ATE82525T1 - Kieseltraeger. - Google Patents

Kieseltraeger.

Info

Publication number
ATE82525T1
ATE82525T1 AT85110571T AT85110571T ATE82525T1 AT E82525 T1 ATE82525 T1 AT E82525T1 AT 85110571 T AT85110571 T AT 85110571T AT 85110571 T AT85110571 T AT 85110571T AT E82525 T1 ATE82525 T1 AT E82525T1
Authority
AT
Austria
Prior art keywords
chemical group
compound
synthetic polymer
silica
ionizable
Prior art date
Application number
AT85110571T
Other languages
English (en)
Inventor
Kenneth C Hou
Tung-Ping D Liao
Original Assignee
Cuno Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cuno Inc filed Critical Cuno Inc
Application granted granted Critical
Publication of ATE82525T1 publication Critical patent/ATE82525T1/de

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/103—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/14—Diatomaceous earth
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
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    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3092—Packing of a container, e.g. packing a cartridge or column
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J39/17—Organic material containing also inorganic materials, e.g. inert material coated with an ion-exchange resin
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    • B01D15/3804—Affinity chromatography
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2220/58—Use in a single column

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymerisation Methods In General (AREA)
  • Graft Or Block Polymers (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Silicon Compounds (AREA)
AT85110571T 1984-08-22 1985-08-22 Kieseltraeger. ATE82525T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/643,613 US4724207A (en) 1984-02-02 1984-08-22 Modified siliceous chromatographic supports
EP85110571A EP0172579B1 (de) 1984-08-22 1985-08-22 Kieselträger

Publications (1)

Publication Number Publication Date
ATE82525T1 true ATE82525T1 (de) 1992-12-15

Family

ID=24581570

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85110571T ATE82525T1 (de) 1984-08-22 1985-08-22 Kieseltraeger.

Country Status (5)

