DK226986A - Radiohalogenerede smaa molekyler til proteinmaerkning - Google Patents

Radiohalogenerede smaa molekyler til proteinmaerkning Download PDF

Info

Publication number: DK226986A
Authority: DK; Denmark
Prior art keywords: protein; compounds; small molecules; metalated; functional group
Prior art date: 1985-05-17

Application number

DK226986A

Other languages

Danish (da)

English (en)

Other versions

DK226986D0 (da

Inventor

Daniel Scott Wilbur

Alan Richard Fritzberg

David Schuster Jones

Original Assignee

Neorx Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-17

Filing date

1986-05-16

Publication date

1986-11-18

1986-05-16 Application filed by Neorx Corp filed Critical Neorx Corp

1986-05-16 Publication of DK226986D0 publication Critical patent/DK226986D0/da

1986-11-18 Publication of DK226986A publication Critical patent/DK226986A/da

Links

102000004169 proteins and genes Human genes 0.000 title abstract 5
108090000623 proteins and genes Proteins 0.000 title abstract 5
150000003384 small molecules Chemical class 0.000 title abstract 2
238000002372 labelling Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
125000003118 aryl group Chemical group 0.000 abstract 2
125000000524 functional group Chemical group 0.000 abstract 2
125000002524 organometallic group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000021615 conjugation Effects 0.000 abstract 1
238000007324 demetalation reaction Methods 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
125000003106 haloaryl group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
BRMYZIKAHFEUFJ-UHFFFAOYSA-L mercury diacetate Chemical compound CC(=O)O[Hg]OC(C)=O BRMYZIKAHFEUFJ-UHFFFAOYSA-L 0.000 abstract 1
239000002243 precursor Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
- C07F3/12—Aromatic substances containing mercury
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Investigating Or Analysing Biological Materials (AREA)

DK226986A 1985-05-17 1986-05-16 Radiohalogenerede smaa molekyler til proteinmaerkning DK226986A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73539285A	1985-05-17	1985-05-17
US85274086A	1986-04-21	1986-04-21

Publications (2)

Publication Number	Publication Date
DK226986D0 DK226986D0 (da)	1986-05-16
DK226986A true DK226986A (da)	1986-11-18

Family

ID=27112875

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK226986A DK226986A (da)	1985-05-17	1986-05-16	Radiohalogenerede smaa molekyler til proteinmaerkning

Country Status (5)

Country	Link
EP (1)	EP0203764B1 (de)
AT (1)	ATE87290T1 (de)
DE (1)	DE3688103T2 (de)
DK (1)	DK226986A (de)
NO (1)	NO861962L (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4812577A (en) *	1987-04-28	1989-03-14	The United States Of America As Represented By The United States Department Of Energy	Mercuric acetate phenyl maleimide useful for preparing radiohalogenated maleimides
US4977288A (en) *	1988-01-29	1990-12-11	President And Fellows Of Harvard College	M-aminophenyltrialkylstannane
US5059541A (en) *	1988-04-29	1991-10-22	Neorx Corporation	Minimal derivatization of proteins
US4966999A (en) *	1988-06-07	1990-10-30	Cytogen Corporation	Radiohalogenated compounds for site specific labeling
WO1990003401A1 (en) *	1988-09-30	1990-04-05	Neorx Corporation	Targeting substance-diagnostic/therapeutic agent conjugates having schiff base linkages
US5066789A (en) *	1988-09-30	1991-11-19	Neorx Corporation	Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
US5102651A (en) *	1989-12-29	1992-04-07	Neorx Corporation	Process for isolation and radiolabeling of pharmaceuticals with isotopes of astatine
US5463080A (en) *	1992-08-27	1995-10-31	Bracco International B.V.	2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents
GB0206750D0 (en)	2002-03-22	2002-05-01	Amersham Plc	Radiofluorination methods
CN107073141B (zh)	2014-06-18	2021-06-29	斯图雷·林德格伦	用于生产砹-211（At-211）放射性药剂的自动处理平台

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3979506A (en) *	1974-10-11	1976-09-07	Pierce Chemical Company	Radioactive compounds for labeling proteins
JPS5932457B2 (ja)	1978-11-29	1984-08-09	エフ・ホフマン−ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト	放射性ヨウ素化アミン
DE2947500C2 (de)	1979-11-24	1984-05-10	Dutschka, Klaus, 4300 Essen	Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber

1986
- 1986-05-16 EP EP86303757A patent/EP0203764B1/de not_active Expired - Lifetime
- 1986-05-16 DE DE8686303757T patent/DE3688103T2/de not_active Expired - Fee Related
- 1986-05-16 AT AT86303757T patent/ATE87290T1/de not_active IP Right Cessation
- 1986-05-16 DK DK226986A patent/DK226986A/da unknown
- 1986-05-16 NO NO861962A patent/NO861962L/no unknown

Also Published As

Publication number	Publication date
EP0203764A3 (en)	1990-03-28
DE3688103D1 (de)	1993-04-29
EP0203764A2 (de)	1986-12-03
EP0203764B1 (de)	1993-03-24
DE3688103T2 (de)	1993-07-15
NO861962L (no)	1986-11-18
ATE87290T1 (de)	1993-04-15
DK226986D0 (da)	1986-05-16

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