DK562488D0 - Farmaceutisk praeparat indeholdende polyminderivater, samt nogle af disse polyaminderivater - Google Patents

Farmaceutisk praeparat indeholdende polyminderivater, samt nogle af disse polyaminderivater

Info

Publication number: DK562488D0
Authority: DK; Denmark
Prior art keywords: derivatives; polyamine; pharmaceutical preparation; preparation containing; hydrogen
Prior art date: 1987-10-08

Application number

DK562488A

Other languages

English (en)

Other versions

DK562488A (da

Inventor

Nellikunja J Prakash

David M Stemerick

Michael L Edwards

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-08

Filing date

1988-10-07

Publication date

1988-10-07

1988-10-07 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1988-10-07 Publication of DK562488D0 publication Critical patent/DK562488D0/da

1989-04-09 Publication of DK562488A publication Critical patent/DK562488A/da

Links

229920000768 polyamine Polymers 0.000 title abstract 2
239000000825 pharmaceutical preparation Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
229940100534 Polyamine oxidase inhibitor Drugs 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
230000001613 neoplastic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Oncology (AREA)
Hematology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK562488A 1987-10-08 1988-10-07 Farmaceutisk praeparat indeholdende polyminderivater, samt nogle af disse polyaminderivater DK562488A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10619787A	1987-10-08	1987-10-08

Publications (2)

Publication Number	Publication Date
DK562488D0 true DK562488D0 (da)	1988-10-07
DK562488A DK562488A (da)	1989-04-09

Family

ID=22310050

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK562488A DK562488A (da)	1987-10-08	1988-10-07	Farmaceutisk praeparat indeholdende polyminderivater, samt nogle af disse polyaminderivater

Country Status (10)

Country	Link
EP (1)	EP0311068B1 (da)
JP (1)	JPH01128962A (da)
KR (1)	KR0130977B1 (da)
AT (1)	ATE103585T1 (da)
AU (1)	AU608373B2 (da)
DE (1)	DE3888778T2 (da)
DK (1)	DK562488A (da)
ES (1)	ES2053668T3 (da)
IE (1)	IE61846B1 (da)
ZA (1)	ZA887410B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5091576A (en) *	1986-12-02	1992-02-25	University Of Florida	Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
US5753714A (en) *	1987-02-03	1998-05-19	Merrell Pharmaceuticals Inc.	Polyamine derivatives
AU602186B2 (en) *	1987-02-03	1990-10-04	Merrell Dow Pharmaceuticals Inc.	Novel polyamine derivatives
US5109024A (en) *	1987-02-03	1992-04-28	Merrell Dow Pharmaceuticals Inc.	Polyamine derivatives as antineoplastic agents
EP0378146B1 (en) *	1989-01-10	1995-03-29	Merrell Pharmaceuticals Inc.	Polyamine derivatives as antineoplastic agents
US5561136A (en) *	1990-12-13	1996-10-01	Merrell Pharmaceuticals Inc.	Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent
US5354782A (en) *	1991-01-17	1994-10-11	Merrell Dow Pharmaceuticals Inc.	Polyamine phenols as radioprotective agents
US5217964A (en) *	1991-01-23	1993-06-08	Merrell Dow Pharmaceuticals Inc.	Polyamine thiols as radioprotective agents
EP0686142B1 (en) *	1993-02-23	1998-12-30	Merrell Pharmaceuticals Inc.	Polyamine derivatives as radioprotective agents
AU7723794A (en) *	1993-10-07	1995-05-01	Merrell Dow Pharmaceuticals Inc.	Novel process for preparing polyamine derivatives and intermediates thereof
EP0955044B1 (en) *	1995-06-26	2005-11-16	Chelator LLC	Method of inhibiting bacterial or fungal growth using a complexing agent
WO2003013245A1 (en)	2001-08-07	2003-02-20	Wisconsin Alumni Research Foundation	Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
EP1940773B1 (en) *	2005-08-10	2015-03-18	Johns Hopkins University	Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
US8318980B2 (en) *	2007-09-18	2012-11-27	Fujifilm Manufacturing Europe B.V.	UV absorbing compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57192340A (en) *	1981-05-18	1982-11-26	Nisshin Flour Milling Co Ltd	Isoprenylamine derivative
US4507321A (en) *	1982-02-17	1985-03-26	The Research Foundation Of State University Of New York	Epithelial cell growth regulating composition containing polyamines and a method of using same
ZA853602B (en) *	1984-05-17	1985-12-24	Merrell Dow Pharma	Method for the treatment of neoplasms
NZ212053A (en) *	1984-05-17	1988-02-29	Merrell Dow Pharma	Polyamine containing pharmaceutical compositions for treating neoplasms
GB8419103D0 (en) *	1984-07-26	1984-08-30	Beecham Wuelfing Gmbh & Co Kg	Compounds
CA1305425C (en) *	1986-12-02	1992-07-21	Raymond J. Bergeron	Anti-neoplastic spermine derivative
AU602186B2 (en) *	1987-02-03	1990-10-04	Merrell Dow Pharmaceuticals Inc.	Novel polyamine derivatives

1988
- 1988-10-03 ZA ZA887410A patent/ZA887410B/xx unknown
- 1988-10-05 AU AU23470/88A patent/AU608373B2/en not_active Ceased
- 1988-10-06 DE DE3888778T patent/DE3888778T2/de not_active Expired - Fee Related
- 1988-10-06 EP EP88116541A patent/EP0311068B1/en not_active Expired - Lifetime
- 1988-10-06 AT AT88116541T patent/ATE103585T1/de not_active IP Right Cessation
- 1988-10-06 ES ES88116541T patent/ES2053668T3/es not_active Expired - Lifetime
- 1988-10-07 IE IE304888A patent/IE61846B1/en not_active IP Right Cessation
- 1988-10-07 JP JP63252234A patent/JPH01128962A/ja active Pending
- 1988-10-07 DK DK562488A patent/DK562488A/da not_active Application Discontinuation
- 1988-10-08 KR KR1019880013171A patent/KR0130977B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IE61846B1 (en)	1994-11-30
KR890006228A (ko)	1989-06-12
EP0311068A2 (en)	1989-04-12
KR0130977B1 (ko)	1998-04-16
ZA887410B (en)	1989-06-28
JPH01128962A (ja)	1989-05-22
ATE103585T1 (de)	1994-04-15
IE883048L (en)	1989-04-08
DE3888778D1 (de)	1994-05-05
DK562488A (da)	1989-04-09
EP0311068B1 (en)	1994-03-30
DE3888778T2 (de)	1994-07-14
AU608373B2 (en)	1991-03-28
EP0311068A3 (en)	1990-06-13
ES2053668T3 (es)	1994-08-01
AU2347088A (en)	1989-04-13

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Legal Events

Date	Code	Title	Description
2004-08-23	AHS	Application shelved for other reasons than non-payment