ATE67496T1 - Thiazolidinderivate, verfahren zu deren herstellung und deren anwendung. - Google Patents

Thiazolidinderivate, verfahren zu deren herstellung und deren anwendung.

Info

Publication number: ATE67496T1
Authority: AT; Austria
Prior art keywords: sup; production; application; therapeutic agent; thiazolide
Prior art date: 1985-06-10

Application number

AT86304413T

Other languages

English (en)

Inventor

Kanji Meguro

Takeshi Fujita

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-10

Filing date

1986-06-10

Publication date

1991-10-15

1986-06-10 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1991-10-15 Application granted granted Critical

1991-10-15 Publication of ATE67496T1 publication Critical patent/ATE67496T1/de

Links

239000003814 drug Substances 0.000 abstract 2
229940124597 therapeutic agent Drugs 0.000 abstract 2
241000124008 Mammalia Species 0.000 abstract 1
ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 abstract 1
FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical group C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
201000005577 familial hyperlipidemia Diseases 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Chemical group 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1
150000001467 thiazolidinediones Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT86304413T 1985-06-10 1986-06-10 Thiazolidinderivate, verfahren zu deren herstellung und deren anwendung. ATE67496T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP60126626A JPH06779B2 (ja)	1985-06-10	1985-06-10	チアゾリジオン誘導体およびそれを含んでなる医薬組成物
EP19860304413 EP0208420B1 (de)	1985-06-10	1986-06-10	Thiazolidinderivate, Verfahren zu deren Herstellung und deren Anwendung

Publications (1)

Publication Number	Publication Date
ATE67496T1 true ATE67496T1 (de)	1991-10-15

Family

ID=14939845

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86304413T ATE67496T1 (de)	1985-06-10	1986-06-10	Thiazolidinderivate, verfahren zu deren herstellung und deren anwendung.

Country Status (7)

Country	Link
US (1)	US4775687A (de)
EP (1)	EP0208420B1 (de)
JP (1)	JPH06779B2 (de)
AT (1)	ATE67496T1 (de)
CA (1)	CA1274523A (de)
DE (1)	DE3681517D1 (de)
HU (1)	HU198042B (de)

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US6251928B1 (en) *	1994-03-16	2001-06-26	Eli Lilly And Company	Treatment of alzheimer's disease employing inhibitors of cathepsin D
CZ289317B6 (cs) *	1994-04-11	2002-01-16	Sankyo Company Limited	Heterocyklická sloučenina, farmaceutický prostředek ji obsahující a její pouľití
US5594015A (en) *	1994-06-22	1997-01-14	Regents Of The University Of California	Thiazolidine derivatives for the treatment of psoriasis
US5703096A (en) *	1994-10-07	1997-12-30	Sankyo Company, Limited	Oxime derivatives, their preparation and their therapeutic use
CZ293016B6 (cs) *	1995-06-01	2004-01-14	Sankyo Company Limited	Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem
IT1287626B1 (it) *	1996-02-27	1998-08-06	Sacmi Forni Spa	Forno monostrato per piastrelle
JPH09323930A (ja)	1996-04-04	1997-12-16	Takeda Chem Ind Ltd	悪液質の予防・治療剤
US7235627B2 (en) *	1996-08-30	2007-06-26	Novo Nordisk A/S	Derivatives of GLP-1 analogs
EP1787646A3 (de) *	1997-06-18	2007-10-03	Smithkline Beecham Plc	Neues Behandlungsverfahren
DE69837089T2 (de) *	1997-06-18	2007-06-21	Smithkline Beecham P.L.C., Brentford	Behandlung der diabetes mit thiazolidindion und sulfonylharnstoff
GB9715295D0 (en) *	1997-07-18	1997-09-24	Smithkline Beecham Plc	Novel method of treatment
GB9715306D0 (en) *	1997-07-18	1997-09-24	Smithkline Beecham Plc	Novel method of treatment
KR100666887B1 (ko) *	1997-10-08	2007-01-10	상꾜 가부시키가이샤	치환 축합 복소환 화합물
AR023700A1 (es) *	1998-11-12	2002-09-04	Smithkline Beecham Plc	Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
GB9824893D0 (en) *	1998-11-12	1999-01-06	Smithkline Beckman Corp	Novel method of treatment
CZ20011629A3 (cs)	1998-11-12	2001-12-12	Smithkline Beecham Plc	Farmaceutický prostředek pro upravené uvolňování senzitizéru inzulínu a jiných antidiabetických přípravků
JP2001072592A (ja)	1999-07-01	2001-03-21	Kyowa Hakko Kogyo Co Ltd	テロメラーゼ阻害剤
ES2225252T3 (es) *	1999-11-10	2005-03-16	Takeda Chemical Industries, Ltd.	Compuestos n-heterociclicos de 5 miembros con actividad hipoglucemica e hipolipidemica.
GB0014969D0 (en)	2000-06-19	2000-08-09	Smithkline Beecham Plc	Novel method of treatment
US6452014B1 (en)	2000-12-22	2002-09-17	Geron Corporation	Telomerase inhibitors and methods of their use
JP4152641B2 (ja) *	2001-08-07	2008-09-17	クラシエ製薬株式会社	チアゾリジン誘導体の副作用軽減剤
US8216609B2 (en) *	2002-08-05	2012-07-10	Torrent Pharmaceuticals Limited	Modified release composition of highly soluble drugs
US8268352B2 (en) *	2002-08-05	2012-09-18	Torrent Pharmaceuticals Limited	Modified release composition for highly soluble drugs
US20160331729A9 (en)	2007-04-11	2016-11-17	Omeros Corporation	Compositions and methods for prophylaxis and treatment of addictions
US11241420B2 (en)	2007-04-11	2022-02-08	Omeros Corporation	Compositions and methods for prophylaxis and treatment of addictions
US8426439B2 (en)	2007-04-11	2013-04-23	Omeros Corporation	Compositions and methods for prophylaxis and treatment of addictions
JP6163289B2 (ja)	2009-03-11	2017-07-12	オメロスコーポレーション	嗜癖の予防および治療のための組成物および方法
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US20120094959A1 (en)	2010-10-19	2012-04-19	Bonnie Blazer-Yost	Treatment of cystic diseases
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1985
- 1985-06-10 JP JP60126626A patent/JPH06779B2/ja not_active Expired - Lifetime
1986
- 1986-06-02 US US06/869,704 patent/US4775687A/en not_active Expired - Lifetime
- 1986-06-09 HU HU862431A patent/HU198042B/hu not_active IP Right Cessation
- 1986-06-09 CA CA000511100A patent/CA1274523A/en not_active Expired - Lifetime
- 1986-06-10 EP EP19860304413 patent/EP0208420B1/de not_active Expired - Lifetime
- 1986-06-10 AT AT86304413T patent/ATE67496T1/de not_active IP Right Cessation
- 1986-06-10 DE DE8686304413T patent/DE3681517D1/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPS61286376A (ja)	1986-12-16
EP0208420B1 (de)	1991-09-18
CA1274523A (en)	1990-09-25
JPH06779B2 (ja)	1994-01-05
HUT43599A (en)	1987-11-30
DE3681517D1 (de)	1991-10-24
US4775687A (en)	1988-10-04
EP0208420A1 (de)	1987-01-14
HU198042B (en)	1989-07-28

