ATE75053T1 - Immunotest fuer biologisch wirksames menschliches interferon-gamma. - Google Patents

Immunotest fuer biologisch wirksames menschliches interferon-gamma.

Info

Publication number
ATE75053T1
ATE75053T1 AT85900850T AT85900850T ATE75053T1 AT E75053 T1 ATE75053 T1 AT E75053T1 AT 85900850 T AT85900850 T AT 85900850T AT 85900850 T AT85900850 T AT 85900850T AT E75053 T1 ATE75053 T1 AT E75053T1
Authority
AT
Austria
Prior art keywords
gamma
biologically active
huifn
human interferon
immunotest
Prior art date
Application number
AT85900850T
Other languages
English (en)
Inventor
Tse Wen Chang
Patrick C Kung
Junming Le
Victor Liu
Jan Vilcek
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Application granted granted Critical
Publication of ATE75053T1 publication Critical patent/ATE75053T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866—Interferon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT85900850T 1984-01-13 1985-01-10 Immunotest fuer biologisch wirksames menschliches interferon-gamma. ATE75053T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/570,353 US4666865A (en) 1984-01-13 1984-01-13 Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
PCT/US1985/000026 WO1985003133A1 (en) 1984-01-13 1985-01-10 Immunoassay for biologically active human interferon-gamma
EP85900850A EP0169234B1 (de) 1984-01-13 1985-01-10 Immunotest für biologisch wirksames menschliches interferon-gamma

Publications (1)

Publication Number Publication Date
ATE75053T1 true ATE75053T1 (de) 1992-05-15

Family

ID=24279325

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85900850T ATE75053T1 (de) 1984-01-13 1985-01-10 Immunotest fuer biologisch wirksames menschliches interferon-gamma.

Country Status (7)

Country Link
US (1) US4666865A (de)
EP (1) EP0169234B1 (de)
JP (1) JPS61501164A (de)
AT (1) ATE75053T1 (de)
CA (1) CA1242658A (de)
DE (1) DE3585853D1 (de)
WO (1) WO1985003133A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584418B1 (fr) * 1985-07-05 1988-11-10 Unicet Laboratoires Anticorps monoclonaux contre le g-interferon, hybridomes produisant de tels anticorps, procede de preparation de tels anticorps et de tels hybridomes, leur utilisation pour differencier les gifs, et ensemble ou " kit " utilisant de tels anticorps
CA1299099C (en) * 1986-03-06 1992-04-21 Paul Richard Wood In vitro assay for detecting cell-mediated immune responses
DE3642096A1 (de) * 1986-12-10 1988-06-16 Boehringer Ingelheim Int Pferde-(gamma)-interferon
CA1335792C (en) * 1987-08-18 1995-06-06 Chaim O. Jacob Method and dosage form using an antagonist to gamma interferon to control mhc-associated autoimmune disease
US5830709A (en) * 1989-10-27 1998-11-03 Benson; Roger E. Detection method for homologous portions of a class of substances
US5196311A (en) * 1989-10-27 1993-03-23 Health Research, Incorporated Elisa test for von willebrand factor
US5202264A (en) * 1989-10-27 1993-04-13 Health Research, Incorporated ELISA using multi-species antibodies for detection of von Willebrand factor in multiple species
WO2001019989A2 (en) * 1999-09-14 2001-03-22 Entremed, Inc. Method of producing and purifying endostatintm protein
WO2002097440A2 (de) * 2001-05-29 2002-12-05 Reinhold Kiehl Verfahren zur bestimmung von peptiden/proteinen, massenspektrometrie für metalle und leitfähigkeitsfeststellung
US7084257B2 (en) * 2001-10-05 2006-08-01 Amgen Inc. Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
US7229614B2 (en) * 2002-07-03 2007-06-12 The Brigham And Women's Hospital, Inc. Interferon gamma in the detection and treatment of angiomyolipomas
WO2005118884A1 (en) * 2004-05-28 2005-12-15 The United States Of America As Represented By The Secretary Of The Navy A method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
EP1849005A1 (de) * 2005-01-17 2007-10-31 Gyros Patent Ab Verfahren zum nachweis eines wenigstens bivalenten analyten unter verwendung von zwei affinitätsreaktanden
US11672877B2 (en) * 2017-08-23 2023-06-13 Wayne State University In vivo immunoimaging of interferon-gamma
US20210301020A1 (en) 2018-07-24 2021-09-30 Amgen Inc. Combination of lilrb1/2 pathway inhibitors and pd-1 pathway inhibitors
CN109781972B (zh) * 2019-01-16 2022-02-18 深圳大学 一种免疫定量检测方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS604423B2 (ja) * 1976-12-15 1985-02-04 持田製薬株式会社 ペプチドホルモンの定量方法
US4423147A (en) * 1980-04-11 1983-12-27 Secher David S Monoclonal antibody to interferon-α
JPH0611235B2 (ja) * 1980-04-11 1994-02-16 セルテック・リミテッド モノクロ−ナル抗体
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
SE8006424L (sv) * 1980-09-12 1982-03-13 Jolla Cancer Res Found Sett att bestemma ett antigen i losning
JPS5767858A (en) * 1980-10-15 1982-04-24 Takeda Chem Ind Ltd Immunochemical measurement method for human chorionic gonadotropin and production of antibody
WO1982001773A1 (en) * 1980-11-07 1982-05-27 Secher David S Assay for interferon
EP0071635B1 (de) * 1981-01-30 1986-04-30 Centocor, Inc. Immunotestverfahren für multibestimmende antigene
ES511156A0 (es) * 1981-04-13 1983-08-01 Hoechst Co American Un metodo de determinar la presencia de un antigeno en un medio liquido sospechoso de contenerlo.
CA1209907A (en) * 1982-04-12 1986-08-19 Richard M. Bartholomew Method of affinity purification employing monoclonal antibodies
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same
FR2755603B1 (fr) * 1996-11-12 1999-02-26 Jacques Preaut Ensemble d'ancillaires pour la pose de cotyles de protheses de hanche, et ensemble prothetique de cotyle pret a etre pose

