ATE65500T1 - Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung. - Google Patents

Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung.

Info

Publication number
ATE65500T1
ATE65500T1 AT88305654T AT88305654T ATE65500T1 AT E65500 T1 ATE65500 T1 AT E65500T1 AT 88305654 T AT88305654 T AT 88305654T AT 88305654 T AT88305654 T AT 88305654T AT E65500 T1 ATE65500 T1 AT E65500T1
Authority
AT
Austria
Prior art keywords
arylthioalkylphenyl
compositions containing
chem
carbonic acids
arylthioalkylphenylcarboxylic
Prior art date
Application number
AT88305654T
Other languages
English (en)
Inventor
Steven E Hall
Philip D Stein
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Application granted granted Critical
Publication of ATE65500T1 publication Critical patent/ATE65500T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT88305654T 1987-06-29 1988-06-20 Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung. ATE65500T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/067,199 US4752616A (en) 1987-06-29 1987-06-29 Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use
EP88305654A EP0297768B1 (de) 1987-06-29 1988-06-20 Arylthioalkylphenylcarbonsäuren, diese enthaltende Zusammensetzungen und deren Verwendung

Publications (1)

Publication Number Publication Date
ATE65500T1 true ATE65500T1 (de) 1991-08-15

Family

ID=22074375

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88305654T ATE65500T1 (de) 1987-06-29 1988-06-20 Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung.

Country Status (7)

Country Link
US (1) US4752616A (de)
EP (1) EP0297768B1 (de)
JP (1) JPS6426548A (de)
AT (1) ATE65500T1 (de)
DE (1) DE3863857D1 (de)
ES (1) ES2029885T3 (de)
GR (1) GR3003015T3 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3724923A1 (de) * 1987-07-28 1989-02-09 Boehringer Mannheim Gmbh Neue schwefelverbindungen, verfahren zu ihrer herstellung sowie arzneimittel
US4931460A (en) * 1987-09-17 1990-06-05 E. R. Squibb & Sons, Inc. Post-ischemic myocardial dysfunction using thromboxane A2 antagonists
US4925873A (en) * 1988-09-01 1990-05-15 E. R. Squibb & Sons, Inc. Method of treating skin injuries using thromboxane A2 receptor antagonists
US5070099A (en) * 1988-10-31 1991-12-03 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
US4959383A (en) * 1988-10-31 1990-09-25 E. R. Squibb & Sons, Inc. Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US4975452A (en) * 1989-06-02 1990-12-04 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US5106991A (en) * 1989-06-02 1992-04-21 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US5177069A (en) * 1989-12-13 1993-01-05 Kissei Pharmaceutical Co., Ltd. Naphthysulfonylalkanoic acid compounds and pharmaceutical compositions thereof
EP0579731A1 (de) * 1991-04-05 1994-01-26 Smithkline Beecham Corporation Disubstituierte naphthalene
US5280034A (en) * 1991-08-23 1994-01-18 E. R. Squibb & Sons, Inc. Bis-heterocyclic prostaglandin analogs
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
US6670398B2 (en) 1997-05-14 2003-12-30 Atherogenics, Inc. Compounds and methods for treating transplant rejection
US6852878B2 (en) * 1998-05-14 2005-02-08 Atherogenics, Inc. Thioketals and thioethers for inhibiting the expression of VCAM-1
CA2292388C (en) 1997-05-14 2004-07-20 Atherogenics, Inc. Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
JP2002511878A (ja) * 1997-07-01 2002-04-16 アセロジエニクス・インコーポレイテツド 抗酸化剤による過増殖状態の治療の増強
EP1385501A2 (de) * 2001-04-11 2004-02-04 Atherogenics, Inc. Probucol-monoesters und ihre verwendung zur erhöhung des hdl-plasmaspiegels und zur verbesserung der hdl-funktionalität
EP2147679B1 (de) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Zusammensetzungen für den Blut-Hirn-Schrankentransport
US20040110803A1 (en) * 2002-09-13 2004-06-10 Hossein Dovlatabadi Methods and compositions for the use of D-malic acid to decrease serum triglyceride, cholesterol and lipoprotein levels
JP4550800B2 (ja) * 2003-01-13 2010-09-22 アセロジエニクス・インコーポレイテツド プロブコールおよびその誘導体のエステルおよびエーテルの製造方法
US20070260087A1 (en) 2004-04-20 2007-11-08 Atherogenics, Inc. Process of Preparing Esters and Ethers of Probucol and Derivatives Thereof
WO2005112914A2 (en) 2004-04-20 2005-12-01 Atherogenics, Inc. Phenolic antioxidants for the treatment of disorders including arthritis, asthma and coronary artery disease
EP2392258B1 (de) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-Informatiksystem
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗
US8252840B2 (en) * 2007-03-26 2012-08-28 Salutria Pharmaceuticals Llc Methods of derivatives of probucol for the treatment of type II diabetes
WO2008118946A1 (en) * 2007-03-27 2008-10-02 Atherogenics, Inc. Methods and compositions using certain phenolic derivatives for the treatment of diabetes
PL3395372T3 (pl) 2009-02-20 2022-07-25 EnhanX Biopharm Inc. Układ do dostarczania leków na bazie glutationu
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US12161632B2 (en) 2014-05-16 2024-12-10 Cumberland Pharmaceuticals Inc. Compositions and methods of treating cardiac fibrosis with ifetroban
AU2015258805B2 (en) 2014-05-16 2018-05-10 Cumberland Pharmaceuticals, Inc. Compositions and methods of treating cardiac fibrosis with ifetroban
AU2016285566A1 (en) 2015-06-30 2017-12-14 Cumberland Pharmaceuticals, Inc. Thromboxane receptor antagonists in AERD/asthma
ES2955158T3 (es) 2016-05-11 2023-11-29 Cumberland Pharmaceuticals Inc Composiciones y métodos de tratamiento de la distrofia muscular con antagonistas del receptor de tromboxano-A2
CN113754570B (zh) * 2020-06-02 2024-10-25 河北圣泰材料股份有限公司 一种2-丙腈磺酰基乙腈的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
US3600437A (en) * 1969-05-28 1971-08-17 Lilly Co Eli Substituted phenylalkanoic acids and derivatives thereof
US3880916A (en) * 1969-09-17 1975-04-29 Ciba Geigy Corp Cycloaliphatic acids
US3825587A (en) * 1970-05-05 1974-07-23 Rorer Inc William H Substituted phenylacetic acid compounds
SE377113B (de) * 1971-05-15 1975-06-23 Ciba Geigy Ag
US3845089A (en) * 1972-07-27 1974-10-29 Zoecon Corp Phenylheptadienoates
US4074057A (en) * 1973-12-12 1978-02-14 Takeda Chemical Co., Ltd. 2-Halopropionic acid and its derivatives
DE2809377A1 (de) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3169761D1 (en) * 1981-01-09 1985-05-09 Fisons Plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
US4780558A (en) * 1985-02-15 1988-10-25 Ciba-Geigy Corporation Sulfone compounds

Also Published As

Publication number Publication date
US4752616A (en) 1988-06-21
GR3003015T3 (en) 1993-02-17
DE3863857D1 (de) 1991-08-29
EP0297768B1 (de) 1991-07-24
ES2029885T3 (es) 1992-10-01
JPS6426548A (en) 1989-01-27
EP0297768A1 (de) 1989-01-04

Similar Documents

Publication Publication Date Title
ATE65500T1 (de) Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung.
DK165003C (da) Chlorsulfat
HUT56379A (en) Process for producing a-norsteroid-3-carboxylic acid derivatives and compositions comprising such compounds
HUT55401A (en) Process for producing platinum(ii) complexes and pharmaceutical compositions comprising such compounds as active ingredient
DK0454651T3 (da) Hidtil ukendte blodpladeaggregeringsinhibitorer
FI874570A0 (fi) Antibakteriska medel -ii.
DE3362504D1 (en) 1-carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use
ATE69448T1 (de) Chinolincarbonsaeure-derivate, diese enthaltende zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von medikamenten.
IT1197841B (it) Derivati pirido-benzotiazinici ad attivita' antibatterica ed a lunga durata di azione
PT87310A (pt) Process for the preparation of thiadiazole guanidines
RU1779248C (ru) Способ получени производных 2-циано-2-арил-1-/1,2,4-триазол-1-ил/этана
TH2417A (th) อนุพันธุ์ไดไฮโดรเบนโซไพแรน

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee