ATE87503T1 - Liposomes praeparat und antibiotikum. - Google Patents

Liposomes praeparat und antibiotikum.

Info

Publication number: ATE87503T1
Authority: AT; Austria
Prior art keywords: liposomes; preparative; antibiotic; aminoglycoside; phosphate
Prior art date: 1986-12-23

Application number

AT87901176T

Other languages

English (en)

Inventor

Marcel B Bally

Lois E Bolcsak

Pieter R Cullis

Andrew S Janoff

Lawrence D Mayer

Robert P Lenk

Jo Ann Jedrusiak

Original Assignee

Liposome Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-23

Filing date

1987-01-13

Publication date

1993-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27130236&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE87503(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-01-13 Application filed by Liposome Co Inc filed Critical Liposome Co Inc

1993-04-15 Application granted granted Critical

1993-04-15 Publication of ATE87503T1 publication Critical patent/ATE87503T1/de

Links

239000002502 liposome Substances 0.000 title abstract 2
230000003115 biocidal effect Effects 0.000 title 1
229940126575 aminoglycoside Drugs 0.000 abstract 2
229910019142 PO4 Inorganic materials 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Oncology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Reproductive Health (AREA)
Communicable Diseases (AREA)
Dispersion Chemistry (AREA)
Urology & Nephrology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Manufacturing Of Micro-Capsules (AREA)
Saccharide Compounds (AREA)

AT87901176T 1986-12-23 1987-01-13 Liposomes praeparat und antibiotikum. ATE87503T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US94639186A	1986-12-23	1986-12-23
US94639886A	1986-12-23	1986-12-23
EP87901176A EP0295248B2 (de)	1986-12-23	1987-01-13	Liposomes präparat und antibiotikum
PCT/US1987/000077 WO1988004573A1 (en)	1986-12-23	1987-01-13	Liposome preparation and antibiotic

Publications (1)

Publication Number	Publication Date
ATE87503T1 true ATE87503T1 (de)	1993-04-15

Family

ID=27130236

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT92106331T ATE141166T1 (de)	1986-12-23	1987-01-13	Guanidinaminoglycosid enthaltende liposome
AT87901176T ATE87503T1 (de)	1986-12-23	1987-01-13	Liposomes praeparat und antibiotikum.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT92106331T ATE141166T1 (de)	1986-12-23	1987-01-13	Guanidinaminoglycosid enthaltende liposome

Country Status (8)

Country	Link
EP (3)	EP0498471B1 (de)
JP (1)	JP2528153B2 (de)
AT (2)	ATE141166T1 (de)
AU (1)	AU609711B2 (de)
CA (1)	CA1314481C (de)
DE (3)	DE3785198T3 (de)
IL (2)	IL97538A (de)
WO (1)	WO1988004573A1 (de)

Families Citing this family (47)

