ATE84036T1 - Porphyrinderivate, ihre herstellung und verwendung. - Google Patents

Porphyrinderivate, ihre herstellung und verwendung.

Info

Publication number: ATE84036T1
Authority: AT; Austria
Prior art keywords: sub; coo; residue; lower alkylene; compound
Prior art date: 1985-10-23

Application number

AT86114732T

Other languages

English (en)

Inventor

Isao Sakata

Susumu Nakajima

Koichi Koshimizu

Natsuki Samejima

Kazumi Inohara

Hiroyuki Takata

Hirohiko Yamauchi

Nobuo Ueda

Masaaki Hazue

Original Assignee

Nihon Mediphysics Co Ltd

Toyo Hakka Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-23

Filing date

1986-10-23

Publication date

1993-01-15

1986-10-23 Application filed by Nihon Mediphysics Co Ltd, Toyo Hakka Kogyo Kk filed Critical Nihon Mediphysics Co Ltd

1993-01-15 Application granted granted Critical

1993-01-15 Publication of ATE84036T1 publication Critical patent/ATE84036T1/de

Links

150000004033 porphyrin derivatives Chemical class 0.000 title 1
-1 porphyrin compound Chemical class 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 3
206010028980 Neoplasm Diseases 0.000 abstract 1
238000009825 accumulation Methods 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000029142 excretion Effects 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
JZRYQZJSTWVBBD-UHFFFAOYSA-N pentaporphyrin i Chemical group N1C(C=C2NC(=CC3=NC(=C4)C=C3)C=C2)=CC=C1C=C1C=CC4=N1 JZRYQZJSTWVBBD-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT86114732T 1985-10-23 1986-10-23 Porphyrinderivate, ihre herstellung und verwendung. ATE84036T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP23532385		1985-10-23
JP23532285		1985-10-23
EP86114732A EP0220686B1 (de)	1985-10-23	1986-10-23	Porphyrinderivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number	Publication Date
ATE84036T1 true ATE84036T1 (de)	1993-01-15

Family

ID=26532056

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86114732T ATE84036T1 (de)	1985-10-23	1986-10-23	Porphyrinderivate, ihre herstellung und verwendung.

Country Status (7)