Legal Events

Date	Code	Title	Description
2003-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3681517D1 (de)	1991-10-24	Thiazolidinderivate, verfahren zu deren herstellung und deren anwendung.
DE3577092D1 (de)	1990-05-17	Thiazolidindionderivate, ihre herstellung und anwendung.
DE3783988D1 (de)	1993-03-18	Zyklische enolderivate, herstellung und anwendung.
MY102016A (en)	1992-02-29	Thiazolidinedione derivatives, their production and use.
ATE68172T1 (de)	1991-10-15	Naphthalenderivate, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen.
NO851934L (no)	1985-11-18	Fremgangsmaate ved fremstilling av terapeutisk aktivt (r)-alfa-ethyl-2-oxo-1-pyrrolidinacetamid.
ATE74352T1 (de)	1992-04-15	Dekahydrochinolinderivate, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
DE3670081D1 (de)	1990-05-10	Imidazolderivate, verfahren zu deren herstellung, deren anwendung und pharmazeutische zusammenstellungen.
ATE2670T1 (de)	1986-03-15	4-phenoxypiperidine, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel.
KR880007457A (ko)	1988-08-27	프롤리날 유도체
ATE53032T1 (de)	1990-06-15	2-thiazolylimidazo(1,2-a)pyrimidine und ihre salze, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und diese enthaltende zubereitungen.
DE69110828D1 (de)	1995-08-03	Heterozyklische Aminderivate, deren Herstellung und deren Verwendung.
ATE67199T1 (de)	1991-09-15	Benzoxazin-derivate und verfahren zu ihrer herstellung.
ATE48276T1 (de)	1989-12-15	1,6-naphthyridin-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel.
SE8501613D0 (sv)	1985-04-01	Foreningar for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutisk behandling
ATE89558T1 (de)	1993-06-15	3(2h)-pyridazinonderivate, verfahren und zwischenprodukte zu deren herstellung und diese und/oder andere 3(2h)-pyridazinonderivate enthaltende heilmittel.
ES2070959T3 (es)	1995-06-16	Utilizacion de derivados del bis(4-hidroxifeniltio)metano en el tratamiento de la diabetes mellitus.
ATE52509T1 (de)	1990-05-15	Thiazolidinderivate und verfahren zu ihrer herstellung.
ATE126432T1 (de)	1995-09-15	Verwendung von bisphenol-derivaten zur behandlung von diabetes mellitus.
KR900004730A (ko)	1990-04-12	정신병 치료제인 4-[4-(3-벤즈이소티아졸릴)-1-피페라지닐]부틸 가교결합된 이환상 이미드
DE3770117D1 (de)	1991-06-20	Neue 1-/ 3-(2-dialkylaminoaethoxy)-2-thienyl/-3-phenyl-1-propanone und ihre saeureadditionssalze und verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ATE144900T1 (de)	1996-11-15	Verwendung von xanthinderivaten gegen magengeschwüre
ATE92074T1 (de)	1993-08-15	Beta-d-phenylthioxyloside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3679257D1 (de)	1991-06-20	4-cyanopiperidine-derivate, herstellung und anwendung.
ATE44741T1 (de)	1989-08-15	2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.