IL84106A - (4-(5-pyrazolylcarbonyl-(vinyl)phenoxy))acetic acid and esters,their preparation and pharmaceutical compositions containing them - Google Patents

(4-(5-pyrazolylcarbonyl-(vinyl)phenoxy))acetic acid and esters,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL84106A
Authority: IL; Israel
Prior art keywords: pyrazolylcarbonyl; phenoxy; esters; vinyl; preparation
Prior art date: 1986-10-13

Application number

IL84106A

Other languages

English (en)

Other versions

IL84106A0 (en

Original Assignee

Tanabe Seiyaku Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-10-13

Filing date

1987-10-06

Publication date

1991-07-18

1987-10-06 Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co

1988-03-31 Publication of IL84106A0 publication Critical patent/IL84106A0/xx

1991-07-18 Publication of IL84106A publication Critical patent/IL84106A/xx

Links

QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 title 3
150000002148 esters Chemical class 0.000 title 1
235000019439 ethyl acetate Nutrition 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
-1 5-pyrazolyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
239000002934 diuretic Substances 0.000 abstract 1
230000001882 diuretic effect Effects 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
LCPDWSOZIOUXRV-UHFFFAOYSA-N phenoxyacetic acid Chemical class OC(=O)COC1=CC=CC=C1 LCPDWSOZIOUXRV-UHFFFAOYSA-N 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
230000000894 saliuretic effect Effects 0.000 abstract 1
230000003424 uricosuric effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL84106A 1986-10-13 1987-10-06 (4-(5-pyrazolylcarbonyl-(vinyl)phenoxy))acetic acid and esters,their preparation and pharmaceutical compositions containing them IL84106A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP24280286		1986-10-13

Publications (2)

Publication Number	Publication Date
IL84106A0 IL84106A0 (en)	1988-03-31
IL84106A true IL84106A (en)	1991-07-18

Family

ID=17094503

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL84106A IL84106A (en)	1986-10-13	1987-10-06	(4-(5-pyrazolylcarbonyl-(vinyl)phenoxy))acetic acid and esters,their preparation and pharmaceutical compositions containing them

Country Status (17)

Country	Link
US (1)	US4853404A (de)
EP (1)	EP0268800B1 (de)
JP (1)	JPS63225359A (de)
KR (1)	KR920002296B1 (de)
CN (1)	CN1014787B (de)
AT (1)	ATE72429T1 (de)
AU (1)	AU595385B2 (de)
CA (1)	CA1311483C (de)
DE (1)	DE3776627D1 (de)
DK (1)	DK166879B1 (de)
ES (1)	ES2032284T3 (de)
FI (1)	FI91402C (de)
GR (1)	GR3003727T3 (de)
HK (1)	HK47193A (de)
HU (1)	HU202501B (de)
IE (1)	IE60044B1 (de)
IL (1)	IL84106A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2613720B1 (fr) *	1987-04-10	1990-01-19	Esteve Labor Dr	Derives d'aryl-heteroaryl carbinols avec activite analgesique
JPH01316317A (ja) *	1988-03-10	1989-12-21	Tanabe Seiyaku Co Ltd	降圧剤
US4956379A (en) *	1990-02-13	1990-09-11	Bristol-Myers Squibb Company	Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
CA2036192A1 (en)	1990-02-13	1991-08-14	Nicholas Meanwell	Heterocyclic carboxylic acids and esters
US20040067531A1 (en) *	1997-08-20	2004-04-08	Sugen, Inc.	Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
HRP20020751B1 (hr)	2000-02-15	2011-01-31	Sugen	Pirolom supstituirani 2-indolinoni kao inhibitori protein kinaze
AR042586A1 (es) *	2001-02-15	2005-06-29	Sugen Inc	3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
JP2005508953A (ja)	2001-10-10	2005-04-07	スージェン・インコーポレーテッド	キナーゼ阻害剤としての３−［４−（置換ヘテロサイクリル）−ピロール−２−イルメチリデン］−２−インドリノン誘導体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3342851A (en) *	1964-10-30	1967-09-19	Merck & Co Inc	Esters of [(2-methyleneacyl)phenoxy]-carboxylic acids and a method for their preparation
GB1415295A (en) *	1971-10-14	1975-11-26	Orchimed Sa	Substituted phenoxy-alkyl-carboxylic acids and derivatives thereof
CH543472A (fr) *	1969-01-31	1973-10-31	Orchimed Sa	Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
US4107179A (en) *	1977-08-22	1978-08-15	Smithkline Corporation	Method for preparing ticrynafen
GB2025942A (en) *	1978-05-31	1980-01-30	Sori Soc Rech Ind	Phenoxyalkylcarboxylic acids
US4323691A (en) *	1979-10-09	1982-04-06	Abbott Laboratories	Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters

1987
- 1987-10-05 US US07/105,173 patent/US4853404A/en not_active Expired - Fee Related
- 1987-10-06 IE IE266887A patent/IE60044B1/en not_active IP Right Cessation
- 1987-10-06 IL IL84106A patent/IL84106A/xx not_active IP Right Cessation
- 1987-10-09 JP JP62255347A patent/JPS63225359A/ja active Granted
- 1987-10-10 CN CN87106895A patent/CN1014787B/zh not_active Expired
- 1987-10-12 EP EP87114877A patent/EP0268800B1/de not_active Expired - Lifetime
- 1987-10-12 HU HU874600A patent/HU202501B/hu not_active IP Right Cessation
- 1987-10-12 FI FI874473A patent/FI91402C/fi not_active IP Right Cessation
- 1987-10-12 DK DK532987A patent/DK166879B1/da active
- 1987-10-12 KR KR1019870011259A patent/KR920002296B1/ko not_active Expired
- 1987-10-12 AT AT87114877T patent/ATE72429T1/de not_active IP Right Cessation
- 1987-10-12 DE DE8787114877T patent/DE3776627D1/de not_active Expired - Lifetime
- 1987-10-12 AU AU79563/87A patent/AU595385B2/en not_active Ceased
- 1987-10-12 ES ES198787114877T patent/ES2032284T3/es not_active Expired - Lifetime
- 1987-10-13 CA CA000549137A patent/CA1311483C/en not_active Expired - Lifetime
1992
- 1992-02-06 GR GR910401089T patent/GR3003727T3/el unknown
1993
- 1993-05-13 HK HK471/93A patent/HK47193A/xx unknown

Also Published As

Publication number	Publication date
IE60044B1 (en)	1994-05-18
FI91402B (fi)	1994-03-15
CA1311483C (en)	1992-12-15
ES2032284T3 (es)	1993-02-01
CN1014787B (zh)	1991-11-20
KR920002296B1 (ko)	1992-03-21
DK532987A (da)	1988-04-14
GR3003727T3 (de)	1993-03-16
FI874473L (fi)	1988-04-14
FI874473A0 (fi)	1987-10-12
DK532987D0 (da)	1987-10-12
HUT50788A (en)	1990-03-28
HK47193A (en)	1993-05-21
EP0268800A1 (de)	1988-06-01
FI91402C (fi)	1994-06-27
ATE72429T1 (de)	1992-02-15
AU595385B2 (en)	1990-03-29
DK166879B1 (da)	1993-07-26
US4853404A (en)	1989-08-01
IL84106A0 (en)	1988-03-31
EP0268800B1 (de)	1992-02-05
AU7956387A (en)	1988-04-14
JPS63225359A (ja)	1988-09-20
KR880005089A (ko)	1988-06-28
IE872668L (en)	1988-04-13
CN87106895A (zh)	1988-04-20
JPH0544944B2 (de)	1993-07-07
DE3776627D1 (de)	1992-03-19
HU202501B (en)	1991-03-28

Legal Events

Date	Code	Title	Description
1998-10-30	RH	Patent void

Publication	Publication Date	Title
EP0256503A3 (en)	1989-07-19	Pyridinecarboxamide derivatives and their use as fungicide
GR3002867T3 (en)	1993-01-25	Naphthalene derivatives, process for their preparation and pharmaceutical compositions containing the same
GR3005315T3 (de)	1993-05-24
MY101801A (en)	1992-01-31	Novel phenoxyacetic acid derivatives, process for preparing the same and pharmaceutical composition having the same as an active ingredient.
ATE158795T1 (de)	1997-10-15	Thiazolidindionderivate, ihre herstellung und anwendung
IE820556L (en)	1982-09-10	Benzofurans
IE890479L (en)	1989-08-16	Benzodioxoles
IL84106A0 (en)	1988-03-31	Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them
IE792329L (en)	1980-06-07	Thiazaheterocyclics and process for preparing pyrrolidine¹and piperidine derivatives.
HK10292A (en)	1992-01-31	Intermediates for agriculturally useful acrylic acid derivatives
EP0331078A3 (de)	1990-09-12	Verfahren zur Herstellung von optisch wirksamer 4-Oxo-1-Benzopyran-2-carbonsäure und deren Zwischenprodukte
NZ229186A (en)	1990-10-26	4-(1-(2-carboxy-3-(2-methoxyethoxy)propyl)-1-cyclopentane-
AU589698B2 (en)	1989-10-19	Novel 3(2H)-pyridazinone derivatives, pharmaceutical compositions containing them and process for preparing same
JPS5772970A (en)	1982-05-07	Azolylalkyl derivatives, manufacture and use as fungicide
AU585981B2 (en)	1989-06-29	Benzo (IJ) quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and processes for preparing the same
AU620244B2 (en)	1992-02-13	Novel pyridine derivatives and the use thereof as fungicides
IL87107A0 (en)	1988-12-30	Naphthothiazepine derivatives,their preparation and pharmaceutical compositions containing them
EP0180416A3 (de)	1986-11-20	Benzoesäurederivate und deren Produktion
NO855383L (no)	1986-07-14	Fremgangsmaate for fremstilling av piperazin-derivater.
IT1203951B (it)	1989-02-23	Composizioni antiinfiammatorie-analgesiche contenenti un derivato dell'acido naftil acetico
IE883879L (en)	1989-06-30	2-amino-tetrahydro-isoquinoline derivatives and a process for the preparation thereof and pharmaceutical compositions containing same
JPS54100384A (en)	1979-08-08	Novel penicillamine derivative
JPS5540652A (en)	1980-03-22	Phosphoryl-ethanolamine derivative
JPS5559170A (en)	1980-05-02	Novel 4-formyl-2-phenyl-1-phthalazone derivative