ATE557101T1 - Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuum - Google Patents
Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuumInfo
- Publication number
- ATE557101T1 ATE557101T1 AT05723099T AT05723099T ATE557101T1 AT E557101 T1 ATE557101 T1 AT E557101T1 AT 05723099 T AT05723099 T AT 05723099T AT 05723099 T AT05723099 T AT 05723099T AT E557101 T1 ATE557101 T1 AT E557101T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- subject
- tolerant phenotype
- transplantation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000002054 transplantation Methods 0.000 title 1
- 238000011156 evaluation Methods 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000002650 immunosuppressive therapy Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53843904P | 2004-01-21 | 2004-01-21 | |
| US57147104P | 2004-05-14 | 2004-05-14 | |
| PCT/US2005/004799 WO2005070086A2 (en) | 2004-01-21 | 2005-01-20 | Methods and compositions for determining a graft tolerant phenotype in a subject |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE557101T1 true ATE557101T1 (de) | 2012-05-15 |
Family
ID=34811352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05723099T ATE557101T1 (de) | 2004-01-21 | 2005-01-20 | Verfahren und zusammensetzungen zur bestimmung eines transplantationstoleranten phänotyps in einem individuum |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8932808B1 (de) |
| EP (1) | EP1718768B1 (de) |
| AT (1) | ATE557101T1 (de) |
| CA (2) | CA2553551C (de) |
| WO (1) | WO2005070086A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE46843E1 (en) | 2005-03-14 | 2018-05-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
| EP2604703B1 (de) * | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur Bewertung der Haltbarkeit eines Pfropfs im Körper eines Empfängers fester Organtransplantate |
| CA2653071A1 (en) | 2006-05-25 | 2007-12-06 | Sophie Brouard | Methods for diagnosing and treating graft rejection and inflammatory conditions |
| EP2066809A2 (de) * | 2006-08-28 | 2009-06-10 | Source Precision Medicine | Genexpressionsprofilierung zur identifikation, überwachung und behandlung einer transplantatabstossung |
| US20080131441A1 (en) * | 2006-09-26 | 2008-06-05 | Manikkam Suthanthiran | Methods of Using FOXP3 Levels to Predict the Outcome of Organs Undergoing Acute Rejection |
| EP1990425A1 (de) * | 2007-05-10 | 2008-11-12 | Tcland R | Diagnose von Immuntransplantatstoleranz |
| EP2088205A1 (de) | 2008-02-11 | 2009-08-12 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | PSMB10: Diagnosemarker und therapeutisches Target für chronische Abstoßung |
| WO2010021696A1 (en) | 2008-08-18 | 2010-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| WO2010070043A1 (en) * | 2008-12-19 | 2010-06-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Biomarkers for the diagnosis of renal allograft and kidney status |
| ES2492498T3 (es) | 2009-01-15 | 2014-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Panel de biomarcadores para el diagnóstico y la predicción de rechazo de injerto |
| EP2507630B1 (de) | 2009-12-02 | 2017-01-25 | The Board of Trustees of The Leland Stanford Junior University | Biomarker zur bestimmung eines allotransplantattoleranten phänotyps |
| WO2011119980A1 (en) | 2010-03-25 | 2011-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Protein and gene biomarkers for rejection of organ transplants |
| US8962261B2 (en) | 2011-04-06 | 2015-02-24 | The Board Of Trustees Of The Leland Stanford Junior University | Autoantibody biomarkers for IGA nephropathy |
| WO2014036444A1 (en) * | 2012-08-30 | 2014-03-06 | Abbott Laboratories | Prame detection assays |
| WO2016048388A1 (en) | 2014-09-26 | 2016-03-31 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994076A (en) | 1997-05-21 | 1999-11-30 | Clontech Laboratories, Inc. | Methods of assaying differential expression |
| US20030104371A1 (en) | 1997-09-24 | 2003-06-05 | Strom Terry B. | Methods of evaluating transplant rejection |
| US6607879B1 (en) | 1998-02-09 | 2003-08-19 | Incyte Corporation | Compositions for the detection of blood cell and immunological response gene expression |
| ATE396399T1 (de) | 1998-03-31 | 2008-06-15 | Asahi Kasei Pharma Corp | Verfahren zur untersuchung der iga-nephropathie |
| US20030113744A1 (en) | 2001-05-11 | 2003-06-19 | O' Toole Margot M. | Methods for diagnosing and treating ischemia and reperfusion injury and compositions thereof |