Country Link
US (1) US4724207A (de)
EP (1) EP0172579B1 (de)
JP (1) JPS61166861A (de)
AT (1) ATE82525T1 (de)
DE (1) DE3586838T2 (de)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3619303A1 (de) * 1986-06-07 1987-12-10 Merck Patent Gmbh Optisch aktive adsorbentien
US4882226A (en) * 1986-09-23 1989-11-21 Akzo N.V. Carrier material for use in chromatography or carrying out enzymatic reactions
JP2509542B2 (ja) * 1987-02-26 1996-06-19 株式会社ワイエムシィ 溶質分離用担体
FR2616437B1 (fr) * 1987-06-11 1990-09-07 Ibf Polymeres composites, leur preparation et leur utilisation en chromatographie liquide
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
US5153166A (en) * 1988-08-18 1992-10-06 Trustees Of At Biochem Chromatographic stationary supports
US5240601A (en) * 1988-11-09 1993-08-31 Chembiomed, Ltd. Affinity supports for hemoperfusion
US5149425A (en) * 1988-11-09 1992-09-22 Chembiomed, Ltd. Affinity supports for hemoperfusion
AU5542390A (en) * 1989-04-11 1990-11-05 Cuno Incorporated Heavy metal removal filters
US4908137A (en) * 1989-04-11 1990-03-13 Cuno, Incorporated Heavy metal removal process
US5045210A (en) * 1989-04-11 1991-09-03 Cuno, Incorporated Heavy metal removal process
DE3926539A1 (de) * 1989-08-11 1991-02-14 Braun Melsungen Ag Verwendung von tentakel-kationenaustauschern zur selektiven eliminierung von low-density-lipoproteinen (ldl), fibrinogen und/oder harnstoff aus fluessigkeiten
JP2619537B2 (ja) * 1989-09-18 1997-06-11 株式会社日立製作所 液体クロマトグラフの方法，その装置，そのシステム，及びその分離カラム
AU6441490A (en) * 1989-09-18 1991-04-18 Cuno Incorporated Filter media and use for pyrogen removal
DE4139747A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Fuellstoffhaltige, optisch aktive perlpolymerisate
US5906734A (en) * 1992-06-19 1999-05-25 Biosepra Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5445732A (en) * 1992-06-19 1995-08-29 Sepracor Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5470463A (en) * 1992-06-19 1995-11-28 Sepracor Inc. Passivated porous supports and methods for the preparation and use of same
FR2716263B1 (fr) * 1994-02-11 1997-01-17 Pasteur Institut Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon.
ATA43094A (de) * 1994-03-01 1995-04-15 Chemiefaser Lenzing Ag Verfahren zur herstellung cellulosischer formkörper, lösung eines tert. aminoxids und ihre aufarbeitung
US5629186A (en) * 1994-04-28 1997-05-13 Lockheed Martin Corporation Porous matrix and method of its production
US5652348A (en) * 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
US6207066B1 (en) * 1996-07-23 2001-03-27 Nuvue Technologies, L.L.C. Method for purification of a blood component
US6210570B1 (en) 1998-08-21 2001-04-03 Agilent Technologies, Inc. Monolithic silica column
US6156431A (en) * 1999-01-04 2000-12-05 United Chemical Technologies, Inc. Extraction material comprising treated silica and method for determination of gamma-hydroxybutyrate
EP1147226B1 (de) 1999-01-27 2013-01-23 Folim G. Halaka Materialien und verfahren zur reinigung von polyelektrolyten
US6686035B2 (en) * 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
EP1733786B1 (de) * 1999-02-05 2010-04-14 Waters Technologies Corporation Poröse hybridpartikel zur chromatographischen trennung
US6248537B1 (en) 1999-05-28 2001-06-19 Institut Pasteur Use of the combing process for the identification of DNA origins of replication
AU2001274146A1 (en) * 2000-05-29 2001-12-11 Bio Merieux Biocompatible polymer for fixing biological ligands
DE60237251D1 (de) 2001-01-29 2010-09-23 Tosoh Corp Kationenaustauscher, Verfahren zu dessen Herstellung und dessen Verwendung
US6528167B2 (en) 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US7250214B2 (en) 2001-08-09 2007-07-31 Waters Investments Limited Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation
FR2834227A1 (fr) * 2001-12-27 2003-07-04 Chiralsep Sarl Materiaux supports optiquement actifs, leur procede de preparation et leurs utilisations
US20040224329A1 (en) * 2003-05-08 2004-11-11 Gjerde Douglas T. Three-dimensional solid phase extraction surfaces
US6855263B2 (en) * 2002-07-23 2005-02-15 Nuvue Technologies, Inc. Rapid process for purification and concentration of plasmin
US7264728B2 (en) * 2002-10-01 2007-09-04 Dow Corning Corporation Method of separating components in a sample using silane-treated silica filter media
WO2004041398A2 (en) 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
AU2003300295A1 (en) * 2002-12-20 2004-07-22 Cardiac Inventions Unlimited, Inc. Left ventricular pacing lead and implantation method
EP1645597A1 (de) * 2003-07-09 2006-04-12 Tokyo University of Science, Educational Foundation Konjugat von feinen porösen teilchen mit polymermolekülen und verwendung davon
