ATE59968T1 - Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff. - Google Patents
Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff.Info
- Publication number
- ATE59968T1 ATE59968T1 AT87307696T AT87307696T ATE59968T1 AT E59968 T1 ATE59968 T1 AT E59968T1 AT 87307696 T AT87307696 T AT 87307696T AT 87307696 T AT87307696 T AT 87307696T AT E59968 T1 ATE59968 T1 AT E59968T1
- Authority
- AT
- Austria
- Prior art keywords
- transdermal delivery
- delivery device
- adhesive
- level
- eva
- Prior art date
Links
- 239000000853 adhesive Substances 0.000 title abstract 3
- 230000001070 adhesive effect Effects 0.000 title abstract 2
- 230000037317 transdermal delivery Effects 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000002480 mineral oil Substances 0.000 abstract 2
- 235000010446 mineral oil Nutrition 0.000 abstract 2
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 abstract 1
- 229930003347 Atropine Natural products 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 abstract 1
- 229920002367 Polyisobutene Polymers 0.000 abstract 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 abstract 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 abstract 1
- 229960000396 atropine Drugs 0.000 abstract 1
- 229960004605 timolol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coating Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/903,002 US4938759A (en) | 1986-09-02 | 1986-09-02 | Transdermal delivery device having a rate controlling adhesive |
| EP87307696A EP0259136B1 (de) | 1986-09-02 | 1987-09-01 | Transdermale Abgabevorrichtung mit Gradkontrollierendem Klebstoff |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE59968T1 true ATE59968T1 (de) | 1991-02-15 |
Family
ID=25416765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87307696T ATE59968T1 (de) | 1986-09-02 | 1987-09-01 | Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4938759A (de) |
| EP (1) | EP0259136B1 (de) |
| JP (1) | JP2511472B2 (de) |
| AT (1) | ATE59968T1 (de) |
| CA (1) | CA1297754C (de) |
| DE (1) | DE3767412D1 (de) |
| ES (1) | ES2020278B3 (de) |
| GR (1) | GR3001328T3 (de) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4725439A (en) * | 1984-06-29 | 1988-02-16 | Alza Corporation | Transdermal drug delivery device |
| JPS6468316A (en) * | 1987-09-08 | 1989-03-14 | Teikoku Seiyaku Kk | External plaster containing salbutamol |
| JPH0725669B2 (ja) * | 1988-12-23 | 1995-03-22 | 日東電工株式会社 | 経皮投与用医薬製剤 |
| US5788983A (en) * | 1989-04-03 | 1998-08-04 | Rutgers, The State University Of New Jersey | Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes |
| NZ237241A (en) * | 1990-03-02 | 1993-11-25 | Pharmetrix Corp | Method for increasing the storage stability of physostigmine |
| US5513660A (en) * | 1990-12-31 | 1996-05-07 | Uromed Corporation | Expandable urethral plug |
| US5479945A (en) * | 1990-12-31 | 1996-01-02 | Uromed Corporation | Method and a removable device which can be used for the self-administered treatment of urinary tract infections or other disorders |
| US5724994A (en) * | 1990-12-31 | 1998-03-10 | Uromed Corporation | Fluidly expandable urethral plug assembly which receives fluid from an external source and method for controlling urinary incontinence |
| US5509427A (en) * | 1990-12-31 | 1996-04-23 | Uromed Corporation | Urethral plug assembly having adhesive for enhanced sealing capabilities and method of using said plug assembly |
| US5518734A (en) * | 1991-09-25 | 1996-05-21 | Beta Pharmaceuticals Co. | Transdermal delivery system for estradiol and process for manufacturing said device |
| US5705185A (en) * | 1991-09-25 | 1998-01-06 | Beta Pharmaceuticals Co. | Transdermal delivery of estradiol and process for manufacturing said device |
| US5613958A (en) * | 1993-05-12 | 1997-03-25 | Pp Holdings Inc. | Transdermal delivery systems for the modulated administration of drugs |
| US5769091A (en) * | 1993-09-20 | 1998-06-23 | Uromed Corporation | Urethral plug having adhesive for enhanced sealing capabilities and method of using said plug |
| ES2172584T3 (es) * | 1994-05-18 | 2002-10-01 | Hisamitsu Pharmaceutical Co | Preparacion administrable por via percutanea para tratar trastornos de la miccion. |
| TW592729B (en) * | 1995-04-06 | 2004-06-21 | Janssen Pharmaceutica Nv | Rate-controlled transdermal administration of risperidone |
| US5840327A (en) * | 1995-08-21 | 1998-11-24 | Alza Corporation | Transdermal drug delivery device having enhanced adhesion |
