ATE554751T1 - Nanopartikel mit einem nicht ionisierbaren polymer und einem anionischen zellulosepolymer - Google Patents
Nanopartikel mit einem nicht ionisierbaren polymer und einem anionischen zellulosepolymerInfo
- Publication number
- ATE554751T1 ATE554751T1 AT08762998T AT08762998T ATE554751T1 AT E554751 T1 ATE554751 T1 AT E554751T1 AT 08762998 T AT08762998 T AT 08762998T AT 08762998 T AT08762998 T AT 08762998T AT E554751 T1 ATE554751 T1 AT E554751T1
- Authority
- AT
- Austria
- Prior art keywords
- polymer
- nanoparticles
- ionizable
- anionic cellulose
- cellulose polymer
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 4
- 239000002105 nanoparticle Substances 0.000 title abstract 2
- 229920006321 anionic cellulose Polymers 0.000 title 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94952207P | 2007-07-13 | 2007-07-13 | |
| PCT/IB2008/001776 WO2009010837A2 (en) | 2007-07-13 | 2008-06-30 | Nanoparticles comprising a non-ionizable polymer and an anionic cellulosic polymer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554751T1 true ATE554751T1 (de) | 2012-05-15 |
Family
ID=39731304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08762998T ATE554751T1 (de) | 2007-07-13 | 2008-06-30 | Nanopartikel mit einem nicht ionisierbaren polymer und einem anionischen zellulosepolymer |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100266692A1 (de) |
| EP (1) | EP2178519B1 (de) |
| AT (1) | ATE554751T1 (de) |
| WO (1) | WO2009010837A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU227970B1 (en) * | 2007-07-10 | 2012-07-30 | Egis Gyogyszergyar Nyrt | Pharmaceutical compositions containing silicones of high volatility |
| EP2231169B1 (de) * | 2007-12-06 | 2016-05-04 | Bend Research, Inc. | Pharmazeutische zusammensetzungen mit nanopartikeln und resuspensionsmaterial |
| EP2240162A4 (de) | 2007-12-06 | 2013-10-09 | Bend Res Inc | Nanoteilchen mit einem nicht-ionisierbaren polymer und einem amin-funktionalisierten methacrylat-copolymer |
| ES2430940T3 (es) | 2008-02-28 | 2013-11-22 | University Of Virginia Patent Foundation | Gen del transportador de serotonina y tratamiento del alcoholismo |
| JP5470032B2 (ja) | 2009-08-12 | 2014-04-16 | 富士フイルム株式会社 | セルロース誘導体、熱成形材料、成形体及びその製造方法並びに電気電子機器用筐体 |
| US9023886B2 (en) | 2009-11-10 | 2015-05-05 | Celgene Corporation | Nanosuspension of a poorly soluble drug via microfluidization process |
| HUE035574T2 (en) | 2010-07-02 | 2018-05-28 | Univ Virginia Patent Foundation | Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence |
| US20130096173A1 (en) | 2011-09-09 | 2013-04-18 | Bankole A. Johnson | Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence |
| US10045935B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
| US10045965B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
| US11154535B2 (en) | 2012-07-31 | 2021-10-26 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
| WO2017062920A1 (en) * | 2015-10-07 | 2017-04-13 | Chopra Sunandini | Nanoparticles with ph triggered drug release |
| CA3168667A1 (en) | 2020-01-24 | 2021-07-29 | Nanocopoeia, Llc | Amorphous solid dispersions of dasatinib and uses thereof |
| EP4096791A1 (de) | 2020-01-31 | 2022-12-07 | Nanocopoeia LLC | Amorphe nilotinib-mikropartikel und deren verwendungen |
| IL297776A (en) | 2020-04-30 | 2022-12-01 | Nanocopoeia Llc | Orally disintegrating tablets containing an amorphous solid dispersion of nalotinib |
| US11980619B2 (en) | 2021-07-28 | 2024-05-14 | Nanocopoeia, Llc | Pharmaceutical compositions and crushable tablets including amorphous solid dispersions of dasatinib and uses |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2608988B1 (fr) | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| US20040018236A1 (en) | 1995-05-08 | 2004-01-29 | Robert Gurny | Nanoparticles for oral administration of pharmaceutical agents of low solubility |
| WO1999033558A1 (en) * | 1997-12-29 | 1999-07-08 | Universite De Geneve | Method for producing an aqueous colloidal dispersion of nanoparticles |
| US6410523B1 (en) * | 1998-04-10 | 2002-06-25 | Chugai Seiyaku Kabushiki Kaisha | Vitamin D derivatives substituted at the 2beta-position |
| ATE293977T1 (de) * | 1999-12-08 | 2005-05-15 | Pharmacia Corp | Nanopartikelzusammensetzungen enthaltend eplerenon |
| DZ3227A1 (fr) * | 1999-12-23 | 2001-07-05 | Pfizer Prod Inc | Compositions pharmaceutiques fournissant des concentrations de medicaments ameliorees |
-
2008
- 2008-06-30 WO PCT/IB2008/001776 patent/WO2009010837A2/en not_active Ceased
- 2008-06-30 US US12/451,812 patent/US20100266692A1/en not_active Abandoned
- 2008-06-30 AT AT08762998T patent/ATE554751T1/de active
- 2008-06-30 EP EP08762998A patent/EP2178519B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009010837A3 (en) | 2009-03-12 |
| US20100266692A1 (en) | 2010-10-21 |
| WO2009010837A2 (en) | 2009-01-22 |
| EP2178519B1 (de) | 2012-04-25 |
| EP2178519A2 (de) | 2010-04-28 |
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