ATE63817T1 - Mischungen von fu und bvu als adenokarzinomhemmende mittel. - Google Patents

Mischungen von fu und bvu als adenokarzinomhemmende mittel.

Info

Publication number: ATE63817T1
Authority: AT; Austria
Prior art keywords: bvu; adenocarcinoma; mixtures; agents; bromovinyl
Prior art date: 1987-02-13

Application number

AT88200265T

Other languages

English (en)

Inventor

Clercq Erik De

Masaaki Iigo

Original Assignee

Stichting Rega V Z W

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-13

Filing date

1988-02-12

Publication date

1991-06-15

1988-02-12 Application filed by Stichting Rega V Z W filed Critical Stichting Rega V Z W

1991-06-15 Application granted granted Critical

1991-06-15 Publication of ATE63817T1 publication Critical patent/ATE63817T1/de

Links

239000000203 mixture Substances 0.000 title abstract 3
208000009956 adenocarcinoma Diseases 0.000 title abstract 2
239000002243 precursor Substances 0.000 abstract 2
BLXGZIDBSXVMLU-OWOJBTEDSA-N 5-[(e)-2-bromoethenyl]-1h-pyrimidine-2,4-dione Chemical compound Br\C=C\C1=CNC(=O)NC1=O BLXGZIDBSXVMLU-OWOJBTEDSA-N 0.000 abstract 1
GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229960002949 fluorouracil Drugs 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT88200265T 1987-02-13 1988-02-12 Mischungen von fu und bvu als adenokarzinomhemmende mittel. ATE63817T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL8700366A NL8700366A (nl)	1987-02-13	1987-02-13	Combinatie van fu met bvdu als middel tegen adenocarcinoom.
EP88200265A EP0283065B1 (de)	1987-02-13	1988-02-12	Mischungen von FU und BVU als adenokarzinomhemmende Mittel

Publications (1)

Publication Number	Publication Date
ATE63817T1 true ATE63817T1 (de)	1991-06-15

Family

ID=19849574

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88200265T ATE63817T1 (de)	1987-02-13	1988-02-12	Mischungen von fu und bvu als adenokarzinomhemmende mittel.

Country Status (8)

Country	Link
US (2)	US4894365A (de)
EP (1)	EP0283065B1 (de)
JP (1)	JP2688057B2 (de)
AT (1)	ATE63817T1 (de)
DE (1)	DE3862961D1 (de)
ES (1)	ES2032942T3 (de)
GR (1)	GR3002431T3 (de)
NL (1)	NL8700366A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5137724A (en) *	1990-05-23	1992-08-11	Stichting Rega Vzw	Combinations of TS-inhibitors and viral TK-inhibitors in antiherpetic medicines
WO1996023506A1 (de) *	1995-02-01	1996-08-08	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.	Verwendung von 5' substituierten nukleosiden zur hemmung von resistenzbildung bei der zytostatikabehandlung und arzneimittel, enthaltend diese nukleoside
ATE413881T1 (de)	1997-08-08	2008-11-15	Celmed Oncology Usa Inc	Verfahren und zubereitungen um resistenz gegen biologische oder chemische therapien zu überwinden
ES2172303T3 (es)	1998-01-23	2002-09-16	Newbiotics Inc	Agentes terapeuticos obtenidos por catalisis enzimatica.
US7462605B2 (en)	1998-01-23	2008-12-09	Celmed Oncology (Usa), Inc.	Phosphoramidate compounds and methods of use
IL147749A0 (en)	1999-07-22	2002-08-14	Newbiotics Inc	Methods for treating therapy-resistant tumors
EP1251836A2 (de) *	1999-12-23	2002-10-30	NewBiotics, Inc.	Verwendung von bvdu zur hemmung von hyperproliferativem zellwachstum
DE10108851A1 (de) *	2001-02-23	2002-09-12	Resprotect Gmbh	Verwendung von 5'-substituierten Nukleosiden und/oder deren Prodrugs zur resistenzfreien Therapie von Infektionskrankheiten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2016921B (en) *	1978-03-27	1982-08-18	Taiho Pharmaceutical Co Ltd	Anti cancer compositions containing uracil derivatives
IT1170232B (it) *	1983-10-31	1987-06-03	Anna Gioia Stendardi	Composizioni terapeutiche ad attivita' antivirale
DE3667915D1 (de) *	1985-01-30	1990-02-08	Hoffmann La Roche	Pharmazeutische zusammensetzung.

1987
- 1987-02-13 NL NL8700366A patent/NL8700366A/nl not_active Application Discontinuation
1988
- 1988-02-10 JP JP63031681A patent/JP2688057B2/ja not_active Expired - Lifetime
- 1988-02-11 US US07/154,193 patent/US4894365A/en not_active Expired - Fee Related
- 1988-02-12 ES ES88200265T patent/ES2032942T3/es not_active Expired - Lifetime
- 1988-02-12 AT AT88200265T patent/ATE63817T1/de not_active IP Right Cessation
- 1988-02-12 EP EP88200265A patent/EP0283065B1/de not_active Expired - Lifetime
- 1988-02-12 DE DE8888200265T patent/DE3862961D1/de not_active Expired - Fee Related
1989
- 1989-06-29 US US07/373,824 patent/US4988678A/en not_active Expired - Fee Related
1991
- 1991-08-02 GR GR91401120T patent/GR3002431T3/el unknown

Also Published As

Publication number	Publication date
NL8700366A (nl)	1988-09-01
GR3002431T3 (en)	1992-12-30
EP0283065A1 (de)	1988-09-21
US4988678A (en)	1991-01-29
JPS63203619A (ja)	1988-08-23
JP2688057B2 (ja)	1997-12-08
US4894365A (en)	1990-01-16
ES2032942T3 (es)	1996-07-16
EP0283065B1 (de)	1991-05-29
DE3862961D1 (de)	1991-07-04

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Legal Events

Date	Code	Title	Description
1991-12-15	UEP	Publication of translation of european patent specification
1998-11-15	REN	Ceased due to non-payment of the annual fee