| US5660431A (en) * | 1996-07-09 | 1997-08-26 | Leach; Thomas R. | Rocker conversion for lawn-type chairs |
| US6512010B1 (en) | 1996-07-15 | 2003-01-28 | Alza Corporation | Formulations for the administration of fluoxetine |
| US6203817B1 (en) | 1997-02-19 | 2001-03-20 | Alza Corporation | Reduction of skin reactions caused by transdermal drug delivery |
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US5965624A (en) * | 1997-06-27 | 1999-10-12 | Eval Company Of America | Self purging EVOH compositions, and methods |
| US6660295B2 (en) | 1997-09-30 | 2003-12-09 | Alza Corporation | Transdermal drug delivery device package with improved drug stability |
| JP2002517584A (ja) | 1998-06-11 | 2002-06-18 | ザ ダウ ケミカル カンパニー | アルファ−オレフィン/ビニル芳香族及び/又は脂肪族又は環式脂肪族ビニル又はビニリデンインターポリマーから製造される弾性フィルム |
| US6699497B1 (en) | 1998-07-24 | 2004-03-02 | Alza Corporation | Formulations for the transdermal administration of fenoldopam |
| US6348210B1 (en) | 1998-11-13 | 2002-02-19 | Alza Corporation | Methods for transdermal drug administration |
| NZ512432A (en) * | 1998-12-18 | 2003-10-31 | Alza Corp | Transparent transdermal nicotine delivery devices |
| US20030170195A1 (en) * | 2000-01-10 | 2003-09-11 | Noven Pharmaceuticals, Inc. | Compositions and methods for drug delivery |
| EP1061900B2 (de) * | 1999-01-14 | 2008-07-09 | Noven Pharmaceuticals, Inc. | Dermale zusammensetzungen |
| KR100622332B1 (ko) * | 1999-04-01 | 2006-09-13 | 알자 코포레이션 | 폴리우레탄 약물 리저버를 함유하는 경피 약물 수송 장치 |
| DE10033853A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| WO2003015678A1 (en) * | 2001-08-17 | 2003-02-27 | Lavipharm Laboratories Inc. | Composition and transdermal drug delivery device |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| AR033748A1 (es) * | 2002-05-15 | 2004-01-07 | Thalas Group Inc | Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo |
| US20040086551A1 (en) * | 2002-10-30 | 2004-05-06 | Miller Kenneth J. | Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl |
| WO2004075933A2 (en) * | 2003-02-26 | 2004-09-10 | Lavipharm S.A. | Devices for releasing volatile substances and methods of producing the devices |
| US20040258742A1 (en) * | 2003-04-11 | 2004-12-23 | Van Osdol William Woodson | Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines |
| CA2523859C (en) * | 2003-04-29 | 2011-08-02 | The General Hospital Corporation | Methods and devices for the sustained release of multiple drugs |
| EP1682061B1 (de) * | 2003-10-28 | 2017-03-15 | Noven Pharmaceuticals, Inc. | Transdermale arzneistoffabgabevorrichtung |
| US20050202073A1 (en) | 2004-03-09 | 2005-09-15 | Mylan Technologies, Inc. | Transdermal systems containing multilayer adhesive matrices to modify drug delivery |
| US9205062B2 (en) | 2004-03-09 | 2015-12-08 | Mylan Pharmaceuticals, Inc. | Transdermal systems containing multilayer adhesive matrices to modify drug delivery |
| US7591806B2 (en) * | 2004-05-18 | 2009-09-22 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| US20060078602A1 (en) | 2004-10-08 | 2006-04-13 | Noven Pharmaceuticals, Inc. | Device for transdermal administration of drugs including acrylic polymers |
| WO2006041907A2 (en) | 2004-10-08 | 2006-04-20 | Noven Pharmaceuticals, Inc. | Transdermal delivery of estradiol |
| EP1814531B1 (de) | 2004-10-21 | 2010-06-16 | Durect Corporation | Transdermale verabreichungssysteme |
| US8252320B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
| US8048017B2 (en) * | 2005-05-18 | 2011-11-01 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| US8043250B2 (en) * | 2005-05-18 | 2011-10-25 | Nanomed Devices, Inc. | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| WO2007121188A2 (en) * | 2006-04-10 | 2007-10-25 | Knopp Neurosciences, Inc. | Compositions and methods of using r(+) pramipexole |
| US8518926B2 (en) * | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| PL2026803T3 (pl) * | 2006-05-16 | 2012-05-31 | Knopp Neurosciences Inc | Kompozycje R(+) i S(-) pramipeksolu i sposoby ich zastosowania |
| PL2117521T3 (pl) | 2006-11-03 | 2012-11-30 | Durect Corp | Transdermalne systemy dostarczania zawierające bupiwakainę |
| US8524695B2 (en) * | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| US20080214987A1 (en) * | 2006-12-22 | 2008-09-04 | Nanomed Devices, Inc. | Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances |
| US10525246B2 (en) | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