WO2005011867A2 (en) 2003-07-31 2005-02-10 Handylab, Inc. Processing particle-containing samples
DE112005000269T5 (de) * 2004-02-17 2007-01-25 Waters Investments Ltd., New Castle Poröse Hybridmonolithmaterialien mit von der Oberfläche entfernten organischen Gruppen
US8852862B2 (en) * 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
DE112005001838B4 (de) * 2004-07-30 2018-11-29 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Poröse anorganische/organische Hybridmaterialien mit geordneten Domänen für chromatographische Auftrennungen, Verfahren für deren Herstellung sowie Auftrennvorrichtung und chromatographische Säule
US10773186B2 (en) 2004-07-30 2020-09-15 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
JP5217437B2 (ja) * 2005-09-27 2013-06-19 住友ベークライト株式会社 医療用粒子及びその製造方法
US9308520B2 (en) * 2005-12-16 2016-04-12 Akzo Nobel N.V. Silica based material
CN101365948B (zh) * 2006-01-06 2012-11-07 Emd密理博公司 亲和层析基质及其制备和使用方法
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
DK3088083T3 (en) 2006-03-24 2018-11-26 Handylab Inc Method of carrying out PCR down a multi-track cartridge
US8709787B2 (en) 2006-11-14 2014-04-29 Handylab, Inc. Microfluidic cartridge and method of using same
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
JP2010515804A (ja) 2007-01-12 2010-05-13 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフ分離用多孔質炭素−ヘテロ原子−ケイ素ハイブリッド無機／有機材料およびその調製のための方法
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
AU2008276211B2 (en) 2007-07-13 2015-01-22 Handylab, Inc. Polynucleotide capture materials, and methods of using same
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
JP5632282B2 (ja) * 2007-08-02 2014-11-26 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ Ｎ，ｎ−ジエチルアミノエチルメタクリラートをベースとする水性ポリマーディスパージョン、その調製及び使用
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
WO2010141426A1 (en) 2009-06-01 2010-12-09 Waters Technologies Corporation Hybrid material for chromatographic separations
JP5780622B2 (ja) * 2009-12-22 2015-09-16 国立大学法人 新潟大学 抗菌剤およびその製造方法
US20130112605A1 (en) 2010-07-26 2013-05-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
US20130225701A1 (en) * 2010-07-29 2013-08-29 Emd Millipore Corporation Grafting method to improve chromatography media performance
ES2769028T3 (es) 2011-04-15 2020-06-24 Becton Dickinson Co Termociclador microfluídico de barrido en tiempo real
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
ES2645966T3 (es) 2011-09-30 2017-12-11 Becton, Dickinson And Company Tira reactiva unificada
CN104040238B (zh) 2011-11-04 2017-06-27 汉迪拉布公司 多核苷酸样品制备装置
AU2013214849B2 (en) 2012-02-03 2016-09-01 Becton, Dickinson And Company External files for distribution of molecular diagnostic tests and determination of compatibility between tests
EP2811983B1 (de) 2012-09-17 2019-05-01 W.R. Grace & CO. - CONN. Trägermaterial in form funktionalisierter teilchen und verfahren zur herstellung und verwendung davon
EP2812091B1 (de) 2012-09-17 2021-03-10 W.R. Grace & CO. - CONN. Chromatographiemedien und -vorrichtungen
CN104736236B (zh) * 2012-11-01 2017-06-13 默克专利股份公司 多孔基体支持物的表面修饰
US9216403B2 (en) 2013-03-15 2015-12-22 Dionex Corporation Epoxy chemistry derived materials as reversed-phase and hydrophobic interaction chromatography media, method for their synthesis and use
US9329158B2 (en) 2013-03-15 2016-05-03 Dionex Corporation Epoxy chemistry derived materials as mixed mode chromatography media, method for their synthesis and use
EP3022262B1 (de) * 2013-09-06 2021-01-06 The Regents of The University of California Metalloxidteilchen mit gleichmässigen mehrschichtigen polymerbeschichtungen
WO2015105189A1 (ja) * 2014-01-10 2015-07-16 旭化成ケミカルズ株式会社 水性複合粒子分散体
ES2887110T3 (es) 2014-01-16 2021-12-21 Grace W R & Co Medios para cromatografía de afinidad y dispositivos para cromatografía
WO2015133507A1 (ja) * 2014-03-05 2015-09-11 Jsr株式会社 固相担体、リガンド結合固相担体、標的物質の検出又は分離方法、固相担体の製造方法、及びリガンド結合固相担体の製造方法
PL3137209T3 (pl) * 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego
EP3288900A1 (de) 2015-05-01 2018-03-07 Teledyne Scientific & Imaging, LLC Beschichtete granulierte filtrierungsmedien
KR102566292B1 (ko) 2015-06-05 2023-08-10 더블유.알. 그레이스 앤드 캄파니-콘. 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법
US20190015815A1 (en) 2016-03-06 2019-01-17 Waters Technologies Corporation Superficially porous materials comprising a coated core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
US11111398B2 (en) 2017-01-11 2021-09-07 International Business Machines Corporation Subsurface modified silica materials
CN113318714A (zh) * 2021-05-26 2021-08-31 浙江月旭材料科技有限公司 一种色谱用单分散二氧化硅微球及其制备方法和用途