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US4920016A (en) *	1986-12-24	1990-04-24	Linear Technology, Inc.	Liposomes with enhanced circulation time
US5269979A (en) *	1988-06-08	1993-12-14	Fountain Pharmaceuticals, Inc.	Method for making solvent dilution microcarriers
CA1340241C (en) *	1988-06-08	1998-12-15	Fountain Pharmaceuticals, Inc.	Method for marking solvent dilution microcarriers
BE1001869A3 (fr) *	1988-10-12	1990-04-03	Franz Legros	Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US5843473A (en) *	1989-10-20	1998-12-01	Sequus Pharmaceuticals, Inc.	Method of treatment of infected tissues
CA2046997C (en) *	1990-07-16	2000-12-12	Hiroshi Kikuchi	Liposomal products
US6060080A (en) *	1990-07-16	2000-05-09	Daiichi Pharmaceutical Co., Ltd.	Liposomal products
PT100486B (pt) *	1992-05-14	1999-07-30	Ineti Inst Nac Engenh E Tecnol	Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao
WO1994012155A1 (en) *	1992-12-02	1994-06-09	Vestar, Inc.	Antibiotic formulation and process
US5958449A (en) *	1992-12-02	1999-09-28	Nexstar Pharmaceuticals, Inc.	Antibiotic formulation and use for bacterial infections
CN1040177C (zh) *	1993-04-23	1998-10-14	江苏省微生物研究所	一种含1-N-乙基庆大霉素C1a或其盐的药用制剂及制备方法
US5759571A (en) *	1993-05-11	1998-06-02	Nexstar Pharmaceuticals, Inc.	Antibiotic formulation and use for drug resistant infections
AU686277B2 (en) *	1993-11-16	1998-02-05	Pacira Pharmaceuticals, Inc.	Vesicles with controlled release of actives
US6613352B2 (en)	1999-04-13	2003-09-02	Universite De Montreal	Low-rigidity liposomal formulation
EP1404297B1 (de)	2001-06-12	2011-04-27	The Johns Hopkins University School Of Medicine	Reservoirvorrichtung für die intraokulare arzneimittelabgabe
US20050085432A1 (en) *	2001-12-26	2005-04-21	Aviva Lapidot	Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
PT1581236E (pt) *	2002-10-29	2013-12-24	Insmed Inc	Libertação prolongada de anti-infecciosos
US7718189B2 (en)	2002-10-29	2010-05-18	Transave, Inc.	Sustained release of antiinfectives
EP3067047B1 (de)	2005-12-08	2022-04-20	Insmed Incorporated	Antiinfektive zusammensetzungen auf lipidbasis zur behandlung von lungeninfekten
WO2008137717A1 (en)	2007-05-04	2008-11-13	Transave, Inc.	Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9114081B2 (en)	2007-05-07	2015-08-25	Insmed Incorporated	Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en)	2007-05-07	2016-05-10	Insmed Incorporated	Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en)	2007-05-07	2015-09-01	Insmed Incorporated	Method of treating pulmonary disorders with liposomal amikacin formulations
US8623395B2 (en)	2010-01-29	2014-01-07	Forsight Vision4, Inc.	Implantable therapeutic device
AU2010208046B2 (en)	2009-01-29	2014-10-02	Forsight Vision4, Inc.	Posterior segment drug delivery
WO2013022801A1 (en)	2011-08-05	2013-02-14	Forsight Vision4, Inc.	Small molecule delivery with implantable therapeutic device
CN103209664A (zh)	2010-08-05	2013-07-17	弗赛特影像4股份有限公司	可植入的治疗装置
AU2011285548B2 (en)	2010-08-05	2014-02-06	Forsight Vision4, Inc.	Combined drug delivery methods and apparatus
EP3861969A1 (de)	2010-08-05	2021-08-11	ForSight Vision4, Inc.	Injektorvorrichtung zur arzneimittelabgabe
WO2012068549A2 (en)	2010-11-19	2012-05-24	Forsight Vision4, Inc.	Therapeutic agent formulations for implanted devices
US10398592B2 (en)	2011-06-28	2019-09-03	Forsight Vision4, Inc.	Diagnostic methods and apparatus
PT2755600T (pt)	2011-09-16	2021-04-19	Forsight Vision4 Inc	Aparelhos de troca de fluidos
WO2013116061A1 (en)	2012-02-03	2013-08-08	Forsight Vision4, Inc.	Insertion and removal methods and apparatus for therapeutic devices
PL2852391T3 (pl)	2012-05-21	2022-04-11	Insmed Incorporated	Układy do leczenia infekcji płuc
US10124066B2 (en)	2012-11-29	2018-11-13	Insmed Incorporated	Stabilized vancomycin formulations
WO2014152959A1 (en)	2013-03-14	2014-09-25	Forsight Vision4, Inc.	Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
CN105246438B (zh)	2013-03-28	2018-01-26	弗赛特影像4股份有限公司	用于输送治疗物质的眼科植入物
LT3466432T (lt)	2014-05-15	2020-12-28	Insmed Incorporated	Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti
ES2803102T3 (es)	2014-07-15	2021-01-22	Forsight Vision4 Inc	Dispositivo de administración de implante ocular
RU2017105844A (ru)	2014-08-08	2018-09-11	Форсайт Вижн4, Инк.	Стабильные и растворимые составы ингибиторов рецепторных тирозинкиназ и способы их получения
CN110478119B (zh)	2014-11-10	2022-04-15	弗赛特影像4股份有限公司	可膨胀药物递送装置和使用方法
WO2017087902A1 (en)	2015-11-20	2017-05-26	Forsight Vision4, Inc.	Porous structures for extended release drug delivery devices
CN113017981B (zh)	2016-04-05	2023-07-25	弗赛特影像4股份有限公司	药物递送装置
CN111655206B (zh)	2017-11-21	2022-10-14	弗赛特影像4股份有限公司	用于可扩展端口递送系统的流体交换装置及使用方法
EP3773505B1 (de)	2018-03-30	2026-04-29	Insmed Incorporated	Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten
JP7449275B2 (ja)	2018-05-02	2024-03-13	インスメッドインコーポレイテッド	リポソーム薬物製剤の製造方法
USD1033637S1 (en)	2022-01-24	2024-07-02	Forsight Vision4, Inc.	Fluid exchange device

