ATE69837T1 - Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse. - Google Patents
Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse.Info
- Publication number
- ATE69837T1 ATE69837T1 AT85304439T AT85304439T ATE69837T1 AT E69837 T1 ATE69837 T1 AT E69837T1 AT 85304439 T AT85304439 T AT 85304439T AT 85304439 T AT85304439 T AT 85304439T AT E69837 T1 ATE69837 T1 AT E69837T1
- Authority
- AT
- Austria
- Prior art keywords
- measuring
- methods
- fluorescence
- introducing
- cell viability
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000003570 cell viability assay Methods 0.000 title 1
- 239000002254 cytotoxic agent Substances 0.000 abstract 2
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 2
- 230000003013 cytotoxicity Effects 0.000 abstract 2
- 231100000135 cytotoxicity Toxicity 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229940041181 antineoplastic drug Drugs 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 abstract 1
- 239000007850 fluorescent dye Substances 0.000 abstract 1
- 230000007154 intracellular accumulation Effects 0.000 abstract 1
- UPSFMJHZUCSEHU-JYGUBCOQSA-N n-[(2s,3r,4r,5s,6r)-2-[(2r,3s,4r,5r,6s)-5-acetamido-4-hydroxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide Chemical compound CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](O)[C@@H](NC(C)=O)[C@H](OC=2C=C3OC(=O)C=C(C)C3=CC=2)O[C@@H]1CO UPSFMJHZUCSEHU-JYGUBCOQSA-N 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 239000002699 waste material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/623,183 US4734372A (en) | 1983-02-04 | 1984-06-21 | Cell culturing methods and apparatus |
| EP85304439A EP0171896B1 (de) | 1984-06-21 | 1985-06-21 | Methoden und Vorrichtung zur Zellentwicklungsfähigkeitsanalyse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE69837T1 true ATE69837T1 (de) | 1991-12-15 |
Family
ID=24497094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85304439T ATE69837T1 (de) | 1984-06-21 | 1985-06-21 | Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4734372A (de) |
| EP (1) | EP0171896B1 (de) |
| JP (1) | JPS6170972A (de) |
| AT (1) | ATE69837T1 (de) |
| DE (1) | DE3584744D1 (de) |
Families Citing this family (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937187A (en) * | 1983-02-04 | 1990-06-26 | Brown University Research Foundation | Methods for separating malignant cells from clinical specimens |
| US4816395A (en) * | 1985-12-19 | 1989-03-28 | Peralta Cancer Research Institute | Method for predicting chemosensitivity of anti-cancer drugs |
| JPS63158459A (ja) * | 1986-09-05 | 1988-07-01 | ライフトレイク | 感受性アツセイの精度を調整する方法 |
| AU8123787A (en) * | 1986-11-17 | 1988-05-19 | Oncotech | Method to monitor and circumvent acquired resistance to chemotherapy in humans |
| US4835102A (en) * | 1987-03-31 | 1989-05-30 | Eugene Bell | Tissue equivalent test systems |
| JPH0782009B2 (ja) * | 1988-03-24 | 1995-09-06 | 工業技術院長 | 細胞融合方法及び装置 |
| JPH0246298A (ja) * | 1988-06-23 | 1990-02-15 | Atomic Energy Canada Ltd | 潜在的毒性の試剤に対する有機体の感性の決定法 |
| US5139946A (en) * | 1988-11-02 | 1992-08-18 | Du Pont Merck Pharmaceutical Company | Dot matrix membrane cell expansion |
| US5068195A (en) * | 1988-11-02 | 1991-11-26 | Du Pont Merck Pharmaceutical Company | Dot matrix membrane cell expansion and maintenance vessel |
| FI83668C (fi) * | 1989-09-08 | 1991-08-12 | Johan Eric Walter Ahlqvist | Foerfarande och medel foer behandling av cytologiska preparat. |
