ATE549345T1 - Verfahren zur herstellung von medrogeston - Google Patents
Verfahren zur herstellung von medrogestonInfo
- Publication number
- ATE549345T1 ATE549345T1 AT06700710T AT06700710T ATE549345T1 AT E549345 T1 ATE549345 T1 AT E549345T1 AT 06700710 T AT06700710 T AT 06700710T AT 06700710 T AT06700710 T AT 06700710T AT E549345 T1 ATE549345 T1 AT E549345T1
- Authority
- AT
- Austria
- Prior art keywords
- medrogeston
- producing
- methylenepregn
- medrogestone
- heterogeneously
- Prior art date
Links
- HCFSGRMEEXUOSS-JXEXPEPMSA-N medrogestone Chemical compound C1=C(C)C2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(C)[C@@]1(C)CC2 HCFSGRMEEXUOSS-JXEXPEPMSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- YTWFCLJUEASIGS-JXEXPEPMSA-N (8r,9s,10r,13s,14s,17s)-17-acetyl-10,13,17-trimethyl-6-methylidene-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C1C(=C)C2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(C)[C@@]1(C)CC2 YTWFCLJUEASIGS-JXEXPEPMSA-N 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 229960000606 medrogestone Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64405305P | 2005-01-18 | 2005-01-18 | |
| EP05100267 | 2005-01-18 | ||
| PCT/EP2006/050242 WO2006077209A1 (en) | 2005-01-18 | 2006-01-17 | Method for preparing medrogestone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE549345T1 true ATE549345T1 (de) | 2012-03-15 |
Family
ID=34938526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06700710T ATE549345T1 (de) | 2005-01-18 | 2006-01-17 | Verfahren zur herstellung von medrogeston |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1841778B1 (de) |
| JP (1) | JP2008527022A (de) |
| AT (1) | ATE549345T1 (de) |
| CA (1) | CA2595317A1 (de) |
| WO (1) | WO2006077209A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2709631T3 (pl) | 2011-05-20 | 2017-07-31 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Antagoniści receptora cb1 |
| ES2621528T3 (es) | 2012-11-28 | 2017-07-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Derivados de 3-(4-sustituido)-bencil éter de pregnenolona |
| HU231125B1 (hu) * | 2016-12-16 | 2020-12-28 | Richter Gedeon Nyrt. | Ipari eljárás Nomegesztrol-acetát előállítására |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3170936A (en) * | 1963-08-07 | 1965-02-23 | American Home Prod | Process for the preparation of 6, 17alpha-dimethyl-4, 6-pregnadiene-3, 20-dione |
| US3479342A (en) * | 1965-03-25 | 1969-11-18 | Smithkline Corp | 6,6-ethylene pregnenes |
| DE3204281C1 (de) * | 1982-02-05 | 1983-07-21 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 6-Methyl-delta?-3-ketosteroiden |
| US5428151A (en) * | 1994-05-05 | 1995-06-27 | American Home Products Corporation | Medrogestrone production |
-
2006
- 2006-01-17 EP EP06700710A patent/EP1841778B1/de not_active Expired - Lifetime
- 2006-01-17 CA CA002595317A patent/CA2595317A1/en not_active Abandoned
- 2006-01-17 AT AT06700710T patent/ATE549345T1/de active
- 2006-01-17 WO PCT/EP2006/050242 patent/WO2006077209A1/en not_active Ceased
- 2006-01-17 JP JP2007551664A patent/JP2008527022A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006077209A1 (en) | 2006-07-27 |
| CA2595317A1 (en) | 2006-07-27 |
| EP1841778A1 (de) | 2007-10-10 |
| EP1841778B1 (de) | 2012-03-14 |
| JP2008527022A (ja) | 2008-07-24 |
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