ATE72429T1 - Phenoxyessigsaeure-derivate und verfahren zu deren herstellung. - Google Patents
Phenoxyessigsaeure-derivate und verfahren zu deren herstellung.Info
- Publication number
- ATE72429T1 ATE72429T1 AT87114877T AT87114877T ATE72429T1 AT E72429 T1 ATE72429 T1 AT E72429T1 AT 87114877 T AT87114877 T AT 87114877T AT 87114877 T AT87114877 T AT 87114877T AT E72429 T1 ATE72429 T1 AT E72429T1
- Authority
- AT
- Austria
- Prior art keywords
- phenoxyacetic acid
- production
- acid derivatives
- group
- salt
- Prior art date
Links
- LCPDWSOZIOUXRV-UHFFFAOYSA-N phenoxyacetic acid Chemical class OC(=O)COC1=CC=CC=C1 LCPDWSOZIOUXRV-UHFFFAOYSA-N 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 5-pyrazolyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000000894 saliuretic effect Effects 0.000 abstract 1
- 230000003424 uricosuric effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24280286 | 1986-10-13 | ||
| EP87114877A EP0268800B1 (de) | 1986-10-13 | 1987-10-12 | Phenoxyessigsäure-Derivate und Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE72429T1 true ATE72429T1 (de) | 1992-02-15 |
Family
ID=17094503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87114877T ATE72429T1 (de) | 1986-10-13 | 1987-10-12 | Phenoxyessigsaeure-derivate und verfahren zu deren herstellung. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4853404A (de) |
| EP (1) | EP0268800B1 (de) |
| JP (1) | JPS63225359A (de) |
| KR (1) | KR920002296B1 (de) |
| CN (1) | CN1014787B (de) |
| AT (1) | ATE72429T1 (de) |
| AU (1) | AU595385B2 (de) |
| CA (1) | CA1311483C (de) |
| DE (1) | DE3776627D1 (de) |
| DK (1) | DK166879B1 (de) |
| ES (1) | ES2032284T3 (de) |
| FI (1) | FI91402C (de) |
| GR (1) | GR3003727T3 (de) |
| HK (1) | HK47193A (de) |
| HU (1) | HU202501B (de) |
| IE (1) | IE60044B1 (de) |
| IL (1) | IL84106A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2613720B1 (fr) * | 1987-04-10 | 1990-01-19 | Esteve Labor Dr | Derives d'aryl-heteroaryl carbinols avec activite analgesique |
| JPH01316317A (ja) * | 1988-03-10 | 1989-12-21 | Tanabe Seiyaku Co Ltd | 降圧剤 |
| US4956379A (en) * | 1990-02-13 | 1990-09-11 | Bristol-Myers Squibb Company | Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith |
| CA2036192A1 (en) | 1990-02-13 | 1991-08-14 | Nicholas Meanwell | Heterocyclic carboxylic acids and esters |
| US20040067531A1 (en) * | 1997-08-20 | 2004-04-08 | Sugen, Inc. | Methods of modulating protein tyrosine kinase function with substituted indolinone compounds |
| DE122008000002I1 (de) * | 2000-02-15 | 2008-04-17 | Sugen Inc | Pyrrol substituierte indolin-2-on protein kinase inhibitoren |
| AR042586A1 (es) * | 2001-02-15 | 2005-06-29 | Sugen Inc | 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa |
| EP1434774A1 (de) | 2001-10-10 | 2004-07-07 | Sugen, Inc. | 3-(4-substituierte heterocyclyl)-pyrrol-2-ylmethylidene)-2-indolinone derivate als protein-kinase-inhibitoren |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3342851A (en) * | 1964-10-30 | 1967-09-19 | Merck & Co Inc | Esters of [(2-methyleneacyl)phenoxy]-carboxylic acids and a method for their preparation |
| CH543472A (fr) * | 1969-01-31 | 1973-10-31 | Orchimed Sa | Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques |
| GB1415295A (en) * | 1971-10-14 | 1975-11-26 | Orchimed Sa | Substituted phenoxy-alkyl-carboxylic acids and derivatives thereof |
| US4107179A (en) * | 1977-08-22 | 1978-08-15 | Smithkline Corporation | Method for preparing ticrynafen |
| GB2024209B (en) * | 1978-05-31 | 1982-09-08 | Sori Soc Rech Ind | Phenoxalkylcarboxylic acids |
| US4323691A (en) * | 1979-10-09 | 1982-04-06 | Abbott Laboratories | Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters |
-
1987
- 1987-10-05 US US07/105,173 patent/US4853404A/en not_active Expired - Fee Related
- 1987-10-06 IE IE266887A patent/IE60044B1/en not_active IP Right Cessation
- 1987-10-06 IL IL84106A patent/IL84106A/xx not_active IP Right Cessation
- 1987-10-09 JP JP62255347A patent/JPS63225359A/ja active Granted
- 1987-10-10 CN CN87106895A patent/CN1014787B/zh not_active Expired
- 1987-10-12 DE DE8787114877T patent/DE3776627D1/de not_active Expired - Lifetime
- 1987-10-12 FI FI874473A patent/FI91402C/fi not_active IP Right Cessation
- 1987-10-12 DK DK532987A patent/DK166879B1/da active
- 1987-10-12 AU AU79563/87A patent/AU595385B2/en not_active Ceased
- 1987-10-12 HU HU874600A patent/HU202501B/hu not_active IP Right Cessation
- 1987-10-12 ES ES198787114877T patent/ES2032284T3/es not_active Expired - Lifetime
- 1987-10-12 KR KR1019870011259A patent/KR920002296B1/ko not_active Expired
- 1987-10-12 AT AT87114877T patent/ATE72429T1/de not_active IP Right Cessation
- 1987-10-12 EP EP87114877A patent/EP0268800B1/de not_active Expired - Lifetime
- 1987-10-13 CA CA000549137A patent/CA1311483C/en not_active Expired - Lifetime
-
1992
- 1992-02-06 GR GR910401089T patent/GR3003727T3/el unknown
-
1993
- 1993-05-13 HK HK471/93A patent/HK47193A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1014787B (zh) | 1991-11-20 |
| IE60044B1 (en) | 1994-05-18 |
| AU595385B2 (en) | 1990-03-29 |
| EP0268800B1 (de) | 1992-02-05 |
| KR880005089A (ko) | 1988-06-28 |
| FI91402B (fi) | 1994-03-15 |
| US4853404A (en) | 1989-08-01 |
| CA1311483C (en) | 1992-12-15 |
| DE3776627D1 (de) | 1992-03-19 |
| HUT50788A (en) | 1990-03-28 |
| IE872668L (en) | 1988-04-13 |
| FI91402C (fi) | 1994-06-27 |
| JPS63225359A (ja) | 1988-09-20 |
| FI874473L (fi) | 1988-04-14 |
| HU202501B (en) | 1991-03-28 |
| DK532987D0 (da) | 1987-10-12 |
| IL84106A (en) | 1991-07-18 |
| CN87106895A (zh) | 1988-04-20 |
| DK532987A (da) | 1988-04-14 |
| HK47193A (en) | 1993-05-21 |
| DK166879B1 (da) | 1993-07-26 |
| FI874473A0 (fi) | 1987-10-12 |
| AU7956387A (en) | 1988-04-14 |
| GR3003727T3 (de) | 1993-03-16 |
| IL84106A0 (en) | 1988-03-31 |
| JPH0544944B2 (de) | 1993-07-07 |
| ES2032284T3 (es) | 1993-02-01 |
| KR920002296B1 (ko) | 1992-03-21 |
| EP0268800A1 (de) | 1988-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |