ATE63563T1 - Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number: ATE63563T1
Authority: AT; Austria
Prior art keywords: derivatives; synergist; production; pharmaceutical compositions; formula
Prior art date: 1986-05-22

Application number

AT87401142T

Other languages

English (en)

Inventor

Jean-Claude Barriere

Claude Cotrel

Jean-Marc Paris

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-05-22

Filing date

1987-05-21

Publication date

1991-06-15

1987-05-21 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1991-06-15 Application granted granted Critical

1991-06-15 Publication of ATE63563T1 publication Critical patent/ATE63563T1/de

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
108010015791 Streptogramin A Proteins 0.000 abstract 2
SUJXEPROYKNZJB-UHFFFAOYSA-N 1-azabicyclo[2.2.2]octane-2-thiol Chemical compound C1CN2C(S)CC1CC2 SUJXEPROYKNZJB-UHFFFAOYSA-N 0.000 abstract 1
YVMBAUWDIGJRNY-BESUKNQGSA-N 4o8o7q7iu4 Chemical class C1C(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@@H](C)[C@@H](C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2.N([C@@H]1C(=O)N[C@@H](C(N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(=CC=2)N(C)C)C(=O)N2CCC(=O)C[C@H]2C(=O)N[C@H](C(=O)O[C@@H]1C)C=1C=CC=CC=1)=O)CC)C(=O)C1=NC=CC=C1O YVMBAUWDIGJRNY-BESUKNQGSA-N 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
DAIKHDNSXMZDCU-FQTGFAPKSA-N pristinamycin IIA Chemical compound C1C(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@@H](C)[C@@H](C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2 DAIKHDNSXMZDCU-FQTGFAPKSA-N 0.000 abstract 1
DAIKHDNSXMZDCU-UHFFFAOYSA-N pristinamycin component IIA Natural products C1C(=O)CC(O)C=C(C)C=CCNC(=O)C=CC(C)C(C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2 DAIKHDNSXMZDCU-UHFFFAOYSA-N 0.000 abstract 1
DAIKHDNSXMZDCU-OUDXUNEISA-N pristinamycin-IIA Natural products CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)C=C(C)C=CCNC(=O)C=C[C@@H]1C)n3 DAIKHDNSXMZDCU-OUDXUNEISA-N 0.000 abstract 1
JOOMGSFOCRDAHL-XKCHLWDXSA-N pristinamycin-IIB Natural products CC(C)[C@@H]1OC(=O)[C@H]2CCCN2C(=O)c3coc(CC(=O)C[C@@H](O)C=C(C)C=CCNC(=O)C=C[C@H]1C)n3 JOOMGSFOCRDAHL-XKCHLWDXSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Lubricants (AREA)
Vibration Prevention Devices (AREA)
Measurement Of Force In General (AREA)
Polarising Elements (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

AT87401142T 1986-05-22 1987-05-21 Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. ATE63563T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8607270A FR2599036B1 (fr)	1986-05-22	1986-05-22	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
EP87401142A EP0248703B1 (de)	1986-05-22	1987-05-21	Synergistin-Derivate, deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number	Publication Date
ATE63563T1 true ATE63563T1 (de)	1991-06-15

Family

ID=9335470

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87401142T ATE63563T1 (de)	1986-05-22	1987-05-21	Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (25)

Country	Link
US (1)	US4798827A (de)
EP (1)	EP0248703B1 (de)
JP (2)	JP2558282B2 (de)
KR (1)	KR950001020B1 (de)
AT (1)	ATE63563T1 (de)
AU (1)	AU601426B2 (de)
BR (1)	BR1101133A (de)
CA (1)	CA1271297A (de)
DE (2)	DE10075012I2 (de)
DK (1)	DK172949B1 (de)
ES (1)	ES2032457T3 (de)
FI (1)	FI84355C (de)
FR (1)	FR2599036B1 (de)
GE (1)	GEP19960474B (de)
GR (1)	GR3002558T3 (de)
IE (1)	IE60656B1 (de)
IL (1)	IL82564A (de)
LU (1)	LU90732I2 (de)
LV (1)	LV5268A3 (de)
MX (1)	MX9203577A (de)
NL (1)	NL300010I2 (de)
NZ (1)	NZ220380A (de)
PT (1)	PT84934B (de)
SU (1)	SU1616520A3 (de)
ZA (1)	ZA873639B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2664894A1 (fr) *	1990-07-19	1992-01-24	Rhone Poulenc Sante	Nouveaux derives de streptogramines et leur preparation.
FR2689518B1 (fr) *	1992-04-01	1995-04-07	Rhone Poulenc Rorer Sa	Microorganismes, procédé de préparation et utilisation.
US5242938A (en) *	1992-08-27	1993-09-07	Merck & Co., Inc.	Derivatives of virginiamycin M1
IL121821A (en) *	1993-02-17	2000-02-17	Rhone Poulenc Rorer Sa	Process for purifying a group A minority component of streptogramin some such purified components and their uses
FR2722210B1 (fr) *	1994-07-08	1996-08-14	Rhone Poulenc Rorer Sa	Nouvelles streptogramines et procede de preparation de streptogramines par mutasynthese
FR2723373B1 (fr)	1994-08-02	1996-09-13	Rhone Poulenc Rorer Sa	Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
FR2755857B1 (fr) *	1996-11-19	1998-12-24	Rhone Poulenc Rorer Sa	Compositions pharmaceutiques stabilisees, a base de quinupristine et de dalfopristine et leur preparation
FR2766489B1 (fr)	1997-07-28	1999-08-27	Rhone Poulenc Rorer Sa	Derives de streptogramines, leur preparation et les compositions qui les contiennent
US6187746B1 (en) *	1997-12-16	2001-02-13	Rhone-Poulenc Rorer S.A.	Pharmaceutical compositions based on dalfopristine and on quinupristine, and preparation thereof
FR2796949B1 (fr) *	1999-07-27	2001-09-21	Aventis Pharma Sa	Derives de streptogramines, leur preparation et les compositions qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2549065B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549063B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549064B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines utiles pour la preparation de nouveaux medicaments antimicrobiens et leur preparation
FR2549062B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr) *	1985-01-11	1987-09-11	Rhone Poulenc Sante	Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent

1986
- 1986-05-22 FR FR8607270A patent/FR2599036B1/fr not_active Expired
1987
- 1987-05-18 IL IL82564A patent/IL82564A/xx not_active IP Right Cessation
- 1987-05-20 AU AU73239/87A patent/AU601426B2/en not_active Expired
- 1987-05-20 ZA ZA873639A patent/ZA873639B/xx unknown
- 1987-05-20 NZ NZ220380A patent/NZ220380A/xx unknown
- 1987-05-20 IE IE131787A patent/IE60656B1/en not_active IP Right Cessation
- 1987-05-21 DK DK198702585A patent/DK172949B1/da active Protection Beyond IP Right Term
- 1987-05-21 US US07/052,371 patent/US4798827A/en not_active Expired - Lifetime
- 1987-05-21 ES ES198787401142T patent/ES2032457T3/es not_active Expired - Lifetime
- 1987-05-21 AT AT87401142T patent/ATE63563T1/de active
- 1987-05-21 CA CA000537562A patent/CA1271297A/fr not_active Expired - Lifetime
- 1987-05-21 FI FI872236A patent/FI84355C/fi not_active IP Right Cessation
- 1987-05-21 DE DE2000175012 patent/DE10075012I2/de active Active
- 1987-05-21 DE DE8787401142T patent/DE3770048D1/de not_active Expired - Lifetime
- 1987-05-21 SU SU874202596A patent/SU1616520A3/ru active
- 1987-05-21 KR KR1019870005111A patent/KR950001020B1/ko not_active Expired - Lifetime
- 1987-05-21 EP EP87401142A patent/EP0248703B1/de not_active Expired - Lifetime
- 1987-05-22 JP JP62125613A patent/JP2558282B2/ja not_active Expired - Fee Related
- 1987-05-22 PT PT84934A patent/PT84934B/pt unknown
1991
- 1991-05-20 GR GR90400906T patent/GR3002558T3/el unknown
1992
- 1992-06-26 MX MX9203577A patent/MX9203577A/es unknown
1993
- 1993-01-26 LV LV930070A patent/LV5268A3/xx unknown
- 1993-07-31 GE GEAP19931362A patent/GEP19960474B/en unknown
1996
- 1996-04-30 JP JP8130555A patent/JP2659531B2/ja not_active Expired - Fee Related
1997
- 1997-05-14 BR BR1101133-5A patent/BR1101133A/pt active IP Right Grant
2000
- 2000-06-16 NL NL300010C patent/NL300010I2/nl unknown
2001
- 2001-02-16 LU LU90732C patent/LU90732I2/en unknown