| US7026121B1 (en) | 2001-06-08 | 2006-04-11 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| AU2003291134A1 (en) | 2002-11-21 | 2004-06-18 | Genzyme Corporation | Use of diamide derivatives for inhibiting chronic tissue transplant rejection |
| CA2516013C (en) | 2003-02-14 | 2014-05-13 | Beth Israel Deaconess Medical Center, Inc. | Predicting graft rejection |
| US7892745B2 (en) | 2003-04-24 | 2011-02-22 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| JP4717810B2 (ja) | 2003-06-20 | 2011-07-06 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション インコーポレイテッド | 1型糖尿病と2型糖尿病を識別するためのバイオマーカー |
| WO2005054503A2 (en) | 2003-12-03 | 2005-06-16 | Novartis Ag | Biomarkers for graft rejection |
| BRPI0509754A (pt) | 2004-04-08 | 2007-10-16 | Novartis Ag | inibidores de proteìna quinase c para o tratamento de doenças auto-imunes e de rejeição a transplante |
| US7820382B2 (en) | 2004-08-03 | 2010-10-26 | Bauer A Robert | Method for the early detection of breast cancer, lung cancer, pancreatic cancer and colon polyps, growths and cancers as well as other gastrointestinal disease conditions and the preoperative and postoperative monitoring of transplanted organs from the donor and in the recipient and their associated conditions related and unrelated to the organ transplantation |
| EP2604703B1 (de) * | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur Bewertung der Haltbarkeit eines Pfropfs im Körper eines Empfängers fester Organtransplantate |
| US7666596B2 (en) | 2005-05-23 | 2010-02-23 | University Of Alberta | Tissue rejection |
| EP1731620A1 (de) | 2005-06-07 | 2006-12-13 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methode zur Diagnose von Immun-Transplantatstoleranz |
| ES2624863T3 (es) | 2005-06-08 | 2017-07-17 | Millennium Pharmaceuticals, Inc. | Métodos para identificación, evaluación, y tratamiento de pacientes con terapia de cáncer |
| WO2007050588A2 (en) | 2005-10-25 | 2007-05-03 | Renovar Incorporated | Systems and methods for characterizing conditions of organs for transplantation |
| CN101416063A (zh) | 2006-02-06 | 2009-04-22 | 拉帕波特家族医学科学研究所 | 用于诊断t1dm的方法和试剂盒 |
| GB0605217D0 (en) | 2006-03-15 | 2006-04-26 | Novartis Ag | Method and compositions for assessing acute rejection |
| GB0607943D0 (en) | 2006-04-21 | 2006-05-31 | Novartis Ag | Biomarkers for chronic transplant dysfunction |
| CA2650507A1 (en) | 2006-04-27 | 2007-11-08 | Universite De Montreal | Assessment and reduction of risk of graft-versus-host disease |
| WO2008084331A2 (en) | 2006-06-21 | 2008-07-17 | Hopitaux Universitaires De Geneve | Biomarkers for renal disorders |
| EP2049713A4 (de) | 2006-07-21 | 2010-06-16 | Univ Alberta | Gewebeabstossung |
| EP2066809A2 (de) | 2006-08-28 | 2009-06-10 | Source Precision Medicine | Genexpressionsprofilierung zur identifikation, überwachung und behandlung einer transplantatabstossung |
| US20110189680A1 (en) | 2008-05-30 | 2011-08-04 | The University Of British Columbia | Methods of Diagnosing Rejection of a Kidney Allograft Using Genomic or Proteomic Expression Profiling |
| CN102124340B (zh) | 2008-06-02 | 2014-12-17 | 卫材R&D管理有限公司 | IgA肾病的检查方法和检查试剂盒 |
| WO2010021696A1 (en) | 2008-08-18 | 2010-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| KR100928403B1 (ko) | 2008-10-01 | 2009-11-26 | 경북대학교 산학협력단 | 티지비엠 신증의 진단용 조성물 및 키트 |
| JP2013528799A (ja) | 2010-05-13 | 2013-07-11 | ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 神経変性疾患の検知および診断のための診断用自己抗体プロファイル |
-
2005
- 2005-01-20 WO PCT/US2005/004799 patent/WO2005070086A2/en not_active Ceased
- 2005-01-20 US US10/585,610 patent/US8932808B1/en active Active
- 2005-01-20 CA CA2553551A patent/CA2553551C/en not_active Expired - Fee Related
- 2005-01-20 AT AT05723099T patent/ATE557101T1/de active
- 2005-01-20 EP EP05723099A patent/EP1718768B1/de not_active Expired - Lifetime
- 2005-01-20 CA CA2957704A patent/CA2957704A1/en not_active Abandoned
-
2014
- 2014-02-27 US US14/192,696 patent/US20140206566A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2553551A1 (en) | 2005-08-04 |
| WO2005070086A3 (en) | 2006-09-14 |
| CA2553551C (en) | 2020-12-15 |
| CA2957704A1 (en) | 2005-08-04 |
| EP1718768B1 (de) | 2012-05-09 |
| WO2005070086A2 (en) | 2005-08-04 |
| US20140206566A1 (en) | 2014-07-24 |
| US8932808B1 (en) | 2015-01-13 |
| EP1718768A4 (de) | 2007-10-17 |
| EP1718768A2 (de) | 2006-11-08 |
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