| EP2137171A4 (de) | 2007-03-14 | 2010-05-19 | Knopp Neurosciences Inc | Synthese von chiralaufgereinigten substituierten benzothiazoldiaminen |
| US8231906B2 (en) | 2008-07-10 | 2012-07-31 | Noven Pharmaceuticals, Inc. | Transdermal estrogen device and delivery |
| US20110190356A1 (en) * | 2008-08-19 | 2011-08-04 | Knopp Neurosciences Inc. | Compositions and Methods of Using (R)- Pramipexole |
| AU2010262970A1 (en) * | 2009-06-19 | 2012-01-12 | Knopp Neurosciences, Inc. | Compositions and methods for treating amyotrophic lateral sclerosis |
| WO2011130455A1 (en) | 2010-04-13 | 2011-10-20 | Najib Babul | Dermal pharmaceutical compositions of 1-methyl-2',6'-pipecoloxylidide and method of use |
| WO2012096866A2 (en) | 2011-01-10 | 2012-07-19 | Inverseon, Inc. | Use of beta-adrenergic inverse agonists for smoking cessation |
| US9512096B2 (en) | 2011-12-22 | 2016-12-06 | Knopp Biosciences, LLP | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| WO2014188329A2 (en) | 2013-05-20 | 2014-11-27 | Mylan, Inc. | Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders |
| HRP20251187T1 (hr) | 2013-07-12 | 2025-11-21 | Areteia Therapeutics, Inc. | Liječenje povišenih razina eozinofila i/ili bazofila |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| US9642840B2 (en) | 2013-08-13 | 2017-05-09 | Knopp Biosciences, Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
| US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| US11103389B2 (en) * | 2015-01-30 | 2021-08-31 | Daio Paper Corporation | Absorbent article having stretchable region with high peeling strength and method for producing same |
| JP6240733B1 (ja) * | 2016-09-30 | 2017-11-29 | 大王製紙株式会社 | 使い捨て着用物品及びその製造方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
| US3598122A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3699963A (en) * | 1969-10-31 | 1972-10-24 | Alza Corp | Therapeutic adhesive patch |
| US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| US3742951A (en) * | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
| US3926188A (en) * | 1974-11-14 | 1975-12-16 | Alza Corp | Laminated drug dispenser |
| US4144317A (en) * | 1975-05-30 | 1979-03-13 | Alza Corporation | Device consisting of copolymer having acetoxy groups for delivering drugs |
| US4262003A (en) | 1975-12-08 | 1981-04-14 | Alza Corporation | Method and therapeutic system for administering scopolamine transdermally |
| US4031894A (en) * | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
| US4060084A (en) * | 1976-09-07 | 1977-11-29 | Alza Corporation | Method and therapeutic system for providing chemotherapy transdermally |
| US4286592A (en) * | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
| US4314557A (en) * | 1980-05-19 | 1982-02-09 | Alza Corporation | Dissolution controlled active agent dispenser |
| US4379454A (en) * | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
| US4605548A (en) * | 1983-05-31 | 1986-08-12 | Nitto Electric Industrial Co., Ltd. | Drug administration material |
| DE3347278A1 (de) * | 1983-12-28 | 1985-07-11 | Bayer Ag, 5090 Leverkusen | Wirkstoffabgabesysteme |
| US4752478A (en) * | 1984-12-17 | 1988-06-21 | Merck & Co., Inc. | Transdermal system for timolol |
| US4615699A (en) * | 1985-05-03 | 1986-10-07 | Alza Corporation | Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes |
-
1986
- 1986-09-02 US US07/903,002 patent/US4938759A/en not_active Expired - Lifetime
-
1987
- 1987-09-01 AT AT87307696T patent/ATE59968T1/de not_active IP Right Cessation
- 1987-09-01 CA CA000545836A patent/CA1297754C/en not_active Expired - Fee Related
- 1987-09-01 ES ES87307696T patent/ES2020278B3/es not_active Expired - Lifetime
- 1987-09-01 DE DE8787307696T patent/DE3767412D1/de not_active Expired - Fee Related
- 1987-09-01 EP EP87307696A patent/EP0259136B1/de not_active Expired - Lifetime
- 1987-09-02 JP JP62220072A patent/JP2511472B2/ja not_active Expired - Lifetime
-
1991
- 1991-01-17 GR GR90400474T patent/GR3001328T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0259136B1 (de) | 1991-01-16 |
| JP2511472B2 (ja) | 1996-06-26 |
| CA1297754C (en) | 1992-03-24 |
| US4938759A (en) | 1990-07-03 |
| ES2020278B3 (es) | 1991-08-01 |
| EP0259136A2 (de) | 1988-03-09 |
| DE3767412D1 (de) | 1991-02-21 |
| EP0259136A3 (en) | 1989-03-15 |
| JPS63119421A (ja) | 1988-05-24 |
| GR3001328T3 (en) | 1992-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |