IL82564A - Synergistin derivatives,their preparation and pharmaceutical compositions which contain them - Google Patents

Synergistin derivatives,their preparation and pharmaceutical compositions which contain them

Info

Publication number: IL82564A
Authority: IL; Israel
Prior art keywords: preparation; contain; pharmaceutical compositions; formula; synergistin derivatives
Prior art date: 1986-05-22

Application number

IL82564A

Other languages

English (en)

Other versions

IL82564A0 (en

Original Assignee

Rhone Poulenc Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-05-22

Filing date

1987-05-18

Publication date

1991-04-15

1987-05-18 Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante

1987-11-30 Publication of IL82564A0 publication Critical patent/IL82564A0/xx

1991-04-15 Publication of IL82564A publication Critical patent/IL82564A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
108010015791 Streptogramin A Proteins 0.000 abstract 2
SUJXEPROYKNZJB-UHFFFAOYSA-N 1-azabicyclo[2.2.2]octane-2-thiol Chemical compound C1CN2C(S)CC1CC2 SUJXEPROYKNZJB-UHFFFAOYSA-N 0.000 abstract 1
YVMBAUWDIGJRNY-BESUKNQGSA-N 4o8o7q7iu4 Chemical class C1C(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@@H](C)[C@@H](C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2.N([C@@H]1C(=O)N[C@@H](C(N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(=CC=2)N(C)C)C(=O)N2CCC(=O)C[C@H]2C(=O)N[C@H](C(=O)O[C@@H]1C)C=1C=CC=CC=1)=O)CC)C(=O)C1=NC=CC=C1O YVMBAUWDIGJRNY-BESUKNQGSA-N 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
DAIKHDNSXMZDCU-FQTGFAPKSA-N pristinamycin IIA Chemical compound C1C(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@@H](C)[C@@H](C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2 DAIKHDNSXMZDCU-FQTGFAPKSA-N 0.000 abstract 1
DAIKHDNSXMZDCU-UHFFFAOYSA-N pristinamycin component IIA Natural products C1C(=O)CC(O)C=C(C)C=CCNC(=O)C=CC(C)C(C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2 DAIKHDNSXMZDCU-UHFFFAOYSA-N 0.000 abstract 1
DAIKHDNSXMZDCU-OUDXUNEISA-N pristinamycin-IIA Natural products CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)C=C(C)C=CCNC(=O)C=C[C@@H]1C)n3 DAIKHDNSXMZDCU-OUDXUNEISA-N 0.000 abstract 1
JOOMGSFOCRDAHL-XKCHLWDXSA-N pristinamycin-IIB Natural products CC(C)[C@@H]1OC(=O)[C@H]2CCCN2C(=O)c3coc(CC(=O)C[C@@H](O)C=C(C)C=CCNC(=O)C=C[C@H]1C)n3 JOOMGSFOCRDAHL-XKCHLWDXSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Lubricants (AREA)
Vibration Prevention Devices (AREA)
Measurement Of Force In General (AREA)
Polarising Elements (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

IL82564A 1986-05-22 1987-05-18 Synergistin derivatives,their preparation and pharmaceutical compositions which contain them IL82564A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8607270A FR2599036B1 (fr)	1986-05-22	1986-05-22	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number	Publication Date
IL82564A0 IL82564A0 (en)	1987-11-30
IL82564A true IL82564A (en)	1991-04-15

Family

ID=9335470

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL82564A IL82564A (en)	1986-05-22	1987-05-18	Synergistin derivatives,their preparation and pharmaceutical compositions which contain them

Country Status (25)

Country	Link
US (1)	US4798827A (de)
EP (1)	EP0248703B1 (de)
JP (2)	JP2558282B2 (de)
KR (1)	KR950001020B1 (de)
AT (1)	ATE63563T1 (de)
AU (1)	AU601426B2 (de)
BR (1)	BR1101133A (de)
CA (1)	CA1271297A (de)
DE (2)	DE10075012I2 (de)
DK (1)	DK172949B1 (de)
ES (1)	ES2032457T3 (de)
FI (1)	FI84355C (de)
FR (1)	FR2599036B1 (de)
GE (1)	GEP19960474B (de)
GR (1)	GR3002558T3 (de)
IE (1)	IE60656B1 (de)
IL (1)	IL82564A (de)
LU (1)	LU90732I2 (de)
LV (1)	LV5268A3 (de)
MX (1)	MX9203577A (de)
NL (1)	NL300010I2 (de)
NZ (1)	NZ220380A (de)
PT (1)	PT84934B (de)
SU (1)	SU1616520A3 (de)
ZA (1)	ZA873639B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2664894A1 (fr) *	1990-07-19	1992-01-24	Rhone Poulenc Sante	Nouveaux derives de streptogramines et leur preparation.
FR2689518B1 (fr) *	1992-04-01	1995-04-07	Rhone Poulenc Rorer Sa	Microorganismes, procédé de préparation et utilisation.
US5242938A (en) *	1992-08-27	1993-09-07	Merck & Co., Inc.	Derivatives of virginiamycin M1
IL121821A (en) *	1993-02-17	2000-02-17	Rhone Poulenc Rorer Sa	Process for purifying a group A minority component of streptogramin some such purified components and their uses
FR2722210B1 (fr) *	1994-07-08	1996-08-14	Rhone Poulenc Rorer Sa	Nouvelles streptogramines et procede de preparation de streptogramines par mutasynthese
FR2723373B1 (fr)	1994-08-02	1996-09-13	Rhone Poulenc Rorer Sa	Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
FR2755857B1 (fr) *	1996-11-19	1998-12-24	Rhone Poulenc Rorer Sa	Compositions pharmaceutiques stabilisees, a base de quinupristine et de dalfopristine et leur preparation
FR2766489B1 (fr)	1997-07-28	1999-08-27	Rhone Poulenc Rorer Sa	Derives de streptogramines, leur preparation et les compositions qui les contiennent
US6187746B1 (en) *	1997-12-16	2001-02-13	Rhone-Poulenc Rorer S.A.	Pharmaceutical compositions based on dalfopristine and on quinupristine, and preparation thereof
FR2796949B1 (fr) *	1999-07-27	2001-09-21	Aventis Pharma Sa	Derives de streptogramines, leur preparation et les compositions qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2549065B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549063B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549064B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines utiles pour la preparation de nouveaux medicaments antimicrobiens et leur preparation
FR2549062B1 (fr) *	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr) *	1985-01-11	1987-09-11	Rhone Poulenc Sante	Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent

1986
- 1986-05-22 FR FR8607270A patent/FR2599036B1/fr not_active Expired
1987
- 1987-05-18 IL IL82564A patent/IL82564A/xx not_active IP Right Cessation
- 1987-05-20 AU AU73239/87A patent/AU601426B2/en not_active Expired
- 1987-05-20 ZA ZA873639A patent/ZA873639B/xx unknown
- 1987-05-20 NZ NZ220380A patent/NZ220380A/xx unknown
- 1987-05-20 IE IE131787A patent/IE60656B1/en not_active IP Right Cessation
- 1987-05-21 DK DK198702585A patent/DK172949B1/da active Protection Beyond IP Right Term
- 1987-05-21 US US07/052,371 patent/US4798827A/en not_active Expired - Lifetime
- 1987-05-21 ES ES198787401142T patent/ES2032457T3/es not_active Expired - Lifetime
- 1987-05-21 AT AT87401142T patent/ATE63563T1/de active
- 1987-05-21 CA CA000537562A patent/CA1271297A/fr not_active Expired - Lifetime
- 1987-05-21 FI FI872236A patent/FI84355C/fi not_active IP Right Cessation
- 1987-05-21 DE DE2000175012 patent/DE10075012I2/de active Active
- 1987-05-21 DE DE8787401142T patent/DE3770048D1/de not_active Expired - Lifetime
- 1987-05-21 SU SU874202596A patent/SU1616520A3/ru active
- 1987-05-21 KR KR1019870005111A patent/KR950001020B1/ko not_active Expired - Lifetime
- 1987-05-21 EP EP87401142A patent/EP0248703B1/de not_active Expired - Lifetime
- 1987-05-22 JP JP62125613A patent/JP2558282B2/ja not_active Expired - Fee Related
- 1987-05-22 PT PT84934A patent/PT84934B/pt unknown
1991
- 1991-05-20 GR GR90400906T patent/GR3002558T3/el unknown
1992
- 1992-06-26 MX MX9203577A patent/MX9203577A/es unknown
1993
- 1993-01-26 LV LV930070A patent/LV5268A3/xx unknown
- 1993-07-31 GE GEAP19931362A patent/GEP19960474B/en unknown
1996
- 1996-04-30 JP JP8130555A patent/JP2659531B2/ja not_active Expired - Fee Related
1997
- 1997-05-14 BR BR1101133-5A patent/BR1101133A/pt active IP Right Grant
2000
- 2000-06-16 NL NL300010C patent/NL300010I2/nl unknown
2001
- 2001-02-16 LU LU90732C patent/LU90732I2/en unknown

Also Published As

Publication number	Publication date
FI84355B (fi)	1991-08-15
DK258587A (da)	1987-11-23
FR2599036A1 (fr)	1987-11-27
ES2032457T3 (es)	1993-02-16
GEP19960474B (en)	1996-07-22
IL82564A0 (en)	1987-11-30
PT84934B (pt)	1990-02-08
SU1616520A3 (ru)	1990-12-23
US4798827A (en)	1989-01-17
NL300010I2 (nl)	2001-01-02
DE10075012I1 (de)	2000-08-31
JPS6322095A (ja)	1988-01-29
JP2558282B2 (ja)	1996-11-27
ZA873639B (en)	1987-11-17
JPH08319236A (ja)	1996-12-03
DK172949B1 (da)	1999-10-11
MX9203577A (es)	1992-09-01
FI872236L (fi)	1987-11-23
LU90732I2 (en)	2001-04-17
NL300010I1 (nl)	2000-08-01
KR880013934A (ko)	1988-12-22
IE60656B1 (en)	1994-08-10
LV5268A3 (lv)	1993-10-10
CA1271297A (fr)	1990-07-03
AU7323987A (en)	1987-11-26
FI872236A0 (fi)	1987-05-21
DE10075012I2 (de)	2006-02-02
PT84934A (fr)	1987-06-01
IE871317L (en)	1987-11-22
EP0248703A1 (de)	1987-12-09
GR3002558T3 (en)	1993-01-25
EP0248703B1 (de)	1991-05-15
DE3770048D1 (de)	1991-06-20
NZ220380A (en)	1989-02-24
KR950001020B1 (ko)	1995-02-07
FI84355C (fi)	1991-11-25
BR1101133A (pt)	1999-12-07
FR2599036B1 (fr)	1988-09-09
DK258587D0 (da)	1987-05-21
ATE63563T1 (de)	1991-06-15
AU601426B2 (en)	1990-09-13
JP2659531B2 (ja)	1997-09-30

Legal Events

Date	Code	Title
1997-09-30	KB	Patent renewed
2001-04-30	PEL	Intention of commissioner to extend period of protection
2001-07-24	KB	Patent renewed
2002-02-10	EXTG	Extension of patent term granted
2005-07-25	MM9K	Patent not in force due to non-payment of renewal fees
2006-12-27	EXTN	Extension order renewed
2007-07-24	EXP	Patent expired
2009-05-03	KB20	Patent renewed for 20 years
2010-05-17	EXTN	Extension order renewed
2010-12-30	EXTN	Extension order renewed
2013-05-30	EXP	Patent expired

Publication	Publication Date	Title
IL101819A0 (en)	1992-12-30	Amidinophenylalanine derivatives,a process for the preparation thereof,use thereof and agents containing these as anticoagulants
HUP0004040A1 (hu)	2001-05-28	Antimikrobiális hatású pleuromutilinszármazékok, eljárás ezek előállítására, ezeket tartalmazó gyógyászati készítmények és alkalmazásuk
NO301419B1 (no)	1997-10-27	2-okso-5-oksazolidinmetylforbindelser, farmasöytiske preparater som inneholder slike, og anvendelse derav for fremstilling av legemidler
HUT68963A (en)	1995-08-28	Novel 4-arylpiperazines and 4-arylpiperidines, pharmaceutical compositions comprising them and the proces for producing thereof
ZA875179B (en)	1988-03-30	Taxol derivatives,their preparation and pharmaceutical compositions containing them
IL82564A0 (en)	1987-11-30	Synergistin derivatives,their preparation and pharmaceutical compositions which contain them
IL78691A (en)	1989-09-28	Quinolylglycinamide derivatives,their preparation and pharmaceutical compositions containing them
AU611113B2 (en)	1991-06-06	Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
IL113365A0 (en)	1995-07-31	5-heterocyclo-1,5-benzodiazepine derivatives, their preparation and use and pharmaceutical compositions containing them
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
HUT39147A (en)	1986-08-28	Process for preparing phenoxy-propanol-acethylene derivatives and pharmaceutical compositions containing such compounds
HUT49876A (en)	1989-11-28	Process for producing 6-oxopyridazine derivatives and pharmaceutical compositions comprising same
DK0443957T3 (da)	1995-07-10	Hidtil ukendte steroid-forbindelser med en spirogruppe i position 17, en fremgangsmåde og mellemprodukter til fremstilling deraf, deres anvendelse som lægemiddel og farmaceutiske præparater med indhold deraf
MX9303392A (es)	1994-06-30	Derivados de imidazo benzoxazin-1-ona substituidos y proceso para su preparacion.
ZA921735B (en)	1993-01-27	Indane derivatives
IL86722A0 (en)	1988-11-30	Guanidine-related compounds comprising a tetraphenylborate ion,their preparation and their use
ES2023760A6 (es)	1992-02-01	Procedimiento para la preparacion de derivados benzotiazinicos.
IL95384A0 (en)	1991-06-30	1,3-oxazines,their preparation and pharmaceutical compositions containing them
IT1252568B (it)	1995-06-19	Derivati pirimidinici sostituiti da eteroarili ad attivita' a ii antagonista