ATE505535T1 - Verfahren zur herstellung stabiler b-lymphozyten - Google Patents

Verfahren zur herstellung stabiler b-lymphozyten

Info

Publication number
ATE505535T1
ATE505535T1 AT06842246T AT06842246T ATE505535T1 AT E505535 T1 ATE505535 T1 AT E505535T1 AT 06842246 T AT06842246 T AT 06842246T AT 06842246 T AT06842246 T AT 06842246T AT E505535 T1 ATE505535 T1 AT E505535T1
Authority
AT
Austria
Prior art keywords
lymphocytes
producing stable
producing
stable
methods
Prior art date
Application number
AT06842246T
Other languages
English (en)
Inventor
Herman Groen
Hans Westra
Original Assignee
Iq Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iq Corp filed Critical Iq Corp
Application granted granted Critical
Publication of ATE505535T1 publication Critical patent/ATE505535T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT06842246T 2005-08-23 2006-08-23 Verfahren zur herstellung stabiler b-lymphozyten ATE505535T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71062605P 2005-08-23 2005-08-23
PCT/IB2006/003670 WO2007063415A2 (en) 2005-08-23 2006-08-23 Methods of producing stable b-lymphocytes

Publications (1)

Publication Number Publication Date
ATE505535T1 true ATE505535T1 (de) 2011-04-15

Family

ID=37968195

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06842246T ATE505535T1 (de) 2005-08-23 2006-08-23 Verfahren zur herstellung stabiler b-lymphozyten

Country Status (6)

Country Link
US (2) US20070065919A1 (de)
EP (1) EP1928999B1 (de)
AT (1) ATE505535T1 (de)
CA (1) CA2619784A1 (de)
DE (1) DE602006021324D1 (de)
WO (2) WO2007049152A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0619908A2 (pt) * 2005-12-16 2011-10-25 Ribovax Biotechnologies Sa método para imortalização de uma população de células, população de células, população de células oligoclonal ou monoclonal, cultura celular, sobrenadante de uma cultura celular, biclioteca de dnas, uso de uma população de células, cultura celular, sobrenadante ou biblioteca de dnas, kit para identificar e produzir um anticorpo monoclonal, método para produzir uma cultura celular, e método para produzir um anticorpo monoclonal
AU2008284015B2 (en) 2007-08-03 2014-05-15 Musc Foundation For Research Development Human monoclonal antibodies and methods for producing the same
EP2242836B1 (de) * 2008-01-28 2015-05-20 Thomas Jefferson University Verfahren zur herstellung von hybridzellen zur expression nützlicher antikörper
US8703486B2 (en) 2008-09-23 2014-04-22 UNIVERSITé LAVAL Method for polyclonal immunoglobulin G production by human B cells
US20110129460A1 (en) * 2009-01-14 2011-06-02 IQ Therapeutics B.V. Combination Antibodies For The Treatment And Prevention Of Disease Caused By Bacillus Anthracis And Related Bacteria And Their Toxins
US9260517B2 (en) 2009-11-17 2016-02-16 Musc Foundation For Research Development Human monoclonal antibodies to human nucleolin
CN108884442B (zh) 2016-03-30 2023-06-02 豪夫迈·罗氏有限公司 B细胞培养方法
AU2017298298B2 (en) 2016-07-18 2024-03-07 President And Fellows Of Harvard College Human lymphoid tissue-on-chip
EP3562936B1 (de) 2017-01-02 2024-05-22 F. Hoffmann-La Roche AG Verfahren zur kultivierung von b-zellen
CN110621773B (zh) 2017-05-19 2023-06-09 豪夫迈·罗氏有限公司 用于产生胸腺细胞上清液的方法
WO2019105864A1 (en) 2017-11-30 2019-06-06 F. Hoffmann-La Roche Ag B-cell cultivation method
WO2021027057A1 (zh) * 2019-08-15 2021-02-18 成都冕康生物科技有限公司 一种针对ebv病毒抗原的b细胞疫苗及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126259A (en) 1987-12-24 1992-06-30 Takeda Chemical Industries, Ltd. Human b. lymphoblastoid cell, hybridoma, antibody and production of antibody
JPH02131574A (ja) * 1988-06-17 1990-05-21 Biogenex Lab ミニクローン
WO1990000404A1 (en) * 1988-07-15 1990-01-25 United Biotech, Inc. Enrichment of antigen-specific polyclonal antibodies through selection of immortal hybrid cells
DK0488470T3 (da) 1990-11-26 1997-12-22 Akzo Nobel Nv Fremgangsmåde til fremstilling af antistoffer
DE4134297A1 (de) * 1991-10-17 1993-04-22 Behringwerke Ag Monoclonale antikoerper gegen mycoplasma pneumoniae, diese produzierende hybridome, verfahren zu deren herstellung sowie deren verwendung
CA2132421C (en) * 1992-03-19 2010-11-23 Gerald W. Fischer Broadly reactive opsonic antibodies that react with common staphylococcal antigens
ATE309267T1 (de) * 1994-04-28 2005-11-15 Boehringer Ingelheim Pharma Methode zur proliferation und differenzierung von b-zellen und verwendungen dafür
FI98493C (fi) * 1994-06-10 1997-07-10 Olavi Kajander Kasvutekijävalmiste, menetelmä sen valmistamiseksi ja käyttämiseksi ja sitä sisältävä elatusaine
US7115264B2 (en) * 2001-11-05 2006-10-03 Inhibitex Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections
US7169903B2 (en) * 2001-12-21 2007-01-30 Biosynexus Incorporated Multifunctional monoclonal antibodies directed to peptidoglycan of gram-positive bacteria
JP2008541758A (ja) * 2005-06-02 2008-11-27 アストラゼネカ エービー Ｃｄ２０に対する抗体およびその使用

Also Published As

Publication number Publication date
CA2619784A1 (en) 2007-06-07
WO2007063415A3 (en) 2007-11-01
US20070065919A1 (en) 2007-03-22
EP1928999A2 (de) 2008-06-11
US20070098711A1 (en) 2007-05-03
WO2007049152A3 (en) 2007-10-04
WO2007063415A2 (en) 2007-06-07
EP1928999B1 (de) 2011-04-13
US7807415B2 (en) 2010-10-05
WO2007049152A2 (en) 2007-05-03
DE602006021324D1 (de) 2011-05-26

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