ATE555119T1 - Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen - Google Patents

Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen

Info

Publication number
ATE555119T1
ATE555119T1 AT04796291T AT04796291T ATE555119T1 AT E555119 T1 ATE555119 T1 AT E555119T1 AT 04796291 T AT04796291 T AT 04796291T AT 04796291 T AT04796291 T AT 04796291T AT E555119 T1 ATE555119 T1 AT E555119T1
Authority
AT
Austria
Prior art keywords
variants
expression
protease inhibitors
filamentous fungi
filamentous
Prior art date
Application number
AT04796291T
Other languages
English (en)
Inventor
Nobel Hans De
David A Estell
Wei Liu
Scott D Power
Brian Schmidt
Huaming Wang
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Application granted granted Critical
Publication of ATE555119T1 publication Critical patent/ATE555119T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT04796291T 2003-11-06 2004-10-22 Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen ATE555119T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51815403P 2003-11-06 2003-11-06
PCT/US2004/035278 WO2005047302A1 (en) 2003-11-06 2004-10-22 Expression in filamentous fungi of protease inhibitors and variants thereof

Publications (1)

Publication Number Publication Date
ATE555119T1 true ATE555119T1 (de) 2012-05-15

Family

ID=34590229

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04796291T ATE555119T1 (de) 2003-11-06 2004-10-22 Expression von proteaseinhibitoren und varianten davon in filamentösen pilzen

Country Status (9)

Country Link
US (3) US7279564B2 (de)
EP (2) EP2292641B1 (de)
JP (1) JP4834554B2 (de)
KR (3) KR20120099303A (de)
CN (2) CN101857867A (de)
AT (1) ATE555119T1 (de)
CA (1) CA2545053C (de)
DK (1) DK1689766T3 (de)
WO (1) WO2005047302A1 (de)

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WO2005047314A2 (en) * 2003-11-06 2005-05-26 Genencor International, Inc. Fgf-beta binding and supported peptides
CN101146907B (zh) * 2005-04-12 2015-04-08 金克克国际有限公司 蛋白质生产被改变的基因失活突变体
CN101278051B (zh) * 2005-05-05 2011-10-05 金克克国际有限公司 个人护理组合物及其使用方法
US8206949B2 (en) * 2005-11-15 2012-06-26 Glycofi, Inc. Production of glycoproteins with reduced O-glycosylation
US20080026376A1 (en) 2006-07-11 2008-01-31 Huaming Wang KEX2 cleavage regions of recombinant fusion proteins
US8198046B2 (en) * 2006-07-11 2012-06-12 Danisco Us Inc. KEX2 cleavage regions of recombinant fusion proteins
CA2672603A1 (en) 2006-12-18 2008-06-26 Danisco Us, Inc., Genencor Division Novel laccases, compositions and methods of use
CN101842479A (zh) * 2007-11-01 2010-09-22 丹尼斯科美国公司 用于改良宿主细胞内蛋白质生产的信号序列和共表达的分子伴侣
US7772181B2 (en) 2008-10-15 2010-08-10 Danisco Us Inc. Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors
AU2008362898B2 (en) * 2008-10-15 2013-02-28 Danisco Us Inc. Modified variant Bowman Birk Protease inhibitors
US7803902B2 (en) 2008-10-15 2010-09-28 Danisco Us Inc. Modified variant bowman birk protease inhibitors
GB0921001D0 (en) 2009-11-30 2010-01-13 Aqua Bio Technology Asa Products and uses
CN103988973A (zh) * 2009-12-30 2014-08-20 索莱有限责任公司 大豆乳清蛋白组合物及其回收方法
RU2608639C2 (ru) * 2010-08-25 2017-01-23 ДАНИСКО ЮЭс ИНК. Мицелиальные грибы, имеющие фенотип измененной вязкости
US9279007B2 (en) * 2010-11-22 2016-03-08 Amicus Therapeutics, Inc. Signal sequences to improve protein expressions and secretion of recombinant enzymes and other proteins
DK2699668T3 (en) * 2011-04-22 2018-02-26 Danisco Us Inc FILAMENTOUS FUNGI WITH A CHANGED VISCOSITY PHENYTOP
US9434934B2 (en) * 2013-07-29 2016-09-06 Academia Sinica Heat stable keratinase and use thereof
JP6544503B2 (ja) * 2014-01-30 2019-07-17 福岡県 コラゲナーゼ阻害剤、並びにコラゲナーゼ阻害剤を配合した化粧料組成物及び機能性食品
AR116624A1 (es) 2018-10-10 2021-05-26 Amicus Therapeutics Inc Composiciones de polipéptidos estabilizados por enlaces disulfuro y métodos de uso
PH12021553240A1 (en) * 2019-06-26 2023-02-20 Eg Crop Science Inc Identification of resistance genes from wild relatives of banana and their uses in controlling panama disease
CN112553274B (zh) * 2020-12-02 2023-06-13 江南大学 大豆提取物Bowman-Birk inhibitor切割DNA的方法

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US5411873A (en) 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
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Also Published As

Publication number Publication date
US20080234465A1 (en) 2008-09-25
KR20060111451A (ko) 2006-10-27
US7279564B2 (en) 2007-10-09
EP1689766A4 (de) 2008-07-23
CN1875029A (zh) 2006-12-06
DK1689766T3 (da) 2012-07-16
CA2545053C (en) 2016-04-19
HK1100181A1 (en) 2007-09-07
JP2007528212A (ja) 2007-10-11
KR20120099303A (ko) 2012-09-07
EP2292641B1 (de) 2017-12-06
KR101211444B1 (ko) 2012-12-13
KR20110119844A (ko) 2011-11-02
EP1689766A1 (de) 2006-08-16
US7592420B2 (en) 2009-09-22
US7592157B2 (en) 2009-09-22
CN101857867A (zh) 2010-10-13
EP1689766B1 (de) 2012-04-25
US20050153399A1 (en) 2005-07-14
EP2292641A2 (de) 2011-03-09
CA2545053A1 (en) 2005-05-26
US20080131932A1 (en) 2008-06-05
WO2005047302A1 (en) 2005-05-26
EP2292641A3 (de) 2011-06-22
JP4834554B2 (ja) 2011-12-14
KR101348530B1 (ko) 2014-02-14
CN1875029B (zh) 2010-06-16

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