ATE550438T1 - Verfahren zur quantitativen bestimmung der methylierungsdichte in einem dna-locus - Google Patents

Verfahren zur quantitativen bestimmung der methylierungsdichte in einem dna-locus

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Publication number
ATE550438T1
ATE550438T1 AT04796212T AT04796212T ATE550438T1 AT E550438 T1 ATE550438 T1 AT E550438T1 AT 04796212 T AT04796212 T AT 04796212T AT 04796212 T AT04796212 T AT 04796212T AT E550438 T1 ATE550438 T1 AT E550438T1
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Austria
Prior art keywords
methylation density
quantitatively determining
dna locus
locus
dna
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Application number
AT04796212T
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English (en)
Inventor
Jeffrey Jeddeloh
Nathan Lakey
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Orion Genomics Llc
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Publication of ATE550438T1 publication Critical patent/ATE550438T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT04796212T 2003-10-21 2004-10-21 Verfahren zur quantitativen bestimmung der methylierungsdichte in einem dna-locus ATE550438T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51342603P 2003-10-21 2003-10-21
US56172104P 2004-04-12 2004-04-12
US56156304P 2004-04-12 2004-04-12
PCT/US2004/035177 WO2005040399A2 (en) 2003-10-21 2004-10-21 Methods for quantitative determination of methylation density in a dna locus

Publications (1)

Publication Number Publication Date
ATE550438T1 true ATE550438T1 (de) 2012-04-15

Family

ID=34527938

Family Applications (2)

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AT04796072T ATE553218T1 (de) 2003-10-21 2004-10-21 Differentielle enzymatische fragmetierung
AT04796212T ATE550438T1 (de) 2003-10-21 2004-10-21 Verfahren zur quantitativen bestimmung der methylierungsdichte in einem dna-locus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT04796072T ATE553218T1 (de) 2003-10-21 2004-10-21 Differentielle enzymatische fragmetierung

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US (4) US7901880B2 (de)
EP (4) EP1689887B1 (de)
JP (2) JP4917891B2 (de)
AT (2) ATE553218T1 (de)
AU (2) AU2004286235B2 (de)
CA (2) CA2542542C (de)
ES (2) ES2383970T3 (de)
WO (2) WO2005042704A2 (de)

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CA2542526A1 (en) 2005-05-06
WO2005040399A2 (en) 2005-05-06
WO2005040399A3 (en) 2005-07-21
CA2542542A1 (en) 2005-05-12
JP2007512806A (ja) 2007-05-24
EP1689887A4 (de) 2007-12-19
CA2542526C (en) 2014-05-13
WO2005042704A3 (en) 2005-06-30
AU2004286235A1 (en) 2005-05-12
WO2005042704A2 (en) 2005-05-12
ES2382780T3 (es) 2012-06-13
US8163485B2 (en) 2012-04-24
JP2007522795A (ja) 2007-08-16
AU2004284456A1 (en) 2005-05-06
US7901880B2 (en) 2011-03-08
US20120100535A1 (en) 2012-04-26
JP4917891B2 (ja) 2012-04-18
JP4887154B2 (ja) 2012-02-29
EP2339024B1 (de) 2014-12-31
US20100240064A1 (en) 2010-09-23
EP2292795A2 (de) 2011-03-09
ES2383970T3 (es) 2012-06-27
AU2004286235B2 (en) 2011-05-12
EP1682677A4 (de) 2007-12-19
US7910296B2 (en) 2011-03-22
US8361719B2 (en) 2013-01-29
EP1689887A2 (de) 2006-08-16
ATE553218T1 (de) 2012-04-15
US20050153316A1 (en) 2005-07-14
AU2004284456B2 (en) 2012-04-19
EP1682677A2 (de) 2006-07-26
EP1689887B1 (de) 2012-03-21
EP2339024A1 (de) 2011-06-29
US20050158739A1 (en) 2005-07-21
EP2292795B1 (de) 2015-01-07
CA2542542C (en) 2015-09-15
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