ATE553185T1 - Expressionskassette und vektor zur transienten oder stabilen expression exogener moleküle - Google Patents

Expressionskassette und vektor zur transienten oder stabilen expression exogener moleküle

Info

Publication number
ATE553185T1
ATE553185T1 AT04711259T AT04711259T ATE553185T1 AT E553185 T1 ATE553185 T1 AT E553185T1 AT 04711259 T AT04711259 T AT 04711259T AT 04711259 T AT04711259 T AT 04711259T AT E553185 T1 ATE553185 T1 AT E553185T1
Authority
AT
Austria
Prior art keywords
expression
vector
exogeneous
transient
molecules
Prior art date
Application number
AT04711259T
Other languages
English (en)
Inventor
William Sisk
Holly Prentice
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Application granted granted Critical
Publication of ATE553185T1 publication Critical patent/ATE553185T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Paints Or Removers (AREA)
  • Tents Or Canopies (AREA)
AT04711259T 2003-02-14 2004-02-13 Expressionskassette und vektor zur transienten oder stabilen expression exogener moleküle ATE553185T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44817903P 2003-02-14 2003-02-14
PCT/US2004/004407 WO2004074439A2 (en) 2003-02-14 2004-02-13 An expression cassette and vector for transient or stable expression of exogenous molecules

Publications (1)

Publication Number Publication Date
ATE553185T1 true ATE553185T1 (de) 2012-04-15

Family

ID=32908549

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04711259T ATE553185T1 (de) 2003-02-14 2004-02-13 Expressionskassette und vektor zur transienten oder stabilen expression exogener moleküle

Country Status (21)

Country Link
US (2) US7494805B2 (de)
EP (1) EP1594955B1 (de)
JP (2) JP2006517802A (de)
KR (1) KR20050101554A (de)
CN (1) CN1774500B (de)
AT (1) ATE553185T1 (de)
AU (1) AU2004213797B2 (de)
BR (1) BRPI0407487A (de)
CA (1) CA2515481A1 (de)
DK (1) DK1594955T3 (de)
EA (2) EA200700469A1 (de)
ES (1) ES2384973T3 (de)
IL (1) IL170178A (de)
IS (1) IS7974A (de)
MX (1) MXPA05008523A (de)
NO (1) NO20054202L (de)
NZ (1) NZ542316A (de)
PL (1) PL378110A1 (de)
RS (1) RS20050614A (de)
WO (1) WO2004074439A2 (de)
ZA (1) ZA200506413B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1594955B1 (de) * 2003-02-14 2012-04-11 Biogen Idec MA Inc. Expressionskassette und vektor zur transienten oder stabilen expression exogener moleküle
EP2100877B1 (de) 2003-09-19 2012-01-25 Janssen Pharmaceutica N.V. 4-((Phenoxyalkyl)thio)-phenoxyessigsäuren und Analoga
GEP20094618B (en) * 2003-10-14 2009-02-25 Biogen Idec Inc Flp-mediated recombination
AU2005222963B2 (en) * 2004-03-15 2009-10-29 Biogen Idec Ma Inc. Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing
MY147518A (en) 2004-09-15 2012-12-31 Janssen Pharmaceutica Nv 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
JO3006B1 (ar) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك
GB0606190D0 (en) 2006-03-28 2006-05-10 Isis Innovation Construct
UY30288A1 (es) 2006-04-18 2007-08-31 Janssen Pharmaceutica Nv Derivados del ácido benzoazepin-oxi-acético como agonistas de ppar-delta usados para aumentar hdl-c. reducir ldl-c y reducir colesterol
KR20090094812A (ko) * 2006-10-18 2009-09-08 더 스크립스 리서치 인스티튜트 포유동물 세포에서 비천연 아미노산의 단백질 내로의 유전적 도입
WO2011017319A1 (en) 2009-08-03 2011-02-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods of treating disorders associated with protein polymerization
US8809617B2 (en) * 2009-11-05 2014-08-19 The University of Pittsburgh—Of the Commonwealth System of Higher Education Automated high-content live animal drug screening using C. elegans
US9072772B2 (en) 2009-11-05 2015-07-07 University of Pittsburgh—of the Commonwealth System of Higher Education Methods of treating disorders associated with protein aggregation
AU2010339858B2 (en) * 2009-12-21 2016-01-28 Sanofi Transgenic non-human animal and uses thereof
UY33126A (es) * 2009-12-21 2011-07-29 Sanofi Sa Animal transgénico no humano y sus usos
US8993316B2 (en) 2011-11-16 2015-03-31 Brian P. Hanley Methods and compositions for gene therapy and GHRH therapy
WO2013158664A2 (en) 2012-04-17 2013-10-24 Kythera Biopharmaceuticals, Inc. Use of engineered viruses to specifically kill senescent cells
EP2895610B1 (de) 2012-09-13 2019-11-06 Indiana University Research and Technology Corporation Zusammensetzungen und systeme zur induzierung von krankheitsresistenz bei pflanzen und verfahren zu ihrer verwendung
PT2928923T (pt) 2012-12-10 2020-03-27 Biogen Ma Inc Anticorpos antígenos 2 de células dendríticas anti-sangue e os seus usos
AU2014246731A1 (en) * 2013-03-30 2015-11-19 Usha Biotech Limited Methods and constructs for expressing biologically active proteins in mammalian cells
WO2015162930A1 (ja) * 2014-04-24 2015-10-29 一般社団法人 医療産業イノベーション機構 タンパク質発現を向上させる方法およびタンパク質発現用組成物
TWI747098B (zh) 2018-12-21 2021-11-21 美商美國禮來大藥廠 抗angptl3/8複合物抗體及其使用方法
US11415263B2 (en) * 2020-03-20 2022-08-16 Edwards Vacuum Llc Conversion kit for a support frame, a support frame and an integrated vacuum system mounted in a support frame