Country	Link
US (2)	US4849207A (de)
EP (1)	EP0220686B1 (de)
KR (1)	KR910009202B1 (de)
AT (1)	ATE84036T1 (de)
AU (1)	AU603999B2 (de)
CA (1)	CA1311239C (de)
DE (1)	DE3687399T2 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4672028A (en) *	1984-05-23	1987-06-09	Icn Micromedic Systems, Inc.	Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels
EP0220686B1 (de) *	1985-10-23	1992-12-30	Nihon Medi-Physics Co., Ltd.	Porphyrinderivate, ihre Herstellung und Verwendung
US5534506A (en) *	1986-01-02	1996-07-09	University Of Toledo	Use of purpurins, chlorins and purpurin- and chlorin-containing compositions
US5216012A (en) *	1986-01-02	1993-06-01	University Of Toledo	Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions
US4772681A (en) *	1986-01-17	1988-09-20	Hamari Chemicals, Ltd.	Porphyrin derivatives
JPH0786109B2 (ja) *	1987-12-21	1995-09-20	浜理薬品工業株式会社	フェオフォルバイド誘導体
CA1341460C (en) *	1988-01-11	2004-10-19	The Medical College Of Ohio	Production and use of porphyrin derivatives and of compositions containing such derivates
DE68928607T2 (de) *	1988-07-14	1998-07-23	Toyohakka Kogyo K K	Porphyrinderivate
US5198460A (en) *	1988-07-20	1993-03-30	Health Research Inc.	Pyropheophorbides and their use in photodynamic therapy
USRE39094E1 (en)	1988-07-20	2006-05-09	Health Research, Inc.	Pyropheophorbides and their use in photodynamic therapy
USRE38994E1 (en)	1988-07-20	2006-02-28	Health Research, Inc.	Pyropheophorbides conjugates and their use in photodynamic therapy
US5093349A (en) *	1988-07-20	1992-03-03	Health Research Inc.	Photosensitizing agents
US5002962A (en) *	1988-07-20	1991-03-26	Health Research, Inc.	Photosensitizing agents
DE3827940A1 (de) *	1988-08-13	1990-03-01	Schering Ag	13,17-propionsaeure- und propionsaeurederivat- substituierte porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5010451A (en) *	1989-03-29	1991-04-23	Mitsubishi Denki K.K.	Electronic device
US5173504A (en) *	1989-04-21	1992-12-22	Health Research, Inc.	Bacteriochlorophyll-a derivatives useful in photodynamic therapy
US5171741A (en) *	1989-04-21	1992-12-15	Health Research, Inc.	Bacteriochlorophyll-a derivatives useful in photodynamic therapy
US5064952A (en) *	1990-01-16	1991-11-12	Board Of Trustees, A Constitutional Corporation Operating Michigan State University	Derivatives of porphyrin useful in photodynamic therapy
US5214036A (en) *	1990-03-08	1993-05-25	University Of British Columbia	Benzoporphyrin derivatives for photodynamic therapy
US5132101A (en) *	1990-05-04	1992-07-21	Cytopharm, Inc.	Acetylene-cumulene porphycene compounds for photodynamic therapy
US5641878A (en) *	1991-05-15	1997-06-24	Diatron Corporation	Porphyrin, azaporphyrin, and related fluorescent dyes free of aggregation and serum binding
CA2082934C (en) *	1990-05-15	2003-08-05	Walter B. Dandliker	Phthalocyanatopolyethylene glycol, and phthalocyanato saccharides as fluorescent digoxin reagents
US5880287A (en) *	1990-05-15	1999-03-09	Hyperion, Inc.	Polyoxyhydrocarbyl related products and methods for fluorescence assays
US6060598A (en) *	1990-05-15	2000-05-09	Hyperion, Inc.	Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding
US5919922A (en) *	1990-05-15	1999-07-06	Hyperion, Inc.	Fluorescent dyes free of aggregation and serum binding
US5403928A (en) *	1990-05-15	1995-04-04	Diatron Corporation	Fluorescent marker components and fluorescent probes
US5149801A (en) *	1990-11-21	1992-09-22	The Regents Of The University Of California	Boronated porphyrin compounds
US5244671A (en) *	1991-01-29	1993-09-14	Cytopharm, Inc.	Derivatives of porphycene for photodynamic therapy of cancer
US5354858A (en) *	1991-03-28	1994-10-11	The University Of Toledo	Production and use of Diels Alder adducts of vinyl porphyrins and of compositions containing such adducts
US5179120A (en) *	1991-06-28	1993-01-12	Cytopharm, Inc.	Porphycene compounds for photodynamic therapy
DE4121876A1 (de) *	1991-07-02	1993-01-14	Scheer Hugo	Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung
PL165249B1 (pl) *	1991-10-29	1994-11-30	Wojskowa Akad Tech	Sposób otrzymywania soli kompleksowych hematoporfiryny i jej pochodnych PL PL PL PL PL PL PL
US5650134A (en) *	1993-01-12	1997-07-22	Novartis Ag (Formerly Sandoz Ltd.)	Peptides
US5368841A (en) *	1993-02-11	1994-11-29	The General Hospital Corporation	Photodynamic therapy for the destruction of the synovium in the treatment of rheumatoid arthritis and the inflammatory arthritides
US5492924A (en) *	1993-09-24	1996-02-20	Fox Chase Cancer Center	Phorbine derivatives and their use in the diagnosis and therapy of cancer
US5498710A (en) *	1994-04-22	1996-03-12	Health Research, Inc.	Alkyl ether analogues of benzoporphyrin derivatives
EP1091742A4 (de) *	1997-02-14	2007-05-30	Miravant Pharm Inc	Indium photosensibilisatoren zur pdt
JP2002534218A (ja) *	1999-01-15	2002-10-15	ライトサイエンシーズコーポレイション	非侵襲性の脈管療法
US6454789B1 (en) *	1999-01-15	2002-09-24	Light Science Corporation	Patient portable device for photodynamic therapy
US6602274B1 (en) *	1999-01-15	2003-08-05	Light Sciences Corporation	Targeted transcutaneous cancer therapy
MXPA01011008A (es) *	1999-04-30	2003-06-30	Slil Biomedical Corp	Conjugados analogos de poliamina y conjugados de quinona novedosos como terapia para canceres y enfermedades de la prostata.
US6649587B1 (en)	1999-04-30	2003-11-18	Slil Biomedical Corporation	Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
US6482943B1 (en)	1999-04-30	2002-11-19	Slil Biomedical Corporation	Quinones as disease therapies
US6548045B2 (en) *	1999-11-30	2003-04-15	Photochemical Co., Ltd.	Nitroimidazole substituted porphyrin complex
US6458336B1 (en)	2000-05-30	2002-10-01	The Trustees Of Columbia University In The City Of New York	Detectably labeled porphyrin compound for identifying the sentinel lymph node
AU2002235126A1 (en) *	2000-11-08	2002-05-21	Slil Biomedical Corporation	Novel polyamine analog-amino acid conjugates useful as anticancer agents
JP2004532251A (ja) *	2001-05-31	2004-10-21	ミラヴァントファーマシューティカルズインコーポレイテッド	光線力学療法で使用のメタロテトラピロール系光増感剤
WO2002096417A1 (en) *	2001-05-31	2002-12-05	Miravant Pharmaceuticals, Inc.	Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and mri diagnosis
US7087214B2 (en) *	2002-02-01	2006-08-08	Zentaris Gmbh	Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases
KR100484205B1 (ko) *	2003-01-16	2005-04-20	주식회사 테크노마트	포르피린 유도체
EP1594875A4 (de) *	2003-01-16	2007-07-11	Technomart Co Ltd	Porphyrinderivate

