ATE551073T1 - Markierte hgf-bindende peptide für bildgebung - Google Patents

Markierte hgf-bindende peptide für bildgebung

Info

Publication number
ATE551073T1
ATE551073T1 AT08750628T AT08750628T ATE551073T1 AT E551073 T1 ATE551073 T1 AT E551073T1 AT 08750628 T AT08750628 T AT 08750628T AT 08750628 T AT08750628 T AT 08750628T AT E551073 T1 ATE551073 T1 AT E551073T1
Authority
AT
Austria
Prior art keywords
imaging
binding peptides
labelled
monitoring
vivo
Prior art date
Application number
AT08750628T
Other languages
English (en)
Inventor
Edvin Johannesen
Alan Cuthbertson
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0709441A external-priority patent/GB0709441D0/en
Priority claimed from GB0715682A external-priority patent/GB0715682D0/en
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE551073T1 publication Critical patent/ATE551073T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4842—Monitoring progression or stage of a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Solid State Image Pick-Up Elements (AREA)
AT08750628T 2007-05-16 2008-05-16 Markierte hgf-bindende peptide für bildgebung ATE551073T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0709441A GB0709441D0 (en) 2007-05-16 2007-05-16 Peptide imaging agents
GB0715682A GB0715682D0 (en) 2007-08-13 2007-08-13 Peptide imaging agents
PCT/GB2008/001696 WO2008139207A2 (en) 2007-05-16 2008-05-16 Labelled hgf binding peptides for imaging

Publications (1)

Publication Number Publication Date
ATE551073T1 true ATE551073T1 (de) 2012-04-15

Family

ID=39743846

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08750628T ATE551073T1 (de) 2007-05-16 2008-05-16 Markierte hgf-bindende peptide für bildgebung

Country Status (17)

