ATE84876T1 - Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter. - Google Patents

Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter.

Info

Publication number
ATE84876T1
ATE84876T1 AT86302650T AT86302650T ATE84876T1 AT E84876 T1 ATE84876 T1 AT E84876T1 AT 86302650 T AT86302650 T AT 86302650T AT 86302650 T AT86302650 T AT 86302650T AT E84876 T1 ATE84876 T1 AT E84876T1
Authority
AT
Austria
Prior art keywords
waveguide
medium
detectors
optic
biological molecules
Prior art date
Application number
AT86302650T
Other languages
English (en)
Inventor
William James Stewart
Original Assignee
Marconi Gec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marconi Gec Ltd filed Critical Marconi Gec Ltd
Application granted granted Critical
Publication of ATE84876T1 publication Critical patent/ATE84876T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT86302650T 1985-04-12 1986-04-10 Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter. ATE84876T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858509491A GB8509491D0 (en) 1985-04-12 1985-04-12 Optic waveguide biosensors
EP86302650A EP0205236B1 (de) 1985-04-12 1986-04-10 Messfühler für biologische Moleküle mit Verwendung optischer Wellenleiter

Publications (1)

Publication Number Publication Date
ATE84876T1 true ATE84876T1 (de) 1993-02-15

Family

ID=10577584

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86302650T ATE84876T1 (de) 1985-04-12 1986-04-10 Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter.

Country Status (6)

Country Link
US (1) US4857273A (de)
EP (1) EP0205236B1 (de)
JP (1) JPH07117486B2 (de)
AT (1) ATE84876T1 (de)
DE (1) DE3687543T2 (de)
GB (2) GB8509491D0 (de)

