Info

Publication number: ATE424460T1
Authority: AT; Austria
Prior art keywords: sesquiterpene synthases; sesquiterpene; patchouli; synthases; methods
Prior art date: 2003-11-26

Application number

AT04798949T

Other languages

English (en)

Inventor

Michel Schalk

Fabienne Deguerry

Original Assignee

Firmenich & Cie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-11-26

Filing date

2004-11-19

Publication date

2009-03-15

2003-12-09 Priority claimed from PCT/IB2003/006459 external-priority patent/WO2005056803A1/en

2004-11-19 Application filed by Firmenich & Cie filed Critical Firmenich & Cie

2009-03-15 Application granted granted Critical

2009-03-15 Publication of ATE424460T1 publication Critical patent/ATE424460T1/de

Links

240000002505 Pogostemon cablin Species 0.000 title abstract 3
235000011751 Pogostemon cablin Nutrition 0.000 title abstract 3
229930004725 sesquiterpene Natural products 0.000 title abstract 3
150000004354 sesquiterpene derivatives Chemical class 0.000 title abstract 3
101710093888 Pentalenene synthase Proteins 0.000 abstract 4
101710115850 Sesquiterpene synthase Proteins 0.000 abstract 4
VWFJDQUYCIWHTN-YFVJMOTDSA-N 2-trans,6-trans-farnesyl diphosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@](O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-YFVJMOTDSA-N 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
VWFJDQUYCIWHTN-UHFFFAOYSA-N Farnesyl pyrophosphate Natural products CC(C)=CCCC(C)=CCCC(C)=CCOP(O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-UHFFFAOYSA-N 0.000 abstract 1
NGIVKZGKEPRIGG-CQSZACIVSA-N gamma-curcumene Chemical compound CC(C)=CCC[C@@H](C)C1=CC=C(C)CC1 NGIVKZGKEPRIGG-CQSZACIVSA-N 0.000 abstract 1
NGIVKZGKEPRIGG-UHFFFAOYSA-N gamma-curcumene Natural products CC(C)=CCCC(C)C1=CC=C(C)CC1 NGIVKZGKEPRIGG-UHFFFAOYSA-N 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
GGHMUJBZYLPWFD-CUZKYEQNSA-N patchouli alcohol Chemical compound C1C[C@]2(C)[C@@]3(O)CC[C@H](C)[C@@H]2C[C@@H]1C3(C)C GGHMUJBZYLPWFD-CUZKYEQNSA-N 0.000 abstract 1
GGHMUJBZYLPWFD-UHFFFAOYSA-N rac-patchouli alcohol Natural products C1CC2(C)C3(O)CCC(C)C2CC1C3(C)C GGHMUJBZYLPWFD-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)

AT04798949T 2003-11-26 2004-11-19 Sesquiterpen-synthasen aus patchouli ATE424460T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US52551203P	2003-11-26	2003-11-26
PCT/IB2003/006459 WO2005056803A1 (en)	2003-12-09	2003-12-09	Sesquiterpene synthases from patchouli

Publications (1)

Publication Number	Publication Date
ATE424460T1 true ATE424460T1 (de)	2009-03-15

Family

ID=34635470

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04798949T ATE424460T1 (de)	2003-11-26	2004-11-19	Sesquiterpen-synthasen aus patchouli

Country Status (10)

Country	Link
US (2)	US7622288B2 (de)
EP (1)	EP1697519B1 (de)
JP (1)	JP4700617B2 (de)
CN (1)	CN1886508B (de)
AT (1)	ATE424460T1 (de)
BR (1)	BRPI0416912B1 (de)
DE (1)	DE602004019811D1 (de)
IL (1)	IL175728A (de)
RU (1)	RU2006122534A (de)
WO (1)	WO2005052163A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101163795B (zh)	2005-04-19	2014-04-23	肯塔基大学研究机构	积聚萜的转化的植物
US20080201796A1 (en) *	2005-07-01	2008-08-21	University Of Kentucky Research Foundation	Transformed plants accumulating mono-and/or sesquiterpenes
WO2008100251A1 (en) *	2007-02-13	2008-08-21	Ls9, Inc.	Modified microorganism uses therefor
EP1987147B1 (de)	2006-02-14	2010-07-28	Firmenich S.A.	Verfahren zur herstellung von terpenen und mep-transformierte mikroorganismen dafür
US8110670B2 (en)	2006-05-19	2012-02-07	Ls9, Inc.	Enhanced production of fatty acid derivatives
US20100242345A1 (en)	2006-05-19	2010-09-30	LS9, Inc	Production of fatty acids & derivatives thereof
US7846222B2 (en) *	2006-10-10	2010-12-07	Amyris Biotechnologies, Inc.	Fuel compositions comprising farnesane and farnesane derivatives and method of making and using same
EP2425007A4 (de)	2009-04-27	2013-01-02	Ls9 Inc	Herstellung von fettsäureestern
EP2569427B1 (de)	2010-05-10	2017-11-08	Firmenich SA	Verfahren zur Herstellung von patchoulol and 7-epi-alpha-selinene
WO2014206412A1 (en) *	2013-06-28	2014-12-31	Københavns Universitet	Heterologous production of patchoulol, beta-santalene, and sclareol in moss cells
CN103352034A (zh) *	2013-07-12	2013-10-16	中国医学科学院药用植物研究所	沉香倍半萜合酶蛋白ass4及其编码基因和应用
JP6429243B2 (ja) *	2013-09-05	2018-11-28	国立大学法人新潟大学	アンブレインの製造方法
GB201516911D0 (en) *	2015-09-24	2015-11-11	Givaudan Sa	Perfume compositions
JP7129990B2 (ja) *	2016-11-04	2022-09-02	中国科学院天津工業生物技術研究所	組換え酵母及びその使用
NL2019473B1 (en)	2017-09-01	2019-03-11	Isobionics B V	Terpene Synthase producing patchoulol and elemol, and preferably also pogostol
EP3495489A1 (de)	2017-12-05	2019-06-12	Givaudan SA	Produktion von guaiene und rotundon
WO2019161141A1 (en)	2018-02-14	2019-08-22	Ginkgo Bioworks	Chimeric terpene synthases
CN109735523B (zh) *	2019-02-02	2022-08-30	中国科学院昆明植物研究所	雪松醇合酶Lc-CedS编码基因及其应用
CN114107233B (zh) *	2021-10-27	2024-01-09	武汉合生科技有限公司	佛术烯的合成酶基因和高产菌株以及用途
CN116574718B (zh) *	2023-06-09	2024-04-16	中国中医科学院中药研究所	SoSTPS2在作为倍半萜合酶中的应用
CN117987434B (zh) *	2024-04-07	2024-06-21	北京未名拾光生物技术有限公司	广藿香醇合酶编码基因及其表达体系

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU747746B2 (en)	1997-10-06	2002-05-23	Washington State University Research Foundation	Isolation and expression of farnesene synthase from peppermint, mentha x piperita, L.
WO1999038957A1 (en)	1998-02-02	1999-08-05	Washington State University Research Foundation	GERMACRENE C SYNTHASE GENE OF $i(LYCOPERSICON ESCULENTUM)
AR022383A1 (es) *	1998-09-18	2002-09-04	Univ Kentucky Res Found	Sintasas
AU3810300A (en)	1999-03-12	2000-10-04	Research Institute For Agrobiology And Soil Fertility (Ab-Dl O)	Sesquiterpenoid synthase genes and their use for influencing bitterness and resistance in plants
EP1231273A1 (de) *	2001-02-12	2002-08-14	Plant Research International B.V.	Terpen Synthase/Cyclase und Olefin Synthase sowie deren Verwendung
CN1589327A (zh)	2001-09-17	2005-03-02	植物研究国际公司	用于生物转化的植物酶