Country Link
US (1) US8529874B2 (de)
EP (1) EP2146749B1 (de)
JP (1) JP2010526859A (de)
KR (2) KR20150017387A (de)
CN (1) CN101848734B (de)
AT (1) ATE551073T1 (de)
AU (1) AU2008249821B2 (de)
BR (1) BRPI0811210B1 (de)
CA (1) CA2685553C (de)
ES (1) ES2385066T3 (de)
IL (1) IL201778A0 (de)
MX (1) MX2009012386A (de)
NZ (1) NZ581160A (de)
PL (1) PL2146749T3 (de)
RU (2) RU2475266C2 (de)
WO (1) WO2008139207A2 (de)
ZA (1) ZA200908016B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100017102A (ko) * 2007-05-16 2010-02-16 지이 헬스케어 에이에스 광학 조영제
GB0718967D0 (en) 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
GB0918321D0 (en) 2009-10-20 2009-12-02 Ge Healthcare As Cyclic peptide synthesis
GB201010878D0 (en) 2010-06-29 2010-08-11 Ge Healthcare As Dye compositiion and dye syntheses
JP2013534557A (ja) * 2010-06-29 2013-09-05 ジーイー・ヘルスケア・アクスイェ・セルスカプ 色素組成物及び色素合成法
GB201013808D0 (en) 2010-08-18 2010-09-29 Ge Healthcare Ltd Peptide radiotracer compositions
EP2625281A2 (de) * 2010-10-06 2013-08-14 EMD Millipore Corporation Cyaninverbindungen, konjugate daraus und verfahren zu ihrer verwendung
KR20140010096A (ko) 2011-03-01 2014-01-23 지이 헬쓰케어 리미티드 Ｐｅｔ 트레이서로서 방사능표지된 옥트레오테이트 유사체
GB201103696D0 (en) 2011-03-04 2011-04-20 Ge Healthcare Ltd Technetium labelled peptides
DE102011118029A1 (de) 2011-06-20 2012-12-20 Universität Leipzig Modifizierte antibiotische Peptide mit variabler systemischer Freisetzung
GB201116733D0 (en) 2011-09-28 2011-11-09 Ge Healthcare As Peptide margin imaging agents
GB201116862D0 (en) 2011-09-30 2011-11-09 Ge Healthcare As Infusion imaging method
GB201121914D0 (en) 2011-12-20 2012-02-01 Ge Healthcare Ltd Method for patient selection
US10046068B2 (en) * 2013-03-15 2018-08-14 Arizona Board Of Regents On Behalf Of Arizona State University Saccharide conjugates
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322456D0 (en) 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
CN105111773B (zh) * 2015-08-19 2017-06-27 大连理工大学 一类氨基菁类荧光染料及其制备方法和应用
GB201804835D0 (en) * 2018-03-26 2018-05-09 Ge Healthcare As Formulation and method of preparation
CN112129736B (zh) * 2020-09-22 2022-08-02 四川大学华西医院 粘蛋白和循环肿瘤细胞的均相可视化/荧光poct检测方法
WO2022258455A1 (en) * 2021-06-07 2022-12-15 Surgvision Gmbh Stable liquid phantom for near-infrared fluorescence verification
TW202404643A (zh) 2022-04-20 2024-02-01 大陸商同宜醫藥（蘇州）有限公司 化合物及用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4749718B2 (ja) * 2002-05-10 2011-08-17 カーネギー・メロン・ユニヴァーシティ 官能基を含有するキラルインドール中間体およびそれらの蛍光シアニン染料
GB0223249D0 (en) * 2002-10-08 2002-11-13 Amersham Plc Improved imaging agents
AU2004214420A1 (en) * 2003-02-19 2004-09-02 Sicel Technologies Inc. In vivo fluorescence sensors, systems, and related methods operating in conjunction with fluorescent analytes
EP2284180B1 (de) * 2003-03-03 2015-09-09 Dyax Corp. Verwendungen von Spezifisch an HGF-Rezeptor (cMET) bindenden Peptiden
NO20034350D0 (no) * 2003-09-29 2003-09-29 Amersham Health As Optisk avbilding av kolorektal kreft
WO2005044923A1 (en) * 2003-10-31 2005-05-19 Ge Healthcare Limited Cyanine dye labelling reagents
US7785566B2 (en) 2003-11-06 2010-08-31 Ge Healthcare, Inc. Pharmaceutical compounds
NO20035682D0 (no) 2003-12-18 2003-12-18 Amersham Health As Optisk avbildning av ösofagkreft og Barretts ösofag
US8236283B2 (en) * 2005-01-06 2012-08-07 Ge Healthcare As Optical imaging
WO2006078914A1 (en) * 2005-01-21 2006-07-27 Washington University In St. Louis Compounds having rd targeting motifs
GB0502277D0 (en) 2005-02-04 2005-03-09 Amersham Plc Novel imaging agents
DE602006020710D1 (de) 2005-04-22 2011-04-28 Fred Hutchinson Cancer Res Foundation Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs
NO20053354D0 (no) * 2005-07-11 2005-07-11 Amersham Health As Optical imaging contrast agent.

Also Published As

Publication number Publication date
EP2146749A2 (de) 2010-01-27
ZA200908016B (en) 2012-04-25
RU2009140478A (ru) 2011-06-27
RU2473361C9 (ru) 2013-06-20
CN101848734A (zh) 2010-09-29
RU2473361C2 (ru) 2013-01-27
US8529874B2 (en) 2013-09-10
US20100150843A1 (en) 2010-06-17
IL201778A0 (en) 2010-06-16
WO2008139207A2 (en) 2008-11-20
WO2008139207A3 (en) 2009-02-26
BRPI0811210B1 (pt) 2021-11-09
NZ581160A (en) 2012-05-25
CA2685553C (en) 2017-03-28
CA2685553A1 (en) 2008-11-20
KR20150017387A (ko) 2015-02-16
AU2008249821B2 (en) 2013-08-22
MX2009012386A (es) 2009-12-03
PL2146749T3 (pl) 2012-09-28
JP2010526859A (ja) 2010-08-05
RU2009140475A (ru) 2011-06-27
AU2008249821A1 (en) 2008-11-20
BRPI0811210A2 (pt) 2014-11-11
KR20100016543A (ko) 2010-02-12
EP2146749B1 (de) 2012-03-28
CN101848734B (zh) 2013-08-28
KR101578225B1 (ko) 2015-12-17
RU2475266C2 (ru) 2013-02-20
ES2385066T3 (es) 2012-07-17

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