| IL95429A (en) * | 1989-09-15 | 1997-09-30 | Organogenesis | Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production |
| SE464763B (sv) * | 1989-10-05 | 1991-06-10 | Gunnar Engstroem | Metod och anordning foer att studera cellers/cellaggregats reaktionsmoenster vid perfusion med ett testmedium |
| CA2027694C (en) * | 1989-10-20 | 2002-03-05 | Tadashi Matsunaga | Process and apparatus for detecting sensitized leukocyte or antigen |
| US5104804A (en) * | 1990-06-04 | 1992-04-14 | Molecular Devices Corporation | Cell assay device used in a microphysiometer |
| US5240856A (en) * | 1991-10-23 | 1993-08-31 | Cellpro Incorporated | Apparatus for cell separation |
| US5672481A (en) * | 1991-10-23 | 1997-09-30 | Cellpro, Incorporated | Apparatus and method for particle separation in a closed field |
| US5612188A (en) * | 1991-11-25 | 1997-03-18 | Cornell Research Foundation, Inc. | Automated, multicompartmental cell culture system |
| IL106662A (en) * | 1993-08-11 | 1996-10-31 | Yissum Res Dev Co | Install a flow cell to monitor blood or any single cell suspension under flow |
| US5686301A (en) * | 1993-09-02 | 1997-11-11 | Heraeus Instruments Gmbh | Culture vessel for cell cultures |
| US5599688A (en) * | 1993-10-18 | 1997-02-04 | Precision Instrument Design | Device and method for circulating fluid over a membrane |
| US6054287A (en) * | 1994-05-27 | 2000-04-25 | Methodist Hospital Of Indiana, Inc. | Cell-type-specific methods and devices for the low temperature preservation of the cells of an animal species |
| US5595866A (en) * | 1994-05-27 | 1997-01-21 | Methodist Hospital Of Indiana, Inc. | Step-wise method to remove cryoprotectant from sperm |
| US5565353A (en) * | 1994-06-22 | 1996-10-15 | Board Of Regents, The University Of Texas System | Perfusable culture device |
| US6214617B1 (en) | 1995-03-28 | 2001-04-10 | Kinetic Biosystems, Inc. | Centrifugal fermentation process |
| US6660509B1 (en) | 1995-03-28 | 2003-12-09 | Kinetic Biosystems, Inc. | Methods and devices for remediation and fermentation |
| US20050266548A1 (en) * | 1995-03-28 | 2005-12-01 | Kbi Biopharma, Inc. | Biocatalyst chamber encapsulation system for bioremediation and fermentation with improved rotor |
| US6916652B2 (en) * | 1995-03-28 | 2005-07-12 | Kinetic Biosystems, Inc. | Biocatalyst chamber encapsulation system for bioremediation and fermentation |
| US6133019A (en) * | 1995-03-28 | 2000-10-17 | Kinetic Biosystems, Inc. | Centrifugal fermentation process |
| US5622819A (en) * | 1995-03-28 | 1997-04-22 | Kinetic Biosystems, Inc. | Centrifugal fermentation process |
| US5721135A (en) * | 1995-07-06 | 1998-02-24 | Novo Nordisk A/S | Apparatus for identifying biologically active substances by their effect on living cells |
| WO1997017426A1 (en) | 1995-11-08 | 1997-05-15 | Trustees Of Boston University | Cellular physiology workstations for automated data acquisition and perfusion control |
| US5641893A (en) * | 1996-02-22 | 1997-06-24 | University Of Kentucky Research Foundation | Chromatographic separation apparatus |
| NL1007489C2 (nl) * | 1996-11-08 | 2000-10-24 | Konink Grolsch N V | Werkwijze en inrichting voor het in een medium aantonen van micro-organismen. |
| DE19721477A1 (de) * | 1997-05-23 | 1998-11-26 | Abb Patent Gmbh | Mikrobieller Membranreaktor zur Verwendung in Fließsystemen |
| US6197575B1 (en) * | 1998-03-18 | 2001-03-06 | Massachusetts Institute Of Technology | Vascularized perfused microtissue/micro-organ arrays |
| US6673008B1 (en) | 1998-04-28 | 2004-01-06 | Ronald J. Thompson | Fallopian tube and method of in vitro fertilization and embryo development |
| US6908770B1 (en) * | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
| US6146883A (en) * | 1998-09-14 | 2000-11-14 | Navicyte, Inc. | Packing device for transporting confluent cell monolayers |
| DE19932439C2 (de) * | 1999-07-12 | 2002-06-13 | Sefar Ag Rueschlikon | Bioreaktor |
| US6642046B1 (en) * | 1999-12-09 | 2003-11-04 | Motorola, Inc. | Method and apparatus for performing biological reactions on a substrate surface |
| US6703217B2 (en) | 2000-01-31 | 2004-03-09 | Kinetic Biosystems, Inc. | Methods and devices for remediation and fermentation |
| AUPQ653000A0 (en) | 2000-03-28 | 2000-04-20 | Cook Incorporated | Perfusion incubator |
| AU2001249559B2 (en) * | 2000-03-28 | 2004-10-07 | Cook Incorporated | Perfusion incubator |
| US6670170B1 (en) | 2000-05-15 | 2003-12-30 | The United States Of America As Represented By The Secretary Of The Army | Temperature-regulated cell perifusion chamber |
| ATE475887T1 (de) * | 2000-09-09 | 2010-08-15 | Univ New York State Res Found | Verfahren und zusammensetzungen zur isolierung von metastatischen krebszellen und anwendung zur messung des metastatischen potentials eines krebses |
| US20030036049A1 (en) * | 2001-01-03 | 2003-02-20 | Medis El Ltd. | Optical method for testing sensitivity of cells |
| TW581119U (en) * | 2001-12-19 | 2004-03-21 | Univ Nat Cheng Kung | Petri dish for microscope |
| US8257967B2 (en) * | 2002-04-26 | 2012-09-04 | Board Of Regents, The University Of Texas System | Method and system for the detection of cardiac risk factors |
| US7407781B2 (en) * | 2002-05-08 | 2008-08-05 | Wyeth | Oocyte recording chamber |
| US6980293B1 (en) * | 2002-06-11 | 2005-12-27 | Olympus Optical Co., Ltd. | Immersion medium supply apparatus, fluorescence spectrometry inspection apparatus, and culture microscope |
| AU2003256742A1 (en) * | 2002-07-24 | 2004-02-09 | Board Of Regents, The University Of Texas System | Capture and detection of microbes by membrane methods |
| GB2433319A (en) * | 2002-10-23 | 2007-06-20 | Yissum Res Dev Co | In vitro test for studying compound predicting pharmacologic and/or pharmacokinetic and/or pharmacodynamic parameters of a compound |
| US7245368B2 (en) * | 2003-03-31 | 2007-07-17 | C & L Instruments | Sample chamber for microscopy |
| US9317922B2 (en) | 2003-05-16 | 2016-04-19 | Board Of Regents The University Of Texas System | Image and part recognition technology |
| US7651850B2 (en) | 2003-05-16 | 2010-01-26 | Board Of Regents, The University Of Texas System | Image and part recognition technology |
| EP1695082A2 (de) * | 2003-12-11 | 2006-08-30 | Board of Regents, The University of Texas System | Verfahren und vorrichtung für die analyse von speichel unter verwendung eines sensorarrays |
| US20070037276A1 (en) * | 2004-02-23 | 2007-02-15 | Eudes Francois Marie De Crecy | Continuous culture apparatus with mobile vessel, allowing selection of fitter cell variants and producing a culture in a continuous manner |
| US8105849B2 (en) * | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
| US8101431B2 (en) * | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
| EP1739164B1 (de) * | 2004-04-13 | 2016-08-10 | Toyo Seikan Group Holdings, Ltd. | Doppelinkubator und inkubationsverfahren |
| DK1773978T3 (da) * | 2004-05-19 | 2014-05-26 | Univ Pittsburgh | Perfunderede, tredimensionelle celle/vævssygdomsmodeller |