Also Published As

Publication number Publication date
CA1242658A (en) 1988-10-04
EP0169234B1 (de) 1992-04-15
DE3585853D1 (de) 1992-05-21
JPS61501164A (ja) 1986-06-12
US4666865A (en) 1987-05-19
WO1985003133A1 (en) 1985-07-18
EP0169234A1 (de) 1986-01-29

Similar Documents

Publication Publication Date Title
ATE75053T1 (de) Immunotest fuer biologisch wirksames menschliches interferon-gamma.
KR900702007A (ko) T세포 항원 수용체의 지어부위와 반응하는 단클론항체
NL300387I1 (nl) Antilichaam tegen menselijke interleukine-6-receptor
DE3173597D1 (en) Specific antibody and its use in an enzyme immuno assay
FI972390A0 (fi) Sytokiini nimeltä Lerk-7
ATE47155T1 (de) Monoklonaler antikoerper.
GB1526241A (en) Fluorescence quenching with immunological pairs in immunoassays
DE3686187D1 (de) Monoklonale choriokarzinom-antikoerper und antikoerpergarnitur.
NO162179C (no) Monoklonale antistoffer for anvendelse in vitro.
OA08485A (fr) Monoclonal antibodies and antigen for human non-small cell lung carcinoma and certain other human carcinomas.
ATE67313T1 (de) Nachweis von menschlichem cytomegalovirusspezifischem igm.
GB2083836A (en) Monoclonal antibody
DE3684578D1 (de) Monoklonale antikoerper mit bindungsspezifitaet fuer menschliche prostatatumorantigene und methoden fuer ihre verwendung.
ATE48037T1 (de) Verfahren und reagenz zur verwendung zur bestimmung von pivka-ii.
ATE51709T1 (de) Antigen im zusammenhang mit der fruehzeitigen feststellung von schwangerschaft bei saeugern.
DE3579009D1 (de) Adult-t-zell-leukemiavirus-antigenpolypeptid.
NL7713692A (nl) Verbeteringen in en met betrekking tot enzym-ge- koppelde immuno-analyses.
FI883778A7 (fi) Tyyppiä III olevan prokollageenin propeptidin vasta-aine ja määritysenetelmä, jossa sitä käytetään.
FI891953L (fi) Monoklonaalinen vasta-aine intaktin prokollageenipeptidin (tyyppi III) ja prokollageenin (tyyppi III) selektiiviseksi immunologiseksi määrittämiseksi ruumiinnesteistä
NO873774D0 (no) Monoklonale eller polyklonale antistoffer.
DE3884646D1 (de) Humanes Karcinom-assoziertes Antigen und an dieses Antigen bindende Antikörper.
DK105085A (da) Monoklonalt antistof samt hybridom-cellelinie, der udskiller dette
DK151119C (da) Gasfoelerarrangement med foroeget sensivitet
NO903681D0 (no) Monoklonale antistoffer mot aktiverte ras-proteiner med aminosyremutasjoner i posisjon 13 i proteinet.
DE3586808D1 (de) L-thyroxin erkennende monoklonale antikoerper.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee