ATE54665T1 - Hydantoin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

Hydantoin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number: ATE54665T1
Authority: AT; Austria
Prior art keywords: hydantoin derivatives; pharmaceutical compositions; compositions containing; manufacture; salts
Prior art date: 1985-02-26

Application number

AT86102476T

Other languages

English (en)

Inventor

Kouichiro Ueda

Keiichi Nomura

Satoru Tanaka

Noboru Nakai

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-02-26

Filing date

1986-02-26

Publication date

1990-08-15

1986-02-26 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

1990-08-15 Application granted granted Critical

1990-08-15 Publication of ATE54665T1 publication Critical patent/ATE54665T1/de

Links

229940053195 antiepileptics hydantoin derivative Drugs 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical class O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
150000001469 hydantoins Chemical class 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
230000001684 chronic effect Effects 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
208000024891 symptom Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Diabetes (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT86102476T 1985-02-26 1986-02-26 Hydantoin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. ATE54665T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP60035236A JPH0772190B2 (ja)	1985-02-26	1985-02-26	ヒダントイン誘導体
EP86102476A EP0193855B1 (de)	1985-02-26	1986-02-26	Hydantoin-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number	Publication Date
ATE54665T1 true ATE54665T1 (de)	1990-08-15

Family

ID=12436204

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86102476T ATE54665T1 (de)	1985-02-26	1986-02-26	Hydantoin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (4)

Country	Link
EP (1)	EP0193855B1 (de)
JP (1)	JPH0772190B2 (de)
AT (1)	ATE54665T1 (de)
DE (1)	DE3672628D1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS63126881A (ja) *	1986-11-14	1988-05-30	Sanwa Kagaku Kenkyusho Co Ltd	ヒダントイン誘導体、その塩、これらの製法並びに該化合物を有効成分とする糖尿病合併症の予防及び治療剤
EP0264586B1 (de) *	1986-08-28	1991-04-03	Sanwa Kagaku Kenkyusho Co., Ltd.	Hydantoin-Derivate zur Behandlung von Komplikationen bei Diabetes
EA201991341A1 (ru)	2016-12-06	2019-12-30	Топикал Инновэйшнс Б.В.	Фенитоин для местного применения для лечения периферической нейропатической боли
WO2018106108A1 (en)	2016-12-06	2018-06-14	KEPPEL HESSELING, Jan Marius	Topical pharmaceutical composition containing phenytoin and a (co -)an algesic for the treatment of chronic pain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4248882A (en) *	1980-02-12	1981-02-03	Pfizer Inc.	Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) *	1980-07-21	1982-03-13	Eisai Co Ltd	Hydantoin derivative and its preparation
US4464385A (en) *	1982-04-15	1984-08-07	Alcon Laboratories, Inc.	Treatment of diabetic complications with hydantoins

1985
- 1985-02-26 JP JP60035236A patent/JPH0772190B2/ja not_active Expired - Lifetime
1986
- 1986-02-26 DE DE8686102476T patent/DE3672628D1/de not_active Expired - Fee Related
- 1986-02-26 EP EP86102476A patent/EP0193855B1/de not_active Expired - Lifetime
- 1986-02-26 AT AT86102476T patent/ATE54665T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0193855A1 (de)	1986-09-10
DE3672628D1 (de)	1990-08-23
JPH0772190B2 (ja)	1995-08-02
EP0193855B1 (de)	1990-07-18
JPS61197581A (ja)	1986-09-01

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Legal Events

Date	Code	Title	Description
1991-01-15	UEP	Publication of translation of european patent specification
1993-11-15	REN	Ceased due to non-payment of the annual fee