ATE556047T1 - Kristalline feste form der (2s-5z)-2-amino-7- - Google Patents

Kristalline feste form der (2s-5z)-2-amino-7-

Info

Publication number
ATE556047T1
ATE556047T1 AT03793292T AT03793292T ATE556047T1 AT E556047 T1 ATE556047 T1 AT E556047T1 AT 03793292 T AT03793292 T AT 03793292T AT 03793292 T AT03793292 T AT 03793292T AT E556047 T1 ATE556047 T1 AT E556047T1
Authority
AT
Austria
Prior art keywords
amino
solid form
crystalline solid
crystalline
solid
Prior art date
Application number
AT03793292T
Other languages
English (en)
Inventor
Ann HALLINAN
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Application granted granted Critical
Publication of ATE556047T1 publication Critical patent/ATE556047T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Addiction (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
AT03793292T 2002-08-23 2003-08-22 Kristalline feste form der (2s-5z)-2-amino-7- ATE556047T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40552602P 2002-08-23 2002-08-23
PCT/US2003/026347 WO2004018412A1 (en) 2002-08-23 2003-08-22 Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid

Publications (1)

Publication Number Publication Date
ATE556047T1 true ATE556047T1 (de) 2012-05-15

Family

ID=31946886

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03793292T ATE556047T1 (de) 2002-08-23 2003-08-22 Kristalline feste form der (2s-5z)-2-amino-7-

Country Status (20)

Country Link
US (1) US6998503B2 (de)
EP (1) EP1534668B1 (de)
JP (1) JP4708024B2 (de)
KR (1) KR100893647B1 (de)
CN (1) CN100588647C (de)
AR (1) AR041038A1 (de)
AT (1) ATE556047T1 (de)
AU (1) AU2003258327B2 (de)
BR (1) BR0313752A (de)
CA (1) CA2494583C (de)
ES (1) ES2384969T3 (de)
IL (2) IL166599A0 (de)
MX (1) MXPA05001708A (de)
NO (1) NO20050609L (de)
NZ (1) NZ538184A (de)
PL (1) PL375557A1 (de)
RU (1) RU2314290C2 (de)
TW (1) TWI340133B (de)
WO (1) WO2004018412A1 (de)
ZA (1) ZA200501134B (de)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127376D0 (en) 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
EP0751930B1 (de) * 1994-03-24 2000-01-05 G.D. SEARLE & CO. Amidino-derivative als no-synthese-inhibitoren
US5684008A (en) * 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
US5945408A (en) * 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
MY131964A (en) * 2000-09-15 2007-09-28 Pharmacia Corp 2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors
GB0031179D0 (en) * 2000-12-21 2001-01-31 Glaxo Group Ltd Nitric oxide synthase inhibitors
US7012098B2 (en) * 2001-03-23 2006-03-14 Pharmacia Corporation Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers

Also Published As

Publication number Publication date
KR100893647B1 (ko) 2009-04-17
WO2004018412A1 (en) 2004-03-04
IL166599A0 (en) 2006-01-15
AR041038A1 (es) 2005-04-27
CA2494583A1 (en) 2004-03-04
NO20050609L (no) 2005-03-21
BR0313752A (pt) 2005-06-21
EP1534668A1 (de) 2005-06-01
RU2005104954A (ru) 2005-07-20
TW200413291A (en) 2004-08-01
HK1078562A1 (en) 2006-03-17
US6998503B2 (en) 2006-02-14
CA2494583C (en) 2010-02-02
ZA200501134B (en) 2006-10-25
ES2384969T3 (es) 2012-07-16
KR20050058443A (ko) 2005-06-16
TWI340133B (en) 2011-04-11
JP4708024B2 (ja) 2011-06-22
MXPA05001708A (es) 2005-04-19
IL166599A (en) 2010-12-30
NZ538184A (en) 2008-02-29
JP2005536541A (ja) 2005-12-02
AU2003258327B2 (en) 2009-05-21
US20040132822A1 (en) 2004-07-08
PL375557A1 (en) 2005-11-28
AU2003258327A1 (en) 2004-03-11
CN100588647C (zh) 2010-02-10
CN1678572A (zh) 2005-10-05
EP1534668B1 (de) 2012-05-02
RU2314290C2 (ru) 2008-01-10

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