| JP2006025789A (ja) * | 2004-06-17 | 2006-02-02 | Olympus Corp | 生体試料観察システムおよび生体試料の観察方法 |
| US20060095021A1 (en) * | 2004-11-02 | 2006-05-04 | Casas-Bejar Jesus W | Introduction of agent with medical device |
| US8377398B2 (en) | 2005-05-31 | 2013-02-19 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to determination and use of white blood cell counts |
| WO2006137768A1 (en) * | 2005-06-23 | 2006-12-28 | Gambro Lundia Ab | Implantable access device and method for preparing thereof |
| EP2508867A1 (de) * | 2005-06-24 | 2012-10-10 | Board Of Regents, The University Of Texas System | Systeme und Verfahren einschliesslich in sich geschlossener Kassetten mit Nachweissystemen und Flüssigkeitszufuhrsystemen |
| US20090215646A1 (en) * | 2005-07-01 | 2009-08-27 | The Board Of Regents Of The University Of Texas Sy | System and method of analyte detection using differential receptors |
| DE102005051406A1 (de) * | 2005-10-27 | 2007-05-03 | Forschungszentrum Rossendorf E.V. | Optisches Koppelelement für eine Durchflusszelle |
| FR2897783B1 (fr) * | 2006-02-24 | 2008-05-30 | Millipore Corp | Dispositif pour le controle microbiologique, ensembles de controle et d'incubation le comportant et procede le mettant en oeuvre |
| FR2901806B1 (fr) * | 2006-06-01 | 2008-08-01 | Millipore Corp | Dispositif et ensemble de controle microbiologique |
| US20100151571A1 (en) * | 2006-07-07 | 2010-06-17 | Georgia Tech Research Corporation | Centimeter-scale, integrated diagnostics incubator for biological culturing |
| WO2008131039A2 (en) * | 2007-04-16 | 2008-10-30 | Board Of Regents, The University Of Texas System | Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics |
| CN107988072B (zh) | 2008-07-16 | 2022-11-29 | 儿童医疗中心有限公司 | 具有微通道的器官模仿装置及其使用和制造方法 |
| EP2158967A1 (de) * | 2008-08-26 | 2010-03-03 | F. Hoffmann-La Roche AG | Probenträger |
| WO2010080643A1 (en) * | 2008-12-18 | 2010-07-15 | Biovigilant Systems, Inc. | Integrated microbial collector |
| US20100279354A1 (en) * | 2009-04-29 | 2010-11-04 | Evolugate, Llc | Adapting microorganisms for agricultural products |
| US9574166B2 (en) | 2010-08-18 | 2017-02-21 | Drugmode Aps | Bioreactor system |
| CN103261395B (zh) | 2010-12-15 | 2017-09-08 | 药物模式有限责任公司 | 具有便于进入培养腔的盖子的生物反应器 |
| RU2612915C2 (ru) | 2011-02-28 | 2017-03-13 | Президент Энд Феллоуз Ов Харвард Колледж | Система культивирования клеток |
| WO2013086486A1 (en) | 2011-12-09 | 2013-06-13 | President And Fellows Of Harvard College | Integrated human organ-on-chip microphysiological systems |
| JP5989483B2 (ja) * | 2012-09-24 | 2016-09-07 | テルモ株式会社 | 膜状組織の保存輸送容器および保存輸送方法 |
| US9855554B2 (en) | 2013-07-22 | 2018-01-02 | President And Fellows Of Harvard College | Microfluidic cartridge assembly |
| AU2014386209B2 (en) | 2013-12-20 | 2021-03-11 | President And Fellows Of Harvard College | Low shear microfluidic devices and methods of use and manufacturing thereof |
| GB2581749B (en) | 2013-12-20 | 2021-03-03 | Harvard College | Organomimetic devices and methods of use and manufacturing thereof |
| WO2016010861A1 (en) | 2014-07-14 | 2016-01-21 | President And Fellows Of Harvard College | Systems and methods for improved performance of fluidic and microfluidic systems |
| WO2017019542A1 (en) | 2015-07-24 | 2017-02-02 | President And Fellows Of Harvard College | Radial microfluidic devices and methods of use |