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3251475A (en) * 1955-04-18 1966-05-17 Fmc Corp Fibrous filter body
GB1000038A (de) * 1960-12-06
NL130162C (de) * 1962-08-06
US3353682A (en) * 1966-02-28 1967-11-21 Pall Corp Fluid-permeable fibrous multilayer materials and process of making the same
US3488922A (en) * 1968-10-10 1970-01-13 Du Pont Method and apparatus for chromatographic separations with superficially porous glass beads having sorptively active crusts
US3772181A (en) * 1968-11-29 1973-11-13 Texaco Inc Process for treating water-soluble organic wastes
US3577266A (en) * 1969-01-13 1971-05-04 Du Pont Superficially porous chromatographic packing with sulfonated fluoropolymer coating
DE1902226A1 (de) * 1969-01-17 1970-07-23 Dr Istvan Halasz Stationaere Phase fuer die Chromatographie fuer Ionenaustauscher oder Katalysatoren
US3583855A (en) * 1969-04-28 1971-06-08 Deering Milliken Res Corp Modification of keratinic fibers with ethylenically unsaturated compounds
US3651210A (en) * 1970-05-15 1972-03-21 Ashland Oil Inc Synthetic emulsion-graft copolymers further reacted with protein
US3795313A (en) * 1970-05-22 1974-03-05 Du Pont Chromatographic packing with chemically bonded organic stationary phases
US3984349A (en) * 1971-07-26 1976-10-05 Societe Rhone-Progil Modified porous bodies
US3808125A (en) * 1972-08-25 1974-04-30 Phillips Petroleum Co Chromatographic apparatus
US3878092A (en) * 1973-03-12 1975-04-15 Phillips Petroleum Co Chromatographic colums
US4070348A (en) * 1973-07-25 1978-01-24 Rohm Gmbh Water-swellable, bead copolymer
US3983299A (en) * 1974-03-04 1976-09-28 Purdue Research Foundation Bonded carbohydrate stationary phases for chromatography
FR2283101A1 (fr) * 1974-08-30 1976-03-26 Rhone Poulenc Ind Supports mineraux modifies
US4029583A (en) * 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
US4100149A (en) * 1975-08-28 1978-07-11 Rhone-Poulenc Industries Method of separating proteins by ion exchange
US4102746A (en) * 1975-08-29 1978-07-25 Amerace Corporation Immobilized proteins
US4140653A (en) * 1975-09-30 1979-02-20 Toyo Soda Manufacturing Co., Ltd. Solid support for liquid chromatography
US4309247A (en) * 1976-03-15 1982-01-05 Amf Incorporated Filter and method of making same
US4086190A (en) * 1976-04-19 1978-04-25 Blount David H Process for the production of silicic epoxy polymers
US4144190A (en) * 1976-07-08 1979-03-13 Ciba-Geigy Ag Polysaccharide-containing adsorbent
US4118316A (en) * 1976-10-13 1978-10-03 Calgon Corporation Quaternized siliceous supports for gel permeation chromatography
SE7712058L (sv) * 1976-11-12 1978-05-13 Ceskoslovenska Akademie Ved Tredimensionell berare av oorganiskt, porost material och en reaktiv polymer och ett forfarande for framstellning derav
US4344775A (en) * 1979-03-08 1982-08-17 Max Klein Method for separating gases liquid droplets and/or solid particles from gases or vapors
CA1148872A (en) * 1979-04-06 1983-06-28 Eugene A. Ostreicher Filter with inorganic cationic colloidal silica
JPS56115727A (en) * 1980-02-19 1981-09-11 Kuraray Co Ltd Carrier for immobilizing physiologically active substance
US4384954A (en) * 1980-04-16 1983-05-24 Kuraray Co., Ltd. Column for adsorption of blood proteins
US4298500A (en) * 1980-05-05 1981-11-03 Varian Associates, Inc. Mixed phase chromatographic compositions
DE3172131D1 (en) * 1980-06-27 1985-10-10 Akzo Nv Porous inorganic support material coated with an organic stationary phase, for use in chromatography, and process for its preparation
US4262108A (en) * 1980-07-18 1981-04-14 Blount David H Process for the production of polyisocyanate silicate plastics utilizing an alkali metal cellulose silicate condensation product
US4384957A (en) * 1980-09-08 1983-05-24 Amf Incorporated Molecular separation column and use thereof
US4449978A (en) * 1981-08-31 1984-05-22 Air Products And Chemicals, Inc. Nonwoven products having low residual free formaldehyde content
AU580548B2 (en) * 1983-02-14 1989-01-19 Cuno Incorporated Polymer modified polysaccharide

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EP0172579A2 (de) 1986-02-26
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DE3586838D1 (de) 1992-12-24
EP0172579B1 (de) 1992-11-19
JPS61166861A (ja) 1986-07-28
US4724207A (en) 1988-02-09

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