2004
- 2004-11-19 DE DE602004019811T patent/DE602004019811D1/de not_active Expired - Lifetime
- 2004-11-19 RU RU2006122534/13A patent/RU2006122534A/ru not_active Application Discontinuation
- 2004-11-19 AT AT04798949T patent/ATE424460T1/de not_active IP Right Cessation
- 2004-11-19 WO PCT/IB2004/003836 patent/WO2005052163A2/en not_active Ceased
- 2004-11-19 JP JP2006540658A patent/JP4700617B2/ja not_active Expired - Lifetime
- 2004-11-19 BR BRPI0416912A patent/BRPI0416912B1/pt active IP Right Grant
- 2004-11-19 EP EP04798949A patent/EP1697519B1/de not_active Expired - Lifetime
- 2004-11-19 CN CN2004800350480A patent/CN1886508B/zh not_active Expired - Lifetime
2006
- 2006-05-17 IL IL175728A patent/IL175728A/en active IP Right Grant
- 2006-05-23 US US11/440,105 patent/US7622288B2/en not_active Expired - Lifetime
2009
- 2009-02-05 US US12/366,573 patent/US8058046B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE602004019811D1 (de)	2009-04-16
HK1094456A1 (en)	2007-03-30
JP4700617B2 (ja)	2011-06-15
WO2005052163A3 (en)	2005-12-01
WO2005052163A2 (en)	2005-06-09
CN1886508B (zh)	2012-07-18
US7622288B2 (en)	2009-11-24
BRPI0416912B1 (pt)	2020-01-28
IL175728A (en)	2011-05-31
RU2006122534A (ru)	2008-01-10
US8058046B2 (en)	2011-11-15
US20090205060A1 (en)	2009-08-13
IL175728A0 (en)	2006-09-05
JP2007514416A (ja)	2007-06-07
CN1886508A (zh)	2006-12-27
EP1697519B1 (de)	2009-03-04
US20060206957A1 (en)	2006-09-14
EP1697519A2 (de)	2006-09-06
BRPI0416912A (pt)	2007-01-16

Legal Events

Date	Code	Title	Description
2009-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE602004019811D1 (de)	2009-04-16	Sesquiterpen-synthasen aus patchouli
ATE546521T1 (de)	2012-03-15	Sesquiterpene synthasen und verwerdungsmethoden
WO2005047505A3 (en)	2008-01-03	Methods and products for expression of micro rnas
AR056256A1 (es)	2007-10-03	Plantas resistentes al estres
PT1190068E (pt)	2006-06-30	Sequencias de acidos nucleicos para proteinas envolvidas na sintese de tocoferol
BR0308351A (pt)	2007-04-17	molécula de ácido nucleico isolada, planta transgênica, e, métodos para produzir uma planta transgênica e para selecionar uma planta contendo uma molécula de ácido nucleico
WO2005035769A3 (en)	2005-06-02	Gene silencing by using micro-rna molecules
WO2004001000A3 (en)	2004-08-12	Intron double stranded rna constructs and uses thereof
IN2012DN00403A (de)	2015-08-21
MXPA05005108A (es)	2005-11-24	Composiciones con ciclopropenos y auxiliares.
CL2010001372A1 (es)	2011-05-13	Procedimiento para la produccion de frutooligosacaridos a partir de sacarosa que comprende contactar la sacarosa con una enzima no inmivilizada con actividad inulinasa y/o fructosil transferasa.
WO2004055117A3 (de)	2004-08-19	Carboxamid-substituierte farbstoffe für analytische anwendungen
WO2008021574A8 (en)	2009-07-23	Modulating plant carotenoid levels
AU5354301A (en)	2001-10-30	Nucleic acid sequences to proteins involved in tocopherol synthesis
WO2006091924A3 (en)	2006-11-09	Producing carotenoids
NZ583299A (en)	2012-09-28	Modification of lignin biosynthesis via sense suppression
WO2005054439A3 (en)	2006-05-11	Small interfering rna (sirna)-mediated heritable gene manipulation in plants
WO2003042217A3 (en)	2003-10-02	Method for making epothilone compounds by bioconversion with microorganisms
WO2004090121A3 (en)	2004-12-29	Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
WO2004067705A3 (en)	2004-12-02	Stable lipase variants
WO2006046076A3 (en)	2006-09-08	Applications of isolated nucleic acid fragments comprising cpg islands
WO2005089471A3 (en)	2007-08-23	Increased stress tolerance and enhanced yield in plants
WO2004056848A3 (en)	2005-07-28	Elevation of oil levels in brassica plants
AU2001277648A1 (en)	2002-04-15	Plant cyclin-dependent kinase inhibitors
WO2007004104A3 (en)	2007-07-26	Transformed plants accumulating mono- and/or sesquiterpenes