| JP7002040B2 (ja) | 2015-10-02 | 2022-02-04 | ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ | がん転移をモデル化するためのｉｎ ｖｉｔｒｏでの方法および装置 |
| CA3036378A1 (en) | 2016-09-13 | 2018-03-22 | President And Fellows Of Harvard College | Methods relating to intestinal organ-on-a-chip |
| EP3746785A4 (de) | 2018-02-02 | 2022-05-11 | Wake Forest University Health Sciences, Inc. | Mit einer immuntherapie verwandte organoide und verfahren zur herstellung und verwendung davon |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2942520A (en) * | 1955-12-20 | 1960-06-28 | George G Rose | Tissue culture device |
| US3065148A (en) * | 1959-07-14 | 1962-11-20 | Technicon Instr | Method and apparatus for use in conducting studies on cells |
| US3691017A (en) * | 1970-05-06 | 1972-09-12 | Worthington Bio Chem Corp | Means and method for chemical analysis |
| US3726597A (en) * | 1972-03-09 | 1973-04-10 | Us Health Education & Welfare | Controlled environment culture system for light microscopy |
| US3883393A (en) * | 1972-05-18 | 1975-05-13 | Us Health Education & Welfare | Cell culture on semi-permeable tubular membranes |
| US3821087A (en) * | 1972-05-18 | 1974-06-28 | Dedrick R | Cell culture on semi-permeable tubular membranes |
| DE2319204B2 (de) * | 1973-04-16 | 1977-04-07 | CA. Greiner und Söhne, 7440 Nürtingen | Arbeitsgeraet fuer histologische untersuchungen |
| US3928142A (en) * | 1973-07-24 | 1975-12-23 | Dennis B Smith | Culture chamber for the study of biological systems and method of fabrication thereof |
| US4201845A (en) * | 1976-04-12 | 1980-05-06 | Monsanto Company | Cell culture reactor |
| US4184922A (en) * | 1977-11-11 | 1980-01-22 | The Government Of The United States | Dual circuit, woven artificial capillary bundle for cell culture |
| US4220725A (en) * | 1978-04-03 | 1980-09-02 | United States Of America | Capillary cell culture device |
| US4242459A (en) * | 1978-11-02 | 1980-12-30 | Chick William L | Cell culture device |
| US4241187A (en) * | 1979-03-27 | 1980-12-23 | United States Of America | Method and apparatus for cell and tissue culture |
| JPS5642584A (en) * | 1979-09-18 | 1981-04-20 | Asahi Chem Ind Co Ltd | Cell cultivation method |
| SU901266A1 (ru) * | 1979-12-20 | 1982-01-30 | Предприятие П/Я А-1631 | Камера дл культивировани микроорганизмов |
| US4308351A (en) * | 1980-04-18 | 1981-12-29 | Joseph Leighton | System for growing tissue cultures |
| US4440853A (en) * | 1980-08-21 | 1984-04-03 | Board Of Trustees Of The Leland Stanford Junior University | Microbiological methods using hollow fiber membrane reactor |
| US4537860A (en) * | 1982-12-08 | 1985-08-27 | Monsanto Company | Static cell culture maintenance system |
| US4559299A (en) * | 1983-02-04 | 1985-12-17 | Brown University Research Foundation Inc. | Cytotoxicity assays in cell culturing devices |
-
1984
- 1984-06-21 US US06/623,183 patent/US4734372A/en not_active Expired - Fee Related
-
1985
- 1985-06-21 DE DE8585304439T patent/DE3584744D1/de not_active Expired - Fee Related
- 1985-06-21 AT AT85304439T patent/ATE69837T1/de not_active IP Right Cessation
- 1985-06-21 EP EP85304439A patent/EP0171896B1/de not_active Expired - Lifetime
- 1985-06-21 JP JP60134451A patent/JPS6170972A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0171896B1 (de) | 1991-11-27 |
| JPH0574358B2 (de) | 1993-10-18 |
| EP0171896A1 (de) | 1986-02-19 |
| US4734372A (en) | 1988-03-29 |
| DE3584744D1 (de) | 1992-01-09 |
| JPS6170972A (ja) | 1986-04-11 |
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