Also Published As

Publication number	Publication date
FI84355B (fi)	1991-08-15
DK258587A (da)	1987-11-23
FR2599036A1 (fr)	1987-11-27
ES2032457T3 (es)	1993-02-16
GEP19960474B (en)	1996-07-22
IL82564A0 (en)	1987-11-30
PT84934B (pt)	1990-02-08
SU1616520A3 (ru)	1990-12-23
US4798827A (en)	1989-01-17
NL300010I2 (nl)	2001-01-02
DE10075012I1 (de)	2000-08-31
JPS6322095A (ja)	1988-01-29
JP2558282B2 (ja)	1996-11-27
ZA873639B (en)	1987-11-17
JPH08319236A (ja)	1996-12-03
DK172949B1 (da)	1999-10-11
MX9203577A (es)	1992-09-01
FI872236L (fi)	1987-11-23
LU90732I2 (en)	2001-04-17
NL300010I1 (nl)	2000-08-01
KR880013934A (ko)	1988-12-22
IE60656B1 (en)	1994-08-10
LV5268A3 (lv)	1993-10-10
CA1271297A (fr)	1990-07-03
AU7323987A (en)	1987-11-26
FI872236A0 (fi)	1987-05-21
DE10075012I2 (de)	2006-02-02
PT84934A (fr)	1987-06-01
IE871317L (en)	1987-11-22
EP0248703A1 (de)	1987-12-09
GR3002558T3 (en)	1993-01-25
EP0248703B1 (de)	1991-05-15
DE3770048D1 (de)	1991-06-20
NZ220380A (en)	1989-02-24
KR950001020B1 (ko)	1995-02-07
FI84355C (fi)	1991-11-25
BR1101133A (pt)	1999-12-07
FR2599036B1 (fr)	1988-09-09
DK258587D0 (da)	1987-05-21
AU601426B2 (en)	1990-09-13
JP2659531B2 (ja)	1997-09-30
IL82564A (en)	1991-04-15

Publication	Publication Date	Title
MX9200269A (es)	1992-07-01	Derivados de bifenilo, medicamentos que contienen estos compuestos y procedimientos para su preparacion
NO940523D0 (no)	1994-02-15	Nye pyrazin-derivater
DE3770048D1 (de)	1991-06-20	Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
GR3019274T3 (en)	1996-06-30	Substituted 3-piperazinylalkyl-2,3-dihydro-4H-1,3-benzoxazine-4-ones, their preparation and their therapeutical use
AU611113B2 (en)	1991-06-06	Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
SE8603589L (sv)	1987-03-01	Metylendioxifenantren- och stilbenderivat
DE69403110D1 (de)	1997-06-19	Zyklische Angiopeptin Derivate, deren Herstellung und pharmazeutische Zusammensetzungen
ES2106866T3 (es)	1997-11-16	Nuevos derivados de 2h-benzo(b)pirano sustituidos en la posicion 4 por arilo o n-heteroarilo, procedimiento para su preparacion y su uso, asi como preparados que contienen los compuestos.
DK222588A (da)	1988-10-26	5-quinoxalyl-imidazolidin-2,4-dioner, deres fremstilling og anvendelse som laegemidler
MX9303392A (es)	1994-06-30	Derivados de imidazo benzoxazin-1-ona substituidos y proceso para su preparacion.
NO903291D0 (no)	1990-07-24	Renin-hemmende aminooligohydroksy-derivater.
DE69222143D1 (de)	1997-10-16	Indanderivate
ES2065192T3 (es)	1995-02-01	Nuevos nicotinatos de diacil-glicerol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
DK0466586T3 (da)	1995-04-03	Disubstituerede polymethyleniminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
DK0418990T3 (da)	1994-03-14	13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
AR029415A1 (es)	2003-06-25	Pirroles sustituidos, un procedimiento para su preparacion, composicion farmaceutica, y el uso de dichos compuestos para la preparacion de medicamentos
IL67400A0 (en)	1983-05-15	3,7alpha-diazacyclohepta(j,k)fluorene derivatives,their preparation and pharmaceutical compositions containing them
SE8903313L (sv)	1990-04-12	Nya 2-metoxikarbonyl-substituerade n,n'-di-(trimetoxibensoyl)-piperaziner, foerfarande foer framstaellning daerav och terapeutiska foereningar innehaallande dem
ES2123038T3 (es)	1999-01-01	Nuevos derivados pirrolo-tieno-pirazinicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
ES2132287T3 (es)	1999-08-16	Salmicinas, un procedimiento para su preparacion y su uso como producto farmaceutico.