ATE554397T1 - Verfahren zur stabilisierung von alpha-thrombin in einer thrombinhaltigen lösung - Google Patents

Verfahren zur stabilisierung von alpha-thrombin in einer thrombinhaltigen lösung

Info

Publication number
ATE554397T1
ATE554397T1 AT07849800T AT07849800T ATE554397T1 AT E554397 T1 ATE554397 T1 AT E554397T1 AT 07849800 T AT07849800 T AT 07849800T AT 07849800 T AT07849800 T AT 07849800T AT E554397 T1 ATE554397 T1 AT E554397T1
Authority
AT
Austria
Prior art keywords
thrombin
solution containing
solution
stabilizing
stabilizing alpha
Prior art date
Application number
AT07849800T
Other languages
English (en)
Inventor
Remi Ikeda
Chizuru Morikawa
Hirokazu Yago
Original Assignee
Sekisui Medical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sekisui Medical Co Ltd filed Critical Sekisui Medical Co Ltd
Application granted granted Critical
Publication of ATE554397T1 publication Critical patent/ATE554397T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07849800T 2006-12-21 2007-12-06 Verfahren zur stabilisierung von alpha-thrombin in einer thrombinhaltigen lösung ATE554397T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006344121 2006-12-21
PCT/JP2007/001367 WO2008075455A1 (ja) 2006-12-21 2007-12-06 トロンビン含有溶液中のα－トロンビンの安定化方法

Publications (1)

Publication Number Publication Date
ATE554397T1 true ATE554397T1 (de) 2012-05-15

Family

ID=39536094

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07849800T ATE554397T1 (de) 2006-12-21 2007-12-06 Verfahren zur stabilisierung von alpha-thrombin in einer thrombinhaltigen lösung

Country Status (7)

Country Link
US (1) US8580532B2 (de)
EP (1) EP2096440B1 (de)
JP (1) JP5121725B2 (de)
CN (1) CN101558310B (de)
AT (1) ATE554397T1 (de)
ES (1) ES2382758T3 (de)
WO (1) WO2008075455A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10046081B2 (en) 2008-04-11 2018-08-14 The Henry M Jackson Foundation For The Advancement Of Military Medicine, Inc. Electrospun dextran fibers and devices formed therefrom
EP3242656A4 (de) * 2015-01-06 2018-08-29 St. Teresa Medical, Inc. Hämostatika
JP6962819B2 (ja) * 2015-04-10 2021-11-05 アディマブ， エルエルシー 親ホモ二量体抗体種からのヘテロ二量体多重特異性抗体の精製方法
CA3004734A1 (en) 2015-11-12 2017-06-18 St. Teresa Medical, Inc. A method of sealing a durotomy
CN106350500B (zh) * 2016-09-30 2018-02-23 迈克生物股份有限公司 凝血酶溶液
CN106350499B (zh) * 2016-09-30 2018-07-10 迈克生物股份有限公司 凝血酶溶液的稳定剂
CN106350501B (zh) * 2016-09-30 2018-06-01 迈克生物股份有限公司 凝血酶溶液的稳定剂
CN106337044B (zh) * 2016-09-30 2018-08-31 迈克生物股份有限公司 凝血酶溶液
CN106480007B (zh) * 2016-09-30 2018-02-23 迈克生物股份有限公司 凝血酶溶液的稳定剂
JP6889535B2 (ja) * 2016-10-05 2021-06-18 デンカ株式会社 赤血球の凝集方法及び分離方法並びに赤血球凝集用試薬
CN107942063A (zh) * 2016-10-13 2018-04-20 北京众驰伟业科技发展有限公司 一种血浆纤维蛋白原的检测试剂、其检测方法及应用
CN106645751B (zh) * 2016-12-27 2018-08-03 北京赛科希德科技股份有限公司 一种纤维蛋白原含量检测试剂盒
US10953128B2 (en) 2017-11-02 2021-03-23 St. Teresa Medical, Inc. Fibrin sealant products
CN112578130A (zh) * 2019-09-30 2021-03-30 积水医疗科技(苏州)有限公司 凝血酶溶液、试剂盒、凝血酶的稳定化方法、检测试剂以及凝血酶时间的测定方法
CN118010469B (zh) * 2024-04-08 2024-07-02 中国人民解放军军事科学院军事医学研究院 一种纤维蛋白原浓度定量检测稀释液及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696812A (en) * 1985-10-28 1987-09-29 Warner-Lambert Company Thrombin preparations
JPS6440433A (en) 1987-08-05 1989-02-10 Green Cross Corp Aqueous liquid composition of thrombin
AU7320300A (en) * 1999-09-27 2001-04-30 International Reagents Corporation Means of stabilizing thrombin and compositions
DE10012732A1 (de) * 2000-03-18 2001-09-20 Aventis Behring Gmbh Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung
JP2004191367A (ja) 2002-11-28 2004-07-08 Sysmex Corp トロンビン試薬及び検査試薬キット
JP5253501B2 (ja) * 2007-06-15 2013-07-31 ザイモジェネティクス， インコーポレイテッド 安定化トロンビン組成物
US20090101809A1 (en) * 2007-09-05 2009-04-23 Zymogenetics, Inc. Mass spectrometry-based quantitative assay for determining abundance of molecular species in a composition

Also Published As

Publication number Publication date
WO2008075455A1 (ja) 2008-06-26
JP5121725B2 (ja) 2013-01-16
EP2096440A1 (de) 2009-09-02
EP2096440B1 (de) 2012-04-18
CN101558310A (zh) 2009-10-14
CN101558310B (zh) 2013-05-08
EP2096440A4 (de) 2010-03-24
ES2382758T3 (es) 2012-06-13
US20100047834A1 (en) 2010-02-25
US8580532B2 (en) 2013-11-12
JPWO2008075455A1 (ja) 2010-04-08

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