ATE85435T1 - Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels. - Google Patents

Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels.

Info

Publication number
ATE85435T1
ATE85435T1 AT87308392T AT87308392T ATE85435T1 AT E85435 T1 ATE85435 T1 AT E85435T1 AT 87308392 T AT87308392 T AT 87308392T AT 87308392 T AT87308392 T AT 87308392T AT E85435 T1 ATE85435 T1 AT E85435T1
Authority
AT
Austria
Prior art keywords
lipo
metabolism
test procedure
diagnostic system
determining abnormal
Prior art date
Application number
AT87308392T
Other languages
English (en)
Inventor
Richard S Smith
Doreen M Hogle
Linda K Curtiss
Joseph L Witztum
Stephen Young
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Application granted granted Critical
Publication of ATE85435T1 publication Critical patent/ATE85435T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)
AT87308392T 1986-09-29 1987-09-22 Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels. ATE85435T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/913,140 US4828986A (en) 1986-09-29 1986-09-29 Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample
EP87308392A EP0262854B1 (de) 1986-09-29 1987-09-22 Testverfahren und diagnostisches System zur Bestimmung des abnormalen Fettstoffwechsels

Publications (1)

Publication Number Publication Date
ATE85435T1 true ATE85435T1 (de) 1993-02-15

Family

ID=25432962

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87308392T ATE85435T1 (de) 1986-09-29 1987-09-22 Testverfahren und diagnostisches system zur bestimmung des abnormalen fettstoffwechsels.

Country Status (17)

Country Link
US (1) US4828986A (de)
EP (1) EP0262854B1 (de)
JP (1) JP2656774B2 (de)
AT (1) ATE85435T1 (de)
AU (1) AU611096B2 (de)
CA (1) CA1285869C (de)
DE (1) DE3783991T2 (de)
DK (1) DK173724B1 (de)
ES (1) ES2053555T3 (de)
FI (1) FI89214C (de)
GR (1) GR3008027T3 (de)
IE (1) IE60119B1 (de)
IL (1) IL83938A (de)
NO (1) NO173902C (de)
NZ (1) NZ221941A (de)
PT (1) PT85827B (de)
ZA (1) ZA876970B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3751182T2 (de) * 1986-08-06 1995-10-26 Scripps Clinic Res Monoklonale Antikörper, B-spezifisch für Apolipoprotein, die von zwei Hybridomen erzeugt werden.
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
AU621575B2 (en) * 1987-11-02 1992-03-19 Scripps Clinic And Research Foundation Diagnostic methods and systems for quantifying apo ai
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
US5179008A (en) * 1989-02-09 1993-01-12 Wisconsin Alumni Research Foundation Hybridoma and monoclonal antibody to FHAP
US5473039A (en) * 1989-08-18 1995-12-05 The Scripps Research Institute Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs
US5168045A (en) * 1989-08-18 1992-12-01 The Scripps Research Institute Diagnostic systems and methods using polypeptide analogs of apolipoprotein e
AU662885B2 (en) * 1990-06-07 1995-09-21 Scripps Research Institute, The APO AI polypeptides, antibodies, and immunoassays
AU9088891A (en) * 1990-11-29 1992-06-25 John E. Carbaugh Diagnostic and therapeutic compositions and methods for lipoprotein(a)
ES2083152T3 (es) * 1990-11-30 1996-04-01 Monoclonetics Int Metodos para el diagnostico de dolores cronicos lumbares y cervicales.
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
US5408038A (en) * 1991-10-09 1995-04-18 The Scripps Research Institute Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides
AU4924193A (en) * 1992-09-24 1994-04-12 Perseptive Biosystems, Inc. Quantitative measurement of ldl
US6107045A (en) * 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
US5994061A (en) * 1995-09-29 1999-11-30 Queen's University At Kingston DNA constructs and methods for screening for increased expression of human apo AI gene
US5741647A (en) * 1996-02-16 1998-04-21 Tam; Joseph Wing On Flow through nucleic acid hybridisation uses thereof and a device thereof
US6248539B1 (en) 1997-09-05 2001-06-19 The Scripps Research Institute Porous semiconductor-based optical interferometric sensor
EP0911344B1 (de) 1997-10-15 2004-03-03 Fujirebio Inc. Monoklonaler Antikörper gegen Apo B-48, Hybridoma, und Verfahren zur Verwendung
AT5044U1 (de) * 2001-05-10 2002-02-25 Medsystems Diagnostics Gmbh Quantitativer einschritt immuntest in lyophilisierter form
US20040241744A1 (en) * 2001-07-12 2004-12-02 Hiroaki Kohno Method of quantifying denatured lipoprotein, reagents for quantifying denatured lipoprotein, method of detecting circulatory disease and reagents for detecting circulatory disease
KR101134605B1 (ko) 2003-10-15 2012-04-09 토우다이 티엘오, 리미티드 시료의 전처리방법 및 이를 이용한 면역학적 측정방법
US7781171B2 (en) 2003-10-15 2010-08-24 Daiichi Pure Chemicals Co., Ltd. Mehod of pretreating sample and immunological assay method using the same
US7521248B2 (en) * 2007-04-20 2009-04-21 Atherotech, Inc. Apo B measurement system and method
KR102381248B1 (ko) 2011-11-11 2022-04-01 엑시스-시일드 에이에스 혈액 샘플 분석 방법
CN118047854B (zh) * 2024-02-26 2024-08-02 武汉鹰达生物科技有限公司 一种人载脂蛋白a-i的分离纯化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2061282B (en) * 1979-10-22 1983-03-30 Symphar Sa Method for the clinical separation of a-and lipoproteins and kit for carrying out this method
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体
JPS60253871A (ja) * 1984-05-30 1985-12-14 Nippon Koutai Kenkyusho:Kk 抗アポａ−１抗体
WO1986004144A1 (en) * 1984-12-31 1986-07-17 International Genetic Engineering, Inc. Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins

Also Published As

Publication number Publication date
NO874056D0 (no) 1987-09-28
FI89214C (fi) 1993-08-25
ES2053555T3 (es) 1994-08-01
DE3783991D1 (de) 1993-03-18
IL83938A0 (en) 1988-02-29
CA1285869C (en) 1991-07-09
DK509287A (da) 1988-03-30
JP2656774B2 (ja) 1997-09-24
PT85827B (pt) 1990-08-31
FI874253L (fi) 1988-03-30
DK173724B1 (da) 2001-07-30
FI874253A0 (fi) 1987-09-28
NZ221941A (en) 1989-05-29
NO173902C (no) 1994-02-16
EP0262854A2 (de) 1988-04-06
EP0262854B1 (de) 1993-02-03
FI89214B (fi) 1993-05-14
IE872605L (en) 1988-03-29
JPS63277968A (ja) 1988-11-15
ZA876970B (en) 1988-03-21
NO874056L (no) 1988-03-30
NO173902B (no) 1993-11-08
IL83938A (en) 1991-12-15
EP0262854A3 (en) 1989-12-06
GR3008027T3 (de) 1993-09-30
AU611096B2 (en) 1991-06-06
DE3783991T2 (de) 1993-06-09
US4828986A (en) 1989-05-09
PT85827A (en) 1987-10-01
IE60119B1 (en) 1994-06-01
AU7902887A (en) 1988-03-31
DK509287D0 (da) 1987-09-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time