ATE546531T1 - Transaktivierungssystem für säugerzellen - Google Patents

Transaktivierungssystem für säugerzellen

Info

Publication number
ATE546531T1
ATE546531T1 AT04815827T AT04815827T ATE546531T1 AT E546531 T1 ATE546531 T1 AT E546531T1 AT 04815827 T AT04815827 T AT 04815827T AT 04815827 T AT04815827 T AT 04815827T AT E546531 T1 ATE546531 T1 AT E546531T1
Authority
AT
Austria
Prior art keywords
mammal cells
methods
host cell
desired polypeptide
transactivation system
Prior art date
Application number
AT04815827T
Other languages
English (en)
Inventor
Christopher Bebbington
Bo Yu
Original Assignee
Kalobios Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kalobios Inc filed Critical Kalobios Inc
Application granted granted Critical
Publication of ATE546531T1 publication Critical patent/ATE546531T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04815827T 2003-12-31 2004-12-30 Transaktivierungssystem für säugerzellen ATE546531T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53391703P 2003-12-31 2003-12-31
PCT/US2004/043830 WO2005065348A2 (en) 2003-12-31 2004-12-30 Transactivation system for mammalian cells

Publications (1)

Publication Number Publication Date
ATE546531T1 true ATE546531T1 (de) 2012-03-15

Family

ID=34748979

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04815827T ATE546531T1 (de) 2003-12-31 2004-12-30 Transaktivierungssystem für säugerzellen

Country Status (4)

Country Link
US (1) US8354251B2 (de)
EP (1) EP1702071B1 (de)
AT (1) ATE546531T1 (de)
WO (1) WO2005065348A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7537930B2 (en) 2004-07-23 2009-05-26 Immunomedics, Inc. Mammalian cell lines for increasing longevity and protein yield from a cell culture
KR100959456B1 (ko) * 2004-11-18 2010-05-25 고쿠리츠다이가쿠호진 히로시마다이가쿠 유전자 증폭에 의해 형성된 반복서열로부터, 발현이 억제된단백질을 발현시키는 방법, 키트, 및 형질전환체
US20090215165A1 (en) 2005-05-20 2009-08-27 James Rance High-level expression of recombinant antibody in a mammalian host cell
US8357781B2 (en) 2006-06-01 2013-01-22 Janssen Alzheimer Immunotherapy Neuroactive fragments of APP
WO2008085962A2 (en) * 2007-01-08 2008-07-17 Millipore Corporation Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
MX355650B (es) 2009-08-11 2018-04-26 Genentech Inc Produccion de proteinas en medios de cultivo de celulas libres de glutamina.
WO2011103490A2 (en) 2010-02-18 2011-08-25 The Regents Of The University Of California INTEGRIN αVβ8 NEUTRALIZING ANTIBODY
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) * 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (de) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogene genexpression eines therapeutischen adenovirus mit geringem einfluss auf die virale kinetik
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
WO2020223160A1 (en) * 2019-04-30 2020-11-05 Chan Zuckerberg Biohub, Inc. A novel chromatin-opening element for stable long term gene expression

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8900483D0 (en) 1989-01-10 1989-03-08 Celltech Ltd Recombinant dna method
US6274341B1 (en) 1997-10-09 2001-08-14 James E. Bailey Cytostatic process increases the productivity of cultured cells
WO2000005393A2 (en) * 1998-07-21 2000-02-03 Cobra Therapeutics Limited A polynucleotide comprising a ubiquitous chromatin opening element (ucoe)
ES2375266T3 (es) * 1998-07-21 2012-02-28 Millipore Corporation Un polinucleótido que comprende un elemento de apertura de cromatina ubicuo (ucoe).
US6780639B1 (en) * 1999-08-24 2004-08-24 Universite Libre De Bruxelles Antibiotic inducible/repressible genetic construct for gene therapy or gene immunization
AU2001259759A1 (en) * 2000-05-12 2001-11-26 Erik A. Whitehorn Methods and compositions for amplifying intracellular signal transduction
JP4435563B2 (ja) 2001-07-10 2010-03-17 バイオジェン アイデック インク アポトーシスプロセスの阻害および細胞性能の改善

Also Published As

Publication number Publication date
US20090111144A1 (en) 2009-04-30
WO2005065348A3 (en) 2005-10-27
EP1702071A4 (de) 2007-07-25
EP1702071A2 (de) 2006-09-20
WO2005065348A2 (en) 2005-07-21
US8354251B2 (en) 2013-01-15
EP1702071B1 (de) 2012-02-22

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