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3001669A1 (de) * 1980-01-18 1981-08-06 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Anordnung zur optischen messung von physikalischen groessen und stoffkonzentrationen
WO1986007149A1 (de) * 1985-05-29 1986-12-04 Kurt Tiefenthaler Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahländerungen in messubstanzen
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
GB8714503D0 (en) * 1987-06-20 1987-07-22 Pa Consulting Services Detector
AU615928B2 (en) * 1987-06-20 1991-10-17 Applied Research Systems Ars Holding N.V. Waveguide sensor
JPS646842A (en) * 1987-06-30 1989-01-11 Ricoh Kk Detecting device
GB8801807D0 (en) * 1988-01-27 1988-02-24 Amersham Int Plc Biological sensors
DE68907519T2 (de) * 1988-05-10 1993-10-21 Amersham Int Plc Biosensoren.
GB8811919D0 (en) * 1988-05-20 1988-06-22 Amersham Int Plc Biological sensors
GB8813307D0 (en) * 1988-06-06 1988-07-13 Amersham Int Plc Biological sensors
GB8817710D0 (en) * 1988-07-25 1988-09-01 Ares Serono Res & Dev Ltd Method of assay
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
GB8827853D0 (en) * 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
GB2227089A (en) * 1989-01-11 1990-07-18 Plessey Co Plc An optical biosensor
GB2228082A (en) * 1989-01-13 1990-08-15 Marconi Gec Ltd Gas or liquid chemical sensor
US6010867A (en) * 1989-04-19 2000-01-04 Ibiden Co., Ltd. Reagent for biomaterials assay, preparation method thereof, and assay method
WO1990013029A1 (fr) * 1989-04-19 1990-11-01 Ibiden Co., Ltd. Reactif de dosage de substances biologiquement actives, son procede de production, procede et appareil de dosage
US5401469A (en) * 1989-04-19 1995-03-28 Ibiden Co., Ltd. Plastic optical biomaterials assay device
US5156810A (en) * 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
US5491097A (en) * 1989-06-15 1996-02-13 Biocircuits Corporation Analyte detection with multilayered bioelectronic conductivity sensors
DE3923921A1 (de) * 1989-07-19 1991-01-24 Biotechnolog Forschung Gmbh Optischer biosensor
DE4033741C2 (de) * 1989-11-02 1994-03-31 Falko Volkhardt E Dipl Tittel Vorrichtung zum Nachweis von HIV-Antikörpern im Vollblut mit Anzeige des Ergebnisses
GB8924951D0 (en) * 1989-11-04 1989-12-28 Fisons Plc Device and methods
US5075551A (en) * 1990-03-12 1991-12-24 Fuji Electric Co., Ltd. Infrared absorption enhanced spectroscopic apparatus
US5143066A (en) * 1990-05-08 1992-09-01 University Of Pittsburgh Optical fiber sensors for continuous monitoring of biochemicals and related method
EP0543831B1 (de) * 1990-08-17 1995-12-13 FISONS plc Vorrichtung zur analyse
GB9018195D0 (en) * 1990-08-18 1990-10-03 Fisons Plc Analytical device
GB2248497B (en) * 1990-09-26 1994-05-25 Marconi Gec Ltd An optical sensor
US5192510A (en) * 1991-01-30 1993-03-09 E. I. Du Pont De Nemours And Company Apparatus for performing fluorescent assays which separates bulk and evanescent fluorescence
US5271895A (en) * 1991-02-27 1993-12-21 Boehringer Mannheim Corporation Test strip
WO1992015863A1 (en) * 1991-02-27 1992-09-17 Boehringer Mannheim Corporation Improved test strip
EP0587568A1 (de) * 1991-03-09 1994-03-23 FISONS plc Analytische Verfahren und Vorrichtungen
GB2254415B (en) * 1991-03-22 1994-10-12 Marconi Gec Ltd An optical sensor
GB9111912D0 (en) * 1991-06-04 1991-07-24 Fisons Plc Analytical methods
GB2256477B (en) * 1991-06-07 1995-03-08 Marconi Gec Ltd An optical sensor
GB9120000D0 (en) * 1991-09-19 1991-11-06 British Gas Plc Optical sensing
US5354574A (en) * 1992-06-23 1994-10-11 Ibiden Co., Ltd. Method for producing optical fiber having formyl groups on core surface thereof
US6256522B1 (en) 1992-11-23 2001-07-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Sensors for continuous monitoring of biochemicals and related method
DE4411035A1 (de) * 1993-04-23 1994-11-03 Fraunhofer Ges Forschung Optischer Sensor
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
DE69404652T2 (de) 1993-05-28 1998-01-15 Fisons Plc Analysegerät
US5538850A (en) * 1994-04-15 1996-07-23 Hewlett-Packard Company Apparatus and method for intracavity sensing of microscopic properties of chemicals
US5437840A (en) * 1994-04-15 1995-08-01 Hewlett-Packard Company Apparatus for intracavity sensing of macroscopic properties of chemicals
JPH07318481A (ja) * 1994-05-25 1995-12-08 Daikin Ind Ltd 光学的測定方法およびその装置
US6287850B1 (en) * 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
JPH08116961A (ja) * 1994-10-25 1996-05-14 Hamamatsu Photonics Kk 培養観測用容器及び観測装置
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US5633724A (en) * 1995-08-29 1997-05-27 Hewlett-Packard Company Evanescent scanning of biochemical array
US5815278A (en) * 1995-10-25 1998-09-29 University Of Washington Surface plasmon resonance light pipe sensing probe and related interface optics
