ATE71113T1 - Antibiotikum a 40926 mannosyl aglycon. - Google Patents

Antibiotikum a 40926 mannosyl aglycon.

Info

Publication number: ATE71113T1
Authority: AT; Austria
Prior art keywords: antibiotic; mannosyl; mannosyl aglycone; aglycone; preparing
Prior art date: 1985-12-30

Application number

AT86117453T

Other languages

English (en)

Inventor

Enrico Selva

Peetro Ferrari

Beth P Goldstein

Giovanni Cassani

Francesco Parenti

Original Assignee

Lepetit Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-30

Filing date

1986-12-15

Publication date

1992-01-15

1986-12-15 Application filed by Lepetit Spa filed Critical Lepetit Spa

1992-01-15 Application granted granted Critical

1992-01-15 Publication of ATE71113T1 publication Critical patent/ATE71113T1/de

Links

BEVDFPMXVNOQBI-AXNWEOKVSA-N (19R,22R,34S,37R,40R,52S)-64-[(2S,3R,4R,5S,6S)-3-amino-6-carboxy-4,5-dihydroxyoxan-2-yl]oxy-5,32-dichloro-2,26,31,49-tetrahydroxy-22-(methylamino)-21,35,38,54,56,59-hexaoxo-47-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51]hexahexaconta-3,5,8,10,12(64),14(63),15,17(62),23(61),24,26,29(60),30,32,41,43,45(57),46(51),47,49,65-henicosaene-52-carboxylic acid Chemical compound CN[C@@H]1c2ccc(O)c(Oc3cc(O)c(Cl)c(c3)[C@@H]3NC(=O)[C@@H](Cc4ccc(Oc5cc6cc(Oc7ccc(cc7Cl)C(O)C7NC(=O)[C@H](NC(=O)[C@@H]6NC3=O)c3cccc(c3)-c3c(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)cc(O)cc3[C@H](NC7=O)C(O)=O)c5O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3N)C(O)=O)cc4)NC1=O)c2 BEVDFPMXVNOQBI-AXNWEOKVSA-N 0.000 title abstract 3
TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 title 1
PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 title 1
PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 title 1
208000035473 Communicable disease Diseases 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
125000000311 mannosyl group Chemical group C1([C@@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Compounds Of Unknown Constitution (AREA)

AT86117453T 1985-12-30 1986-12-15 Antibiotikum a 40926 mannosyl aglycon. ATE71113T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858531846A GB8531846D0 (en)	1985-12-30	1985-12-30	Antibiotic a 40926 mannosyl aglycon
EP86117453A EP0228015B1 (de)	1985-12-30	1986-12-15	Antibiotikum A 40926 Mannosyl Aglycon

Publications (1)

Publication Number	Publication Date
ATE71113T1 true ATE71113T1 (de)	1992-01-15

Family

ID=10590309

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86117453T ATE71113T1 (de)	1985-12-30	1986-12-15	Antibiotikum a 40926 mannosyl aglycon.

Country Status (14)

Country	Link
US (1)	US4782042A (de)
EP (1)	EP0228015B1 (de)
JP (1)	JP2514942B2 (de)
KR (2)	KR950010460B1 (de)
AT (1)	ATE71113T1 (de)
DE (1)	DE3683266D1 (de)
DK (1)	DK167815B1 (de)
ES (1)	ES2038593T3 (de)
GB (1)	GB8531846D0 (de)
GR (1)	GR3003514T3 (de)
HU (1)	HU201099B (de)
IE (1)	IE59603B1 (de)
IL (1)	IL81105A (de)
ZA (1)	ZA869716B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK363587A (da) *	1986-07-30	1988-01-31	Smithkline Beckman Corp	Antibiotika og fremstilling heraf under anvendelseaf actinomadura parvosata
GB8621912D0 (en) *	1986-09-11	1986-10-15	Lepetit Spa	Increasing ratio of components of anti-biotic complex
GR871488B (en) *	1986-10-10	1987-11-12	Lepetit Spa	New antibiotics
ATE135369T1 (de) *	1988-12-27	1996-03-15	Lepetit Spa	Chemisches verfahren zur herstellung des antibiotikums l 17392 (deglukoteicoplanin) und dessen salze
US5206834A (en) *	1989-10-14	1993-04-27	Mitsubishi Denki Kabushiki Kaisha	Semiconductor memory device performing last in-first out operation and the method for controlling the same
CA2027629C (en) *	1989-10-16	2000-01-25	Karl H. Michel	Glycopeptide antibiotics
US5224972A (en) *	1990-09-11	1993-07-06	Frye Gregory C	Coatings with controlled porosity and chemical properties
WO1992010516A1 (en) *	1990-12-05	1992-06-25	Gruppo Lepetit S.P.A.	38-decarboxy-38-hydroxymethyl derivatives of teicoplanin antibiotics, and a process for preparing them
DE69215665T2 (de)	1991-03-27	1997-06-12	Gruppo Lepetit S.P.A., Lainate	Esterderivate von antibiotikum-a 40926
US5606036A (en) *	1991-03-27	1997-02-25	Gruppo Lepetit Spa	Antibiotic A 40926 ester derivatives
US5750509A (en) *	1991-07-29	1998-05-12	Gruppo Lepetit S.P.A.	Amide derivatives of antibiotic A 40926
CN1036654C (zh) *	1993-01-01	1997-12-10	格鲁波莱佩蒂特公司	抗菌素a40926的酰氨衍生物及其制备方法
PT836619E (pt) *	1995-07-05	2004-11-30	Aventis Bulk S P A	Purificacao de antibioticos dalba-heptidicos por focagem isoelectrica
EP0912604B1 (de)	1996-04-23	2001-11-14	Biosearch Italia S.p.A.	Chemisches Verfahren zur Herstellung von Amidderivaten von A 40926 Antibiotikum
US20060074014A1 (en)	2002-11-18	2006-04-06	Vicuron Pharmaceuticals Inc.	Dalbavancin compositions for treatment of bacterial infections
US7119061B2 (en) *	2002-11-18	2006-10-10	Vicuron Pharmaceuticals, Inc.	Dalbavancin compositions for treatment of bacterial infections
MXPA05005338A (es) *	2002-11-18	2005-12-14	Vicuron Pharm Inc	Metodos para administrar dalbavancin para el tratamiento de infecciones bacterianas.
JP5852880B2 (ja) *	2011-12-28	2016-02-03	国立研究開発法人国立循環器病研究センター	温度感応性材料
WO2020222100A1 (en) *	2019-04-30	2020-11-05	Actygea S.R.L.	Method for the purification of lipoglycopeptide antibiotics
KR102467772B1 (ko)	2022-08-23	2022-11-16	최세근	디자인에 따라 결합 가능한 모듈이 구비된 신발

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4521335A (en) *	1983-07-13	1985-06-04	Smithkline Beckman Corporation	Aglycone and pseudo-aglycones of the AAD 216 antibiotics
GB8425685D0 (en) *	1984-10-11	1984-11-14	Lepetit Spa	Antibiotic a 40926 complex

1985
- 1985-12-30 GB GB858531846A patent/GB8531846D0/en active Pending
1986
- 1986-12-15 EP EP86117453A patent/EP0228015B1/de not_active Expired - Lifetime
- 1986-12-15 DE DE8686117453T patent/DE3683266D1/de not_active Expired - Lifetime
- 1986-12-15 ES ES198686117453T patent/ES2038593T3/es not_active Expired - Lifetime
- 1986-12-15 AT AT86117453T patent/ATE71113T1/de not_active IP Right Cessation
- 1986-12-19 DK DK617086A patent/DK167815B1/da not_active IP Right Cessation
- 1986-12-23 IE IE338186A patent/IE59603B1/en not_active IP Right Cessation
- 1986-12-23 US US06/945,732 patent/US4782042A/en not_active Expired - Fee Related
- 1986-12-26 IL IL81105A patent/IL81105A/xx not_active IP Right Cessation
- 1986-12-29 HU HU865503A patent/HU201099B/hu not_active IP Right Cessation
- 1986-12-29 JP JP61315964A patent/JP2514942B2/ja not_active Expired - Lifetime
- 1986-12-29 ZA ZA869716A patent/ZA869716B/xx unknown
- 1986-12-29 KR KR1019860011487A patent/KR950010460B1/ko not_active Expired - Fee Related
1987
- 1987-07-01 KR KR1019870006803A patent/KR960010556B1/ko not_active Expired - Fee Related
1992
- 1992-01-03 GR GR910402184T patent/GR3003514T3/el unknown

Also Published As

Publication number	Publication date
IL81105A0 (en)	1987-03-31
DK167815B1 (da)	1993-12-20
IL81105A (en)	1991-09-16
HU201099B (en)	1990-09-28
EP0228015B1 (de)	1992-01-02
KR870006193A (ko)	1987-07-09
DE3683266D1 (de)	1992-02-13
GR3003514T3 (de)	1993-03-16
DK617086A (da)	1987-07-01
JPS62175499A (ja)	1987-08-01
EP0228015A2 (de)	1987-07-08
KR960010556B1 (ko)	1996-08-02
HUT43091A (en)	1987-09-28
IE863381L (en)	1987-06-30
KR950010460B1 (ko)	1995-09-18
ZA869716B (en)	1987-10-28
GB8531846D0 (en)	1986-02-05
JP2514942B2 (ja)	1996-07-10
KR890002230A (ko)	1989-04-08
US4782042A (en)	1988-11-01
IE59603B1 (en)	1994-03-09
EP0228015A3 (en)	1987-12-16
ES2038593T3 (es)	1993-08-01
DK617086D0 (da)	1986-12-19

Legal Events

Date	Code	Title	Description
1992-09-15	UEP	Publication of translation of european patent specification
1998-09-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE71113T1 (de)	1992-01-15	Antibiotikum a 40926 mannosyl aglycon.
UA27105A1 (uk)	2000-02-28	О-метильhі похідhі азитроміциhу а, що мають аhтибактеріальhу активhість, спосіб їх отримаhhя та проміжhі сполуки
MY101178A (en)	1991-07-31	Antibiotic a 40926 n-acylaminoglucuronyl aglycons and antibiotic a 40926 aglycon
DK312688A (da)	1988-06-09	Glykkopeptid-antibiotika
DK0406745T3 (da)	1995-02-27	Antibiotiske GE 2270 faktorer A1, A2, A3 og H
DK0451486T3 (da)	1995-05-08	Antibiotikum GE 2270 faktorer B1, B2, C1, C2, D1, D2, E og T
ES2037838T3 (es)	1993-07-01	Derivados de eritromicina a modificados en c-12.
DE3872916D1 (de)	1992-08-27	Herstellung und reinigung eines n,n-diethylaminophenols.
DK144284A (da)	1984-09-15	2'-desoxyoxanosin, den fremstilling og anvendelse