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2476358A (en) *	1945-05-09	1949-07-19	Ford Motor Co	Soluble compound of chlorophyll and synthesis thereof
DE1138053B (de) *	1957-02-07	1962-10-18	Daiichi Seiyaku Co	Verfahren zur Herstellung von Quecksilberporphyrinen und deren Dialkalisalzen
DE1226582B (de) *	1961-04-05	1966-10-13	Green Cross Corp	Verfahren zur Herstellung von Kobaltiprotoporphyrin
FR94M (fr) *	1964-11-06	1961-01-13	Henri Griffon	Nouveau médicament à base de levure vivante
US4649151A (en) *	1982-09-27	1987-03-10	Health Research, Inc.	Drugs comprising porphyrins
EP0120054B1 (de) *	1982-09-27	1990-05-30	Health Research, Inc.	Gereinigte hematoporphyrinabkömmlinge für diagnose und tumorbehandlung sowie verfahren
JPS6092287A (ja) *	1983-10-24	1985-05-23	Toyo Hatsuka Kogyo Kk	９−デスオキソ−９−ハイドロオキシ−フエオホ−バイド誘導体およびそれらのアルカリ塩類
DE3481125D1 (de) *	1983-10-24	1990-03-01	Toyo Hakka Kogyo Kk	Pheophorbidderivate und diese enthaltende pharmazeutische mittel.
JPS60152487A (ja) *	1984-01-18	1985-08-10	Sato Yakugaku Kenkyusho:Kk	デユウテロポルフイリン誘導体及びその塩
US4675338A (en) *	1984-07-18	1987-06-23	Nippon Petrochemicals Co., Ltd.	Tetrapyrrole therapeutic agents
US4657902A (en) *	1985-03-25	1987-04-14	The Rockefeller University	Therapeutic use of tin mesoporphyrin
EP0220686B1 (de) *	1985-10-23	1992-12-30	Nihon Medi-Physics Co., Ltd.	Porphyrinderivate, ihre Herstellung und Verwendung