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
KR100283541B1 (ko) 1991-10-25 2001-03-02 크리스토퍼 엘. 와이트, 스코트 지. 홀퀴스트, 스티븐 엘. 말라스카 신규 사이토킨
ATE229076T1 (de) 1992-04-02 2002-12-15 Sembiosys Genetics Inc Cis elemente des ölkörperproteins als regulationische signale
JPH10510433A (ja) 1995-06-06 1998-10-13 アイシス・ファーマシューティカルス・インコーポレーテッド 高いキラル純度のホスホロチオエート結合を有するオリゴヌクレオチド
MX9709447A (es) 1995-06-07 1998-02-28 Immunex Corp Nueva muteina cd4ol.
US5985662A (en) 1995-07-13 1999-11-16 Isis Pharmaceuticals Inc. Antisense inhibition of hepatitis B virus replication
US6087129A (en) * 1996-01-19 2000-07-11 Betagene, Inc. Recombinant expression of proteins from secretory cell lines
WO1997040165A1 (en) * 1996-04-23 1997-10-30 The Wistar Institute Of Anatomy And Biology Novel human cytomegalovirus dna constructs and uses therefor
EP0988388A2 (de) * 1997-07-24 2000-03-29 Valentis Inc. Ghrh-expressionssystem und dessen verwendungsmethoden
AU2324999A (en) * 1998-01-16 1999-08-02 California Pacific Medical Center Research Institute Methods and compositions for gene delivery
US6455677B1 (en) 1998-04-30 2002-09-24 Boehringer Ingelheim International Gmbh FAPα-specific antibody with improved producibility
EP0953639A1 (de) * 1998-04-30 1999-11-03 Boehringer Ingelheim International GmbH FAPalpha-spezifischer Antikörper mit verbesserter Produzierbarkeit
WO1999061066A2 (en) * 1998-05-27 1999-12-02 Avigen, Inc. Convection-enhanced delivery of aav vectors
EP1092768A1 (de) * 1999-10-16 2001-04-18 ARTEMIS Pharmaceuticals GmbH Konstrukt zum bedingten einfangen und Disruption von Genen
EP1292686A1 (de) 2000-06-07 2003-03-19 Smittskyddsinstitutet Genexpressionskassette und deren verwendung
WO2002002765A2 (en) 2000-07-05 2002-01-10 Transgene S.A. Chimeric promoters for controlling expression in smooth muscle cells
JP2002233374A (ja) * 2001-02-06 2002-08-20 Japan Science & Technology Corp 遺伝子導入及び／又は遺伝子欠損非ヒト動物作製用ベクター
DE10133407A1 (de) 2001-07-13 2003-01-23 Basf Ag Expressionskassetten zur transgenen Expression von Nukleinsäuren
US20030235823A1 (en) 2002-06-24 2003-12-25 The University Of Alabama Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation
EP1594955B1 (de) * 2003-02-14 2012-04-11 Biogen Idec MA Inc. Expressionskassette und vektor zur transienten oder stabilen expression exogener moleküle

Also Published As

Publication number Publication date
BRPI0407487A (pt) 2006-02-14
MXPA05008523A (es) 2005-10-20
IS7974A (is) 2005-08-11
ES2384973T3 (es) 2012-07-16
HK1084690A1 (en) 2006-08-04
WO2004074439A9 (en) 2004-12-23
AU2004213797B2 (en) 2009-09-17
EP1594955A4 (de) 2006-07-19
RS20050614A (sr) 2007-12-31
NZ542316A (en) 2006-04-28
IL170178A (en) 2011-12-29
DK1594955T3 (da) 2012-06-25
WO2004074439A3 (en) 2004-10-28
CN1774500A (zh) 2006-05-17
NO20054202L (no) 2005-11-11
US7494805B2 (en) 2009-02-24
KR20050101554A (ko) 2005-10-24
NO20054202D0 (no) 2005-09-09
EP1594955A2 (de) 2005-11-16
JP2006517802A (ja) 2006-08-03
WO2004074439A2 (en) 2004-09-02
EA200501296A1 (ru) 2006-04-28
JP2010213718A (ja) 2010-09-30
AU2004213797A1 (en) 2004-09-02
US20100158879A1 (en) 2010-06-24
EA200700469A1 (ru) 2008-10-30
CA2515481A1 (en) 2004-09-02
US20060141625A1 (en) 2006-06-29
EP1594955B1 (de) 2012-04-11
EA008439B1 (ru) 2007-06-29
PL378110A1 (pl) 2006-03-06
CN1774500B (zh) 2011-03-02
ZA200506413B (en) 2006-04-26

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