ATE87104T1 - Test fuer sulfhydrylaminosaeure und verfahren zum nachweis und zur unterscheidung von cobalamin und folsaeure. - Google Patents

Test fuer sulfhydrylaminosaeure und verfahren zum nachweis und zur unterscheidung von cobalamin und folsaeure.

Info

Publication number: ATE87104T1
Authority: AT; Austria
Prior art keywords: acid; cobalamin; sulfhydrylamino; fols; distinguishing
Prior art date: 1986-11-20

Application number

AT87310138T

Other languages

English (en)

Inventor

Robert H Allen

Sally P Stabler

John Lindenbaum

Original Assignee

University Patents Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-20

Filing date

1987-11-17

Publication date

1993-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25464166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE87104(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-11-17 Application filed by University Patents Inc filed Critical University Patents Inc

1993-04-15 Application granted granted Critical

1993-04-15 Publication of ATE87104T1 publication Critical patent/ATE87104T1/de

Links

239000002253 acid Substances 0.000 title 2
ASARMUCNOOHMLO-WLORSUFZSA-L cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2s)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O ASARMUCNOOHMLO-WLORSUFZSA-L 0.000 title 1
FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
210000001124 body fluid Anatomy 0.000 abstract 1
239000010839 body fluid Substances 0.000 abstract 1
FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 1
230000007812 deficiency Effects 0.000 abstract 1
229940014144 folate Drugs 0.000 abstract 1
OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 1
235000019152 folic acid Nutrition 0.000 abstract 1
239000011724 folic acid Substances 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
- G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/18—Sulfur containing
- Y10T436/182—Organic or sulfhydryl containing [e.g., mercaptan, hydrogen, sulfide, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Microbiology (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Bioinformatics & Computational Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
Nutrition Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Obesity (AREA)
Investigating Or Analysing Biological Materials (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Sampling And Sample Adjustment (AREA)

AT87310138T 1986-11-20 1987-11-17 Test fuer sulfhydrylaminosaeure und verfahren zum nachweis und zur unterscheidung von cobalamin und folsaeure. ATE87104T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/933,553 US4940658A (en)	1986-11-20	1986-11-20	Assay for sulfhydryl amino acids and methods for detecting and distinguishing cobalamin and folic acid deficency
EP87310138A EP0269352B1 (de)	1986-11-20	1987-11-17	Test für Sulfhydrylaminosäure und Verfahren zum Nachweis und zur Unterscheidung von Cobalamin und Folsäure

Publications (1)

Publication Number	Publication Date
ATE87104T1 true ATE87104T1 (de)	1993-04-15

Family

ID=25464166

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT87310138T ATE87104T1 (de)	1986-11-20	1987-11-17	Test fuer sulfhydrylaminosaeure und verfahren zum nachweis und zur unterscheidung von cobalamin und folsaeure.
AT91203329T ATE139344T1 (de)	1986-11-20	1987-11-17	Verfahren zum nachweis eines cobalamin- und folsäuredefizits

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT91203329T ATE139344T1 (de)	1986-11-20	1987-11-17	Verfahren zum nachweis eines cobalamin- und folsäuredefizits

Country Status (7)

Country	Link
US (1)	US4940658A (de)
EP (2)	EP0269352B1 (de)
JP (3)	JP2574339B2 (de)
AT (2)	ATE87104T1 (de)
CA (1)	CA1298536C (de)
DE (2)	DE3784852T2 (de)
HK (1)	HK1007799A1 (de)

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CN116818966A (zh) *	2023-06-29	2023-09-29	山东英盛生物技术有限公司	Lc-ms/ms测定甲基丙二酸、同型半胱氨酸及其相关代谢产物方法

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1986
- 1986-11-20 US US06/933,553 patent/US4940658A/en not_active Expired - Lifetime
1987
- 1987-11-17 EP EP87310138A patent/EP0269352B1/de not_active Expired - Lifetime
- 1987-11-17 AT AT87310138T patent/ATE87104T1/de not_active IP Right Cessation
- 1987-11-17 EP EP91203329A patent/EP0486118B1/de not_active Expired - Lifetime
- 1987-11-17 AT AT91203329T patent/ATE139344T1/de not_active IP Right Cessation
- 1987-11-17 DE DE8787310138T patent/DE3784852T2/de not_active Expired - Fee Related
- 1987-11-17 DE DE3751840T patent/DE3751840T2/de not_active Expired - Fee Related
- 1987-11-19 CA CA000552222A patent/CA1298536C/en not_active Expired - Lifetime
- 1987-11-20 JP JP62292190A patent/JP2574339B2/ja not_active Expired - Lifetime
1994
- 1994-04-26 JP JP6088530A patent/JP2579434B2/ja not_active Expired - Fee Related
1995
- 1995-07-07 JP JP7171988A patent/JP2577878B2/ja not_active Expired - Fee Related
1998
- 1998-06-26 HK HK98107047A patent/HK1007799A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0269352A3 (en)	1988-07-06
JPS63221249A (ja)	1988-09-14
HK1007799A1 (en)	1999-04-23
JPH0854398A (ja)	1996-02-27
DE3784852T2 (de)	1993-06-24
EP0269352B1 (de)	1993-03-17
DE3751840D1 (de)	1996-07-18
US4940658A (en)	1990-07-10
DE3784852D1 (de)	1993-04-22
CA1298536C (en)	1992-04-07
DE3751840T2 (de)	1997-01-09
JPH0749348A (ja)	1995-02-21
JP2577878B2 (ja)	1997-02-05
EP0486118A1 (de)	1992-05-20
JP2574339B2 (ja)	1997-01-22
ATE139344T1 (de)	1996-06-15
EP0486118B1 (de)	1996-06-12
EP0269352A2 (de)	1988-06-01
JP2579434B2 (ja)	1997-02-05

Legal Events

Date	Code	Title	Description
1993-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE87104T1 (de)	1993-04-15	Test fuer sulfhydrylaminosaeure und verfahren zum nachweis und zur unterscheidung von cobalamin und folsaeure.
DE3587582D1 (de)	1993-10-21	Gerät und Verfahren zum selbsttätigen Inspizieren von Objekten und zum Identifizieren oder Erkennen bekannter und unbekannter Teile davon, einschliesslich Fehler und dergleichen.
DE69033796D1 (de)	2001-10-18	Verfahren und gerät zum nachweis und zur quantifizierung von glukose in körperflüssigkeiten
ATE202801T1 (de)	2001-07-15	Verfahren zum nachweis, identifizieren und quantifizieren von organismen und viren
ATE76508T1 (de)	1992-06-15	Vorrichtung zur feststellung von okkultem blut.
DE3770784D1 (de)	1991-07-18	Verfahren und einrichtung zur detektion von korrosion oder dergleichen.
DE3687220D1 (de)	1993-01-14	Verfahren und vorrichtung zur detektion von musterfehlern.
ATE59412T1 (de)	1991-01-15	Charakterisierung von onkogenen und darauf beruhende bestimmungen.
DE3486226D1 (de)	1993-11-11	Verfahren und vorrichtung zur echtzeit-hochgeschwindigkeitsprüfung von objekten zum identifizieren oder erkennen bekannter und unbekannter teile davon, einschliesslich fehler und dergleichen.
DE3671298D1 (de)	1990-06-21	Verfahren zur konzentrationsbestimmung einer komponente in gasen und elektrochemische einrichtung, geeignet zur durchfuehrung des verfahrens.
DE3575621D1 (de)	1990-03-01	Verfahren und anordnung zum kennzeichnen und erkennen von gegenstaenden.
DE3676974D1 (de)	1991-02-21	Verfahren zur quantitativen messung von kohlenwasserstoffen.
DE3872932D1 (de)	1992-08-27	Geraet und verfahren zur detektion oberflaechenfehler.
ATE72567T1 (de)	1992-02-15	Oligonukleotid-sonden und verfahren zum nachweis mittels hybridisierung von nukleinsaeuren in bakterien und anderen lebewesen.
DE3684194D1 (de)	1992-04-16	Messfuehler und verfahren zum nachweis und zur quantitativen bestimmung von kraft- und drehmomentkomponenten.
DE3576853D1 (de)	1990-05-03	Ultraschall-koagulationsanzeiger und methode zum nachweis des eintretens von koagulation.
DE3855403D1 (de)	1996-08-14	Gerät zur berührungslosen Remissionsmessung
EP0530009A3 (en)	1993-11-03	Method of characterising genomic dna
DE3851329D1 (de)	1994-10-06	Verfahren und vorrichtung zum sammeln von blutmustern.
DE3675413D1 (de)	1990-12-13	Vorrichtung und verfahren zur pruefung des spezifischen widerstandes.
DE3680359D1 (de)	1991-08-29	Vorrichtung zum nachweis von teilchen.
DE3888653D1 (de)	1994-04-28	Verfahren und Testsatz zum Nachweis einer Nukleinsäure-Sequenz.
DE3673041D1 (de)	1990-09-06	Verfahren und vorrichtung zum detektieren blatt- oder folienfoermiger gegenstaende.
DE3672821D1 (de)	1990-08-23	Vorrichtung und verfahren zum nachweis mehrerer blaetter.
AT399596B (de)	1995-06-26	Verfahren und vorrichtung zum bestimmen des orts von in flachglas vorhandenen fehlern