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3993754A (en) *	1974-10-09	1976-11-23	The United States Of America As Represented By The United States Energy Research And Development Administration	Liposome-encapsulated actinomycin for cancer chemotherapy
JPS5186117A (en) *	1975-01-27	1976-07-28	Tanabe Seiyaku Co	Johoseibiryushiseizainoseiho
US4086257A (en) *	1976-10-12	1978-04-25	Sears Barry D	Phosphatidyl quaternary ammonium compounds
CH624011A5 (de) *	1977-08-05	1981-07-15	Battelle Memorial Institute
US4235871A (en) *	1978-02-24	1980-11-25	Papahadjopoulos Demetrios P	Method of encapsulating biologically active materials in lipid vesicles
US4397846A (en) *	1981-05-15	1983-08-09	Murray Weiner	Storage-stable lipid vesicles and method of preparation
US4522803A (en) *	1983-02-04	1985-06-11	The Liposome Company, Inc.	Stable plurilamellar vesicles, their preparation and use
JPS59500952A (ja) *	1982-03-29	1984-05-31	ザ　リポソ−ム　カンパニ−、インコ−ポレ−テッド	安定なプルリラメラベシクル類
US4588578A (en) *	1983-08-08	1986-05-13	The Liposome Company, Inc.	Lipid vesicles prepared in a monophase
US4515736A (en) *	1983-05-12	1985-05-07	The Regents Of The University Of California	Method for encapsulating materials into liposomes
MX160365A (es) *	1983-08-31	1990-02-12	Rockwell International Corp	Mejoras a metodo para formar un piston de frenado para freno de disco
US4532089A (en) *	1984-01-14	1985-07-30	Northwestern University	Method of preparing giant size liposomes
US4610868A (en) *	1984-03-20	1986-09-09	The Liposome Company, Inc.	Lipid matrix carriers for use in drug delivery systems
JPH0655676B2 (ja) *	1984-07-26	1994-07-27	ザリポソ−ムカンパニ−、インコ−ポレ−テツド	脂質小胞体中に含有された抗菌物質の混合物による抗菌活性の増高
JPH0680767A (ja) *	1992-09-03	1994-03-22	Matsushita Electric Ind Co Ltd	電子・電気機器用エポキシ樹脂組成物

1987
- 1987-01-13 IL IL9753887A patent/IL97538A/en not_active IP Right Cessation
- 1987-01-13 JP JP62501069A patent/JP2528153B2/ja not_active Expired - Fee Related
- 1987-01-13 EP EP92106331A patent/EP0498471B1/de not_active Expired - Lifetime
- 1987-01-13 WO PCT/US1987/000077 patent/WO1988004573A1/en not_active Ceased
- 1987-01-13 AU AU69345/87A patent/AU609711B2/en not_active Ceased
- 1987-01-13 CA CA000527232A patent/CA1314481C/en not_active Expired - Fee Related
- 1987-01-13 DE DE3785198T patent/DE3785198T3/de not_active Expired - Lifetime
- 1987-01-13 EP EP19920106330 patent/EP0500143A3/en not_active Withdrawn
- 1987-01-13 EP EP87901176A patent/EP0295248B2/de not_active Expired - Lifetime
- 1987-01-13 AT AT92106331T patent/ATE141166T1/de not_active IP Right Cessation
- 1987-01-13 DE DE3751871A patent/DE3751871D1/de not_active Expired - Fee Related
- 1987-01-13 DE DE3751871T patent/DE3751871T4/de not_active Expired - Lifetime
- 1987-01-13 AT AT87901176T patent/ATE87503T1/de not_active IP Right Cessation
1991
- 1991-03-13 IL IL97538A patent/IL97538A0/xx unknown

