ATE8641T1 - 11-alpha-amino-androstane. - Google Patents

11-alpha-amino-androstane.

Info

Publication number: ATE8641T1
Authority: AT; Austria
Prior art keywords: group; alkyl; alkoxy; compounds; formula
Prior art date: 1981-05-29

Application number

AT82302786T

Other languages

English (en)

Inventor

Gordon Hanley Phillipps

David Cedric Humber

George Blanch Ewan

Barry Anthony Coomber

Anthony James Pateman

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-05-29

Filing date

1982-05-28

Publication date

1984-08-15

1982-05-28 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

1984-08-15 Application granted granted Critical

1984-08-15 Publication of ATE8641T1 publication Critical patent/ATE8641T1/de

Links

-1 AMINO ANDROSTANES Chemical class 0.000 title 1
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
239000000543 intermediate Substances 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000003531 anti-dysrhythmic effect Effects 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0011—Unsubstituted amino radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT82302786T 1981-05-29 1982-05-28 11-alpha-amino-androstane. ATE8641T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8116410		1981-05-29
EP82302786A EP0066468B1 (de)	1981-05-29	1982-05-28	11-Alpha-Amino-androstane

Publications (1)

Publication Number	Publication Date
ATE8641T1 true ATE8641T1 (de)	1984-08-15

Family

ID=10522121

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT82302786T ATE8641T1 (de)	1981-05-29	1982-05-28	11-alpha-amino-androstane.

Country Status (7)

Country	Link
US (1)	US4497805A (de)
EP (1)	EP0066468B1 (de)
JP (1)	JPS57203100A (de)
AT (1)	ATE8641T1 (de)
AU (1)	AU8428782A (de)
DE (1)	DE3260462D1 (de)
ZA (1)	ZA823783B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1212835B (it) *	1983-08-18	1989-11-30	Lehner Ag	Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
US4968675A (en) *	1988-10-28	1990-11-06	Upjohn	Non-hemolytic lazaroid parenteral formulation
IT1277700B1 (it) *	1995-12-22	1997-11-11	Poli Ind Chimica Spa	Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1581234A (en) *	1976-04-05	1980-12-10	Glaxo Operations Ltd	11a - amino - 3a - hydroxysteroids
GB1581235A (en) *	1977-04-04	1980-12-10	Glaxo Operations Ltd	11a-amino-3a-hydroxy-steroids
DK315181A (da) *	1980-07-16	1982-01-17	Glaxo Group Ltd	Fremgangsmaade til fremstilling af 11alfaaminoandrostaner
US4352798A (en) *	1980-07-16	1982-10-05	Glaxo Group Limited	11 α-Amino-androstanes

1982
- 1982-05-28 DE DE8282302786T patent/DE3260462D1/de not_active Expired
- 1982-05-28 EP EP82302786A patent/EP0066468B1/de not_active Expired
- 1982-05-28 JP JP57089996A patent/JPS57203100A/ja active Pending
- 1982-05-28 AU AU84287/82A patent/AU8428782A/en not_active Abandoned
- 1982-05-28 AT AT82302786T patent/ATE8641T1/de not_active IP Right Cessation
- 1982-05-28 ZA ZA823783A patent/ZA823783B/xx unknown
1983
- 1983-03-16 US US06/475,899 patent/US4497805A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ZA823783B (en)	1983-03-30
DE3260462D1 (en)	1984-08-30
JPS57203100A (en)	1982-12-13
EP0066468B1 (de)	1984-07-25
US4497805A (en)	1985-02-05
EP0066468A1 (de)	1982-12-08
AU8428782A (en)	1982-12-02

Legal Events

Date	Code	Title	Description
1985-03-15	UEP	Publication of translation of european patent specification
1986-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0463560T3 (da)	1995-12-04	Nye antiepileptiske midler
MX9204139A (es)	1993-01-01	Nuevos derivados de bencimidazolona, procedimiento para su preparacion y composicion farmaceutica que los contiene.
ES2018832B3 (es)	1991-05-16	Derivados de amida.
NO152047C (no)	1985-07-24	Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin
SE8604950L (sv)	1987-05-20	Demensforbettrande och terapeutiska medel
FI833453A0 (fi)	1983-09-26	Terapeutiska medel
NO156370C (no)	1987-09-09	Analogifremgangsmte ved fremstilling av terapeutisk virksomme polyolefiniske-alfa-alkyl-carboxylsyrer.
ES2129073T3 (es)	1999-06-01	Derivados del acido 4-fenilcarbamoil-3-isoxazol-carboxilico con actividad antiinflamatoria.
BR8400233A (pt)	1984-08-28	Composicao ativa contra acaros,mosca branca e tripes,composicao farmaceutica,processo para preparacao de composicao ativa,processo para controle de acaros,mosca brance e tripes,processo para combater tumores em seres vivos,compostos de benzoilureia e seu processo de preparacao
DE3260462D1 (en)	1984-08-30	11-alpha-amino-androstanes
ATE9333T1 (de)	1984-09-15	Substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.
SE8104393L (sv)	1982-01-17	Llalfa-amino-androstaner
SE7904543L (sv)	1979-12-01	Nya joniska bensen-polyjodidderivat for anvendning som kontrastmedel vid rontgenbehandling
ATE25523T1 (de)	1987-03-15	Bicyclische phenolether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel.
CU21558A3 (en)	1987-07-02	Obtainment procedure of acrydanone
SE8300686L (sv)	1983-08-12	Herbicidala kompositioner