ATE87290T1 - Radiohalogenierte kleine molekuele fuer das markieren von proteinen. - Google Patents

Radiohalogenierte kleine molekuele fuer das markieren von proteinen.

Info

Publication number: ATE87290T1
Authority: AT; Austria
Prior art keywords: protein; compounds; small molecules; radiohalogenated; metalated
Prior art date: 1985-05-17

Application number

AT86303757T

Other languages

English (en)

Inventor

Daniel Scott Wilbur

Alan Richard Fritzberg

David Schuster Jones

Original Assignee

Neorx Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-17

Filing date

1986-05-16

Publication date

1993-04-15

1986-05-16 Application filed by Neorx Corp filed Critical Neorx Corp

1993-04-15 Application granted granted Critical

1993-04-15 Publication of ATE87290T1 publication Critical patent/ATE87290T1/de

Links

102000004169 proteins and genes Human genes 0.000 title abstract 5
108090000623 proteins and genes Proteins 0.000 title abstract 5
150000003384 small molecules Chemical class 0.000 title abstract 2
238000002372 labelling Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
125000003118 aryl group Chemical group 0.000 abstract 2
125000000524 functional group Chemical group 0.000 abstract 2
125000002524 organometallic group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000021615 conjugation Effects 0.000 abstract 1
238000007324 demetalation reaction Methods 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
125000003106 haloaryl group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
BRMYZIKAHFEUFJ-UHFFFAOYSA-L mercury diacetate Chemical compound CC(=O)O[Hg]OC(C)=O BRMYZIKAHFEUFJ-UHFFFAOYSA-L 0.000 abstract 1
239000002243 precursor Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
- C07F3/12—Aromatic substances containing mercury
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Investigating Or Analysing Biological Materials (AREA)

AT86303757T 1985-05-17 1986-05-16 Radiohalogenierte kleine molekuele fuer das markieren von proteinen. ATE87290T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US73539285A	1985-05-17	1985-05-17
US85274086A	1986-04-21	1986-04-21
EP86303757A EP0203764B1 (de)	1985-05-17	1986-05-16	Radiohalogenierte kleine Moleküle für das Markieren von Proteinen

Publications (1)

Publication Number	Publication Date
ATE87290T1 true ATE87290T1 (de)	1993-04-15

Family

ID=27112875

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86303757T ATE87290T1 (de)	1985-05-17	1986-05-16	Radiohalogenierte kleine molekuele fuer das markieren von proteinen.

Country Status (5)

Country	Link
EP (1)	EP0203764B1 (de)
AT (1)	ATE87290T1 (de)
DE (1)	DE3688103T2 (de)
DK (1)	DK226986A (de)
NO (1)	NO861962L (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4812577A (en) *	1987-04-28	1989-03-14	The United States Of America As Represented By The United States Department Of Energy	Mercuric acetate phenyl maleimide useful for preparing radiohalogenated maleimides
US4977288A (en) *	1988-01-29	1990-12-11	President And Fellows Of Harvard College	M-aminophenyltrialkylstannane
US5059541A (en) *	1988-04-29	1991-10-22	Neorx Corporation	Minimal derivatization of proteins
US4966999A (en) *	1988-06-07	1990-10-30	Cytogen Corporation	Radiohalogenated compounds for site specific labeling
DE68924783T2 (de) *	1988-09-30	1996-03-28	Neorx Corp	Wässrige additivsysteme, verfahren und polymerteilchen.
US5066789A (en) *	1988-09-30	1991-11-19	Neorx Corporation	Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
US5102651A (en) *	1989-12-29	1992-04-07	Neorx Corporation	Process for isolation and radiolabeling of pharmaceuticals with isotopes of astatine
US5463080A (en) *	1992-08-27	1995-10-31	Bracco International B.V.	2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents
GB0206750D0 (en)	2002-03-22	2002-05-01	Amersham Plc	Radiofluorination methods
PL3157577T3 (pl)	2014-06-18	2021-04-19	Alpha Therapy Solutions Ab	Automatyczna platforma technologii produkcji radiofarmaceutyków astatyna-211 [at-211]

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3979506A (en) *	1974-10-11	1976-09-07	Pierce Chemical Company	Radioactive compounds for labeling proteins
DE2965469D1 (en) *	1978-11-29	1983-07-07	Hoffmann La Roche	Radioiodine containing amines, their preparation and their use as brain imaging agents
DE2947500C2 (de)	1979-11-24	1984-05-10	Dutschka, Klaus, 4300 Essen	Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber

1986
- 1986-05-16 EP EP86303757A patent/EP0203764B1/de not_active Expired - Lifetime
- 1986-05-16 AT AT86303757T patent/ATE87290T1/de not_active IP Right Cessation
- 1986-05-16 NO NO861962A patent/NO861962L/no unknown
- 1986-05-16 DE DE8686303757T patent/DE3688103T2/de not_active Expired - Fee Related
- 1986-05-16 DK DK226986A patent/DK226986A/da unknown

Also Published As

Publication number	Publication date
EP0203764A3 (en)	1990-03-28
DE3688103T2 (de)	1993-07-15
EP0203764A2 (de)	1986-12-03
EP0203764B1 (de)	1993-03-24
DK226986A (da)	1986-11-18
DE3688103D1 (de)	1993-04-29
NO861962L (no)	1986-11-18
DK226986D0 (da)	1986-05-16

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Legal Events

Date	Code	Title	Description
2005-02-15	REN	Ceased due to non-payment of the annual fee