Also Published As

Publication number	Publication date
DE3751871T4 (de)	1998-03-26
EP0295248B2 (de)	1999-04-28
ATE141166T1 (de)	1996-08-15
EP0498471A3 (en)	1993-03-03
AU6934587A (en)	1988-07-15
CA1314481C (en)	1993-03-16
DE3785198T3 (de)	1999-09-02
JP2528153B2 (ja)	1996-08-28
EP0295248A1 (de)	1988-12-21
EP0500143A3 (en)	1993-03-03
IL97538A (en)	1995-03-15
DE3751871T2 (de)	1997-03-13
DE3785198T2 (de)	1993-07-15
EP0295248A4 (de)	1988-12-19
EP0500143A2 (de)	1992-08-26
EP0498471B1 (de)	1996-08-14
DE3785198D1 (de)	1993-05-06
EP0295248B1 (de)	1993-03-31
AU609711B2 (en)	1991-05-09
JPH01501619A (ja)	1989-06-08
DE3751871D1 (de)	1996-09-19
IL97538A0 (en)	1992-06-21
EP0498471A2 (de)	1992-08-12
WO1988004573A1 (en)	1988-06-30

Legal Events

Date	Code	Title
1993-09-15	UEP	Publication of translation of european patent specification
2000-04-15	UEP	Publication of translation of european patent specification
2006-10-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE87503T1 (de)	1993-04-15	Liposomes praeparat und antibiotikum.
ATE38672T1 (de)	1988-12-15	7-oxabicycloheptan aminosubstituierte prostaglandinaehnliche verbindungen.
ZA857270B (en)	1986-05-28	Tetralin derivatives,their preparation and their use
FI830100L (fi)	1983-07-19	Nya 6-substituerade s-triazolo /3,4-a/ ftalazinderivat
IL60185A0 (en)	1980-07-31	6 , 7 ;15,16-dimethylene-1,4-androstadien-3-ones,process for their production and pharmaceutical preparations containg them
HUT45538A (en)	1988-07-28	Process for producing quinoline derivatives and pharmaceutical compositions containing them
ES8601908A1 (es)	1985-11-16	Procedimiento para la preparacion de nuevas 5,11-dihidro-6h-dibenzo (b,e)azepin-6-onas sustituidas
DE59108298D1 (de)	1996-11-28	7-(2,7-Diazabicyclo[3,3.0]octyl)-3-chinolon- und -naphthyridoncarbonsäure-Derivate
EP0331092A3 (en)	1990-11-07	Alpha-amino-carboxylic-acid derivatives, their preparation and use
BG40803A3 (bg)	1987-02-16	Метод за получаване на арилциклобутилалкиламинови производни
FI834661A0 (fi)	1983-12-19	Nya farmakologiskt aktiva pyrazolopyridiner
ES493931A0 (es)	1981-10-01	Procedimiento de preparacion de nuevos derivados de la 3,4,5-trimetoxi-cinamoil-piperazina
ZA83856B (en)	1983-11-30	Thiazaspirane derivatives,processes for their preparation,and medicaments
SE8803765D0 (sv)	1988-10-21	Nya isopolypeptider samt foerfarande foer framstaellning av desamma
FR2601019B1 (fr)	1989-05-05	Procede de preparation de derives de la moranoline
SE8400118D0 (sv)	1984-01-11	Substituted carboxy-thiazolo(3,2-a)pyrimidine derivatives and process for their preparation
FI900098L (fi)	1990-01-09	Menetelmä lääkeaineena käyttökelpoisten 5H-pyrido/1',2':4,5/tiadiatsino/2,3-a/bentsimidatsoliumjohdannaisten valmistamiseksi
BE867994A (fr)	1978-12-11	Procede de preparation de derives de l'acide methoxy-7,alpha-(dithietane-1,3-carboxamido-2)-cephalosporanique
HUT54682A (en)	1991-03-28	Process for producing 13-bromine- and 13,14-dibromine-ergoline derivatives and pharmaceutical preparatives containing these compounds
BE881764A (fr)	1980-08-18	NOUVEAUX DERIVES DE LA PYRIDO (3,4-e) -ASTRIAZINE ET PROCEDE DE PREPARATION DE CES DERIVES
FR2562074B1 (fr)	1988-08-05	Procede de preparation de derives de 2,2-bishalomethylpename
FI885033A7 (fi)	1989-05-14	Menetelmä 1,5-bentsotiatsepiinijohdannaisten valmistamiseksi
FI890065A7 (fi)	1989-07-08	Menetelmä 5,8,13,14-tetrahydrobents/5,6/isoindolo/2,1-b/isokinonliini-8,13-dionijohdannaisten valmistamiseksi
PT69181A (fr)	1979-03-01	Procede de preparation de derives d'antibiotiques
RO94422A (ro)	1988-06-30	Procedeu de preparare a derivatilor antibioticului a-21978c