1986
- 1986-10-23 EP EP86114732A patent/EP0220686B1/de not_active Expired - Lifetime
- 1986-10-23 DE DE8686114732T patent/DE3687399T2/de not_active Expired - Fee Related
- 1986-10-23 CA CA000521232A patent/CA1311239C/en not_active Expired - Lifetime
- 1986-10-23 AT AT86114732T patent/ATE84036T1/de not_active IP Right Cessation
- 1986-10-23 AU AU64333/86A patent/AU603999B2/en not_active Ceased
- 1986-10-23 KR KR1019860008885A patent/KR910009202B1/ko not_active Expired
- 1986-10-23 US US06/922,492 patent/US4849207A/en not_active Expired - Lifetime
1989
- 1989-04-19 US US07/340,549 patent/US4996312A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0220686A2 (de)	1987-05-06
DE3687399T2 (de)	1993-04-29
AU6433386A (en)	1987-04-30
DE3687399D1 (de)	1993-02-11
KR910009202B1 (ko)	1991-11-04
US4996312A (en)	1991-02-26
CA1311239C (en)	1992-12-08
EP0220686B1 (de)	1992-12-30
AU603999B2 (en)	1990-12-06
US4849207A (en)	1989-07-18
EP0220686A3 (en)	1988-10-19
KR870004021A (ko)	1987-05-07

Legal Events

Date	Code	Title	Description
2002-06-15	EEIH	Change in the person of patent owner
2005-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE84036T1 (de)	1993-01-15	Porphyrinderivate, ihre herstellung und verwendung.
DE69108138D1 (de)	1995-04-20	Imidazopyridinderivate und ihre Verwendung.
AU553338B2 (en)	1986-07-10	Redox indicators
CA2215310A1 (en)	1996-10-03	Substrates for beta-lactamase and uses thereof
CA1251209A (en)	1989-03-14	DISHYDROPYRIDAZINONE DERIVATIVES
HU9301197D0 (en)	1993-07-28	Medical preparatives containing quinoline and quinazoline derivatives as well as new quinoline and quinazoline derivatives
IE45631L (en)	1977-12-25	4-hydroxyphenylalkanolamine derivatives.
CA2196900A1 (en)	1996-02-15	Fluorinated 2-nitroimidazole analogs for detecting hypoxic tumor cells
ES8800683A1 (es)	1987-11-16	Un procedimiento para la preparacion de nuevos derivados penem
CA2281695A1 (en)	1998-08-27	Process for the preparation of substituted thiazolidinedione
IE831145L (en)	1983-11-18	Pyridine derivatives
AU529996B2 (en)	1983-06-30	Synthesis of vincaminic acid derivatives
CA2018769A1 (en)	1990-12-15	Adduct-aldehyde and its use for the preparation of a vitamin-d compound
AU600054B2 (en)	1990-08-02	2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m- phenylene pgi2 derivatives
IE780926L (en)	1978-11-09	Chromene derivatives
CA2307068A1 (en)	1999-04-29	Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
BG103705A (en)	2000-04-28	Phenoxyacetic acid derivatives and their application as herbicides
IE44708L (en)	1977-09-01	Esters of hydroxy alkoxyalkyl purines
ATE24487T1 (de)	1987-01-15	Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
CA2083143A1 (en)	1991-11-23	Process for the preparation of 7.alpha.-alkoxycephem derivatives
IE780982L (en)	1978-11-17	4-hydroxythiazoline-2-thiones.
JPS54122283A (en)	1979-09-21	Novel quinazoline derivative and its preparation
IE892884L (en)	1990-03-09	Microbicides
DE3770713D1 (de)	1991-07-18	8-phenylthiotetrahydrochinolin-derivate und ihre salze, ihre herstellung, verwendung als arzneimittel und zusammensetzungen davon.
JPS5498779A (en)	1979-08-03	5-formyl carbostyril derivative