ATE550330T1 - Verfahren zur trennung aminokonjugierter lipide - Google Patents

Verfahren zur trennung aminokonjugierter lipide

Info

Publication number
ATE550330T1
ATE550330T1 AT08751346T AT08751346T ATE550330T1 AT E550330 T1 ATE550330 T1 AT E550330T1 AT 08751346 T AT08751346 T AT 08751346T AT 08751346 T AT08751346 T AT 08751346T AT E550330 T1 ATE550330 T1 AT E550330T1
Authority
AT
Austria
Prior art keywords
lipids
aminoconjugated
separating
cyclic
isolatable
Prior art date
Application number
AT08751346T
Other languages
English (en)
Inventor
Aaron Garzon
Jean Hildesheim
Original Assignee
Biolab Ltd
Nasvax Ltd
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolab Ltd, Nasvax Ltd, Yissum Res Dev Co filed Critical Biolab Ltd
Application granted granted Critical
Publication of ATE550330T1 publication Critical patent/ATE550330T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/08Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT08751346T 2007-05-09 2008-05-11 Verfahren zur trennung aminokonjugierter lipide ATE550330T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91689107P 2007-05-09 2007-05-09
PCT/IL2008/000651 WO2008139467A2 (en) 2007-05-09 2008-05-11 Lipid conjugated cyclic carbonate derivatives, their synthesis, and uses

Publications (1)

Publication Number Publication Date
ATE550330T1 true ATE550330T1 (de) 2012-04-15

Family

ID=39682588

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08751346T ATE550330T1 (de) 2007-05-09 2008-05-11 Verfahren zur trennung aminokonjugierter lipide

Country Status (6)

Country Link
US (1) US8541605B2 (de)
EP (1) EP2176245B1 (de)
JP (1) JP2010530358A (de)
AT (1) ATE550330T1 (de)
AU (1) AU2008249578A1 (de)
WO (1) WO2008139467A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3250622B1 (de) * 2015-01-30 2018-11-07 Basf Se Nebenproduktarme polyphenylenpolymethylenpolyisocyanate
CN114957045B (zh) * 2022-07-05 2023-03-21 中国科学院过程工程研究所 一种制备戊二氨基甲酸酯的方法
WO2024083171A1 (zh) * 2022-10-20 2024-04-25 苏州艾博生物科技有限公司 脂质化合物和脂质纳米颗粒组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2873282A (en) 1952-04-05 1959-02-10 Jefferson Chem Co Inc Catalytic process for producing alkylene carbonates
US2773070A (en) 1952-10-31 1956-12-04 Jefferson Chem Co Inc Catalytic process for producing alkylene carbonates
WO1992016236A1 (en) 1991-03-19 1992-10-01 Rajadhyaksha Vithal J Compositions and method comprising aminoalcohol derivatives as membrane penetration enhancers
US6838530B2 (en) 2001-11-29 2005-01-04 Basf Corporation Method of preparing various multifunctional materials using limited starting reactants
AU2004246904B2 (en) 2003-06-18 2010-02-04 Biolab Ltd. Sphingolipids polyalkylamine conjugates for use in transfection

Also Published As

Publication number Publication date
WO2008139467A3 (en) 2009-03-19
US8541605B2 (en) 2013-09-24
JP2010530358A (ja) 2010-09-09
WO2008139467A2 (en) 2008-11-20
AU2008249578A1 (en) 2008-11-20
US20100305333A1 (en) 2010-12-02
EP2176245A2 (de) 2010-04-21
EP2176245B1 (de) 2012-03-21

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