US6660233B1 (en) * 1996-01-16 2003-12-09 Beckman Coulter, Inc. Analytical biochemistry system with robotically carried bioarray
US5854863A (en) * 1996-03-15 1998-12-29 Erb; Judith Surface treatment and light injection method and apparatus
US6108463A (en) * 1996-03-19 2000-08-22 University Of Utah Research Foundation Lens and associatable flow cell
US5832165A (en) 1996-08-28 1998-11-03 University Of Utah Research Foundation Composite waveguide for solid phase binding assays
GB9618635D0 (en) * 1996-09-06 1996-10-16 Thermo Fast Uk Ltd Improvements in or relating to sensors
EP0834735A3 (de) * 1996-10-01 1999-08-11 Texas Instruments Inc. Sensor
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
JPH10221249A (ja) * 1996-12-05 1998-08-21 Norio Miura 薬物の測定装置とセンサ及び該センサに用いる検出素子
US6025189A (en) * 1997-05-14 2000-02-15 3M Innovative Properties Company Apparatus for reading a plurality of biological indicators
US6558956B1 (en) 1997-06-24 2003-05-06 The University Of Wyoming Method and apparatus for detection of a controlled substance
US6222619B1 (en) 1997-09-18 2001-04-24 University Of Utah Research Foundation Diagnostic device and method
US6100541A (en) 1998-02-24 2000-08-08 Caliper Technologies Corporation Microfluidic devices and systems incorporating integrated optical elements
US6429023B1 (en) 1998-07-20 2002-08-06 Shayda Technologies, Inc. Biosensors with polymeric optical waveguides
US6573107B1 (en) 1998-08-05 2003-06-03 The University Of Wyoming Immunochemical detection of an explosive substance in the gas phase through surface plasmon resonance spectroscopy
US6770488B1 (en) 1999-03-19 2004-08-03 The University Of Wyoming Practical method and apparatus for analyte detection with colloidal particles
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US6315958B1 (en) * 1999-11-10 2001-11-13 Wisconsin Alumni Research Foundation Flow cell for synthesis of arrays of DNA probes and the like
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
US20080220440A1 (en) * 2000-07-25 2008-09-11 M Selim Unlu Waveguide sensors optimized for discrimination against non-specific binding
US7384797B1 (en) * 2000-10-12 2008-06-10 University Of Utah Research Foundation Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods
WO2002033005A2 (en) * 2000-10-19 2002-04-25 Trans Photonics, L.L.C. Novel substituted-polyaryl chromophoric compounds
US7070987B2 (en) * 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7875434B2 (en) * 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US6951715B2 (en) * 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7175980B2 (en) * 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US7264973B2 (en) * 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7217574B2 (en) * 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7153702B2 (en) * 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7371562B2 (en) * 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7300803B2 (en) * 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7101660B2 (en) * 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US20030113766A1 (en) * 2000-10-30 2003-06-19 Sru Biosystems, Llc Amine activated colorimetric resonant biosensor
US7615339B2 (en) * 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7306827B2 (en) * 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US7023544B2 (en) * 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7202076B2 (en) * 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7118710B2 (en) * 2000-10-30 2006-10-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US20030092075A1 (en) * 2000-10-30 2003-05-15 Sru Biosystems, Llc Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors
US7142296B2 (en) * 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
WO2003036225A1 (en) * 2001-10-26 2003-05-01 University Of Rochester Method for biomolecular sensing and system thereof
US6707958B2 (en) * 2001-11-20 2004-03-16 Agilent Technologies, Inc. Biochemical assay device using frustrated total internal reflection modulator with an imaging optical waveguide
AU2003210523B2 (en) * 2002-01-28 2008-03-20 Sru Biosystems, Inc. A guided mode resonant filter biosensor using a linear grating surface structure
US7018842B2 (en) * 2002-02-28 2006-03-28 Agilent Technologies, Inc. Reading dry chemical arrays through the substrate
US7154598B2 (en) * 2002-07-12 2006-12-26 Decision Biomarkers, Inc. Excitation and imaging of fluorescent arrays
US20060127946A1 (en) * 2002-08-16 2006-06-15 Montagu Jean I Reading of fluorescent arrays
US7384742B2 (en) * 2002-08-16 2008-06-10 Decision Biomarkers, Inc. Substrates for isolating reacting and microscopically analyzing materials
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US7429492B2 (en) * 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
WO2004083820A2 (en) * 2003-03-19 2004-09-30 Trustees Of Boston University Resonant cavity biosensor
US8298780B2 (en) * 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
CA2544836A1 (en) * 2003-11-06 2005-05-26 Guo Bin Wang High-density amine-functionalized surface
GB0405823D0 (en) * 2004-03-15 2004-04-21 Evanesco Ltd Functionalised surface sensing apparatus and methods
US7709247B2 (en) * 2004-08-04 2010-05-04 Intel Corporation Methods and systems for detecting biomolecular binding using terahertz radiation
DE102004045902B4 (de) * 2004-09-22 2006-08-31 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur Messung der Lichtabsorption
US7551294B2 (en) * 2005-09-16 2009-06-23 University Of Rochester System and method for brewster angle straddle interferometry
DE102005062174C5 (de) * 2005-12-23 2010-05-06 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Meßchip
US8062595B2 (en) * 2006-02-06 2011-11-22 Stmicroelectronics S.R.L. Nucleic acid analysis chip integrating a waveguide and optical apparatus for the inspection of nucleic acid probes
US20070235397A1 (en) * 2006-03-30 2007-10-11 Wannop George M Storage bin and frame system
US7692798B2 (en) * 2006-09-15 2010-04-06 Adarza Biosystems, Inc. Method for biomolecular detection and system thereof
EP2092339B1 (de) * 2006-12-12 2012-05-16 Koninklijke Philips Electronics N.V. Mikroelektronische sensorvorrichtung zum nachweis markierter partikel
CA2683082A1 (en) * 2007-04-19 2008-10-30 Sru Biosystems, Inc. Method for employing a biosensor to detect small molecules that bind directly to immobilized targets
DE102007025513B4 (de) * 2007-06-01 2014-06-05 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Vorrichtung und Verfahren zum Ermöglichen der Bewertung eines Füllzustands
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
AU2008274978A1 (en) 2007-07-11 2009-01-15 Sru Biosystems, Inc. Methods of identifying modulators of ion channels
US8257936B2 (en) * 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
WO2009149285A1 (en) * 2008-06-04 2009-12-10 Sru Biosystems, Inc. Detection of promiscuous small submicrometer aggregates
EP2331934B1 (de) 2008-09-16 2020-01-01 Pacific Biosciences of California, Inc. Analysegerät mit Nullmoden-Wellenleiter Substrat
EP2430448A1 (de) * 2009-05-15 2012-03-21 SRU Biosystems, Inc. Nachweis von änderungen von zellpopulationen und gemischten zellpopulationen
US8694069B1 (en) 2009-12-21 2014-04-08 Kosense, LLC Fiber-optic probe with embedded peripheral sensors for in-situ continuous monitoring
US8750652B2 (en) * 2010-10-12 2014-06-10 The Board Of Trustees Of The Leland Stanford Junior University Microfluidic waveguide detector
FR2970079B1 (fr) 2010-12-29 2022-08-12 Genewave Dispositif de type biopuce
US20130201316A1 (en) 2012-01-09 2013-08-08 May Patents Ltd. System and method for server based control
DE102017211910A1 (de) * 2017-07-12 2019-01-17 Dr. Johannes Heidenhain Gmbh Diffraktiver Biosensor
EP3652721A1 (de) 2017-09-04 2020-05-20 NNG Software Developing and Commercial LLC Verfahren und vorrichtung zum sammeln und verwenden von sensordaten von einem fahrzeug
US12179011B2 (en) 2018-08-14 2024-12-31 Neurotrigger Ltd. Method and apparatus for transcutaneous facial nerve stimulation and applications thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE364371B (de) * 1969-01-24 1974-02-18 Western Electric Co
FR2193990B1 (de) * 1972-07-25 1976-01-16 Thomson Csf Fr
US3883221A (en) * 1974-02-01 1975-05-13 Bell Telephone Labor Inc Portable prism-grating coupler
US4059338A (en) * 1975-09-09 1977-11-22 Sharp Kabushiki Kaisha Integrated optical waveguide coupler
JPS5821213A (ja) * 1981-07-31 1983-02-08 Canon Inc 光結合装置
WO1983001112A1 (en) * 1981-09-18 1983-03-31 Carter, Timothy Method for the determination of species in solution with an optical wave-guide
US4582809A (en) * 1982-06-14 1986-04-15 Myron J. Block Apparatus including optical fiber for fluorescence immunoassay
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
GB2146788B (en) * 1983-09-20 1986-09-24 Stc Plc Prism coupling to flat waveguides
US4565422A (en) * 1983-11-30 1986-01-21 Gte Laboratories Incorporated Surface plasmon coupler
GB2156970B (en) * 1984-01-06 1987-09-16 Plessey Co Plc Optical detection of specific molecules

Also Published As

Publication number Publication date
EP0205236A2 (de) 1986-12-17
GB8608448D0 (en) 1986-05-14
DE3687543T2 (de) 1993-05-13
EP0205236B1 (de) 1993-01-20
GB2174802A (en) 1986-11-12
EP0205236A3 (en) 1989-05-24
DE3687543D1 (de) 1993-03-04
JPS61292044A (ja) 1986-12-22
GB2174802B (en) 1989-08-02
GB8509491D0 (en) 1985-05-15
JPH07117486B2 (ja) 1995-12-18
US4857273A (en) 1989-08-15

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