ATE70186T1 - Thyrotropin abgebende hormonanaloge fuer verletzungen am zentralnervensystem. - Google Patents

Thyrotropin abgebende hormonanaloge fuer verletzungen am zentralnervensystem.

Info

Publication number: ATE70186T1
Authority: AT; Austria
Prior art keywords: thyrotropin; nervous system; central nervous; prolineamide; histidyl
Prior art date: 1987-06-05

Application number

AT88906641T

Other languages

English (en)

Inventor

Alan I Faden

Original Assignee

Medicis Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-05

Filing date

1988-06-06

Publication date

1991-12-15

1988-06-06 Application filed by Medicis Corp filed Critical Medicis Corp

1991-12-15 Application granted granted Critical

1991-12-15 Publication of ATE70186T1 publication Critical patent/ATE70186T1/de

Links

208000001738 Nervous System Trauma Diseases 0.000 title abstract 3
210000003169 central nervous system Anatomy 0.000 title abstract 3
230000003054 hormonal effect Effects 0.000 title 1
230000000302 ischemic effect Effects 0.000 abstract 2
208000028412 nervous system injury Diseases 0.000 abstract 2
XNSAINXGIQZQOO-SRVKXCTJSA-N protirelin Chemical class NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-SRVKXCTJSA-N 0.000 abstract 2
239000003045 protirelin derivative Substances 0.000 abstract 2
230000000472 traumatic effect Effects 0.000 abstract 2
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
VLJNHYLEOZPXFW-BYPYZUCNSA-N L-prolinamide Chemical group NC(=O)[C@@H]1CCCN1 VLJNHYLEOZPXFW-BYPYZUCNSA-N 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
239000011737 fluorine Substances 0.000 abstract 1
125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 abstract 1
229910052740 iodine Chemical group 0.000 abstract 1
239000011630 iodine Chemical group 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
238000004321 preservation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT88906641T 1987-06-05 1988-06-06 Thyrotropin abgebende hormonanaloge fuer verletzungen am zentralnervensystem. ATE70186T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US5833987A	1987-06-05	1987-06-05
PCT/US1988/001837 WO1988009604A2 (en)	1987-06-05	1988-06-06	Thyrotropin-releasing hormone analogs in cns injury
EP88906641A EP0317624B1 (de)	1987-06-05	1988-06-06	Thyrotropin abgebende hormonanaloge für verletzungen am zentralnervensystem

Publications (1)

Publication Number	Publication Date
ATE70186T1 true ATE70186T1 (de)	1991-12-15

Family

ID=22016211

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88906641T ATE70186T1 (de)	1987-06-05	1988-06-06	Thyrotropin abgebende hormonanaloge fuer verletzungen am zentralnervensystem.

Country Status (6)

Country	Link
EP (1)	EP0317624B1 (de)
JP (1)	JPH01503542A (de)
AT (1)	ATE70186T1 (de)
CA (1)	CA1323301C (de)
DE (1)	DE3866860D1 (de)
WO (1)	WO1988009604A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE20000240A1 (en)	2000-02-17	2003-03-05	Trinity College Dublin	TRH-like peptide derivatives
DE10105040A1 (de)	2001-02-05	2002-08-14	Tell Pharm Ag Hergiswil	Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
DE10105041A1 (de)	2001-02-05	2002-08-14	Tell Pharm Ag Hergiswil	Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten
DE10105038B4 (de)	2001-02-05	2005-07-07	Neurotell Ag	Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
GB0128405D0 (en)	2001-11-27	2002-01-16	Btg Int Ltd	Process for fabricating polyolefin sheet

1988
- 1988-06-03 CA CA000568686A patent/CA1323301C/en not_active Expired - Fee Related
- 1988-06-06 DE DE8888906641T patent/DE3866860D1/de not_active Expired - Lifetime
- 1988-06-06 JP JP63506706A patent/JPH01503542A/ja active Pending
- 1988-06-06 WO PCT/US1988/001837 patent/WO1988009604A2/en not_active Ceased
- 1988-06-06 EP EP88906641A patent/EP0317624B1/de not_active Expired - Lifetime
- 1988-06-06 AT AT88906641T patent/ATE70186T1/de active

Also Published As

Publication number	Publication date
JPH01503542A (ja)	1989-11-30
EP0317624B1 (de)	1991-12-11
WO1988009604A2 (en)	1988-12-15
CA1323301C (en)	1993-10-19
EP0317624A1 (de)	1989-05-31
DE3866860D1 (de)	1992-01-23

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